• BMB Reports
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• v.50 no.5
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• pp.247-256
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• 2017

CRISPR/Cas9 is the latest tool introduced in the field of genome engineering and is so far the best genome-editing tool as compared to its precedents such as, meganucleases, zinc finger nucleases (ZFNs) and transcription activator-like effectors (TALENs). The simple design and assembly of the CRISPR/Cas9 system makes genome editing easy to perform as it uses small guide RNAs that correspond to their DNA targets for high efficiency editing. This has helped open the doors for multiplexible genome targeting in many species that were intractable using old genetic perturbation techniques. Currently, The CRISPR system is revolutionizing the way biological researches are conducted and paves a bright future not only in research but also in medicine and biotechnology. In this review, we evaluated the history, types and structure, the mechanism of action of CRISPR/Cas System. In particular, we focused on the application of this powerful tool in autophagy research.

• Journal of the Korean Society of Clothing and Textiles
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• v.45 no.3
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• pp.510-524
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• 2021

Selfie practices on social media can result in negative body image for men. The current study investigated the dual body image pathway model for the relationship between selfie practices on social media and body satisfaction, with internalization as a mediator. Structural equation modeling analyses supported our research model when studying 446 young Korean male Instagram users. The results indicated that selfie editing behavior, but not selfie browsing behavior, significantly predicted an increased internalization of a body ideal. The positive associations between internalization, muscularity dissatisfaction, and body fat dissatisfaction were confirmed. Additionally, the indirect effects of selfie editing behavior on muscularity and body fat dissatisfaction due to internalization were significant. The study confirmed the detrimental effects of selfie behavior on body satisfaction for male social media users. The results provided valuable information that selfie editing may be a risky behavior since it can result in developing muscularity and body fat dissatisfaction. Theoretical contributions and practical implications were discussed. Future research should address the age and cultural differences that may elucidate the impacts of selfie practices on men's body image concerns.

• Journal of Korea Multimedia Society
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• v.11 no.6
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• pp.746-754
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• 2008

A 3D stereoscopic image is generated by interdigitating every scene with video editing tools that are rendered by two cameras' views in 3D modeling tools, like Autodesk MAX(R) and Autodesk MAYA(R). However, the depth of object from a static scene and the continuous stereo effect in the view of transformation, are not represented in a natural method. This is because after choosing the settings of arbitrary angle of convergence and the distance between the modeling and those two cameras, the user needs to render the view from both cameras. So, the user needs a process of controlling the camera's interval and rendering repetitively, which takes too much time. Therefore, in this paper, we will propose the 3D stereoscopic image editing system for solving such problems as well as exposing the system's inherent limitations. We can generate the view of two cameras and can confirm the stereo effect in real-time on 3D modeling tools. Then, we can intuitively determine immersion of 3D stereoscopic image in real-time, by using the 3D stereoscopic image preview function.

• Journal of the Korea Institute of Information and Communication Engineering
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• v.8 no.8
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• pp.1661-1669
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• 2004

A rapid development of Internet is changing users' desire from existing static contents to dynamic and diverse ones. Thus the SVG provides more affluent and sophisticated graphic expressions than an existing method based on bitmap, it can faithfully display vector graphics without scarifying any functions or the problem of device compatibility. In addition, it allows indexing, searching, storing, and sharing by the description of the logical structure of graphics. Since there are, however, very few people who know the complex SVG syntax and make use it, an editing system, which enables users to utilize the SVG graphics easily, has been in need. Therefore, in this thesis, we do research on basic technology on the SVG, design and make an editing system for SVG documents. The system, therefore, provides uses with a user-friendly editing interface and enables them to write graphic objects easily, and generates complex SVG documents automatically.

• Journal of Plant Biotechnology
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• v.44 no.1
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• pp.89-96
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• 2017

The CRISPR/Cas9 is a core technology that can result in a paradigm for breeding new varieties. This study describes in detail the sgRNA design, vector construction, and the development of a transgenic plant and its molecular analysis, and demonstrates how gene editing technology through the CRISPR/Cas9 system can be applied easily and accurately. CRISPR/Cas9 facilitates targeted gene editing through RNA-guided DNA cleavage, followed by cellular DNA repair mechanisms that introduce sequence changes at the site of cleavage. It also allows the generation of heritable-targeted gene mutations and corrections. Here, we present detailed procedures involved in the CRISPR/Cas9 system to acquire faster, easier and more cost-efficient gene edited transgenic rice. The protocol described here establishes the strategies and steps for the selection of targets, design of sgRNA, vector construction, and analysis of the transgenic lines. The same principles can be used to customize the versatile CRISPR/Cas9 system, for application to other plant species.

