• Nutrition Research and Practice
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• 제12권2호
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• pp.160-165
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• 2018

BACKGROUND/OBJECTIVES: Korea is quickly becoming an aged society. Dementia is also becoming a vital public health problem in Korea. Cognitive impairment as a pre-stage of dementia shares most risk factors for dementia. The aim of the present study was to determine associations of serum levels of vitamins A, C, and E with the risk of cognitive impairment among elderly Koreans. SUBJECTS/METHODS: In this cross-sectional study, a total of 230 participants aged 60-79 years from Yangpyeong cohort were included. Cognitive function was assessed by the Korean version of the Mini-Mental State Examination for Dementia Screening. The logistic multivariable regression model was applied to determine the effect of serum vitamins A, C, and E on the risk of cognitive impairment. RESULTS: There was no significant association between the risk of cognitive impairment and serum levels of vitamin A and vitamin C. There was a significant odd ratio when the second tertile group of beta-gamma tocopherol level was compared to the first tertile group [odds ratio (OR) = 0.37, 95% confidence interval (CI) = 0.14-0.98, P for trend = 0.051]. In subgroup analyses, there were significant negative associations between beta-gamma tocopherol level and the risk of cognitive impairment in men (OR = 0.17, 95% CI = 0.03-0.87, P for trend = 0.028), non-drinkers or former drinkers (OR = 0.13, 95% CI = 0.02-0.66, P for trend = 0.025), and non-smokers or former smokers (OR = 0.27, 95% CI = 0.09-0.82, P for trend = 0.017). CONCLUSION: Serum beta-gamma tocopherol levels tended to be inversely associated with the risk of cognitive impairment. Further prospective large-scaled studies are needed to examine this association.

• 한국학교보건학회지
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• 제8권1호
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• pp.143-154
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• 1995

Korea has been recently reducing the quality of life as well as rising medical cost because of the increase of chronic diseases. But we can prevent those chronic diseases through the improvement of environment or life style. We evaluated the educational effectiveness of chronic diseases(hypertention, diabetes, cancer, stroke and other chronic diseases) designed to increase the knowledge, attitude and practice of chronic diseases among university students. Between August 1994 and November 1994, we implemented chronic diseases prevention instruction in intervention students; unmatched control students were selected in same university. We conducted pre- and post-intervention surveys both intervention and control students with self-reported questionnaires(50 items). We assigned score(0-4 points) to items and conducted a analysis of covariance(ANCOVA) with sex, grade and economic status as the covariate, using the SAS PC computer statistical package. And we culculated odds ratio with safety scores between intervention and control students. The results of this study were followed. 1. In demographic characteristics of subjects both pre- and post intervention, we found no significant differences in intervention and control students at religion, father's education, mother's education, mother's occupation and type of residence(p>0.05), but we found significant differences at sex(p<0.001), grade(p<0.001) and economic status(p<0.05). 2. The sex, grade and economic status-adjusted mean prevention knowledge scores for diabetes and stroke increased from the pre- to post-survey in the intervention students(p<0.001), but control students did not increased(p>0.05). As odds ratios in knowledge were below 1, the knowledge of intervention students were higher than control students. 3. The attitudes for general adult health increased from the pre- to post-survey in the intervention students(p<0.05), but control students did not increased(p>0.05). As odds ratios in attitudes were approximately 1, we can not say effectiveness in intervention students 4. The pratices for cancer and stroke increased from the pre- to post-survey in both the intervention and control students(p<0.001). Also odds ratio of hypertention was 0.91, and that of stroke was 1.14. 5. Health related behaviors did not increased from the pre- to post- survey in both the intervention and control students(p>0.05). But odds ratio of drinking was 0.76 and that of body weight was 1.21. 6. Health status did not increased from the pre- to post- survey in both the intervention and control students(p>0.05). As odds ratio of health status was 1.09, prevention education was not effect in intervention students We would like to recommend as follows; 1. University students must learn about prevention of chronic diseases. Because the knowledge of invetervention students was higher than that of control students. 2. The prevention education of chronic diseases should be taught from primary school. 3. Adult health education for university students must be practiced continuously. Education period(l5 weeks) in this study was not complete. 4. The evaluation of chronic diseases was conducted real measurement(such as BP check) as well as self reported-survey. 5. Educational materials(video tape, pamphlet) related the prevention of chronic diseases should be developed at national level. And we must easely use those materials. 6. The prevention education of chronic diseases should be made through mass media as well as school education.

