• Spatial Information Research
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• 제11권4호
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• pp.453-464
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• 2003

지식정보사회에 있어 국가의 경쟁력은 유용한 지식과 정보가 얼마나 효율적이고 효과적으로 유통될 수 있는가에 따라 결정된다. 이에 정부는 제2차 국가GIS구축 기본계획을 수립하고 '지리정보의 전 국민 인터넷 유통 및 활용'을 목표로 국가지리정보유통망을 구축하고 있다. 그러나 각 부처별로 생산 구축한 지리정보를 유통하고자 하는 노력들이 동시에 진행되고 있어 다양한 경로로 여러 유통망에 접근해야 하는 문제가 제기되었다. 그러나 모든 시스템의 특성 및 환경에 부합하는 일원화된 연계방안을 제시하는 것은 어려운 일이다. 따라서 본 연구에서는 국가지리정보유통망과의 연계를 위해 고려해야 하는 사항이 무엇인지 연계 요소를 도출하고, 각 연계 요소별로 유형화한 연계방안을 제시하여 국가지리정보유통망과의 연계에 필요한 기준을 마련하였다.

• Biomolecules & Therapeutics
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• 제22권5호
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• pp.467-473
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• 2014

The purpose of this study is to investigate the memory enhancing effect and underlying molecular mechanism of arabinoxylan (AX), a major component of dietary fiber in wheat against scopolamine (SCO)-induced amnesia in Sprague-Dawley (SD) rats. Diverse behavior tests including Y-maze, Morris water maze, and passive avoidance tests were performed to measure cognitive functions. SCO significantly decreased the spontaneous alterations in Y-maze test and step-through latency in passive avoidance test, whereas increased time spent to find the hidden platform in Morris water maze test compared with the sham control group. In contrast, oral administration of AX (25 mg/kg and 50 mg/kg) effectively reversed the SCO-induced cognitive impairments in SD rats. Furthermore, AX treatment up-regulated the expression of brain-derived neurotrophic factor (BDNF) in the cortex and hippocampus via promoting activation of cAMP response element binding protein (CREB). Therefore, our findings suggest that AX can improve SCO-induced learning and memory impairment possibly through activation of CREB and up-regulation of BDNF levels, thereby exhibiting a cognition-enhancing potential.

• 의료ㆍ복지 건축 : 한국의료복지건축학회 논문집
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• 제16권1호
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• pp.25-33
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• 2010

This study is to realize the importance of the therapeutic environment of nursing facilities for elderly people; to comparatively analyze the therapeutic environment elements of the facilities in Gwangju, Jeonnam area, Seoul, and Japan by classifying the therapeutic environment elements according to two aspects on the basis of preceding studies; and to find out the differences among the three regional groupsnaFirst, all therapeutic elements were put together on the basis of two preceding studies based on the two aspects. Second, an expert group was organized primarily with architects and care-givers to find out the therapeutic environment elements of nursing facilities for elderly people with dementia, and to draw up an evaluation standard. Third, the regional differences were analyzed, by comparing the distribution of therapeutic elements of the facilities in Gwangju-Jeonnam area, Seoul, and Japan, through the found therapeutic environment elements. Consequently, eighteen therapeutic environment elements were found out of total 32 elements, and the elements were classified into nine factors based on the meaning of each element. The therapeutic environment elements were showed highest in Japan, and lowest in Gwangju-Chonnam area according to the comparative case analysis based on the nine factors. Especially, there were great regional differences in terms of awareness, safety, orientation, privacy, and freedom of choice.

• Advances in concrete construction
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• 제9권5호
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• pp.459-467
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• 2020

Mechanical and thermal properties of composite sandwich wall panels are affected by changes in their external environment. Humidity and temperature changes induce stress on wall panels and their core connectors. Under the action of ambient temperature, temperature on the outer layer of the wall panel changes greatly, while that on the inner layer only changes slightly. As a result, stress concentration exists at the intersection of the connector and the wall blade. In this paper, temperature field and stress field distribution of UHPC-RW-RC (Ultra-High Performance Concrete - Rock Wool - Reinforced Concrete) wall panel under high temperature-sprinkling and heating-freezing conditions were investigated by using the general finite element software ABAQUS. Additionally, design of the connection between the wall panel and the main structure is proposed. Findings may serve as a scientific reference for design of high performance composite sandwich wall panels.

• 한국멀티미디어학회논문지
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• 제13권10호
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• pp.1506-1513
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• 2010

게임 소프트웨어는 재미의 요소를 기반으로 한 고부가가치 산업이다. 성공적인 게임 소프트웨어 개발을 위해서는 재미에 대한 체계적인 분류와 탐색방법이 필요하다. 그러나 아직까지 '재미'에 대한 각기 다른 관점과 정의로 인하여 게임에서의 '재미'는 게임 기획자의 '경험'에 의해 단정지어지고 있으며 개발계획에서 어떤 재미요소가 고려되어야 하는지에 대한 모호함을 지니고 있다. 본 연구에서는 체계적인 분류를 위해 기존 문헌에서 발췌한 50개의 재미요소를 통계적 기법으로 분류 및 체계화하여 9개의 그룹 34개의 재미요소로 구조화하였다 이를 로제카이와의 놀이론을 적용하여 누락된 영역을 탐색하고, 탐색된 영역의 새로운 재미요소를 관련 웹 사이트에서 추출하여 1개 그룹 4개의 재미요소를 탐색하였다.

