• Journal of Korean Neurosurgical Society
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• v.64 no.4
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• pp.562-574
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• 2021

Objective : This study is to evaluate the efficacy and safety of demineralized bone matrix (DBM) gel versus DBM gel with recombinant human bone morphogenetic protein-2 (rhBMP-2) used in transforaminal lumbar interbody fusion (TLIF). Methods : This study was designed as a prospective, multi-center, double-blind method, randomized study. All randomized subjects underwent TLIF with DBM gel with rhBMP-2 group (40 patients) as an experimental group or DBM gel group (36 patients) as a control group. Post-operative observations were performed at 12, 24, and 48 weeks. The spinal fusion rate on computed tomography scans and X-rays films, Visual analog scale pain scores, Oswestry disability index and SF-36 quality of life (QOL) scores were used for the efficacy evaluation. The incidence rate of adverse device effects (ADEs) and serious adverse device effects (SADEs) were used for safety evaluation. Results : The spinal fusion rate at 12 weeks for the DBM gel with rhBMP-2 group was higher with 73.68% compared to 58.82% for the DBM gel group. The 24 and 48 weeks were 72.22% and 82.86% for the DBM gel with rhBMP-2 group and 78.79% and 78.13%, respectively, for the DBM gel group. However, there were no significant differences between two groups in the spinal fusion rate at 12, 24, and 48 weeks post-treatment (p=0.1817, p=0.5272, p=0.6247). There was no significant difference between the two groups in the incidence rate of ADEs (p=0.3836). For ADEs in the experimental group, 'Pyrexia' (5.00%) was the most common ADE, followed by 'Hypesthesia', 'Paresthesia', 'Transient peripheral paralysis', 'Spondylitis' and 'Insomnia' (2.50%, respectively). ADEs reported in control group included 'Pyrexia', 'Chest discomfort', 'Pain', 'Osteoarthritis', 'Nephropathy toxic', 'Neurogenic bladder', 'Liver function analyses' and 'Urticaria' (2.86%, respectively). There was no significant difference between the two groups in the incidence rate of SADEs (p=0.6594). For SADE in the experimental group, ''Pyrexia' and 'Spondylitis' were 2.50%. SADE reported in the control group included 'Chest discomfort', 'Osteoarthritis' and 'Neurogenic bladder'. All SADEs described above were resolved after medical treatment. Conclusion : This study demonstrated that the spinal fusion rates of DBM gel group and DBM gel with rhBMP-2 group were not significantly different. But, this study provides knowledge regarding the earlier postoperative effect of rhBMP-2 containing DBM gel and also supports the idea that the longer term follow-up results are essential to confirm the safety and effectiveness.

• Journal of the Korea Institute of Information and Communication Engineering
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• v.19 no.6
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• pp.1353-1358
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• 2015

The creative economy is the industrialization era, the information age, knowledge-based economy, linking the new economic paradigm. The core words of the creative economy are stand for creativity, innovation, consumer protection and utilization of intellectual property. Creative ideas are combined with software technology will make innovative ecosystem-based structured market such as Apple, Google, Facebook. Intangible assets attributable to creativity than ever before in human history that is important as the economic value. In addition, innovative ideas, creativity and economic growth beyond the knowledge and information society is required. Because the core has a fusion of science and technology, industry, culture and industry convergence, various genres of creative activity support, and cultural and high-tech fusion industries, such as content creation and job creation through economic traction is needed. In this study, we analyze the case of the US Smithsonian Institution proposes the direction of Science Museum in creative workforce.

• Journal of the Korea Institute of Information and Communication Engineering
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• v.23 no.2
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• pp.193-200
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• 2019

The 2015 revised curriculum aims to cultivate a 'creative fusion talent' capable of creating new knowledge and fusing various knowledge to create new value. Therefore, it is strengthening reading education to raise humanistic imagination and software education to promote scientific creativity. In addition, we have created [Safe Living] textbooks based on experiential activities as a way to strengthen safety education that is becoming a social issue. And we use it to conduct safety education at creative activity time. Novel Engineering believes that it can develop thinking skills in the process of reading books and finding and solving problems in life in them. Therefore, in this study, we will develop software education programs for safety education that are applied with Novel Engineering and apply them to actual classes to verify the educational effectiveness of students' creative problem solving skills and safety education.

