Journal of The Korean Society of Clinical Toxicology (대한임상독성학회지)

Korean society of Clincal Toxicology (대한임상독성학회)
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Elevation of Procalcitonin in an Adolescent Acetaminophen Intoxication

아세트아미노펜 중독 청소년에서의 프로칼시토닌 상승

  • Kim, So Eun (Department of Emergency Medicine, Research Institute of Clinical Medicine of Chonbuk National University and Biomedical Research Institue of Chonbuk National University Hospital) ;
  • Lee, Jae Baek (Department of Emergency Medicine, Research Institute of Clinical Medicine of Chonbuk National University and Biomedical Research Institue of Chonbuk National University Hospital) ;
  • Jin, Young Ho (Department of Emergency Medicine, Research Institute of Clinical Medicine of Chonbuk National University and Biomedical Research Institue of Chonbuk National University Hospital) ;
  • Yoon, Jae Chol (Department of Emergency Medicine, Research Institute of Clinical Medicine of Chonbuk National University and Biomedical Research Institue of Chonbuk National University Hospital) ;
  • Jo, Si On (Department of Emergency Medicine, Research Institute of Clinical Medicine of Chonbuk National University and Biomedical Research Institue of Chonbuk National University Hospital) ;
  • Jeong, Tae Oh (Department of Emergency Medicine, Research Institute of Clinical Medicine of Chonbuk National University and Biomedical Research Institue of Chonbuk National University Hospital)
  • 김소은 (전북대학교 의학전문대학원 응급의학교실 및 전북대학교 임상의학 연구소/전북대학교병원 의생명 연구원) ;
  • 이재백 (전북대학교 의학전문대학원 응급의학교실 및 전북대학교 임상의학 연구소/전북대학교병원 의생명 연구원) ;
  • 진영호 (전북대학교 의학전문대학원 응급의학교실 및 전북대학교 임상의학 연구소/전북대학교병원 의생명 연구원) ;
  • 윤재철 (전북대학교 의학전문대학원 응급의학교실 및 전북대학교 임상의학 연구소/전북대학교병원 의생명 연구원) ;
  • 조시온 (전북대학교 의학전문대학원 응급의학교실 및 전북대학교 임상의학 연구소/전북대학교병원 의생명 연구원) ;
  • 정태오 (전북대학교 의학전문대학원 응급의학교실 및 전북대학교 임상의학 연구소/전북대학교병원 의생명 연구원)
  • Received : 2019.03.25
  • Accepted : 2019.06.22
  • Published : 2019.06.30
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Abstract

Procalcitonin (PCT) is commonly employed in medical practice as a diagnostic biomarker of bacterial infection and also as a monitoring biomarker for antimicrobial therapy. There have been a few published reports concerning elevated PCT levels in people with acute liver injury caused by an overdose of acetaminophen. We report here on a case of PCT elevation in an adolescent with acute acetaminophen poisoning without any bacterial infection or liver injury. A 15-year-old girl had deliberately ingested 20 tablets of 650 mg acetaminophen (13 g) and she presented to our emergency department. The PCT level on admission was elevated to 65.64 ng/mL (reference range: 0-0.5 ng/mL). Her PCT level on the second day peaked up to 100 ng/mL and then it gradually decreased. There was no evidence of liver injury or infection on the computed tomography examination and other lab tests. The patient regained her good health and was discharged on the sixth day of hospitalization.

Keywords

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