• Sijohaknonchong
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• v.26
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• pp.125-149
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• 2007

Until the late 19th century, $\ulcorner$Gagogwonryu(歌曲源流)$\lrcorner$ was a collection of songs which had powerful influence on Gagog tradition. However, its role on Gagog(歌曲) tradition since then is less well known. Generally, it is presumed that Gagog tradition might disappeared by giving way to modern song genre. So this article question that $\ulcorner$Gagogwonryu$\lrcorner$ became extinct rapidly between the late 19th century and early 20th century, and follow $\ulcorner$Gagogwonryu$\lrcorner$ tradition of early 20th century. Gagog instruction for beginner had a clue to answer this question. This instruction was written by Ha Son-il(河順一) who was a teacher and singer in a private music institute. named 'ChoyangGurakbu(調陽俱樂部). Accordingly, this article has processed two phases in order to find out this question. First of all, this article analyzed Gagog instruction that Ha soon-il edited. As a result, it found out that Gagog instruction included the whole $\ulcorner$Gagogwonryu$\lrcorner$'s contents in the 19th century and was transmitted actively until the early 20th century. Second, this article found out $\ulcorner$Gagogwonryu$\lrcorner$ tradition of the early 20th century by analyzing character of ChoyangGurakbu. And also this article discovered ChoyangGurakbu had been managed by an vigorous aid association. Gagog instruction for beginner written by Ha Son-il had spreaded from strength to strength in the early 20th century.

• Proceedings of the Korean Society of Marine Engineers Conference
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• 2011.06a
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• pp.263-263
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• 2011

• Transactions of the Korean Society for Noise and Vibration Engineering
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• v.21 no.5
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• pp.400-407
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• 2011

The suggested method of previous Son's study dichotomized subjective response data to modeling noise exposure-response. The method used maximum liklihood estimation instead of least square estimation and the noise exposure-response curve of the study was logistic regression analysis result. The method was originated to modeling community response rate such as %HA or %A. It can be useful when the subjective response was investigated based on predicted noise level. It is difficult to measure the single source emitting noise such as railway because various traffic noise sources combined in our life. The suggested method was adopted to model in this study and railway noise-exposure response curves were modeled because the noise level of this area was predicted data. The data of this study was used by previous Ko's paper but he dealt the area as combined noise area and divided the data by dominant noise source. But this study used all data of this area because the annoyance response to railway noise was higher than other noise according to the result of correlation analysis. The trend of the %HA and %A prediction model to train noise of this study is almost same as the model based on measured noise of previous Lim's study although the investigated areas and methods were different.

• Korean Journal of Acupuncture
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• v.39 no.2
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• pp.43-53
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• 2022

Objectives : Paeonia lactiflora Pallas (PLP) have been reported to have pharmacological effects such as anti-inflammatory and analgesic. However, it is not yet known whether PLP extract has anti-inflammatory effect on HaCaT cells, human keratinocyte. Methods : To confirm the anti-inflammatory effect of PLP on keratinocyte, TNF-𝛼/IFN-𝛾-stimulated HaCaT cells were used. HaCaT cells were pre-treated with PLP for 1h before stimulation with TNF-𝛼/IFN-𝛾. Then HaCaT cells were stimulated with TNF-𝛼/IFN-𝛾 for 24 h, the cells and media were harvested to measure the inflammatory cytokines levels. Granulocyte-macrophage colony stimulating factor (GM-CSF), monocyte chemoattractant protein-1 (MCP-1), interleukin 1 beta (IL-1𝛽), and TNF-𝛼 were analyzed by enzyme-linked immunosorbent assay (ELISA), and the mRNA expression of thymus and activation-regulated chemokines (TARC), IL-6, and IL-8 were measured by reverse transcription-polymerase chain reaction (RT-PCR). We also investigated the inhibitory mechanism of the mitogen-activated protein kinase (MAPKs) including ERK, JNK, and p38 and nuclear factor-kappaB (NF-𝜅B) by PLP using western blot. Results : PLP did not show cytotoxicity in HaCaT cells. In TNF-𝛼/IFN-𝛾-stimulated HaCaT cells, PLP significantly inhibited the expression of GM-CSF, MCP-1 IL-1𝛽, TNF-𝛼, TARC and IL-6. PLP inhibited the phosphorylation of ERK and translocation of NF-𝜅B into the nucleus. Conclusions : These results indicate that PLP could ameliorate the TNF-𝛼/IFN-𝛾-stimulated inflammatory response through inhibition of MAPK and NF-kB signal pathway. This suggests that PLP could be used beneficial agent to improve skin inflammation.

