• Bulletin of the Korean Chemical Society
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• v.32 no.4
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• pp.1170-1178
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• 2011

In the present study, the approach of high accuracy mass measurements for phospholipid identifications was evaluated using a 7 T ESI-FTMS/linear ion trap MS/MS. Experiments were carried out for porcine brain, bovine liver, and soybean total lipid extracts in both positive and negative ion modes. In total, 59, 55, and 18 phospholipid species were characterized in the positive ion mode for porcine brain, bovine liver, and soybean lipid extracts, respectively. Assigned lipid classes were PC, PE, PEt, PS, and SM. In the negative ion mode, PG, PS, PA, PE, and PI classes were observed. In the negative ion mode, for porcine brain, bovine liver, and soybean lipid extracts, 28, 34, and 29 species were characterized, respectively. Comparison of our results with those obtained by other groups using derivatization-LC-APCI MS and nano-RP-LC-MS/MS showed that our approach can characterize PC species as effectively as those methods could. In conclusion, we demonstrated that high accuracy mass measurements of total lipid extracts using a high resolution FTMS, particularly, 7T FTMS, plus ion-trap MS/MS are very useful in profiling lipid compositions in biological samples.

• Journal of Sensor Science and Technology
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• v.22 no.2
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• pp.136-143
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• 2013

In the study, novel blood pressure estimation method was proposed to improve the accuracy of oscillometric method. The proposed algorithm estimated the blood pressure by comparing and analyzing the point variation aspect of dicrotic notch on pulsating waveform during each cardiac cycle. The waveforms of each cardiac cycle were extracted by maximum points. The extracted pulsating waveforms were applied by re-sampling, end-matching, and normalization. The systolic and diastolic blood pressures were estimated by point variation aspect of dicrotic notch. The blood pressures, which were estimated from proposed algorithm, were compared and analyzed by blood pressures from oscillometric methods and auscultation. The systolic blood pressure from oscillometric methods were +0.88 mmHg more than proposed algorithm, and 1.875 less than the diastolic blood pressures from proposed algorithm. The systolic and diastolic blood pressures from auscultation were 2.89 mmHg and 3.44 mmHg less than the blood pressures from proposed algorithm. As the errors between blood pressures from proposed algorithm, oscillometric method and auscultation were less than 5 mmHg, the proposed algorithm was effective.

• Genomics & Informatics
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• v.19 no.1
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• pp.11.1-11.8
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• 2021

For the novel coronavirus disease 2019 (COVID-19), predictive modeling, in the literature, uses broadly susceptible exposed infected recoverd (SEIR)/SIR, agent-based, curve-fitting models. Governments and legislative bodies rely on insights from prediction models to suggest new policies and to assess the effectiveness of enforced policies. Therefore, access to accurate outbreak prediction models is essential to obtain insights into the likely spread and consequences of infectious diseases. The objective of this study is to predict the future COVID-19 situation of Korea. Here, we employed 5 models for this analysis; SEIR, local linear regression (LLR), negative binomial (NB) regression, segment Poisson, deep-learning based long short-term memory models (LSTM) and tree based gradient boosting machine (GBM). After prediction, model performance comparison was evelauated using relative mean squared errors (RMSE) for two sets of train (January 20, 2020-December 31, 2020 and January 20, 2020-January 31, 2021) and testing data (January 1, 2021-February 28, 2021 and February 1, 2021-February 28, 2021) . Except for segmented Poisson model, the other models predicted a decline in the daily confirmed cases in the country for the coming future. RMSE values' comparison showed that LLR, GBM, SEIR, NB, and LSTM respectively, performed well in the forecasting of the pandemic situation of the country. A good understanding of the epidemic dynamics would greatly enhance the control and prevention of COVID-19 and other infectious diseases. Therefore, with increasing daily confirmed cases since this year, these results could help in the pandemic response by informing decisions about planning, resource allocation, and decision concerning social distancing policies.

