• 제목/요약/키워드: IV Regression

검색결과 245건 처리시간 0.028초

제 IV병기 비소세포폐암의 예후인자 (Prognostic Factors for Survival in Patients with Stage IV non-small Cell Lung Cancer)

  • 김명훈;박희선;강현모;장필순;이연선;안진영;권선중;정성수;김주옥;김선영
    • Tuberculosis and Respiratory Diseases
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    • 제53권4호
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    • pp.379-388
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    • 2002
  • 연구배경 : 폐암 중 80%를 차지하는 비소세포폐암은 발견 당시부터 전이성 병변이 있는 IV기로 진단되는 경우가 적지 않다. 그러나 그동안 IV병기 비소세포폐암의 예후인자에 대한 조사는 충분하지 않았었다. 이에 저자들은 IV병기 비소세포폐암으로 진단을 받은 환자들을 대상으로 생존기간에 영향을 미치는 예후인자의 분석과 M1으로 평가되는 전이 장기에 따른 생존기간의 차이를 조사하고자 하였다. 방 법 : 1997년 1월부터 2000년 12월까지 충남대학교병원에 내원해서 병리조직학적으로 IV병기 비소세포폐 암으로 진단을 받은 151명을 대상으로 하였고, 의무기록을 통한 후향적인 방법으로 분석하였다. 결 과 : 1) 생존기간에 대한 단변수 분석 결과 연령, 신체 활동도, 혈청 알부민 농도, 체중감소, $FEV_1$, 전신 항암화학요법 유무, 전이 장기 개수는 생존기간에 매우 유의한 (p<0.01) 예후인자들이었으며, 혈청 LDH 농도 역시 유의한 예후인자이었다 (p<0.05). 2) 전이 장기에 따른 생존율의 단변수 분석에서 뇌전이, 간전이가 있는 경우가 그 외에 다른 장기에 전이가 있는 경우보다 생존율이 낮았다 (p<0.05). 3) 단독으로 전이된 장기에 따른 생존율의 분석에서 폐전이만 있는 경우가 폐와 다른 장기의 전이가 동시에 있는 경우나 폐 이외의 장기에 전이가 있는 경우보다 생존율이 높았다 (p=0.000). 4) 생존기간에 대한 다변수 분석 결과 ECOG (상대위험도=2.700, p=0.000), 전신 항암화학요법 유무 (상대위험도=1.944, p=0.010), 혈청 LDH 농도(상대위험도=1.819, p=0.021) 그리고 $FEV_1$ (상대위험도=1.774, p=0.022)이 생존기간에 영향을 미치는 유의한 독립적인 예후인자였다. 결 론 : 본 연구에서 IV병기 비소세포폐암 중 폐에 단독으로 전이가 있는 경우가 다른 장기에 전이가 있는 경우보다 비교적 생존율이 높았고, 뇌전이, 간전이가 있는 경우 생존율이 낮았다. 따라서 원격전이로 동일하게 평가되고 있는 M1 병기라도 전이 장기의 종류에 따라 생존기간의 차이가 있을 수 있으므로 M1 병기 시스템에서 생존율에 대하여 재해석이 고려되어야겠다. 그러나 이번 연구는 후향적 분석이며 대상환자수가 많지 않아서 이 결과에 대한 확인을 위해서 이후에 많은 수의 환자를 대상으로 전향적인 연구가 필요하다고 생각된다.