• 정신신체의학
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• 제24권1호
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• pp.9-19
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• 2016

어지럼을 호소하는 환자들 중 많은 환자에서 신경 이과적 검사에서는 이상이 없고 정신의학적으로 문제가 있는 경우가 있다. 이런 경우에 심인성 어지럼증이란 진단을 붙이는데, 이는 대개 정신의학적 문제로 인하여 어지럼이 발생한다. 어지럼증 환자의 2-4명 중 1명일 정도로 많은 편이다. 그러나 한국에서는 심인성 어지럼에 대한 진료, 연구 등이 부족한 편이다. 이에 저자는 한국 정신건강의학과 의사들이 심인성 어지럼에 대하여 많은 관심을 가지고 적극적인 동참을 하도록 하기위하여 이 논문을 발표하였다. 이 논문은 정신질환 특히 불안과 어지럼의 생물학적, 심리적 연관성을 포함한 심인성 어지럼의 원인 및 진단, 심인성 어지럼과 관련된 정신질환 및 각 정신질환에서의 어지럼의 특성, 그리고 심인성 어지럼의 치료에 대하여 고찰하였다. 또한 정신건강의학과 의사를 대상으로 하였기에 신경 이과와의 협진에 필수적인 중추성 및 말초성 어지럼에 대해서도 간략히 고찰하였다. 치료에서는 특정치료, 증상치료, 전정재활치료 뿐만이 아니라 심인성 어지럼의 치료에 필수적인 약물치료 및 인지행동치료에 대해서도 고찰하였다. 어지럼 환자에게 신경 이과적 검사 및 진료 시 기질적 문제가 없거나, 기질적 문제가 있을지라도 다른 정신과적 증상이 상당히 동반된 심인성 어지럼 환자라면 정신의학적 치료를 적용하여 치료성공률을 높이고 나은 귀결을 보일 것이다. 어지럼의 치료에는 다학제적 접근을 통한 환자-중심의 치료적 접근이 환자들의 고통 경감과 삶의 질의 향상을 도모할 수 있다. 이를 위해서 한국 정신건강의학과 의사들의 심인성 어지럼증에 대한 관심 증가 및 적극적인 참여가 필요하다고 제시한다.

• 한국전기전자재료학회논문지
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• 제34권6호
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• pp.495-504
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• 2021

Energy Harvesting is a technology that can convert wasted energy such as vibration, heat, light, electromagnetic energy, etc. into usable electrical energy. Among them, vibration-based piezoelectric energy harvesting (PEH) has high energy conversion efficiency with a small volume; thus, it is expected to be used in various autonomous powering devices, such as implantable medical devices, wearable devices, and energy harvesting from road or automobiles. In this study, wasted vibration energy in an automobile is converted into electrical energy by high-power piezoelectric materials, and the generated electrical energy is found to be an auxiliary power source for the operation of wireless sensor nodes, LEDs, etc. inside an automobile. In order to properly install the PEH in an automobile, vibration characteristics includes frequency and amplitude at several positions in the automobile is monitored initially and the cantilever structured PEH was designed accordingly. The harvesting properties of fabricated PEH is characterized and installed into the engine part of the automobile, where the vibration amplitude is stable and strong. The feasibility of PEH is confirmed by operating electric components (LEDs) that can be used in practice.

• The Korean journal of internal medicine
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• 제33권6호
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• pp.1111-1118
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• 2018

Background/Aims: Chest pain is an essential symptom in the diagnosis of acute coronary syndrome (ACS). One-third of patients with ACS present atypically, which can influence their receiving timely lifesaving therapy. Methods: A total of 617 NSTEMI patients from the Korea Acute MI Registry (KAMIR) and the Korea Working Group on MI (KorMI) databases were analyzed. The study population was divided into two groups by symptoms at presentation (typical symptoms group, 128; atypical symptoms groups, 128). Results: In this study population, 23% of patients presented without chest pain. After propensity score matching, the contact-to-device time ($2,618{\pm}381minutes$ vs. $1,739{\pm}241minutes$, p = 0.050), the symptoms-to-balloon time ($3,426{\pm}389minutes$ vs. $2,366{\pm}255minutes$, p = 0.024), and the door-to-balloon time ($2,339{\pm}380minutes$ vs. $1,544{\pm}244minutes$, p = 0.002) were significantly higher in the patients with atypical symptoms than in those with typical symptoms, respectively. Atypical symptoms were an independent predictor for 1-year mortality (hazard ratio, 2.820; 95% confidence interval, 1.058 to 7.515; p = 0.038). The Kaplan-Meier estimates showed higher risk for 12-month mortality in patients with atypical symptoms (p = 0.048) and no significant difference for 12-month major adverse cardiac events (p = 0.487). Conclusions: Acute myocardial infarction patients with atypical symptoms were not rare in clinical practice and showed a high risk of delayed reperfusion therapy. After imbalance between the groups was minimized by use of propensity score matching, patients who presented atypically had a high mortality rate.