• The Journal of the Acoustical Society of Korea
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• v.23 no.5
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• pp.390-399
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• 2004

In this paper, we design and implement a multiple-view VoiceXML editor to improve editing efficiency of the VoiceXML. The VoiceXML multiple-view Editor uses a MVC framework to support multiple views and paradigm. Our multiple-view editor consists of Model. View and Controller using MVC framework. A model, core data structure. is constructed of abstract syntax tree and abstract grammar. A view. user interface. is formalized in unparsing rules and unparser. A controller. to control model and view. is made of command interpreter and tree handler. The VoiceXML multiple-view editor overcomes a drawbacks of existing XML editors by showing document structure and context concurrently. as well as document flows. Our VoiceXML multiple-view editor. which MVC framework has been applied, provides various editing views concurrently to users. Thereby. it supports efficient and convenient editing environments for voice-web documents to users and it guarantees transparency of editors. as various views have a same consistent model.

• Asia-Pacific Journal of Business
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• v.11 no.4
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• pp.65-81
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• 2020

Purpose - This research aims to investigate how consumers' eco-friendly product choice ratio changes as the benefits of eco-friendly products are framed as (1) non-monetary benefits, (2) monetary gain integrated with the loss or (3) monetary gain segregated from the loss. Design/methodology/approach - A mixed-design, scenario-based choice experiment was conducted. A series of chi-square tests and residual analyses were conducted to analyze the data. Findings - When the monetary gain was larger or slightly smaller than the loss, the participants' eco-friendly product choice ratio was higher when the monetary gain was integrated with the loss than those in the other two conditions. When the monetary gain was significantly smaller than the loss, the participants' eco-friendly product choice ratio was lower when the monetary gain was integrated with the loss than those in the other conditions. The ratio did not differ between the latter two conditions. Research implications or Originality - This research shows that marketers should frame the benefits of eco-friendly products and their costs in different manners depending on the relative magnitudes of them. This research also complements the existing literature by comparing the effectiveness of non-monetary framing of eco-friendly product benefits with that of monetary framing following hedonic editing hypothesis.

• Journal of Korea Game Society
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• v.11 no.4
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• pp.15-26
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• 2011

Game level design is a collaborative work to create a virtual world for a computer game including maps, agents, monsters, objects, players and events based on predefined its game scenario. It is a promising collaborative design application. The game level design generally requires much time and cost, as the size of its target game space becomes huge. However, traditional game level design tools do not provide concurrency control mechanisms among multiple participating game designers. They do not provide consistency of undo and redo mechanisms for erroneous collaborative tasks during iterative modifications and updates of collaborative tasks among multiple designers. In this paper, we propose a concurrency control and a collaborative editing mechanism to enhance productivity of the collaborative game level design. The proposed system provides hierarchical structures of shared objects and a concurrency control mechanism for each object. The proposed system also provides a consistent undo and redo mechanism to enhance modifications and updates on intermediate results of the level design procedures.

• Journal of the Korean Institute of Telematics and Electronics B
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• v.33B no.3
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• pp.28-37
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• 1996

To reduce an authors burden in hypermedia system that allows non-sequential information the process of creating links must be easy. However, most of the conventional hypermedia systems possess two difficulties. First, the author must go through several troublesome process to create a single link. Secondly, it is not easy to create an anchor in text or other multimedia data. Therefore, in order to support effective construction of hypermedia system the editing environment must provide an easy method to create links. In this paper, to resolve the weaknesses of conventional hypermedia system as mentioned above, an editing tool is developed and implemented to easily create the links of multimedia data. There are three methods in creating links and a user can select a convenient method in given circumstances. And for teh efficient production of nodes composed of multimedia information, we provide an authoring environment to integrate and process those informations.

• Journal of Internet Computing and Services
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• v.6 no.2
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• pp.117-126
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• 2005

The current text based XML document systems are editing text and don't perform syntax check. As a result, the validity of an edited XML document can't be decided it is well-formed or valid until it is parsed. This paper describes a design and implementation of the syntax-directed editing system for XML documents. Because this is tree-based system, it is easy to extend XML document. And this system is designed to validate XML documents in real-time, It is expected that this paper contributes XML related application developments.