• 대한한방부인과학회지
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• 제22권2호
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• pp.43-59
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• 2009

Purpose: This study was performed to determine the inhibitory effect of Persimmon Leaves extract (PL) on melanin synthesis in B16F10 melanoma cells B16F10. Methods: The inhibitory effects of PL on melanin synthesis were determined by in vitro assay. To elucidate inhibitory effects of PL on melanin synthesis, we determined the melanin release and melanin production in B16F10. And to investigate the action mechanism, we assessed the gene expression of tyrosinase, TRP-1, TRP-2, PKA, PKC${\beta}$, ERK-1, ERK-2, AKT-1, MITF in B16F10. Results: 1. PL inhibited melanin release, melanin production in B16F10. 2. PL inhibited tyrosinase activity in vitro and in B16F10. 3. PL suppressed the expression of tyrosinase, TRP-1, TRP-2 in B16F10. 4. PL suppressed the expression of PKA, PKC${\beta}$ in B16F10. 5. PL increased the expression of ERK-1, ERK-2, AKT-1 in B16F10. 6. PL suppressed the expression of MITF in B16F10. Conclusion: From these results, it may be concluded that PL is possesed of the antimelanogenetic effects.

• 한국가축번식학회지
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• 제12권2호
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• pp.77-83
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• 1988

This study was done with mouse embryo to assess effects of freezing media containing sucrose, freezing metods(1-F, 0.3$^{\circ}C$/min;2-F, 3-5$^{\circ}C$/min;3-F, 15$^{\circ}C$min;4-F, LN2 vapour) and cell freezers on the embryo survival determined using the FDA test. The results are summarized as follows. 1. The FDA score obtained with 1, 2, 3 and 4-F was 3.8, 3.6, 3.2 and 3.2, respectively. There was a significant difference(P<0.05) between 1-F, 3-F and 2-F, 4-F. 2. The score at the morular stage(3.8) higher(P<0.005) than the blastocyst stage of embryos(3.2). 3. No difference (P>0.05) was found between the score obtained with a automatic embryo freezer(4.0) and a liquid nitrogen container(3.7).

• Korean Journal of Mathematics
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• 제27권2호
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• pp.437-444
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• 2019

For c > -1, let ${\nu}_c$ denote a weighted radial measure on ${\mathbb{C}}$ normalized so that ${\nu}_c(D)=1$. For $c_1,c_2>-1$ and $f{\in}L^1(D^2,\;{\nu}_{c_1}{\times}{\nu}_{c_2})$, we define the weighted Berezin transform $B_{c_1,c_2}f$ on $D^2$ by $$(B_{c_1,c_2})f(z,w)={\displaystyle{\smashmargin2{\int\nolimits_D}{\int\nolimits_D}}}f({\varphi}_z(x),\;{\varphi}_w(y))\;d{\nu}_{c_1}(x)d{\upsilon}_{c_2}(y)$$. This paper is about the space $M^p_{c_1,c_2}$ of function $f{\in}L^p(D^2,\;{\nu}_{c_1}{\times}{\nu}_{c_2})$ ) satisfying $B_{c_1,c_2}f=f$ for $1{\leq}p<{\infty}$. We find the identity operator on $M^p_{c_1,c_2}$ by using invariant Laplacians and we characterize some special type of functions in $M^p_{c_1,c_2}$.

• 식물병연구
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• 제18권4호
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• pp.310-316
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• 2012