전국 보건소 물리치료실 운영 실태와 활성화 방안 (Improving Physical Therapy Services of Health Centers in Korea)

  • 장은주
    • 대한물리치료과학회지
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    • 제3권2호
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    • pp.1021-1036
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    • 1996
  • The purpose of this study are ( i ) to examine operating situation of physical therapy department and job satisfaction of physical therapists in health centers, (ii) to analyze utilization patterns and patient satisfaction of physical therapy services among health center visitors, and finally, (iii) to suggest policy implications in facilitating improvement on physical therapy services of health centers. The materials are collected from 105 physical therapists among nationwide health centers and 203 patients of 5 health centers in Pusan, Korea. The survey is conducted from February 13 to March 30, 1996 with a structured self - administered questionnaire. Major results of the study are as follows. First, the result of regression analysis between job satisfaction and affecting factors identify following variables as the significant determinants; self-development(+), job itself(+), and co-worker support (+). Second, the current operating situation of physical therapy department shows such problem as; i )shortage and unstable job security of physical therapists, ii )absence of rehabilitation specialist, iii )lack of understanding on physical therapy of co-workers, iv)shortage of physical therapy equipment and facility, v)burdensome task of physical therapists, and vi) inappropriate purchase process of equipment. Third, patient satisfaction for physical therapy services are revealed relatively high. And the result of regression analysis between patient satisfaction and affecting factors identify following variables as the significant determinants; credibility of physical therapist(+), satisfaction for waiting time(+), cleanliness(+). Fourth, the patients appeal about physical therapy services such problem as; i) shortage of physical therapists, physical therapy equipment, and facility, ii) inconvenient administrative procedure for utilization physical therapy services. Fifth and last, recommendations for the improvement of physical therapy services of health centers are as follows; i )recruiting more physical therapists, ii )regular employment of physical therapists instead of daily use employment, iii )re-arrangement of facility for patient's convenience, iv )establishing reasonable purchasing system of equipment for physical therapy, v) reforming administrative procedure for patient focused care.

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랜드마크의 영향력 범위와 인지요인과의 관계 (A Study on the Relationship between Influential Range and Cognition Factor of Landmark)

  • 김종호;변재상;임승빈
    • 한국조경학회지
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    • 제30권4호
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    • pp.9-18
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    • 2002
  • This study investigated the influential range of landmarks and the relationship between landmarks and cognition factor so as to offer basic data to be used for the effective use and the management of landmarks. In this study, eighteen famous landmark in Seoul were selected and analyzed. The result of this study can be summarized as follows : 1) First, eighteen determining elements of cognition factors were selected via documents survey. Second, general cognition factors of landmarks were analysed using these elements through questionnaires to specialists. As a result of factor analysis, historic cultural factor, scale factor, visual form factor, locational factor and uniqueness factor were revealed. 2) According to revealed cognition factor, eighteen landmarks are categorized into four types using MDS method via questionnaire to resident in Seoul city. These four types of landmarks are: type I that are recognized by historic cultural factor; type II that are recognized by scale factor; type III that are recognized by uniqueness factor; and type IV that are recognized by visual form factor. 3) As the result of regression, the influential range of landmarks were revealed at about a 10km radius(type I : 12km type II : whole area of Seoul city≒15km, typeIII : 8.7km, typeIV : 8.5km). 4) As a result of analysing the correlation between the influential range and the cognition factor through multiple linear regression analysis, the locational factor is the main factor affecting the influential range of landmarks in every type. The uniqueness factor comes next, which affects influential range partially. 5) Except type 1, as a result of analysing the correlation between influential range and the physical heights of landmarks, a quadratic equation is revealed, showing that the influential range of landmarks over 200 meters in height shows a radical change. Landmarks can be used as reinforcement tools of legibility, effective tools for landscape management and for the improvement of a community's image. This study on the influential range of landmarks and main cognition factor can be utilized as a landmark management plan and in urban planning, such as a new town plan.

알콜중독자의 우울이 자살사고(思考)에 미치는 영향 -사회적 지지의 매개효과- (The Effect of Alcoholics' Depression on Suicidal Ideation -The Mediating Effect of Social Support-)

