• 제목/요약/키워드: G type

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알라닌 올리고머의 배좌구조에 관한 양자화학적 계산 (Quantum Chemical Calculations on the Conformational Structure of the Alanine Oligomer Model)

  • 심재호
    • 한국산학기술학회논문지
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    • 제16권2호
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    • pp.1563-1570
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    • 2015
  • 본 연구는 올리고펩티드의 연쇄성장 과정에서의 배좌의 변화를 조사하기 위하여 알라닌 올리고머 모델의 2량체 부터 5량체 까지 양자화학 계산(QCC)에 의한 구조최적화 계산을 하였다. 말단기의 영향을 확인하기 위하여 N말단 및 C말단이 공히 amide 구조를 갖는 "amide type" ($CH_3CONH-and-CONHCH_3$)과 N말단만이 methyl 구조를 갖는 "methyl type" ($CH_3NH-and-CONHCH_3$)의 2종류 모델을 준비하였다. 5량체 까지의 구조 최적화 계산 결과 3종류의 형태이성질체로 수렴이 되었다. 안정성이 높은 순서로 각각 ${\alpha}$ 나선형, PPII 유사형, ${\beta}$ 확장형으로 나타났으며, 사슬회전 방향이 서로 반대인 형태이성질체간의 에너지 값은 동일하게 나타났다 (5량체, "amide type" 좌 우회전형: ${\Delta}E=-1.05$, "methyl type" 좌 우회전형: ${\Delta}E=-1.62$). ${\alpha}$ 나선형의 모노머 단위당 에너지변화(${\Delta}E$)는 모노머의 증가와 함께 감소하였다.

$Guillain-barr{\acute{e}}$ 증후군(症候群)에 대한 동의학적(東醫學的) 고찰(考察) (병인병기(病因病機)와 변증시치(辨證施治)를 중심(中心)으로) (THE ORIENTAL MEDICINE STUDY ON G-B SYNDROME (Centering around the etiological factors pathological mechanism and dianosis and treatment))

  • 홍유성;황우준
    • 대한한의학회지
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    • 제16권1호통권29호
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    • pp.118-131
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    • 1995
  • According to the oriental medicine study on G.B.S, we obtained the result as follows : 1. G.B.S was inclined in flacid paralysis and pain and numbness(痺) in oriental medicine. 2. Etiology factors of G.B.S was classified exogenous and endogenous pathogenic factors. The formers was warmth and heat(濕熱), summer heat and dampness(暑濕), dampness and heat(濕熱), and cool and dampness(寒濕), the latter was the deficiency in both the spleen and the stomach(脾胃虛弱), deficiency of Yin(vital essence) in both the liver and kidney(肝腎陰虛) the factor of dampness and heat(濕熱) was most numerous. 3. Pathological mechanism of G.B.S was close connected with the five viscera - the spleen(脾), the stomach(胃), the liver(肝), the kidney(腎), the lung(肺) 4. Differentiation of Symptom-Complexes(辨症) in the G.B.S was consumption type of nutrient fluid due to heat symptom in the lung(肺熱傷津), fullness type of dampness and heat(濕熱侵淫), defiency type in both the spleen and the kidney(脾腎不足), deficiency type in both the spleen and the stomach(脾胃虛弱), deficiency type in the liver and the kidney(肝腎兩虛) 5. Acupuncture treatment for G.B.S was mainly Yangmoung channels of both the hand and the foot.(手足陽明經)

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A FIXED POINT THEOREM FOR NON-SELF G-CONTRACTIVE TYPE MAPPINGS IN CONE METRIC SPACE ENDOWED WITH A GRAPH

  • Sumitra, R.;Aruna, R.;Hemavathy, R.
    • Nonlinear Functional Analysis and Applications
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    • 제26권5호
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    • pp.1105-1114
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    • 2021
  • In this paper, we prove a fixed point theorem for G-contractive type non-self mapping in cone metric space endowed with a graph. Our result generalizes many results in the literature and provide a new pavement for solving nonlinear functional equations.