• The Journal of the Society of Korean Medicine Diagnostics
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• v.10 no.1
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• pp.78-97
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• 2006

Background: There was seldom study about method that estimate expertness of pulse diagnosis in 8 Constitution Medicine in spite of the diagnostician importance in 8 Constitution Medicine Objectives: This study is to evaluate diagnostician's consistency and accuracy about pulse diagnosis in 8 Constitution Medicine using Cage R&R study. Methods: The subjects were comprised of 28 volunteers. Among theme, 3 diagnosticians and 10 participants were chosen through questionnaire. Diagnosticians diagnosed participant's Constitution by pulse diagnosis in 8 Constitution Medicine with hiding their eyes by eyepatch. MINITAB statistical software(ver. 13.20) was used for statistical analysis: Attribute Cage R&R study was used to verify the results. Results: 1. In the measurements of consistency, diagnostician b(agreement=80%, Value of k=0.8276)was very good, diagnostician a(agreement=70%, Value of k=0.7465) was good, and diagnostician c(agreement=50%, Value of k=0.5365) was moderate. 2. In the measurements of accuracy, diagnostician b(agreement =70%, Value of t=0.6812) was good, diagnostician a(agreement=60%. Value of t=0.6414) was good, and diagno-stician c(agreement=0%, Value of k=-0.1000) was poor. 3. In cofidence of diagnosis, diagnostician c was 75%, diagnostician a was 70%, and diagnostician b was 64%. Conclusion: The results suggest that diagnostician's consistency and accuracy about pulse diagnosis in 8 Constitution Medicine can be evaluated by Cage R&R study. further study is needed for estimation method of pulse diagnosis in 8 Constitution Medicine.

• Journal of Microbiology and Biotechnology
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• v.31 no.9
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• pp.1241-1255
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• 2021

This study was carried out to explore a non-chemical strategy for enhancing productivity by employing some antagonistic rhizobacteria. One hundred eighteen bacterial isolates were obtained from the rhizospheric zone of various crop fields of Gangwon-do, Korea, and screened for antifungal activity against Fusarium wilt (Fusarium oxysporum f. sp. lactucae) in lettuce crop under in vitro and in vivo conditions. In broth-based dual culture assay, fourteen bacterial isolates showed significant inhibition of mycelial growth of F. oxysporium f. sp. lactucae. All of the antagonistic isolates were further characterized for the antagonistic traits under in vitro conditions. The isolates were identified on the basis of biochemical characteristics and confirmed at their species level by 16S rRNA gene sequencing analysis. Arthrobacter sulfonivorans, Bacillus siamensis, Bacillus amyloliquefaciens, Pseudomonas proteolytica, four Paenibacillus peoriae strains, and Bacillus subtilis were identified from the biochemical characterization and 16S rRNA gene sequencing analysis. The isolates EN21 and EN23 showed significant decrease in disease severity on lettuce compared to infected control and other bacterial treatments under greenhouse conditions. Two bacterial isolates, EN4 and EN21, were evaluated to assess their disease reduction and growth promotion in lettuce in field conditions. The consortium of EN4 and EN21 showed significant enhancement of growth on lettuce by suppressing disease caused by F. oxysporum f. sp. lactucae respectively. This study clearly indicates that the promising isolates, EN4 (P. proteolytica) and EN21 (Bacillus siamensis), can be commercialized and used as biofertilizer and/or biopesticide for sustainable crop production.

• The Journal of the Society of Korean Medicine Diagnostics
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• v.15 no.1
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• pp.29-46
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• 2011

Objectives: The purpose of our study is to develop and verify questionnaire using temperament and character inventory (TCI) in the future by contemplating the comparative study on TCI and psychological testing Questionnaires. Methods: We investigate the research searched by keyword: 'TCI' and 'Questionnaire' through internet search engines, Pub Med, Science Direct and Springer Link. Results: The comparative study of TCI and psychological testing Questionnaires(SPAQ, BDI, TAS-20, MAC, DSQ) which have the purpose of diagnosing personal disorder is helpful for the verification of the level of adequacy of the concerned psychological testing Questionnaire and contributes to the understanding of psychobiological characteristics of each of personal disorders. The comparative study of TCI and psychological testing Questionnaires(MMPI, NEO, CPI) which have the purpose of comprehending general personality is helpful for the verification of the level of adequacy of the concerned psychological testing Questionnaire and contributes to the understanding of meaning of questionnaire-scales. The comparative study of TCI and constitution-psychological testing Questionnaire(QSCC II) is helpful for the verification of the level of adequacy and the understanding of the concerned constitution-psychological testing Questionnaire and contributes to the understanding of psychobiological characteristics of each of constitutions. Conclusions: TCI is a useful tool to understand the psychological testing Questionnaire more deeply and verify the level of the adequacy, and from now on for the development and verification of Oriental medicinal-psychological testing Questionnaire, the study comparing it with TCI should be actively used.

