• Journal of the Korean Institute of Illuminating and Electrical Installation Engineers
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• v.27 no.10
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• pp.21-29
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• 2013

The short circuit and overload is presented by main cause of electrical fire. However, 85% of the fan directly connected the outlet box without switch in total 110 fans as a research in manufacturing industries. In installation direction of vertical type fans which was placed on the horizontal surface, only 39 vertical type fans were placed on vertical surface and 71 fans were placed on the horizontal type. The installation direction of the fans warns of the risk of the fire hazard due to the motor stall to the user manual of the maker. However, it is the representative nonconformity example of construction which the people or builder disregards. In addition, the condition of ground connection with the earth leakage prevention was investigated in grounding of 5 fans, non-grounding of 105 fans. The double insulation structure is generally used for small fan and it can't connect ground wire as electric plug of non-grounding type. However, industrial iron fan needs ground wire for electric leakage and to protect against electric shock.

• Advances in Traditional Medicine
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• v.6 no.3
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• pp.167-173
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• 2006

A growing body of evidence supports lipid peroxidation as having a role in the pathogenesis of liver disease. Although the probable cause of damage to human hepatocytes may be multifactorial, free radicals have been implicated in a variety of liver diseases, particularly in the presence of iron overload and toxic substances such as ethanol. Consequently, antioxidants, particularly those of plant origin such as flavonoids, may help to reduce the risk of developing these diseases. Silybum (S.) marianum, a medicinal plant widely used in traditional European medicine for the treatment of liver disorders, was evaluated for antioxidant activity. Thin layer chromatography and High Performance Liquid Chromatography analyses of crude extract of the plant confirmed the presence of a number of flavonoids reported in the literature. The antioxidant activity of these flavonoids was measured through inhibition of lipid peroxidation and 1, 1-diphenyl-2- picrylhydrazyl radical scavenging. The crude plant extract showed marked antioxidant activity in both assays. These results suggest that S. marianum contains flavonoids with antioxidant activity, capable of inhibiting or scavenging free radicals, thus supporting its traditional use as a hepatoprotective agent.

• Journal of IKEEE
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• v.22 no.3
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• pp.759-766
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• 2018

This paper presents a high-speed axial-flux machine which utilizes the idea of sinusoidal shaped pole combined with a consequent iron-pole. The target of the proposed machine is the cost reduction of the relatively expensive Samarium-Cobalt (SmCo) permanent magnet (PM) material and the torque per PM volume improvement by using sinusoidal consequent-pole rotor. The effectiveness of the proposed machine is validated by comparing it with conventional consequent-pole and with conventional PM machines using 3-D finite element method (FEM) simulations. The comparison and analysis is done in terms of back electro-motive force (back-EMF) harmonic contents, torque per PM volume and torque ripple characteristics. The simulation results show that the proposed machine is suitable and cost-effective for high-speed and high torque per PM volume applications. Furthermore, due to the consequent pole, the magnetic flux saturation and the overload current torque-capability are also presented and discussed in the paper.

• Journal of Yeungnam Medical Science
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• v.11 no.1
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• pp.82-93
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• 1994

Clinical study was carried out on the 64 hemodialysis patients(HD) with chronic renal failure who had been treated from December 1992 to July 1993 in Yeungnam University Hospital. The following results were obitained. In hematologic parameters, MCH was $28.8{\pm}2.0pg$, and MCV was $92.4{\pm}4.7fl$. Result revealed normochromic and normocytic anemia. Mean values of serum ferritin were $657.4{\pm}292.0ng/ml$ in men and $511.5{\pm}370g$ in women. Mean valuses of serum iron were $145.5{\pm}63.7{\mu}g/dl$. Mean values of transferrin saturation was $61.6{\pm}28.4%$. Serum frerritin, serum iron and transferrin saturation were higher in HD group than normal reference. In erythropoeitin treatment group, Hb and Hct were significantly higher than non-erythropoietin treatment group. Amount of transfusion was significantly higher in non-erythropoietin treatment group than erythropoeitin treatment group(p<0.05). Values of iron, transferrin saturation were significantly higher in abnormal liver function test(LFT) hemodialysis group than normal LFT group(p<0.05). Transfusion amounts revealed positive correlation with ferritin(r=0.4675), transferrin satruation (r=0.3823) and iron(r=0.3386)(p<0.05). In conclusion, erythropoietin treatment cna reduce requirement of blood transfusion and transfusion related side effects such as iron overload, hemosiderosis and hemochromatosis.

• Toxicological Research
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• v.23 no.3
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• pp.279-287
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• 2007

