• Spatial Information Research
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• v.11 no.4
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• pp.453-464
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• 2003

The Competitive power of the country in knowledge information can be determined that how efficiently useful knowledge and information can be circulated. Korean government established the second National GIS Master Plan, and constructed National Geographic Information Clearinghouse to the goal 'whole nation's internet circulation of the geographic information and practical use'. But every departments of government are trying to circulate their geographic information individually, And this case, consumer group should approach to several dissemination network in various routing line to get the geographic information. In fact, it is difficult to present the solution for uilified single dissemination network. It is difficult to present suitable linkage plan coinciding in special environment and characteristics of all systems. Consequently, in this study, we suggested linkage element that should consider far link with National Geographic Information Clearinghouse, and presented linkage plan by linkage target type.

• Biomolecules & Therapeutics
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• v.22 no.5
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• pp.467-473
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• 2014

The purpose of this study is to investigate the memory enhancing effect and underlying molecular mechanism of arabinoxylan (AX), a major component of dietary fiber in wheat against scopolamine (SCO)-induced amnesia in Sprague-Dawley (SD) rats. Diverse behavior tests including Y-maze, Morris water maze, and passive avoidance tests were performed to measure cognitive functions. SCO significantly decreased the spontaneous alterations in Y-maze test and step-through latency in passive avoidance test, whereas increased time spent to find the hidden platform in Morris water maze test compared with the sham control group. In contrast, oral administration of AX (25 mg/kg and 50 mg/kg) effectively reversed the SCO-induced cognitive impairments in SD rats. Furthermore, AX treatment up-regulated the expression of brain-derived neurotrophic factor (BDNF) in the cortex and hippocampus via promoting activation of cAMP response element binding protein (CREB). Therefore, our findings suggest that AX can improve SCO-induced learning and memory impairment possibly through activation of CREB and up-regulation of BDNF levels, thereby exhibiting a cognition-enhancing potential.

• Journal of The Korea Institute of Healthcare Architecture
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• v.16 no.1
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• pp.25-33
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• 2010

This study is to realize the importance of the therapeutic environment of nursing facilities for elderly people; to comparatively analyze the therapeutic environment elements of the facilities in Gwangju, Jeonnam area, Seoul, and Japan by classifying the therapeutic environment elements according to two aspects on the basis of preceding studies; and to find out the differences among the three regional groupsnaFirst, all therapeutic elements were put together on the basis of two preceding studies based on the two aspects. Second, an expert group was organized primarily with architects and care-givers to find out the therapeutic environment elements of nursing facilities for elderly people with dementia, and to draw up an evaluation standard. Third, the regional differences were analyzed, by comparing the distribution of therapeutic elements of the facilities in Gwangju-Jeonnam area, Seoul, and Japan, through the found therapeutic environment elements. Consequently, eighteen therapeutic environment elements were found out of total 32 elements, and the elements were classified into nine factors based on the meaning of each element. The therapeutic environment elements were showed highest in Japan, and lowest in Gwangju-Chonnam area according to the comparative case analysis based on the nine factors. Especially, there were great regional differences in terms of awareness, safety, orientation, privacy, and freedom of choice.

• Advances in concrete construction
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• v.9 no.5
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• pp.459-467
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• 2020

Mechanical and thermal properties of composite sandwich wall panels are affected by changes in their external environment. Humidity and temperature changes induce stress on wall panels and their core connectors. Under the action of ambient temperature, temperature on the outer layer of the wall panel changes greatly, while that on the inner layer only changes slightly. As a result, stress concentration exists at the intersection of the connector and the wall blade. In this paper, temperature field and stress field distribution of UHPC-RW-RC (Ultra-High Performance Concrete - Rock Wool - Reinforced Concrete) wall panel under high temperature-sprinkling and heating-freezing conditions were investigated by using the general finite element software ABAQUS. Additionally, design of the connection between the wall panel and the main structure is proposed. Findings may serve as a scientific reference for design of high performance composite sandwich wall panels.

• Journal of Korea Multimedia Society
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• v.13 no.10
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• pp.1506-1513
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• 2010

Game Software is the high-value industry that is based on fun elements. To develop Game Software successfully, the method for systematically classifying and searching about fun elements needs. However, fun elements of game are still made by game developers 'experience', and have ambiguities about what are considered at development phase because of difference between viewpoints and definitions about them. We structured 9 groups and 34 fun elements after that 50 fun elements elicited from existing literature are classifies and refines by statistical analysis. And we found a omitted area with the result that the classified elements are applied to Roger Callois's Theory. Finally, we elicited new elements of omitted areas from web site and searched 1 group and 4 fun elements.