Gibberellea fujikuroi (Gf) 종복합체는 최소 15개의 종으로 구성되어 있으며, 대부분 식물에 병을 일으킬 뿐 아니라 푸모니신과 같은 곰팡이독소를 생성한다. 본 연구에서는 우리나라 벼와 옥수수로부터 분리한 Gf 종복합체 소속 야생형 균주의 푸모니신 생성능을 검정하였다. 이들 분석대상 균주는 모두 푸모니신 생합성에 필수적인 polyketide synthase 유전자 FUM1을 가지고 있는 것으로 확인되었다. 총 88주의 Gf 종복합체 소속 균주(55 F. fujikuroi, 10 F. verticillioides, 20 F. proliferatum, 2 F. subglutinans, 1 F. concentricum)와 Gf 종복합체의 근연종인 4주의 F. commune를 쌀 배지에 배양한 후 각 균주의 푸모니신 생성 농도를 HPLC 방법으로 측정하였다. 대부분의 F. verticillioides과 F. proliferatum 균주는 기주 식물에 관계없이 푸모니신 $B_1$($0.5-2,686.4{\mu}g/g$)과 $B_2$($0.7-1,497.6{\mu}g/g$)를 다양한 범위 내에서 생성하였다. 반면 모든 F. fujikuroi을 비롯한 다른 Fusarium spp.의 균주로부터는 푸모니신이 검출되지 않았거나 $10{\mu}g/g$ 이하 수준의 미량만 검출되었다. 흥미롭게도 F. proliferatum과 F. fujikuroi의 경우, 옥수수 유래 균주 집단에서 벼 유래 균주 집단에 비해 상대적으로 고농도 푸모니신 생성 균주의 비율이 높았다. 한편, FUM1 유전자를 함유하고 있는 F. commune의 푸모니신 생성능은 본 연구를 통해 처음 보고된다.

• Kyungpook Mathematical Journal
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• 제58권4호
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• pp.747-759
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• 2018

A graph G = (V (G), E(G) of order n = |V (G)| and size m = |E(G)| is said to be odd harmonious if there exists an injection $f:V(G){\rightarrow}\{0,\;1,\;2,\;{\ldots},\;2m-1\}$ such that the induced function $f^*:E(G){\rightarrow}\{1,\;3,\;5,\;{\ldots},\;2m-1\}$ defined by $f^*(uv)=f(u)+f(v)$ is bijection. While a bipartite graph G with partite sets A and B is said to be bigraceful if there exist a pair of injective functions $f_A:A{\rightarrow}\{0,\;1,\;{\ldots},\;m-1\}$ and $f_B:B{\rightarrow}\{0,\;1,\;{\ldots},\;m-1\}$ such that the induced labeling on the edges $f_{E(G)}:E(G){\rightarrow}\{0,\;1,\;{\ldots},\;m-1\}$ defined by $f_{E(G)}(uv)=f_A(u)-f_B(v)$ (with respect to the ordered partition (A, B)), is also injective. In this paper we prove that odd harmonious graphs and bigraceful graphs are equivalent. We also prove that the number of distinct odd harmonious labeled graphs on m edges is m! and the number of distinct strongly odd harmonious labeled graphs on m edges is [m/2]![m/2]!. We prove that the Cartesian product of strongly odd harmonious trees is strongly odd harmonious. We find some new disconnected odd harmonious graphs.

• 대한수학회보
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• 제33권4호
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• pp.531-536
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• 1996

Let $F$ denote $R$ or $C$. Put $A = SL(2, F)$. Define $P(F^2)$ to be the set of all 1-dimensional subspaces of $F^2$. Then the natural action of A on $F^2$ induces an action on $P(F^2)$.

• Asian-Australasian Journal of Animal Sciences
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• 제23권8호
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• pp.1034-1042
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• 2010

