• Bulletin of the Korean Chemical Society
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• 제33권7호
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• pp.2145-2148
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• 2012

A new thiourea based receptor (1) was synthesized and applied to fluoride ion recognition in acetonitrile solution. Receptor 1 displayed dual changes in absorption and fluorescence emission intensities selectively for fluoride ions. The interaction of 1 with fluoride undergoes a deprotonation process that is confirmed by $^1H$ NMR titration.

• 한국자기공명학회논문지
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• 제26권4호
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• pp.40-45
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• 2022

A small cage-like molecule (2) composed of three aminomethyl pyrroles and two hexa-substituted benzenes has been prepared by reduction of its iminopyrrole analogue (1) using NaBH₄. It was revealed by ¹H NMR spectroscopic analyses that cage molecule 2 strongly binds the fluoride anion in polar DMSO-d₆ relative to CDCl₃. Compared to that of compound 1, the lowered affinity of 2 for the fluoride anion is attributable to its increased electron density resulting from the production of thesecondary amine groups.

• 치위생과학회지
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• 제14권4호
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• pp.580-588
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• 2014

본 연구는 편의추출된 K대학교 학생들을 대상으로 치아우식예방 불화물에 관한 인식과 경험을 알아보고자 실시하였다. 2014년 5월 23일부터 6월 13일까지 대전지역 대학생들을 대상으로 총 450부의 설문지를 배부하여 444부가 회수되었고 응답이 불충분한 20부를 제외한 424부를 본 연구분석에 사용하였으며 치위생학과, 치위생학과를 제외한 보건계열, 비보건계열을 중심으로 비교분석하였다. 1. 치아우식예방을 위한 불소경험은 불소세치제 사용 치위생학과 68.9%, 보건계열 23.6%, 비보건계열 33.3%, 학교 불소용액양치사업 치위생학과 50.0%, 보건계열 46.3%, 비보건계열 44.1%. 시판 불소함유 구강세정제 사용 치위생학과 84.2%, 보건계열 72.4%, 비보건계열 62.2%, 전문가 불소도포 치위생학과 58.9%, 보건계열 30.9%, 비보건계열 30.6%, 수돗물불소농도조정사업 지역거주 치위생학과 13.7%, 보건계열 10.6%, 비보건계열 13.5%로 나타났다. 2. 비치위생학과 학생들은 불화물 사용의 목적 84.6%, 불소함유 구강세정제 63.2%, 불소함유 세치제 61.5%, 전문가 불소도포 56.4%, 수돗물불소농도조정사업 43.6% 순으로 인지하고 있었다. 3. 불화물에 대한 인식경로는 치위생학과 학생은 대학 강의가 가장 높았으나, 비치위생학과 학생은 인터넷과 방송, 보건교사 순이었고 대학강의에 관한 응답은 거의 없었으며 치과의료진에 의한 정보전달은 10%을 약간 상회하였다. 4. 불화물 이용 의향은 자녀를 위한 불소도포, 불소용액양치, 수돗물불소농도조정사업, 자신을 위한 불소도포 순으로 나타났으며, 불소이용시 필요정보는 불화물 부작용, 불화물이용 방법, 불화물이용 비용, 불화물 효과 순으로 나타났다. 5. 불화물을 경험한 군이 그렇지 않은 군에 비해서 불화물이용 의향이 높았으며, 공중구강보건사업보다는 개인이 선택하여 불화물을 경험한 군이 불화물이용에 더 긍정적이었다. 6. 불화물을 인지하는 군이 그렇지 않은 군에 비해서 불화물 이용의향이 높았으나, 불화불에 대한 부작용 인지여부는 이용의향에 영향을 끼치지 않았다. 따라서, 치아우식증 예방을 위한 불화물 인지와 경험은 불화물 이용에 영향을 미치므로 대중매체를 통한 교육 콘텐츠 개발 및 치과병의원을 통한 환자 개별 교육이 필요할 것으로 생각된다.

• Bulletin of the Korean Chemical Society
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• 제35권12호
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• pp.3437-3442
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• 2014

A well-known carbazole-based precursor (probe 1) was used for the detection of cysteine/homocysteine and fluoride. Probe 1 shows a "turn-on" response to cysteine/homocysteine and fluoride via enhancement in emission intensity at 442 nm and 462 nm respectively, in solutions and living cells. Furthermore, probe 1 behaves as a fluorescent molecular switch between cysteine/homocysteine and fluoride as the chemical inputs, which have been used for the development of a combinatorial logic circuit and a molecular keypad lock.

• Bulletin of the Korean Chemical Society
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• 제31권5호
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• pp.1204-1208
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• 2010

Anion recognition via hydrogen-bonding interactions could be monitored with changes in UV-vis absorption spectra and in some cases easily monitored with naked eye. Urea receptors 1 and 2 connected with both an azo group and a nitrophenyl group as a signaling group for color change proved to be an efficient naked eye receptor for the fluoride ion. The anion recognition phenomena of the receptors 1 and 2 via hydrogen-bonding interactions were investigated through UV-vis absorption and $^1H$ NMR spectra.