• 대한임상독성학회지
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• 제17권1호
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• pp.38-41
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• 2019

Procalcitonin (PCT) is commonly employed in medical practice as a diagnostic biomarker of bacterial infection and also as a monitoring biomarker for antimicrobial therapy. There have been a few published reports concerning elevated PCT levels in people with acute liver injury caused by an overdose of acetaminophen. We report here on a case of PCT elevation in an adolescent with acute acetaminophen poisoning without any bacterial infection or liver injury. A 15-year-old girl had deliberately ingested 20 tablets of 650 mg acetaminophen (13 g) and she presented to our emergency department. The PCT level on admission was elevated to 65.64 ng/mL (reference range: 0-0.5 ng/mL). Her PCT level on the second day peaked up to 100 ng/mL and then it gradually decreased. There was no evidence of liver injury or infection on the computed tomography examination and other lab tests. The patient regained her good health and was discharged on the sixth day of hospitalization.

• 한국차세대컴퓨팅학회논문지
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• 제15권5호
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• pp.64-74
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• 2019

비강체 정합은 임상적 필요성은 높으나 계산 복잡도가 높고, 정합의 정확성 및 강건성을 확보하기 어려운 분야이다. 본 논문은 비지도 학습 환경에서 3차원 뇌 자기공명 영상 데이터에 딥러닝 네트워크를 이용한 비강체 정합 기법을 제안한다. 서로 다른 환자의 두 영상을 입력받아 네트워크를 통하여 두 영상 간의 특징 벡터를 생성하고, 변위 벡터장을 만들어 기준 영상에 맞추어 다른 쪽 영상을 변형시킨다. 네트워크는 U-Net 형태를 기반으로 설계하여 정합 시 두 영상의 전역적, 지역적인 차이를 모두 고려한 특징 벡터를 만들 수 있고, 손실함수에 균일화 항을 추가하여 3차원 선형보간법 적용 후에 실제 뇌의 움직임과 유사한 변형 결과를 얻을 수 있다. 본 방법은 비지도 학습을 통해 임의의 두 영상만을 입력으로 받아 단일 패스 변형으로 비강체 정합을 수행한다. 이는 반복적인 최적화 과정을 거치는 비학습 기반의 정합 방법들보다 빠르게 수행할 수 있다. 실험은 50명의 뇌를 촬영한 3차원 자기공명 영상을 가지고 수행하였고, 정합 전·후의 Dice Similarity Coefficient 측정 결과 평균 0.690으로 정합 전과 비교하여 약 16% 정도의 유사도 향상을 확인하였다. 또한, 비학습 기반 방법과 비교하여 유사한 성능을 보여주면서 약 10,000배 정도의 속도 향상을 보여주었다. 제안 기법은 다양한 종류의 의료 영상 데이터의 비강체 정합에 활용이 가능하다.

• 한국응용과학기술학회지
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• 제37권6호
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• pp.1659-1668
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• 2020