• Progress in Medical Physics
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• v.22 no.4
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• pp.172-177
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• 2011

The purpose of this study was to analyze $^{68}Ga$-BAPEN dynamic PET image in rat myocardium to evaluate potential of this radiotracer as a perfusion imaging agent. Animal PET/CT scan was done in 9 rats during 120 minutes. Especially we synthesized $^{68}Ga$-BAPEN with kit which is simple and low cost method. PET images showed the in vivo dynamic distribution of $^{68}Ga$-BAPEN in the chest region of rats. Initially $^{68}Ga$-BAPEN PET images showed aorta and liver activities and a few minutes later, $^{68}Ga$-BAPEN moved to myocardium. Regions of interest were drawn on myocardium, liver, lung and blood pool. Time-activity curves showed significant uptake of $^{68}Ga$-BAPEN in myocardium. The contrast ratios of myocardial to blood pool, lung and liver at 60 minutes after injection were 1.66, 2.82 and 0.60. To estimate accurate kinetic parameters, 60 minutes after injection was required to PET scan as myocardium image contrast ratios reached to constant values. As a result, $^{68}Ga$-BAPEN would be suitable radiotracer for PET which can applied to diagnosis of myocardial perfusion diseases after further preclinical and clinical investigations.

• 대한공업교육학회지
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• v.41 no.2
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• pp.151-171
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• 2016

The purpose of this study is to verify the effect of Interdisciplinary course for improving the competency of collegiate Interpersonal & Cooperative Skills, Resources-Information-Technology Processing & Application and Communication. The course proved to be effective based on the result for examination of difference between the experimental group of 43 students who took the interdisciplinary course and the control group of 44 students who did not take that course of the second semester of H university in 2015. The study applied the method of Paired-sample T-Test to investigate the difference of Interpersonal & Cooperative Skills, Resources-Information-Technology Processing & Application and Communication and their sub-skills between the two participant groups. As a result, Interdisciplinary course had an effect on improvement of Interpersonal & Cooperative Skills and it's sub skills; however, it had no effect on improvement of Resources-Information-Technology Processing & Application and Communication competency and their sub-skills. The results provide theoretical and practical implications for the interdisciplinary course and core competence of college students. They suggest that interdisciplinary course design should be more careful to improve students' competency on Resources-Information-Technology Processing & Application and Communication competency than before.

• Journal of Contemporary Eastern Asia
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• v.23 no.1
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• pp.35-57
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• 2024

The overarching purpose of this study is to examine the current status of academic public engagement in Vietnam. Data were obtained from a survey with 245 university lecturers, and descriptive statistics were used jointly with Bayesian statistics as tools for analysis. This study reveals that a significant proportion of university lecturers are not involved in public engagement, neither through the public press (66.5%) nor social media (49%). Those who have been active in public engagement use the public press and social networks to communicate science, with the latter being more used than the former. In addition, this study also pointed out that experienced scientists tend to engage with the public press, while early-career researchers often choose social networks. The findings of this study provide implications for higher education policymakers and administrators.

• New & Renewable Energy
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• v.7 no.1
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• pp.36-44
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• 2011

Technology is developed from the efficient interaction with other technology files while building up its own research field. This study analyzes the structure of solar cell research area and describes its paths of the technology development in terms of interdisciplinary diversity using the Co-Classification method during 1979-2009. As a results, 1,380 studies are determined as the interdisciplinary among the 2,605 studies. It shows that 52.98% of the solar cell researches have interdisciplinary relationships with two or more research fields. In addition, we show that the research area of solar cell technology is composed by Material Science, Multidisciplinary and Energy & Fuel, Physics, Applied, Chemistry, Physical from the Co-Classification matrix and network analysis. It means the complexity of the technological knowledge production increased with the concept of interdisciplinary. The results can be used for the planning of the efficient solar cell technology development.