• Korean Chemical Engineering Research
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• 제55권4호
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• pp.556-560
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• 2017

A hemoglobin/silver nanoparticle heterolayer was fabricated for bioelectronic device with electrochemical signal-enhancement effect. As a device element, a hemoglobin, the metalloprotein, contained the heme group that showed the redox property was introduced for charge storage element. For electron transfer facilitation, a silver nanoparticle was introduced for electrochemical signal facilitation, the hemoglobin was immobilized onto Au substrate using chemical linker 6-mercaptohexanoic acid (6-MHA). Then, the silver nanoparticle was immobilized onto fabricated hemoglobin/6-MHA heterolayers by layer-by-layer (LbL) method. The surface morphology and surface roughness of fabricated heterolayer were investigated by atomic force microscopy (AFM). The redox property of hemoglobin/silver nanoparticle heterolayer was investigated by a cyclic voltammetry (CV) experiment for obtaining an oxidation potential and reduction potential. Moreover, for the assessing charge storage function, a chronoamperometry (CA) experiment was conducted to hemoglobin/silver nanoparticle-modified heterolayer electrode using oxidation and reduction potentials, respectively. Based on the results, the fabricated hemoglobin/silver nanoparticle heterolayer showed that an increased charge storage effect compared to hemoglobin monolayer-modified electrode.

• Tribology and Lubricants
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• 제27권1호
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• pp.7-12
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• 2011

Interest in advanced machining process such as AJM(abrasive jet machining) and CMP(chemical-mechanical polishing) using micro/nano-sized abrasives has been on the increasing demand due to wide use of super alloys, composites, semiconductor and ceramics, which are difficult to or cannot be processed by traditional machining methods. In this paper, the effects of pressure, wafer moving velocity and fluid viscosity were investigated by 2-dimensional finite element analysis method considering slurry fluid flow. From the investigation, it could be found that the simulation results quite corresponded well to the Preston's equation that describes pressure/velocity dependency on material removal. The result also revealed that the stress and corresponding material removal induced by the collision of particle may decrease under relatively high wafer moving speed due to the slurry flow resistance. In addition, the increase in slurry fluid viscosity causes the reduction of material removal rate. It should be noted that the viscosity effect can vary with the shape of abrasive particle.

• 한국소음진동공학회:학술대회논문집
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• 한국소음진동공학회 2014년도 추계학술대회 논문집
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• pp.99-101
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• 2014

A Comprehensive Vibration Assessment Program (CVAP) for steam generator internals (SGI) of Advanced Power Reactor 1400 (APR1400) is being performed in accordance with the United States Nuclear Regulatory Commission (U.S. NRC) Regulatory Guide 1.20 (RG 1.20) revision 3. This paper studies the vibration characteristics of moisture separator assembly as part of the vibration and stress analysis program for APR1400 SGI CVAP. The natural frequencies, mode shapes, and structural behavior of moisture separator assembly were investigated through modal analysis using finite element method and experimental measurement. Since the moisture separator consists of several items with complicated shape, an idealized shell model was used in the finite element analysis. Group of local modes caused by moisture separators and significant modes of shroud and separator support plate were identified. The results of this paper are to be utilized in the structural response analysis of moisture separator assembly.

• 한국산업보건학회지
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• 제24권1호
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• pp.79-90
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• 2014

Objectives: The aim of this study was to suggest preliminary data for the establishment of communication methodology of asbestos risk, fit for the features of each audiences, by grasping the features of risk communication by each element for each group survey. Methods: For this study, a questionnaire survey has been conducted from May to August 2012 and responses of 617 people including 214 school asbestos managers, 95 asbestos business managers, and 308 general public have been analyzed. Results: The feature by element of risk communication shows that to give information through non-governmental organizations with reliability such as colleges, research institutes, asbestos-related associations, etc among the entire investigated groups, is most effective. Lastly, for stakeholders related to asbestos, the public feedback for governmental asbestos management policy shows that it was considered that there is lack of reality due to comprehension deficit for situation, lack of a system of asbestos general management in the country and lack of policy connectivity among the branches of the government, and between the central government and the local government. However, the general public selected lack of various information disclosure, education, publicity for asbestos and lack of communication with citizens as the biggest problems.

• Journal of Microbiology
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• 제39권4호
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• pp.314-320
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• 2001

Macrophages stimulated by lipopolysaccharide(LPS) from gram negative bacteria undergo activation of a group of immediate early genes including Rantes. The mouse Rantes gene promoter region contains an LPS rsponsive element(LPE) We detected 3 specific bands termed B1, B2 and 3 formed by the interaction of the LPE and proteins found in LPS-stimulated RAW 367.7 cells. An additional band B4 was determined to be an Ap-1 binding protein. The B1 band appears within 1 hour of LPS nuclear extracts from LPS-stimulation, and this protein kinase enhances B1 and formation. The B1 band can be converted to band B2/B3 by adding specific heparin column fraction purified Ser/Thr specific protein phosphatases PP-1 and PP-2A can stimulate the same conversion to about the same extent. Thus, the formation of the LRE sequence binding complex appears to be regulated by Ser/Thr protein kinase and one or more Ser/Thr specific phosphatases. At least four proteins are involved in the trgulation of the LRE-dependent Rants experssion: two binding factors that bind directly to the target sequences. and two factors that control their binding. The future purification and characterization of these binding pro-teins will reveal in detail the mechanism of Rantes gene activation after LPS stimulation.