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Pyridoxine responsive sideroblastic anemia in a boy with mitral valve prolapse  

Sung, June Seung (Department of Pediatrics, Hwasun Chonnam National University Hospital Chonnam National University Medical School)
Kim, Ki Hwan (Department of Pediatrics, Hwasun Chonnam National University Hospital Chonnam National University Medical School)
Han, Dong Gyun (Department of Pediatrics, Hwasun Chonnam National University Hospital Chonnam National University Medical School)
Kim, Mi Jeong (Department of Pediatrics, Hwasun Chonnam National University Hospital Chonnam National University Medical School)
Cho, Young Kook (Department of Pediatrics, Hwasun Chonnam National University Hospital Chonnam National University Medical School)
Chung, Hae Yul (Department of Pediatrics, Hwasun Chonnam National University Hospital Chonnam National University Medical School)
Baek, Hee Jo (Department of Pediatrics, Hwasun Chonnam National University Hospital Chonnam National University Medical School)
Ma, Jae Sook (Department of Pediatrics, Hwasun Chonnam National University Hospital Chonnam National University Medical School)
Kook, Hoon (Department of Pediatrics, Hwasun Chonnam National University Hospital Chonnam National University Medical School)
Hwang, Tai Ju (Department of Pediatrics, Hwasun Chonnam National University Hospital Chonnam National University Medical School)
Publication Information
Clinical and Experimental Pediatrics / v.49, no.11, 2006 , pp. 1223-1226 More about this Journal
Abstract
Sideroblastic anemia is a rare, heterogeneous group of disorders characterized by hyperferremia, microcytic hypochromic anemia, and bone marrow erythroid hyperplasia with the presence of numerous ringed sideroblasts. We describe herewith the case of a rare coincidence of sideroblastic anemia and mitral valve prolapse with resultant regurgitation in a 2-year-old boy. In addition to the inherent propensity for the development of cardiac dysfunction in sideroblastic anemia due to transfusion-associated myocardial iron overload and chronic anemia, a coincidence of MVP will further increase the likelihood of the morbidity or mortality of th patient. in this patient. After response to pyridoxine, the patient remains in good condition with stable hemoglobin levels.
Keywords
Sideroblastic anemia; Pyridoxine; Mitral valve prolapse;
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