• Korean Journal of Construction Engineering and Management
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• v.25 no.2
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• pp.11-22
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• 2024

Power plant engineering industry obtains EPC plan project and delivers results about electricity, measurement, machinery, and piping and so on. Its works are taken by projects. Although power plant engineering composes 2~5% of whole EPC project cost, it's one of the fundamentals because it affects process after planning step a lot. However, domestic power plant engineering companies' project performance ability is insufficient and there's a need for systematic performance. Thus, this study defined related factors of successful performance and analyzed the priority among them through analytical hierarchy process. All respondents recognized experience, knowledge, and communication as important factors. Administrators considered knowledge, experience, and communication. But hands-on workers considered experience, knowledge, human resources. Those who have experience in oversea project considered process, experience, human resources. However those who don't have experience in oversea project considered knowledge, experience, and communication. Recognition of important factors varies by the position and work experience of members.

• Journal of KIISE
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• v.43 no.12
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• pp.1365-1375
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• 2016

One of the most important capabilities for autonomous service robots working in living environments is to recognize and understand the correct context in dynamically changing environment. To generate high-level context knowledge for decision-making from multiple sensory data streams, many technical problems such as multi-modal sensory data fusion, uncertainty handling, symbolic knowledge grounding, time dependency, dynamics, and time-constrained spatio-temporal reasoning should be solved. Considering these problems, this paper proposes an effective dynamic context management and spatio-temporal reasoning method for intelligent service robots. In order to guarantee efficient context management and reasoning, our algorithm was designed to generate low-level context knowledge reactively for every input sensory or perception data, while postponing high-level context knowledge generation until it was demanded by the decision-making module. When high-level context knowledge is demanded, it is derived through backward spatio-temporal reasoning. In experiments with Turtlebot using Kinect visual sensor, the dynamic context management and spatio-temporal reasoning system based on the proposed method showed high performance.

• Journal of Convergence for Information Technology
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• v.8 no.4
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• pp.181-188
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• 2018

The purpose of this study is to investigate the effect of multicultural competence on the organizational effectiveness of daycare teachers and to provide basic data to improve organizational effectiveness of daycare facilities. To achieve this goal, 258 childcare teachers attending C university were sampled for convenience and statistical processing was performed using PASW. First, there was a positive correlation between organizational productivity, organizational adaptability, and job satisfaction in the relationship between multicultural knowledge and organizational productivity, organizational adaptability, organizational commitment, and job satisfaction. second. The relationship between multicultural awareness and organizational productivity, organizational adaptability, and organizational commitment were all statistically correlated. Third, multicultural knowledge and multicultural awareness have positive effects on organizational commitment, organizational adaptability, and organizational productivity. Fourth, multicultural knowledge has a positive effect on job satisfaction. Therefore, in order to improve organizational effectiveness of day care facilities in the era of convergence, education programs related to multicultural knowledge and multicultural awareness are needed for daycare teachers.

• Journal of Institute of Control, Robotics and Systems
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• v.13 no.5
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• pp.434-443
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• 2007

Presently, the exploration of an unknown environment is an important task for thee new generation of mobile service robots and mobile robots are navigated by means of a number of methods, using navigating systems such as the sonar-sensing system or the visual-sensing system. To fully utilize the strengths of both the sonar and visual sensing systems. This paper presents a technique for localization of a mobile robot using fusion data of multi-ultrasonic sensors and vision system. The mobile robot is designed for operating in a well-structured environment that can be represented by planes, edges, comers and cylinders in the view of structural features. In the case of ultrasonic sensors, these features have the range information in the form of the arc of a circle that is generally named as RCD(Region of Constant Depth). Localization is the continual provision of a knowledge of position which is deduced from it's a priori position estimation. The environment of a robot is modeled into a two dimensional grid map. we defines a vision-based environment recognition, phisically-based sonar sensor model and employs an extended Kalman filter to estimate position of the robot. The performance and simplicity of the approach is demonstrated with the results produced by sets of experiments using a mobile robot.

