• IMMUNE NETWORK
• /
• 제13권6호
• /
• pp.283-288
• /
• 2013

The pro-inflammatory cytokines tumor necrosis factor-${\alpha}$ (TNF${\alpha}$) and interleukin (IL)-$1{\beta}$ are crucial mediators involved in chronic inflammatory diseases. Inflammatory signal pathways regulate inflammatory cytokine expression-mediated by p38 mitogen activated protein kinase (p38MAPK). Therefore, considerable attention has been given to p38MAPK as a target molecule for the development of a novel anti-inflammatory therapeutics. BIRB 796, one of p38MAPK inhibitor, is a candidate of therapeutic drug for chronic inflammatory diseases. In this study, we investigated the effect of BIRB 796 on inflammatory cytokine productions by lipopolysaccharide (LPS) in different immune cell types. BIRB 796 reduced LPS-mediated IL-8 production in THP-1 cells but not in Raw 264.7 cells. Further analysis of signal molecules by western blot revealed that BIRB 796 sufficiently suppressed LPS-mediated phosphorylation of p38MAPK in both cell types whereas it failed to block inhibitor of kappa B (I-${\kappa}B$) degradation in Raw 264.7 cells. Taken together, these results suggest that the anti-inflammatory function of BIRB 796 depends on cell types.

• Journal of the Korean Institute of Telematics and Electronics T
• /
• 제35T권3호
• /
• pp.15-24
• /
• 1998

In this paper, we present new method of fractal image coding based on iterated function system(IFS) suggested by Barnsley. In previous Fractal coding using full searching algorithm, the quality of reconstructed image was better than other fractal coding method's, but it took a long time in that algorithm for searching domain blocks matched. And it is performed through linear affine transform, therefore it is difficult to approximate the complex range blocks. In this paper, using quadtree partitioning, complex blocks are divided into more smaller blocks, and simple blocks are merged to more larger blocks. So, we can got more precisely approximated range blocks and reduce the number of transformations. Hence, we have improved the compression ratio. In addition, we restrict the region of searching domains in order to reduce the searching time and coding time. Compared with full searching algorithm, we reduced coding time drastically, and quality of reconstructed image was better in terms subjective criteria. And compared with Monro's, our method is slower, but we could obtain a reconstructed image with better quality.

• Journal of the Institute of Electronics Engineers of Korea SC
• /
• 제37권3호
• /
• pp.55-62
• /
• 2000

This paper presents an analysis of the chaotic behavior in the discrete-time voltage mode chaotic generator fabricated using 0.8${\mu}{\textrm}{m}$ single poly CMOS technology. An approximated empirical equation is extracted from the measurement data of a nonlinear function block. Then the bifurcation diagram is simulated according to input variables and Lyapunov exponent λ which represent a dependence on an initial value is calculated. We show the interrelations among time waveforms, state transition, and power spectra for the state condition of chaotic circuit, such as equilibrium, periodic, and chaotic state. And results of experiments in the chaotic circuit with the $\pm$2.5V power supply and sampling clock frequency of 10KHz are shown and compared with the simulated results.

• Journal of the Institute of Electronics and Information Engineers
• /
• 제52권6호
• /
• pp.70-76
• /
• 2015

This paper introduces an FPGA self-test architecture reusing FPGA boundary scan chain as self-test circuits. An FPGA boundary scan cell is two or three times bigger than a normal boundary scan cell because it is used for configuring the function of input/output pins functions as well as testing and debugging. Accordingly, we analyze the architecture of an FPGA boundary scan cell in detail and design a set of built-in self-test (BIST) circuits in which FPGA boundary scan chain and a small amount of FPGA logic elements. By reusing FPGA boundary scan chain for self-test, we can reduce area overhead and perform a processor based on-board FPGA testing/monitoring. Experimental results show the area overhead comparison and simulation results.

• The Journal of the Korea institute of electronic communication sciences
• /
• 제12권2호
• /
• pp.345-352
• /
• 2017

In this paper, we design and implement an educational robot system that can use scratch education with the function of user demanding to perform robot education in actual school site in an embedded environment. It is developed to enable physical education for sensing information processing, software design and programming practice training that is the basis of robotic system. The development environment of the system is Arduino Uno based product using Atmega 328 core, debugging environment based on Arduino Sketch, firmware development language using C language, OS using Windows, Linux, Mac OS X. The system operation process receives the control command of the server using the Bluetooth communication, and drives various sensors of the educational robot. The curriculum includes Scratch program and Bluetooth communication, which enables real-time scratch training. It also provides smartphone apps and is designed to enable education like C and Python through expansion. Teachers at the school site used the developed products and presented performance processing results satisfying the missionary needs of the missionaries.