본 연구의 목적은 코로나-19 확산 속에서 손 씻기 교육 프로그램 적용이 지적장애 아동들의 손 씻기 빈도와 방법에 미치는 영향을 분석하는데 있다. 연구대상은 지적장애 아동 14명이며, 시각적 영상 자료를 활용한 손 씻기 교육에 참여하였다. 손 씻기 교육 프로그램은 소개, 이론교육, 실습으로 구성되었으며, 매주 2회로 16회기, 총 8주간 실시하였다. 손 씻기 이론교육은 손 씻기 중요성과 적응증, 올바른 손 씻기 단계와 방법, 손 씻기 도구 사용방법, 그리고 손 소독제 특성을 포함한 손 소독제 사용방법, 손 씻기로 인한 피부 손상 예방으로 구성되었다. 손 씻기 평가는 손 씻기 빈도와 방법 관찰 기록지를 활용하여 실시되었다. 손 씻기 빈도는 일상생활의 일과 중에서 손을 씻는 빈도를 평가하였으며, 일별, 월별 빈도를 분석하였다. 손 씻는 방법은 손 씻는 도구사용, 시간, 부위, 손 씻은 후 건조방법으로 구분하여 평가하였다. 그 결과 손 씻기 교육 프로그램 적용 후 대상자들의 손 씻는 빈도가 증가하였고, 손 씻는 방법도 향상되었다. 코로나-19 확산 속에서 적극적인 감염예방 방법으로 손 씻기는 매우 중요하다. 따라서, 본 연구결과를 토대로, 지적장애 아동들의 손 씻기 빈도를 증가시키고, 손 씻기 방법을 향상시키기 위해서 손 씩기 교육의 적용을 고려해야 할 것이다.

• 대한통합의학회지
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• 제10권1호
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• pp.157-168
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• 2022

Purpose : The purpose of this study is to determine the effect of the overseas volunteer activities of university students on changes in global citizenship. Methods : This study was conducted as a one-group pre-posttest design. The study's subjects were students who participated in the 37th World Friends Korea Youth Volunteer Corps in 2018. Among them, 158 students who completed the survey were included in the analysis. The tool for measuring global citizenship was comprised of knowledge, skill, attitude, and willingness to practice. The data were analyzed using the SPSS 26.0 program, and the statistical significance was set to p<.05. Results : Among the study's participants, there were 123 females (77.85 %). By grade, there were the most juniors, with 68 (43.04 %). There were 53 (33.55 %) seniors, 28 (18.35 %) sophomores, and eight freshmen (5.06 %). Among all participants, 52.53 % had experience in global citizenship education, and 63.92 % had experience in activities related to global citizenship. Because of analyzing the changes in global citizenship before and after overseas volunteer activities, "skill" increased the most, from 3.51±.65 points to 4.34±.56 points (p< .001). Due to analyzing changes in global citizenship before and after overseas volunteerism, the knowledge and attitude of freshmen were statistically significantly positive, with 1.17± 1.23 (p=.011) and 1.41±1.22 (p=.008), respectively. Participants with global citizenship experience had a significant change in attitude (p=.018). Conclusion : It was confirmed that the overseas volunteer activities of undergraduate students in the university brought a positive change to global citizenship. Providing opportunities for global citizenship education and activities in elementary, middle, and high schools in the future will maximize the effects of overseas volunteer activities to improve global citizenship.

• Nutrition Research and Practice
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• 제16권sup1호
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• pp.113-125
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• 2022

In the current years, it has now become necessary to establish standards for micronutrient intake based on scientific evidence. This review discusses issues related to the development of the 2020 Dietary Reference Intakes for Koreans (KDRI) for magnesium (Mg), zinc (Zn), and copper (Cu), and future research directions. Following issues were encountered when establishing the KDRI for these minerals. First, characteristics of Korean subjects need to be applied to estimate nutrient requirements. When calculating the estimated average requirement (EAR), the KDRI used the results of balance studies for Mg absorption and factorial analysis for Zn, which is defined as the minimum amount to offset endogenous losses for Zn and Mg. For Cu, a combination of indicators, such as depletion/repletion studies, were applied, wherein all reference values were based on data obtained from other countries. Second, there was a limitation in that it was difficult to determine whether reference values of Mg, Zn, and Cu intakes in the 2020 KDRI were achievable. This might be due to the lack of representative previous studies on intakes of these nutrients, and an insufficient database for Mg, Zn, and Cu contents in foods. This lack of database for mineral content in food poses a problem when evaluating the appropriateness of intake. Third, data was insufficient to assess the adequacy of Mg, Zn, and Cu intakes from supplements when calculating reference values, considering the rise in both demand and intake of mineral supplements. Mg is more likely to be consumed as a multi-nutrient supplement in combination with other minerals than as a single supplement. Moreover, Zn-Cu interactions in the body need to be considered when determining the reference intake values of Zn and Cu. It is recommended to discuss these issues present in the 2020 KDRI development for Mg, Zn, and Cu intakes in a systematic way, and to find relevant solutions.