• 한국지구물리탐사학회:학술대회논문집
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• 2003.11a
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• pp.21-26
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• 2003

The visualization of three dimensional geophysical data is forcing a revolution in the way of working, and allowing the discovery and production of hydrocarbons at much lower costs than previously thought possible. There are many aspects of this revolution that are behind the scenes, such as the database structure, the storage and retrieval of data, and the exchange of data among programs. Also the user had changes where the interpreter (or manager, or processor) actually looks at and somehow interacts with the data. The use of opacity in volume rendering, and how its judicious application can assist in imaging geologic features in three dimensional seismic data. This revolutionary development of new technology is based on the philosophy of synergy of inter-disciplines of the oil industry. Group interaction fostered by large room visualization environments enables the integration of disciplines we strive for, by putting the petrophysicist, geologist, geophysicist, and reservoir engineer in one place, looking at one image together, without jargon or geography separating them. All these tools developed in the oil industry can be applied into the civil engineering industry also such as the prior geological and geophysical survey of the constructions. Many examples will show how three dimensional geophysical technology might make a revolution in the oil business industry now and in future. This change can be considered as a fusion process at data, information, and knowledge levels.

• KSII Transactions on Internet and Information Systems (TIIS)
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• v.4 no.6
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• pp.1042-1062
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• 2010

Cooperative spectrum sensing (CSS) is an effective technology for alleviating the unreliability of local spectrum sensing due to fading/shadowing effects. Unlike most existing solutions, this paper considers the use of CSS technology in decentralized networks where a fusion center is not available. In such a decentralized network, some attackers may sneak into the ranks of cooperative users. On the basis of recent advances in bio-inspired consensus algorithms, an attack-proof, decentralized CSS scheme is proposed in which all secondary users can maintain cooperative sensing by exchanging information locally instead of requiring centralized control or data fusion. Users no longer need any prior knowledge of the network. To counter three potential categories of spectrum sensing data falsification (SSDF) attacks, some anti-attack strategies are applied to the iterative process of information exchange. This enables most authentic users to exclude potentially malicious users from their neighborhood. As represented by simulation results, the proposed scheme can generally ensure that most authentic users reach a consensus within the given number of iterations, and it also demonstrates much better robustness against different SSDF attacks than several existing schemes.

• Biomedical Science Letters
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• v.22 no.3
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• pp.107-114
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• 2016

Maintenance of fasting blood glucose levels is important for glucose homeostasis. Disruption of feedback mechanisms are a major reason for elevations of glucose level in blood, which is a risk factor for type 2 diabetes mellitus that is mainly caused by malfunction of pancreatic beta-cell and insulin. The fasting blood glucose level has been known to be influenced by genetic and environmental factors. Mitochondria have many functions for cell survival and death: glucose metabolism, fatty acid oxidation, ATP generation, reactive oxygen species (ROS) metabolism, calcium handling, and apoptosis regulation. In addition to these functions, mitochondria change their morphology dynamically in response to multiple signals resulting in fusion and fission. In this study, we aimed to examine association between fasting blood glucose levels and variants of the genes that are reported to have functions in mitochondrial dynamics, fusion and fission, using a cohort study. A total 416 SNPs from 36 mitochondrial dynamics genes were selected to analyze the quantitative association with fasting glucose level. Among the 416 SNPs, 4 SNPs of PRKACB, 13 SNPs of PPP3CA, 6 SNPs of PARK2, and 3 SNPs of GDAP1 were significantly associated. In this study, we were able to confirm an association of mitochondrial dynamics genes with glucose levels. To our knowledge our study is the first to identify specific SNPs related to fasting blood glucose level.