• Title/Summary/Keyword: General Science

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IL-35 Over-expression is Associated with Genesis of Gastric Cancer

  • Fan, Yong-Gang;Zhai, Jing-Ming;Wang, Wei;Feng, Bing;Yao, Guo-Liang;An, Yan-Hui;Zeng, Chao
    • Asian Pacific Journal of Cancer Prevention
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    • v.16 no.7
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    • pp.2845-2849
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    • 2015
  • Overexpression of interleukin (IL)-35 has been found in a variety of malignancies, but the expression status in gastric cancer has yet to be elucidated clearly. In the present study, positive expression of EBI3 and p35 was 63.3% and 70.0% of cases, respectively. EBI3 expression was strongly related with larger tumor size and invasion depth (P<0.05). Similarly, expression of p35 was also correlated with larger tumor size (P<0.05). These results indicate that IL-35 might be involved in growth of gastric cancer. Interestingly, EBI3 and p35 expressions were positive correlated with Ki-67 expression. Moreover, EBI3 immunoreactivity was associated with Bcl-2 staining. Our data suggest IL-35 is correlated with genesis of gastric cancer by regulating growth and apoptosis.

On Semi C-Reducibility of General (α, β) Finsler Metrics

  • Tiwari, Bankteshwar;Gangopadhyay, Ranadip;Prajapati, Ghanashyam Kr.
    • Kyungpook Mathematical Journal
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    • v.59 no.2
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    • pp.353-362
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    • 2019
  • In this paper, we study general (${\alpha}$, ${\beta}$) Finsler metrics and prove that every general (${\alpha}$, ${\beta}$)-metric is semi C-reducible but not C2-like. As a consequence of this result we prove that every general (${\alpha}$, ${\beta}$)-metric satisfying the Ricci flow equation is Einstein.

An Analysis of Pre-dental Hygiene Curriculum of Dental Hygiene Programs in USA and in Canada (미국과 캐나다의 전공전 치위생 교육과정 분석)

  • Cho, Young-Sik;Kim, Young-Jin;Ahn, Geum-sun
    • Journal of dental hygiene science
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    • v.6 no.1
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    • pp.41-45
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    • 2006
  • The objective of this research was to analyze and evaluate pre-dental hygiene curriculum of dental hygiene education program in USA and Canada. Sixty one programs were searched through their website. The curriculum include content in the four areas: general education, biomedical science, dental science, dental hygiene science. Pre-dental hygiene curriculum include content in general education and biomedical science. General education content include oral and written communications, psychology, and sociology. Biomedical science content include anatomy, physiology, chemisrty, biochemistry,immunology,general pathology, nutrition, and pharmacology. Pre-dental hygiene curriculum content provide the foundational knowledge and skill such as competencies to communicate effectively, to participate community health program, and to make decisions regarding dental hygiene service.

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Immature Oocyte-Specific Zap70 and Its Functional Analysis in Regulating Oocyte Maturation

  • Kim, Yun-Na;Kim, Eun-Ju;Kim, Eun-Young;Lee, Hyun-Seo;Kim, Kyeoung-Hwa;Lee, Kyung-Ah
    • Development and Reproduction
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    • v.13 no.3
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    • pp.145-153
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    • 2009
  • Previously, we obtained the list of genes differentially expressed between GV and MII oocytes. Out of the list, we focused on functional analysis of Zap70 in the present study, because it has been known to be expressed only in immune cells. This is the first report about the expression and its function of Zap70 in the oocytes. Synthetic 475 bp Zap70 dsRNA was microinjected into the GV oocytes, and the oocytes were cultured in vitro. In addition to maturation rates, meiotic spindle and chromosome rearrangements, and changes in expression levels of transcripts of three kinases, Erk1/2, JNK, and p38, were determined. Zap70 is highly expressed in immature GV oocytes, and gradually decreased as oocyte matured. When dsRNA of Zap70 was injected into the GV oocytes, Zap70 mRNA specifically and completely decreased by 2 hr and its protein expression also decreased significantly. Absence of Zap70 resulted in maturation inhibition at meiosis I (57%) with abnormalities in meiotic spindle formation and chromosome rearrangement. Concurrently, mRNA expression of Erk2, JNK, and p38, were affected by Zap70 RNAi. Therefore, we concluded that Zap70 is involved in MI-MII transition by affecting expression of MAP kinases.

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A Comparison of Self-Regulation and Sociality between Elementary Scientific Gifted Students and General Students (초등과학영재 학생과 일반학생의 자기조절능력과 사회성의 비교)

  • Lee, Yeo Jin;Choi, Sun Young
    • Journal of Korean Elementary Science Education
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    • v.35 no.4
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    • pp.406-415
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    • 2016
  • The purpose of this study was to compare self-regulation and sociality between elementary scientific gifted students and general students. The subjective students are composed of fifth and sixth grade elementary school students. A survey on self-regulation and sociality had been conducted to 106 general students, 38 gifted class students and 43 students in science educational institute for the gifted. The results of this study were as follows: First, the results of ANOVA test showed that the scientific gifted students were significantly better than general students on all subscales of self-regulation and sociality. Second, the results of correlation analysis indicated that self-regulation and sociality and their subscales were all highly positive relationship on students in science educational institute for the gifted, gifted class students and general students. Third, the results of multiple regression analysis showed that the motivational factor of self-regulation gave the greatest effect to the sociality of students in science educational institute for the gifted, whereas, the cognitive factor of self-regulation gave the greatest effect to the sociality of the general students and gifted class students.