• 한국치위생학회지
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• 제6권2호
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• pp.165-174
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• 2006

In order to establish basic data before deciding on the ways to manage school dental hygiene project, this study polled 165 elementary school teachers. Collected data was used SPSS 12.0 statistics program and got the technical statistics and This research and analysis came to the following conclusion by using Fridmen rank test, Pearson's correlation. 1. To the question about how they acquire the knowledge of dental hygiene, 60.6 percent of elementary school teachers turned out to learn about it through mass media(TV, Internet, magazines). 2. Regarding the purpose to maintain dental hygiene, "the prevention of dental diseases" ranked highest, and next "the prevention of cavity" and "the cure of halitosis" appeared at the similar level, and "to become a good model of children" and "to serve the esthetic purpose" ranked lowest. 3. As to the ways to prevent cavity, regular visits to dental clinic and daily brushing turned out to be more effective preventation method. 4. As for the degree of recognition of fluoride, the correct answer about fluoride that is recovered slight caries is appeared 11.8%, that was lowest correct answer ratio.

• 대한소아치과학회지
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• 제28권1호
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• pp.159-165
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• 2001

치아우식의 예방을 목적으로 불소가 사용되어오고 있으며, 전문가 불소도포용으로 acidulated phosphate fluoride(APF) gel이 널리 사용되고 있다. 그러나 최근에는 fluoride varnish의 사용이 점차로 늘고 있으며, 이것은 유럽과 스칸디나비아에서 널리 사용되고 있다. 본 연구의 목적은 fluoride varnish와APF gel이 인공우식 병소에 미치는 영향을 비교연구하는 것이다. 소의 건전한 법랑질에 인공우식을 유발시킨 60개의 시편을 각 군당 20개씩, 세 군으로 나누었다. 1군은 대조군으로 어떠한 처치도 시행하지 않았다. 2군은 fluoride varnish를 도포후 1시간 후에 제거하였고, 3군은 APF gel을 도포후 1분 후에 제거하였다. 그리고 나서 생체외에서 매일 인공우식 용액에 3시간씩, 그리고 인공타액에 21시간씩 시편을 담그고 재광화/탈회 순환(remineralization/demineralization cycling)을 시행한 후 각각 5일 후와 15일 후에 미세경도를 측정하여 다음과 같은 결과를 얻었다. 1. 5일 후에 미세경도를 측정한 결과 2군과 3군은 1군에 비해 통계학적으로 유의성 있게 높았다(p<0.05). 그리고 15일 후에 측정한 결과도 2군과 3군이 1군에 비해 통계학적으로 유의성 있게 높았다(p<0.05). 2. 5일 후 2군과 3군의 미제경도를 비교시 각 군간 유의한 차이가 있었으며, 15일 후에도 각 군간 유의한 차이가 없었다. 3. 미세경도의 면화에 있어서 2군은 5일 후와 15일 후에 유의한 차이가 없었으며, 3군에서도 유의한 차이가 없었다. 그러나, 1군은 5일 후와 15일 후에 측정한 미세경도가 유의성 있게 감소하였다(p<0.05).

• Bulletin of the Korean Chemical Society
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• 제30권12호
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• pp.3031-3033
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• 2009

A new colorimetric anion sensor 1 has been synthesized based on both Fat brown RR dye and a nitrophenyl group. This new receptor 1 could recognize the presence of fluoride ion effectively and selectively by the change of color of solution. In addition, receptor 1 shows higher affinity for acetate, dihydrogenphosphate, and hydrogensulfate than the other anions such as chloride, bromide, iodide, perchlorate, and nitrate in acetonitrile.

• 한국치위생학회지
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• 제16권4호
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• pp.585-590
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• 2016

Objectives: The purpose of the study was to investigate oral health-related behaviors of some elementary school students by installation of toothbrushing facility. Methods: A self-reported questionnaire was completed, out by 377 elementary school students with toothbrushing facility, and by 260 elementary school students with no toothbrushing facility in M city from November to December, 2015. The data were analyzed by ${\chi}^2$-test, t-test and stepwise multiple regression analysis using SPSS 12.0 program. The questionnaire comprised toothbrushing practice(2 items), satisfaction of toothbrushing facility(1 item), oral health knowledge(4 items), fluoride recognition(1 item), and necessity of fluoride mouthrinse(1 item). Results: The level of oral health knowledge was high in toothbrushing facility school. But toothbrushing practice was higher in school of no toothbrushing facility(63.8%) than the school with toothbrushing facility(49.1%)(p<0.001). The number of brushing times a week was also higher in school of no toothbrushing facility(1.98 times) than the toothbrushing facility school(1.59 times)(p=0.011). The dominant reason for no brushing was not recognition(65.8%) in toothbrushing facility school, lack of places(61.3%) in non toothbrushing facility school. Conclusions: In order to improve the oral health in elementary school students, it is necessary to provide toothbrushing education and toothbrushing facility in elementary schools.

• Bulletin of the Korean Chemical Society
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• 제30권9호
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• pp.2101-2106
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• 2009

A series of facial amphiphiles 3,7-diaminocholestane were synthesized from 3,7-diketocholestane via 2 sequential reductive aminations and anion recognition was evaluated with acetate, chloride, bromide, fluoride and phosphate anions. The stereo-selective reductive amination protocol was utilized to synthesized facial amphiphiles afforded receptors in high yields. The molecular receptor 2 showed the highest binding constant with acetate in a 1:1 ratio.