This study aimed to determine the optimum dietary crude protein level in a typical diet for fattening pigs fed ad libitum under normal climate conditions in Central Vietnam. One hundred and ninety two gilts of Mong Cai local breed (MC), $F_1$ Large White${\times}$Mong Cai and $F_2$ crossbreds of (Landrace${\times}$Mong Cai)${\times}$Large White were used. At the start of the experiment, Mong Cai pigs weighed 12 kg at 11 weeks of age, $F_1$ pigs 12.1 kg at 8 weeks of age and $F_2$ pigs 12.2 kg at 8 weeks of age. Four diets differing in crude protein (CP) content (10.1, 13.1, 16.1 and 18.9% in DM) were formulated from rice bran, corn meal, cassava meal and fish meal. Calculated digestible energy content of the diets ranged from 13.5 to 13.8 MJ per kg DM. Pigs were housed individually in pens of $2.5\;m^2$ each and had ad libitum access to feed in a trough as well as water in bowls. The final weights after a growing period of 150 days were 66, 86 and 96 kg for MC, $F_1$ and $F_2$, respectively. Feed intake of MC pigs was highest at 13.1% CP while $F_1$ and $F_2$ had the highest feed intake at 16.1% CP. The results showed that for MC the maximum gain was obtained at levels between 13 to 16% CP. For the $F_1$ the maximum gain was at dietary protein levels of 16-17%. For $F_2$ the max gain was obtained at CP levels of 16 to 18%. Feed conversion was highest in MC pigs (~4.0) followed by $F_1$ (~3.3) and $F_2$ (~3.1), and within genotypes was lowest at the optimum CP level (p<0.05). Back fat thickness in MC (33.1 mm), $F_1$ (23.0 mm) and $F_2$ (20.5 mm) pigs was different and within genotypes was the lowest at intermediate CP levels. In conclusion, increasing the dietary crude protein contents in practical diets for pigs in Vietnam can increase production on small holder farms. Optimal performance for MC, $F_1$ and $F_2$ pigs is achieved at different dietary crude protein contents.

• 음성과학
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• 제1권
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• pp.201-211
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• 1997

Acoustically a naturally-spoken vowel is composed of five formants. However, the acoustic quality of a vowel is known to be mostly determined by $F_1\;and\;F_2$. The main purpose of this study was to examine how synthesized vowels with $F_1\;and\;F_2$ are perceived by Korean native speakers. In addion, we are interested in finding whether the synthesized vowels are perceived differently by standard Korean speakers and Kyungnam regional dialect speakers. In the experiment 9 Seoul standard Korean speakers and 9 Kyungnam dialect speakers heard 536 vowels synthesized in vowel space with $F_1\;by\;F_2$ and categorized them into one of 10 Korean vowels. The resultant vowel map showed that each Korean vowel occupies an unique area in the two-dimensional vowel space of $F_1\;by\;F_2$, and confirmed that $F_1\;and\;F_2$ play important roles in the perception of vowels. The results also showed that the Seoul speakers and the Kyungnam speakers perceive the synthesized vowels differently. For example, /e/ versus /$\varepsilon$/ contrast, /y/, and /$\phi$/ are perceived differently by the Seoul speakers, whereas they were perceptually confused by the Kyungnam speakers. These results might be due to the different vowel systems of the standard Korean and the Kyungnam regional dialect. While the latter uses a six-vowel system which has no /e/ vs /$/ contrast, /v/ vs /i/ contrast, /y/, and /$\phi$/, the former recognizes these as different vowels. This result suggests that the vowel system of differing dialect restricts the perception of the Korean vowels. Unexpectedly /i/ does not occupy any area in the vowel apace. This result suggests that /i/ cannot be synthesized without $F_3$.

• Korean Journal of Mathematics
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• 제31권2호
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• pp.229-242
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• 2023

In this paper, we investigate the [p, q] - φ order and [p, q] - φ type of f₁ + f₁, ${\frac{f_1}{f_2}}$ and f₁ f₁, where f₁ and f₁ are analytic or meromorphic functions with the same [p, q]-φ order and different [p, q]-φ type in the unit disc. Also, we study the [p, q]-φ order and [p, q]-φ type of different f and its derivative. At the end, we investigate the relationship between two different [p, q] - φ convergence exponents of f. We extend some earlier precedent well known results.

• 대한수학회지
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• 제32권4호
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• pp.689-695
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• 1995

Let G be a finite group with k distinct conjugacy classes $C_1, C_2, \cdots, C_k$ and F an algebraically closed field such that char$(F){\dag}\left$\mid$ G \right$\mid$$. We denoted by $Irr_F$(G) the set of all irreducible F-characters of G and $Cf_F$(G) the set of all class functions of G into F. Then $Cf_F$(G) is a commutative F-algebra with an F-basis $Irr_F(G) = {\chi_1, \chi_2, \cdots, \chi_k}$.