• Korean Chemical Engineering Research
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• v.55 no.4
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• pp.556-560
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• 2017

A hemoglobin/silver nanoparticle heterolayer was fabricated for bioelectronic device with electrochemical signal-enhancement effect. As a device element, a hemoglobin, the metalloprotein, contained the heme group that showed the redox property was introduced for charge storage element. For electron transfer facilitation, a silver nanoparticle was introduced for electrochemical signal facilitation, the hemoglobin was immobilized onto Au substrate using chemical linker 6-mercaptohexanoic acid (6-MHA). Then, the silver nanoparticle was immobilized onto fabricated hemoglobin/6-MHA heterolayers by layer-by-layer (LbL) method. The surface morphology and surface roughness of fabricated heterolayer were investigated by atomic force microscopy (AFM). The redox property of hemoglobin/silver nanoparticle heterolayer was investigated by a cyclic voltammetry (CV) experiment for obtaining an oxidation potential and reduction potential. Moreover, for the assessing charge storage function, a chronoamperometry (CA) experiment was conducted to hemoglobin/silver nanoparticle-modified heterolayer electrode using oxidation and reduction potentials, respectively. Based on the results, the fabricated hemoglobin/silver nanoparticle heterolayer showed that an increased charge storage effect compared to hemoglobin monolayer-modified electrode.

• Tribology and Lubricants
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• v.27 no.1
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• pp.7-12
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• 2011

Interest in advanced machining process such as AJM(abrasive jet machining) and CMP(chemical-mechanical polishing) using micro/nano-sized abrasives has been on the increasing demand due to wide use of super alloys, composites, semiconductor and ceramics, which are difficult to or cannot be processed by traditional machining methods. In this paper, the effects of pressure, wafer moving velocity and fluid viscosity were investigated by 2-dimensional finite element analysis method considering slurry fluid flow. From the investigation, it could be found that the simulation results quite corresponded well to the Preston's equation that describes pressure/velocity dependency on material removal. The result also revealed that the stress and corresponding material removal induced by the collision of particle may decrease under relatively high wafer moving speed due to the slurry flow resistance. In addition, the increase in slurry fluid viscosity causes the reduction of material removal rate. It should be noted that the viscosity effect can vary with the shape of abrasive particle.

• Proceedings of the Korean Society for Noise and Vibration Engineering Conference
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• 2014.10a
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• pp.99-101
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• 2014

A Comprehensive Vibration Assessment Program (CVAP) for steam generator internals (SGI) of Advanced Power Reactor 1400 (APR1400) is being performed in accordance with the United States Nuclear Regulatory Commission (U.S. NRC) Regulatory Guide 1.20 (RG 1.20) revision 3. This paper studies the vibration characteristics of moisture separator assembly as part of the vibration and stress analysis program for APR1400 SGI CVAP. The natural frequencies, mode shapes, and structural behavior of moisture separator assembly were investigated through modal analysis using finite element method and experimental measurement. Since the moisture separator consists of several items with complicated shape, an idealized shell model was used in the finite element analysis. Group of local modes caused by moisture separators and significant modes of shroud and separator support plate were identified. The results of this paper are to be utilized in the structural response analysis of moisture separator assembly.

• Journal of Korean Society of Occupational and Environmental Hygiene
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• v.24 no.1
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• pp.79-90
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• 2014

Objectives: The aim of this study was to suggest preliminary data for the establishment of communication methodology of asbestos risk, fit for the features of each audiences, by grasping the features of risk communication by each element for each group survey. Methods: For this study, a questionnaire survey has been conducted from May to August 2012 and responses of 617 people including 214 school asbestos managers, 95 asbestos business managers, and 308 general public have been analyzed. Results: The feature by element of risk communication shows that to give information through non-governmental organizations with reliability such as colleges, research institutes, asbestos-related associations, etc among the entire investigated groups, is most effective. Lastly, for stakeholders related to asbestos, the public feedback for governmental asbestos management policy shows that it was considered that there is lack of reality due to comprehension deficit for situation, lack of a system of asbestos general management in the country and lack of policy connectivity among the branches of the government, and between the central government and the local government. However, the general public selected lack of various information disclosure, education, publicity for asbestos and lack of communication with citizens as the biggest problems.

• Journal of Microbiology
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• v.39 no.4
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• pp.314-320
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• 2001

Macrophages stimulated by lipopolysaccharide(LPS) from gram negative bacteria undergo activation of a group of immediate early genes including Rantes. The mouse Rantes gene promoter region contains an LPS rsponsive element(LPE) We detected 3 specific bands termed B1, B2 and 3 formed by the interaction of the LPE and proteins found in LPS-stimulated RAW 367.7 cells. An additional band B4 was determined to be an Ap-1 binding protein. The B1 band appears within 1 hour of LPS nuclear extracts from LPS-stimulation, and this protein kinase enhances B1 and formation. The B1 band can be converted to band B2/B3 by adding specific heparin column fraction purified Ser/Thr specific protein phosphatases PP-1 and PP-2A can stimulate the same conversion to about the same extent. Thus, the formation of the LRE sequence binding complex appears to be regulated by Ser/Thr protein kinase and one or more Ser/Thr specific phosphatases. At least four proteins are involved in the trgulation of the LRE-dependent Rants experssion: two binding factors that bind directly to the target sequences. and two factors that control their binding. The future purification and characterization of these binding pro-teins will reveal in detail the mechanism of Rantes gene activation after LPS stimulation.