  • 이은희
    • 디지털융복합연구
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    • 제17권2호
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    • pp.423-431
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    • 2019
  • 본 연구의 목적은 알코올 중독자의 우울과 자살사고의 관계에서 사회적 지지의 매개역할을 규명하는 것이다. 본 연구의 연구대상자들은 DSM-IV의 기준에 의하여 알코올 의존으로 진단받은 성인들로, 현재 알코올중독치료를 위해 울산, 부산, 포항, 경주지역에 위치한 병원에서 입원 치료중인 사람들이다. 설문조사는 대상자들에게 본 연구의 목적을 설명한 후 설문조사에 동의한 사람들에게 설문지를 배포하여 자기 기입방법으로 실시했다. 이러한 과정을 통해 217부의 설문지가 분석되었다. 조사기간은 2017년 10월 01일부터 11월 01일 사이에 이루어졌다. 알코올 중독자들의 우울이 자살사고에 미치는 영향에서 사회적 지지의 매개효과를 검증하기 위해서는 3단계 매개 회귀분석과 Sobel test를 실시하였다. 연구결과, 알코올 중독자들의 우울이 자살사고에 미치는 영향에서 사회적 지지의 부분 매개효과가 검증되었다. 이러한 연구결과에 근거하여 알코올 중독자들에 대한 사회적 지지 강화를 위한 개입전략을 제안하였다.

경도인지장애에서 우울증 유병률과 관련요인 (Prevalence and Associated Factors of Depression in Mild Cognitive Impairment)

  • 이준호;최영민;변민수;최효정;백혜원;손보경;이동영
    • 노인정신의학
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    • 제18권2호
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    • pp.86-91
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    • 2014
  • Objective : The aims of this study were to investigate the prevalence of co-morbid depression and related factors of depression in mild cognitive impairment (MCI) patients. Methods : Nine hundred and six MCI individuals were included in this study. Depression was defined as major and minor depressive disorder according to the Diagnostic and Statistical Manual of Mental Disorders, fourth edition (DSM-IV). Depression-related demographic and clinical factors were also explored through multivariate logistic regression analysis. Results : In MCI patients, the prevalence of depression as defined according to the DSM-IV diagnostic criteria was 1.8% for major depressive disorder, 11.4% for minor depressive disorder, and overall 13.2% for both. Multivariate logistic regression showed that increased prevalence of overall depression was associated with female gender and non-amnestic subtype of MCI. Conclusion : Our findings based on a large number of MCI subjects who visited memory clinic indicated that more than ten percent of MCI patients have comorbid depression. In addition, female and non-amnestic subtype of MCI patients seems to be more vulnerable to depression.

한약에 의한 진행성 위선암의 퇴축에 대한 증례보고 - 8년간의 추적조사를 통한 후향적 증례연구 (A Case of Regression of Advanced Gastric Cancer by Herbal Medicine - A Retrospective Case Study with 8-years Follow-up)

  • 박정석;이연월;조정효;손창규;조종관;유화승
    • 대한한방내과학회지
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    • 제28권1호
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    • pp.193-198
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    • 2007
  • Objective : The aim is to derive further studies evaluating the effectiveness of oriental medical treatment on advanced gastric cancer (AGC) patients. We present a case of a stage IV AGC patient who has survived over 8 years. Methods : We followed up all documents related to the patient. We prescribed to the patient HangAmDan (HAD) three times a day over five years. Abdomen CT was performed to evaluate the therapeutic efficacy. Results : The patient has survived over 8 years. Abdomen CT has shown complete regression. Conclusion : This case may give us the possibility of that oriental medical treatment offers potential benefits for patients with AGC.

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자격증이 임금, 노동이동에 미치는 효과: 기능사 2급 자격증을 중심으로 (Analysis of Certification Effects on Wage and Labor Mobility : Evidence from Craft II Class Certification)