A Comparative Analysis of GeneralMatch and DualGMatch in Time-Series Subsequence Matching (시계열 서브시퀀스 매칭에서 GeneralMatch와 DualGmatch의 비교 분석)

  • Lee, Sanghun;Moon, Yang-Sae
    • Proceedings of the Korea Information Processing Society Conference
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    • 2015.04a
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    • pp.751-754
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    • 2015
  • 최근 시계열 데이터베이스 기반의 다양한 응용 분야에서 서브시퀀스 매칭(subsequence matching)연구가 활발히 진행되고 있다. FRM과 DualMatch은 효과적인 서브시퀀스 매칭을 위해 처음 제안된 해결책이다. 이후 이들을 일반화한 GeneralMatch가 제안되었으며, 최근에는 GeneralMatch의 이원적 접근법인 DualGMatch가 제안되었다. 본 논문에서는 GeneralMatch와 DualGMath를 비교 분석 하고자 한다. 이를 위해, 먼저 윈도우 구성 관점에서 GeneralMatch와 DualGMatch를 평가한다. 다음으로, 두 해결책을 최대 윈도우 크기 효과와 인덱스 저장 효율 관점에서 이론적으로 비교 분석한다. 마지막으로, 실제 시계열 데이터를 활용하여 GeneralMatch와 DualGMatch의 인덱스 페이지 접근 횟수를 비교한다. 분석 결과, GeneralMatch가 윈도우 크기 효과와 인덱스 저장 효율 측면에서 DualGMatch보다 우수한 것으로 나타났다.

Comparison of Characteristics of Analogies on Saturated Solution Generated by Elementary School Teachers, General and Science-Gifted Students (포화 용액 개념에 대해 초등학교 교사와 일반 학생 및 과학영재 학생들이 만든 비유의 특성 비교)

  • Kang, Hun-Sik
    • Journal of Korean Elementary Science Education
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    • v.30 no.3
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    • pp.305-314
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    • 2011
  • In this study, the analogies on saturated solution generated by elementary school teachers were analyzed in their numbers, materials, and types aspects. The results were also compared with those of general and science-gifted elementary students. A test on the self-generating analogies on the target concept was administered to 111 elementary school teachers, 60 fifth graders at four science-gifted education institutes and 91 fifth graders at three elementary schools. The results revealed that the teachers made more analogies than the general and science-gifted students. In general, both the teachers and the students tended to make the analogies using the materials in family, riding, digestive, and school situations. However, there were a little difference between the teachers and the students in the cases of the analogies using other situations including body/physical activity. Similarly to the cases of the students, the teachers made more functional analogies than structural or structural/functional ones and did more concrete ones than abstract ones. However, they made more verbal, artificial, and enriched analogies than the students. They also made more highly systematic analogies than the general students, and did less ones than the science-gifted students. Educational implications of these findings are discussed.

Generalization of Window Construction for Subsequence Matching in Time-Series Databases (시계열 데이터베이스에서의 서브시퀀스 매칭을 위한 윈도우 구성의 일반화)

  • Moon, Yang-Sae;Han, Wook-Shin;Whang, Kyu-Young
    • Journal of KIISE:Databases
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    • v.28 no.3
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    • pp.357-372
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    • 2001
  • In this paper, we present the concept of generalization in constructing windows for subsequence matching and propose a new subsequence matching method. GeneralMatch, based on the generalization. The earlier work of Faloutsos et al.(FRM in short) causes a lot of false alarms due to lack of the point-filtering effect. DualMatch, which has been proposed by the authors, improves performance significantly over FRM by exploiting the point filtering effect, but it has the problem of having a smaller maximum window size (half that FRM) given the minimum query length. GeneralMatch, an improvement of DualMatch, offers advantages of both methods: it can use large windows like FRM and, at the same time, can exploit the point-filtering effect like DualMatch. GeneralMatch divides data sequences into J-sliding windows (generalized sliding windows) and the query sequence into J-disjoint windows (generalized disjoint windows). We formally prove that our GeneralMatch is correct, i.e., it incurs no false dismissal. We also prove that, given the minimum query length, there is a maximum bound of the window size to guarantee correctness of GeneralMatch. We then propose a method of determining the value of J that minimizes the number of page accesses, Experimental results for real stock data show that, for low selectivities ($10^{-6}~10^{-4}$), GeneralMatch improves performance by 114% over DualMatch and by 998% iver FRM on the average; for high selectivities ($10^{-6}~10^{-4}$), by 46% over DualMatch and by 65% over FRM on the average.

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Speculative Parallelism Characterization Profiling in General Purpose Computing Applications

  • Wang, Yaobin;An, Hong;Liu, Zhiqin;Li, Li;Yu, Liang;Zhen, Yilu
    • Journal of Computing Science and Engineering
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    • v.9 no.1
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    • pp.20-28
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    • 2015
  • General purpose computing applications have not yet been thoroughly explored in procedure level speculation, especially in the light-weighted profiling way. This paper proposes a light-weighted profiling mechanism to analyze speculative parallelism characterization in several classic general purpose computing applications from SPEC CPU2000 benchmark. By comparing the key performance factors in loop and procedure-level speculation, it includes new findings on the behaviors of loop and procedure-level parallelism under these applications. The experimental results are as follows. The best gzip application can only achieve a 2.4X speedup in loop level speculation, while the best mcf application can achieve almost 3.5X speedup in procedure level. It proves that our light-weighted profiling method is also effective. It is found that between the loop-level and procedure-level TLS, the latter is better on several cases, which is against the conventional perception. It is especially shown in the applications where their 'hot' procedure body is concluded as 'hot' loops.