Copper (Cu) is an essential trace element indispensable for brain development and function; either excess or deficiency in Cu can cause brain malfunction. While it is known that Cu and Fe homeostasis are strictly regulated in the brain, the question as to how systemic Fe status may influence brain Cu distribution was poorly understood. This study was designed to test the hypothesis that dietary Fe condition affects Cu transport into the brain, leading to an altered brain distribution of Cu. Rats were divided into 3 groups; an Fe-deficient (Fe-D) group which received an Fe-D diet ($3{\sim}5 mg$ Fe/kg), a control group that was fed with normal diet (35mg Fe/kg), and an Fe-overload group whose diet contained an Fe-O diet (20g carbonyl Fe/kg). Following a 4-week treatment, the concentration of Cu/Fe in serum, CSF (cerebrospinal fluid) and brain were determined by AAS, and the uptake rates of Cu into choroids plexus (CP), CSF, brain capillary and parenchyma were determined by an in situ brain perfusion, followed by capillary depletion. In Fe-D and Fe-O, serum Fe level decreased by 91% (p<0.01) and increased by 131% (p<0.01), respectively, in comparison to controls. Fe concentrations in all brain regions tested (frontal cortex, striatum, hippocampus, mid brain, and cerebellum) were lower than those of controls in Fe-D rats (p<0.05), but not changed in Fe-O rats. In Fe-D animals, serum and CSF Cu were not affected, while brain Cu levels in all tested regions (frontal cortex, striatum, hippocampus, mid brain, and cerebellum) were significantly increased (p<0.05). Likewise, the unidirectional transport rate constants $(K_{in})$ of Cu in CP, CSF, brain capillary and parenchyma were significantly increased (p<0.05) in the Fe-D rats. In contrast, with Fe-O, serum, CSF and brain Cu concentrations were significantly decreased as compared to controls (p<0.05). Cu transport was no significant change of Cu transport of serum in Fe-O rats. The mRNA levels of five Cu-related transporters were not affected by Fe status except DMT1 in the CP, which was increased in Fe-D and decreased in Fe-O. Our data suggest that Cu transport into brain and ensuing brain Cu levels are regulated by systemic Fe status. Fe deficiency appears to augment Cu transport by brain barriers, leading to an accumulation of Cu in brain parenchyma.

• The Korean Journal of Community Living Science
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• v.13 no.2
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• pp.37-51
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• 2002

This study was performed to investigate the degree of different stresses and to search the influence of food habit and nutrient intakes at stress situation in university students and secondary school teachers. The data was collected by questionnaire method and searched nutrient intakes by 24 hours recall. The subjects were 282 students and 152 high school teacher in Kyunggi do. Physical status was no difference with two groups. Energy intake of teachers was lower than that of students, but the intakes of vitamin A and C were high in teachers' group. The university students had more stress situation than teachers in almost kind of stresses except overload stress. Self-diagnosed dietary habits were better in the group of teacher. Especially smoke and alcohol drink behavior were correlated with nutrient intakes in male teachers and students. The quantity of nutrient of nutrient intakes was correlated with different kind of stress. The stress of life event was correlated with the intakes of carbohydrate, minerals, thiamin and riboflavin, and the deprivation was with iron and vitamin A in teachers' group. The intake of almost nutrients was correlated with the stress of noise in students' group. By the analysis of stepwise multiple regression, although the $R^2$ values were very low, vitamin C intake was influenced in the factor at the stress of life events($R^2$=0.025), self-efface($R^2$=0.030) and noise($R^2$=0.020), thiamin was at food induced stress ($R^2$=0.021) and vitamin A was at the stress of type A behavior($R^2$=0.022) and anxiety response($R^2$=0.014). Therefore, we could concluded that different kind of stresses were influenced in dietary behavior and nutrient intakes. More research would be needed at the aspects of health promotion in the stressful situation of modern society.

• Clinical and Experimental Pediatrics
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• v.49 no.11
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• pp.1223-1226
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• 2006

Sideroblastic anemia is a rare, heterogeneous group of disorders characterized by hyperferremia, microcytic hypochromic anemia, and bone marrow erythroid hyperplasia with the presence of numerous ringed sideroblasts. We describe herewith the case of a rare coincidence of sideroblastic anemia and mitral valve prolapse with resultant regurgitation in a 2-year-old boy. In addition to the inherent propensity for the development of cardiac dysfunction in sideroblastic anemia due to transfusion-associated myocardial iron overload and chronic anemia, a coincidence of MVP will further increase the likelihood of the morbidity or mortality of th patient. in this patient. After response to pyridoxine, the patient remains in good condition with stable hemoglobin levels.

• Clinical and Experimental Pediatrics
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• v.63 no.8
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• pp.314-320
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• 2020

Background: The accumulation of unpaired α-globin chains in patients with β-thalassemia major may clinically create ineffective erythropoiesis, hemolysis, and chronic anemia. Multiple blood transfusions and iron overload cause cellular oxidative damage. However, α-tocopherol, an antioxidant, is a potent scavenger of lipid radicals in the membranes of red blood cells (RBCs) of patients with β-thalassemia major. Purpose: To evaluate the effects of α-tocopherol on hemolysis and oxidative stress markers on the RBC membranes of patients with β-thalassemia major. Methods: Forty subjects included in this randomized controlled trial were allocated to the placebo and α-tocopherol groups. Doses of α-tocopherol were based on Institute of Medicine recommendations: 4-8 years old, 200 mg/day; 9-13 years old, 400 mg/day; 14-18 years old, 600 mg/day. Hemolysis, oxidative stress, and antioxidant variables were evaluated before and after 4-week α-tocopherol or placebo treatment, performed before blood transfusions. Results: Significant enhancements in plasma haptoglobin were noted in the α-tocopherol group (3.01 mg/dL; range, 0.60-42.42 mg/dL; P=0.021). However, there was no significant intergroup difference in osmotic fragility test results; hemopexin, malondialdehyde, reduced glutathione (GSH), or oxidized glutathione (GSSG) levels; or GSH/GSSG ratio. Conclusion: Use of α-tocopherol could indirectly improve hemolysis and haptoglobin levels. However, it played no significant role in oxidative stress or as an endogen antioxidant marker in β-thalassemia major.