  • 이상준
    • 노동경제논집
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    • 제29권2호
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    • pp.145-169
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    • 2006
  • 이 연구는 국가기술자격증 중 기능사 2급 자격 등급을 이용하여 자격증의 임금, 노동이동 효과에 대한 실증분석을 하고 있다. 이를 위해 모수적 방법과 비모수적 방법을 사용한다. 모수적 방법에서는 자격증의 선택 문제를 해결하고자 직종별 사업장 규모별 자격증 비율을 IV로 사용하였으며 비모수적 방법에는 페어메칭을 이용하였다. 간략한 연구 결과를 살펴보면 자격증이 임금에 미치는 효과는 작게는 5.5%에서 많게는 9.9% 가량 존재하고 있다. 자격증과 노동이동 간의 관계에서는 실제 노동이동을 통한 자격증의 임금효과보다는 한 직장에 근속함으로써 얻는 임금효과가 크게 나타나고 있음을 알 수 있다. 또한 자격증이 없는 근로자들일수록 상대적으로 동일 사업장에 정착하기가 어렵다는 것을 알 수 있었다.

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20대 남성의 실제체형과 신체이상형(理想型)에 관한 연구 (A Study on Real Body Size and Ideal Body Shape of 18 to 25 Year-Old Men)

  • 정재은;이순원
    • 대한인간공학회지
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    • 제17권2호
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    • pp.49-63
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    • 1998
  • The purpose of this study is to study real body size and ideal body shape by considering the degree of satisfaction of body part and understanding body size by the degree of leanness/obesity. The subjects in this study were 420 males from 18 to 25 years old. Body measurements and surveys were taken and analyzed by mean, standard variation, correlation analysis, regression analysis, crosstabulation analysis, cluster analysis, one-way ANOVA, and Duncan's Test. The results of analyses indicate that the subjects tended to be satisfied with thick chest and upper limbs, wide shoulder width, and preferred to be tall and have big hands and feet. By cluster analysis of 19 variables, the subjects were divided into 4 groups, each consisting 41, 138, 134, and 47 males. Because the 19 variables were body measurements transformed to eliminate the body size factor, this classification was considered to express how lean or how obese a human body appears. The results of one way ANOVA and Duncan's Test indicate that, according to the degree of leanness/obesity from Group I (lean tendency) to Group IV(obese tendency), characteristics of the body shape changed as follows; height became lower, limbs became shorter, trunk and limbs became thicker and weight became heavier. Also it showed that Group IV were most satisfied with chest girth, upper limb girth and shoulder width and Group I with height, hip girth and waist girth.

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Risk Factors of the 2-Year Mortality after Bipolar Hemiarthroplasty for Displaced Femoral Neck Fracture

  • Jung Wook Huh;Han Eol Seo;Dong Ha Lee;Jae Heung Yoo
    • Hip & pelvis
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    • 제35권3호
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    • pp.164-174
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    • 2023
  • Purpose: This study investigates the relationship between preoperative neutrophil-to-lymphocyte ratio (NLR), lymphocyte-to-C-reactive protein ratio (LCR), albumin, and 2-year mortality in elderly patients having hemiarthroplasty for displaced femoral neck fracture (FNF). Materials and Methods: We retrospectively reviewed 284 elderly patients who underwent hemiarthroplasty for Garden type IV FNF from September 2014 to September 2020. Using the receiver operating characteristic curve, optimal cutoff values for LCR, NLR, and albumin were established, and patients were categorized as low or high. Associations with 2-year mortality were evaluated through univariate and multivariate Cox regression analyses. Results: Of the 284 patients, 124 patients (45.9%) died within 2 years post-surgery. The optimal cutoff values were: LCR at 7.758 (specificity 58.5%, sensitivity 25.0%), NLR at 3.854 (specificity 39.2%, sensitivity 40.0%), and albumin at 3.750 (specificity 65.9%, sensitivity 21.9%). Patients with low LCR (<7.758), high NLR (≥3.854), and low albumin (<3.750) had a statistically significant reduced survival time compared to their counterparts. Conclusion: Lower preoperative LCR and albumin levels, along with higher NLR, effectively predict 2-year mortality and 30-day post-surgery complications in elderly patients with Garden type IV FNF undergoing hemiarthroplasty.