• Elastomers and Composites
• /
• 제34권2호
• /
• pp.113-120
• /
• 1999

Nobody doubts to say that one of the most important performance polymers is a conductive polymer. The manufacturing process of the commercial conductive polymers has been known by mixing with the conductive materials, but it doesn't noticeably appear of a conductive function. One of the reasons is the lack of comprehension In compounding a carbon black with polymer rosins. This paper involves the understanding of compounding technology of the conductive carbon black filled composite. Our experimental results indicate that the fibrous shaped carbon black was hard to process but appeared of a superior conductivity compared to a stick or a sphelulite shaped carbon black. Therefore, it was processed with a processing oil in compounding, which led to a better processability and a better conductivity. This study was accomplished that the solution process compared to the melting process.

• The Journal of The Korea Institute of Intelligent Transport Systems
• /
• 제16권6호
• /
• pp.195-207
• /
• 2017

Since the smart phone was first introduced, the amount of mobile traffic has increased explosively. The OTT service with personal broadcasting and TV contents and the number of users have been increased in wired network, and there are needs to expand the OTT service to mobile network. In the case of the OTT service in mobile network, the relative small and finite resource may cause the overload of the network due to the massive and high transfer rate. In this paper, we consider a future situation of the OTT user services in the cellular network and propose a novel D2D communication scheme for location-based OTT service, which can reduce and distribute the amount of video traffics. To effectively handle the traffic of OTT services, we propose D2DS and LCS functional blocks in EPC network, which can provide location-based service and D2D management. And, we suggest additional procedures for the location-based service of both content provider and contents receiver UEs with the operation of the proposed D2DS and LCS function block.

• Journal of the Institute of Electronics Engineers of Korea SP
• /
• 제42권6호
• /
• pp.63-72
• /
• 2005

In this paper, we propose the bit-rate control algorithm for the block based image compression like H.263, H.263+ or MPEG-4. The proposed algorithm is designed to identify the quantization parameter set through the Lagrangian optimization technique based on the well-known linear source model. We set the Lagrangian cost function with the rates and distortion calculated from the linear source model. We calculate the quantization parameter set using the Vitervi algorithm to solve the Lagrangian optimization problem considering the Dquant method of H.263 and MPEG-4. The proposed algorithm improves the video quality by up to 1.5 dB compared with the TMN8 scheme, and is more effective in the video sources with dynamic activities than the consistent quality approaches.

• Journal of the Institute of Electronics Engineers of Korea CI
• /
• 제37권5호
• /
• pp.45-53
• /
• 2000

This paper presents an analysis of the dynamical behavor in the chaotic neuron fabricated using 0.8${\mu}{\textrm}{m}$ single poly CMOS technology. An approximated empirical equation models for the sigmoid output function and chaos generative block of the chaotic neuron are extracted from the measurement data. Then the dynamical responses of the chaotic neuron such as biurcation diagram, frequency responses, Lyapunov exponent, and average firing rate are calculated with numerical analysis. In addition, we construct the chaotic neural networks which are composed of two chaotic neurons with four synapses and obtain bifurcation diagram according to synaptic weight variation. And results of experiments in the single chaotic neuron and chaotic neural networks by two neurons with the $\pm$2.5V power supply and sampling clock frequency of 10KHz are shown and compared with the simulated results.

• Bulletin of the Korean Chemical Society
• /
• 제34권2호
• /
• pp.447-452
• /
• 2013

In this study we report a new method for the synthesis of a silica monolithic column bed with bimodal pores (throughpores and mesopores). The template induced synthesis method was used to direct bimodal pores simultaneously instead of the usual post base-treating method. Block polymer Pluronic F127 was chosen as a dual-function template to form hierarchically porous silica monolith with both macropores and mesopores. This is a simplification of the method of monolithic column preparation. Poly(ethylene glycol) was used as a partial substitute for F127 can effectively prevent shrinkage during the monolith aging process without losing much surface area (944 $m^2/g$ to 807 $m^2/g$). More importantly, the resultant material showed a much narrower mesopore size (centered at 6 nm) distribution than that made using only F127 as the template reagent, which helps the mass transfer process. The solvent washing method was used to remove the remaining organic template, and it was proved to be effective enough. The new synthesis method makes the fabrication of the silica monolithic column (especially capillary column) much easier. All the structure parameters indicate that monolith PFA05 prepared by the above method is a good material for separation, with the merits of much higher surface area than usual commercial HPLC silica particles, suitable mesopore volume, narrow mesopore size distribution, low shrinkage and it is easily prepared.