• Proceedings of the Korea Environmental Mutagen Society Conference
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• 2002.05a
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• pp.96-96
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• 2002

• Journal of Applied Biological Chemistry
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• v.59 no.3
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• pp.247-253
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• 2016

It confirmed the applicability as an anti-inflammatory material from Rubus occidentalis seed (RSE) extract. In HaCaT cells to evaluate the anti-inflammatory potential as a material RSE extract on the activity of the inflammatory factors caused by UVB and $IFN-{\gamma}/TNF-{\alpha}$. We measured the activity of ROS, interleukin-$1{\beta}$ ($IL-1{\beta}$), interleukin-6 (IL-6) and interleukin-8 (IL-8) by ROS-Glo $H_2O_2$ assay and ELISA kit. Our results showed that the RSE extracts inhibit the UVB and $IFN-{\gamma}/TNF-{\alpha}$-induced ROS activities and expression of $IL-1{\beta}$, IL-6 and IL-8 in a dose-dependent manner. Also it was found that inflammatory mediators of the expression of cyclooxygenase-2 (COX-2) inhibition were also brought, the expression of which is increased $PGE_2$ by COX-2 also inhibited. Finally RSE extracts measure the seed expression of filaggrin in the skin barrier, the main factor of the extract could be confirmed to increase the expression of the filaggrin damaged as a result of this concentration-dependent manner. Through this, it was able to confirm that the efficacy RSE extract to protect the inflammation by restoring the damaged layers of the epidermis. Results from more than RSE extract was able to confirm that the extract that has anti-inflammatory effects by improving the inflammation being produced from UVB.

• Childhood Kidney Diseases
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• v.10 no.2
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• pp.249-256
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• 2006

Diarrhea-associated hemolytic uremic syndrome(D+ HUS) is induced by enterohemorrhagic Escherichia coli(EHEC) and is characterized by the triad of microangiopathic hemolytic anemia, thrombocytopenia, and acute renal failure. The disease is usually transmitted by meat and water contaminated by excreta of domestic animals. We report a son and his mother with diarrhea-associated hemolytic uremic syndrome that spread within the family.

• Journal of Environmental Science International
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• v.15 no.1
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• pp.1-7
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• 2006

The purpose of this study is to illustrate the characteristics of soil organic matter (SOM) and partition coefficient $(K_{DOC})$. Humic substances (HS) from eight soils of varying properties were extracted by two different methods. The dissolved organic carbon (DOC) concentration was stabilized in 22hrs. The ratio of UV absorbance at 465nm and 665nm (E4/E6 ratio) for HS were similar pattern for 8 soils. The extraction with increasing pH increased dissolution of SON. The ratio of organic carbon (OC) associated with HA and FA (the HA:FA ratio) was varied widely in accordance with the soils and was highly correlated to OC $content(\%)$ of the soils. in modeling metal speciation in soils and soil solutions, assumptions that all DOC in soil solution is associated with FA and that HA:FA ratio in SOM is constant have been made. The results of this study indicate that the validity of these assumptions is questionable. By sequential pH extraction, the $K_{DOC}$ showed in a linear correlation with pH.

• Journal of the Korean Association of Oral and Maxillofacial Surgeons
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• v.30 no.3
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• pp.175-180
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• 2004

In this study, three treatment options to replace two posterior missing teeth were investigated using three dimensional finite element analysis: two wide(${\phi}5.0mm$) implants(the experimental model I), two standard(${\phi}3.75mm$) implants(the experimental model II), and three standard(${\phi}3.75mm$) implants(the experimental model III). Two kinds of load case were applied ; 1) perpendicular on occlusal surface(axial load), parallel on occlusal surface(lateral load). 2) perpendicular on occlusal surface(3mm lateral to central point). The results obtained from this study were as follows; value of Von-mises stress (equivalent stress) was smallest in the two wide implant among the three experimental models. It was reported that the diameter is the efficient factor than osseointegrated surface area.

• Journal of fish pathology
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• v.34 no.2
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• pp.243-248
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• 2021

Offshore wind power generation is an energy generation field that is rapidly developing owing to the increasing demand for clean energy. However, the physiological response of fish to the underwater noise generated during construction or operation of wind turbines is unclear. We confirmed the effects of sound pressures of 125, 135, 145, and 155 dB/µPa, including 140 dB/µPa (the standard sound pressure for noise damage recognition in South Korea), through serum analysis in rock bream (Oplegnathus fasciatus). High mortality induced by reduced immunity through artificial infection after stimulation was confirmed. These results suggest that rock bream is negatively affected by the noise generated during the construction of offshore wind power plants.