주관적 건강인식과 건강검진 결과의 비교분석을 통한 건강행위 연구 (A Study of Health Behavior through Comparative Analysis of Self-perceived Health Status and Health Examination Results)

  • 문상식;이시백
    • 보건교육건강증진학회지
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    • 제18권3호
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    • pp.11-36
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    • 2001
  • The purpose of this study is to analyze health behavior by comparing the difference between self-perceived health status and health examination results. The study subjects consist of 7,702 people aged over 20, surveyed by Health Interview survey, Health Examination survey, Dietary Life survey, Health Consciousness and Behavior survey. Data used in the study are drawn from raw data from a 1998 National Health and Nutrition survey. General characteristics variables are sex, age, education level, residential area, marital status, occupation, and living standard while dichotomous variables, ‘not healthy’ and ‘healthy’ are used to measure self-perceived health status. Variables for health examination results are high blood pressure, high cholesterol, diabetes, liver diseases, liver inflammation, kidney diseases, normal weight, regular diet, optimum sleeping time(7-8 hours), regular health examination and health behavior practice group. Major findings of the study are as follows: 1) Analysis of self-perceived health status and health behavior by disease: Variables significantly correlated with high self-perceived health status have strong associations with high health behavior practice, which supports the hypothesis that as one has high self-perceived health status, one is more likely to practice health promoting behavior. The results of analysis of health behavior differences by dividing subjects into two categories, ‘cases of illness’ and ‘cases of no illness’ indicate that drinking, sleeping time, health examination are significant variables (p〈0.001, 0.05) whereas smoking, weight control, regular exercise, regular diet are not significant. 2) Analysis of disparity patterns between self-perceived health status and health examination: The hypothesis that health behaviors would be different according to the disparity pattern between self-perceived health status and health examination is supported as a result of χ2 test. Among Type I : Self-perceived health status is high and actual health status is good (no disease) Type II: Self-perceived health status is high and actual health status is poor(have disease) Type III: Self-perceived health status is low and actual health status is good(no disease) Type IN: Self-perceived health status is low and actual health status is poor(have disease) Type I and Type IV show no disparity, Type I shows the highest health promoting behavior whereas Type IV shows the lowest health promoting behavior. Type II, and III, compared to Type I, practise lower health promoting behavior. Multi-logistics regression analysis was conducted to find out the degree of impact on health behavior. Independent variables are general characteristics, self-perceived health status and health examination result and presence of illness, while the dependent variable is health promoting behavior. The analysis of the impact of self-perceived health status on the health promoting behavior shows that smoking, drinking, weight control, regular exercise, health examination practice, and/or regular diet are significantly correlated to self-perceived health status. High self-perceived health status is inversely related to high health promoting behavior. This finding supports the hypothesis that the higher one perceives one's health, the more likely one is to practice health promoting behavior. On the contrary, the presence of illness has little impact on health promoting behavior. 3) Multiple logistics analysis on how disparity patterns between self-perceived health status and health examination affect health behavior: The results of multiple logistics analysis made on health behavior variables compared to the standard variable are as follows: When analyzed on the standard of Type I, smoking is a significant risk factor for the Type IV. In case of drinking, all the patterns show a high probability of relative risk ratio. With regard to weight control, it is a risk factor for Type II while all the patterns show high probability of not practising when analyzed on the standard of type IV. Type III and IV show high probability of not doing regular exercise while Type IV, shows a high probability of not taking appropriate sleeping time. When analyzed on the standard of type IV, all the patterns show a high probability of not taking health examinations. Type III and IV show a high probability of not having regular meals. As for overall health promoting behavior, Type III and IV show a high relative risk ratio. These two groups have low self-perceived health status. It implies that self-perceived health status has significant impact on health promoting behavior. This is also supported by the fact that Type I with high self-perceived health status and no illness shows a high practice rate of health promoting behavior. Types II and III the groups with high disparity between self-perceived health status and health examination results, show a low practice rate of health promoting behavior when compared to Type I. Type IV, that is the group with low self-perceived health status and actual illness, shows the lowest practice of health promoting behavior. It is highly probable that this type proves to be the poorest health group.

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