한약 처방 (복합체)의 Influenza Virus Type A에 대한 항바이러스 활성 효과 (Antiviral Activity of Korean Traditional Prescriptions against Influenza Virus Type A)

  • 정재득;고병섭;이형환;최환수;박갑주
    • 대한바이러스학회지
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    • 제26권2호
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    • pp.273-283
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    • 1996
  • In order to search for anti-influenza virus type A agents from Korean traditional prescriptions (herb complexes), we selected 63 traditional prescriptions, based on a review of the Korean traditional medicine books. Both methanol extracts and boiling-water extracts were tested, by means of the Haemagglutination Inhibition Test (HIT). Three of the 63 methanol extracts: CM-22, CM-26, CM-48 (see explanation of nomenclature below), showed efficacy against influenza virus type ACM-22 showed anti-influenza virus type A activity at the range of $313{\mu}g/ml$ to $9.75{\mu}g/ml$, CM-26 showed antiviral activity at the range of $156{\mu}l/ml$ to $4.87{\mu}g/ml$, CM-48 showed anti-influenza virus type A activity at the range of $625{\mu}g/ml$ to $19.5{\mu}g/ml$, respectively. Three of the water extracts: CW-14, CW-34, CW-61 were active. CW-14 showed anti-influenza virus type A activity at the range of l0mg/ml to $78{\mu}g/ml$, CW-34 showed antiviral activity at the range of 10mg/ml to $625{\mu}g/ml$ and CW-61 showed anti-influenza virus type A activity at the range of l0mg/ml to $313{\mu}g/ml$, respectively. In order to determine cytotoxicity of each extracts, chicken red blood cells were incubated with the various concentration of extracts of Korean traditional prescriptions. CW-14, CW-34 and CW-61 did not show cytotoxic effect against red blood cells whereas CM-22, CM-26 and CM-48 showed cytotoxic effect against red blood cells at the range of l0mg/ml to $625{\mu}g/ml$, 10mg/ml to $313{\mu}g/ml$ and 10mg/ml to $313{\mu}g/ml$, respectively. These results indicated that Korean traditional pres criptions may be inhibit either attachment of virus to cell surface receptor or penetration of the virus into cell during the initial stage of infection.

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FIXED POINT THEOREMS ON GENERALIZED CONVEX SPACES

  • Kim, Hoon-Joo
    • 대한수학회지
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    • 제35권2호
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    • pp.491-502
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    • 1998
  • We obtain new fixed point theorems on maps defined on "locally G-convex" subsets of a generalized convex spaces. Our first theorem is a Schauder-Tychonoff type generalization of the Brouwer fixed point theorem for a G-convex space, and the second main result is a fixed point theorem for the Kakutani maps. Our results extend many known generalizations of the Brouwer theorem, and are based on the Knaster-Kuratowski-Mazurkiewicz theorem. From these results, we deduce new results on collectively fixed points, intersection theorems for sets with convex sections and quasi-equilibrium theorems.

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GEOMETRY OF GENERALIZED BERGER-TYPE DEFORMED METRIC ON B-MANIFOLD

  • Abderrahim Zagane
    • 대한수학회논문집
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    • 제38권4호
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    • pp.1281-1298
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    • 2023
  • Let (M2m, 𝜑, g) be a B-manifold. In this paper, we introduce a new class of metric on (M2m, 𝜑, g), obtained by a non-conformal deformation of the metric g, called a generalized Berger-type deformed metric. First we investigate the Levi-Civita connection of this metric. Secondly we characterize the Riemannian curvature, the sectional curvature and the scalar curvature. Finally, we study the proper biharmonicity of the identity map and of a curve on M with respect to a generalized Berger-type deformed metric.

금강 하구 퇴적토의 이화학적 성질과 종속영양세균의 분포에 관하여 (Distribution of heterotrophic bacteria and physico-chemical characteristics of sediments in Kum river estuary)

  • 이건형;아영칠;홍순우
    • 미생물학회지
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    • 제24권3호
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    • pp.308-316
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    • 1986
  • Vertical distribution of heterotrophic bacteria and physico-chemical characteristics were measuted in Kum River estuarine sediments. And interrelationship between heterotrophic bacterka and environmental factors was also studied. The type of sediment of Site 1 was silty clay, and sand at Site 2. Annual pH ranges were between 7.1 and 7.7 in the clay type sediment (Site 1) and 6.9-7.2 in the sand type sediment (Site 2). It was shown that organic matter contents were higher in the clay type sediment than those of sand type sediment. Redox potential values of sediments were decreased rapidly with depth at Site 1, but those of Sete 2 showed vertical fluctuation. Nitrogens(ammonia+amino acid-N, nitrate-N, nitrite-N) and phosphate in the clay type sediment showed higher values than those of sand type sediment. Annual distribution of heterotrophic bacteria were ranged $6.71{\times}10^4$ cells/g dry wt. $-2.50{\times}10^6$ cells/g dry wt. In the clay type sediment and $2.67{\times}10^3$ cells/g dry wt. $-1.94{\times}10^6$ cells/g dry wt. in the sand type sediment. Distribution of proteolytic, lipolytic, and amylolytic bacteria were decreased with the depth and the highest density was found in April and the lowest in January. Bacterial populations in sediments were closely correlated with such environmental factors as pH, redox potential, moisture content, organic matter contents, and inorganic nutrients such as nitrite-N and phosphate-P.

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