• Korean Journal of Child Education & Care
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• v.18 no.1
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• pp.125-146
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• 2018

The purpose of this study was to examine the state of parent education experienced by parents and the state of child education at home relation to infant/preschooler abuse prevention. The subjects in this study were 302 selected parents who resided in I city and whose children were in infancy or early childhood. A survey was conducted, and frequency analysis or chi-square test was carried out after their answer sheets were gathered. The findings of the study were as follows: As for the state of parent education, the parents who received education related to infant/ preschooler abuse prevention accounted for 12.6 percent, and the parents who were taught about all the four types of abuse outnumbered the others who weren't. The parents received that education at institutions for early childhood education by experts in child abuse and early childhood education, and they replied they were satisfied with that education. As for the state of child education, the parents who replied they provided abuse prevention education for their children at home accounted for 25.2 percent, and they answered they taught about physical abuse and how to cope with abuse. They responded they started to conduct this education in their homes when their children were in infancy, and they did it frequently in daily life mainly through conversations. They told it's difficult for them to offer this education at home due to a shortage of abuse-related materials. And whether they offered that education for their children or not at home was significantly different according to whether they received parent education or not. Given the findings of the study, the necessity of the development of manuals for abuse prevention education that can easily be used at home without any modifications was suggested, and education on neglect and the revitalization of publicity are required as well.

• Childhood Kidney Diseases
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• v.8 no.2
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• pp.256-261
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• 2004

We report a case of severe(gradeV) unilateral vesicoureteral reflux(VUR) without any renal damage in a 6-month-old boy through the early sil)ling screening test for VUR, whose old brother had reflux nephropathy. The early detection of VUR aroused us to take special precautions to prevent urinary tract infection in this patient. We believe that this approach was helpful to reduce the risk of renal damage in this patient and are reporting the case with a brief review of related literatures. It is our firm suggestion that screening for vesicoureteral reflux should be carried out in every child who has siblings with refluf nephrouathy.

• Clinical and Experimental Pediatrics
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• v.54 no.2
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• pp.55-63
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• 2011

Prader-Willi syndrome (PWS) is a complex multisystem genetic disorder that is caused by the lack of expression of paternally inherited imprinted genes on chromosome 15q11-q13. This syndrome has a characteristic phenotype including severe neonatal hypotonia, early-onset hyperphagia, development of morbid obesity, short stature, hypogonadism, learning disabilities, behavioral problems, and psychiatric problems. PWS is an example of a genetic condition caused by genomic imprinting. It can occur via 3 main mechanisms that lead to the absence of expression of paternally inherited genes in the 15q11.2-q13 region: paternal microdeletion, maternal uniparental disomy, and an imprinting defect. Over 99% of PWS cases can be diagnosed using DNA methylation analysis. Early diagnosis of PWS is important for effective long-term management. Growth hormone (GH) treatment improves the growth, physical phenotype, and body composition of patients with PWS. In recent years, GH treatment in infants has been shown to have beneficial effects on the growth and neurological development of patients diagnosed during infancy. There is a clear need for an integrated multidisciplinary approach to facilitate early diagnosis and optimize management to improve quality of life, prevent complications, and prolong life expectancy in patients with PWS.

• Journal of Genetic Medicine
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• v.19 no.1
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• pp.27-31
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• 2022

X-linked dominant hypophosphatemic rickets are the most common form of familial hypophosphatemic rickets resulting from hypophosphatemia caused by renal phosphate wasting, which in turn is a result of loss-of-function mutations in PHEX. Herein, we report a 39-year-old female with short stature and skeletal deformities and 12-month-old asymptomatic daughter. The female has a history of multiple surgical treatments because of lower limb deformities. Her biochemical findings revealed low serum phosphorus levels with elevated serum alkaline phosphatase activity and normal serum calcium levels, suggesting presence of hypophosphatemic rickets. To identify the molecular causes, we used a multigene testing panel and found a mutation, c.667dup (p.Asp223GlyfsTer15), in PHEX gene. To the best of our knowledge, this is a novel mutation. A heterozygous form of the same variant was detected in daughter, who showed no typical symptoms such as bow legs, frontal bossing, or waddling gate, but presented early signs of impaired mineralization in both X-ray and biochemical findings. The daughter was initiated onto early medical treatment with oral phosphate supplementation and an active vitamin D analog. Because the daughter was genetically diagnosed based on a family history before the onset of symptoms, appropriate medical management was possible from early infancy.

• The Journal of the Convergence on Culture Technology
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• v.6 no.1
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• pp.403-411
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• 2020

The purpose of this study is to explore the construct system and revision emphasis of curriculum for early childhood education and care in japan revised in 2017. First, the construct system of the revised early childcare curriculum and kindergarten curriculum of the three institutions in 2017 is different. However, it is more specific according to its characteristics, and the revision focus is given in the same direction. Second, The revised emphasis of the curriculum establish itself with three qualities and abilities that must be nurtured through infancy and clarifies ten childhood images. Also, Emphasis is placed on the establishment of curriculum and management to implement these. Expert review is needed to ensure that the content presented in childhood images is appropriate and does not emphasize the establishment of curriculum and management without ensuring teacher autonomy.

• Journal of Korea Game Society
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• v.11 no.4
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• pp.163-174
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• 2011

The purpose of this study was to apply a variety of criteria to analyzing mobile applications for early childhood education, which are now available in application market, and was also to explore how the developmental characteristics and multimedia content characteristics of early childhood could be applied to mobile applications for early childhood education. To meet these purposes, this study targeted total 61 applications for infancy education in terms of mobile applications loaded on online education categories such as iPhone App Store and Android Market. Based on analytic criteria on the foundation of content type by learning type, cognitive load theory and multimedia design principle, this study analyzed those applications for early childhood. As a result, it was found that there were needs to develop a little more various categories of applications, and there were also needs to develop such applications that they can make the best use of smart phone's performance, comply with multimedia design principles but avoid any imprudent use of multimedia.

• Clinical and Experimental Pediatrics
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• v.52 no.12
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• pp.1321-1326
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• 2009

Prevalence of obesity in Korean children and adolescents has dramatically increased since the last 10-20 years. It is important to initiate prevention efforts early in childhood because prevalence of obesity in adolescence is the strongest predictor of its prevalence in adulthood. Intrauterine life, infancy, and preschool years may comprise the critical periods that are essential for the long-term regulation of energy balance therefore, obesity-prevention strategies should be initiated in utero and continued throughout childhood and adolescence. Families with high-risk children should be provided early education about maintaining normal weight. Encouraging physical activity and, especially, avoiding inactivity, are key challenges in the prevention of future obesity. Schools should be primarily involved in educating parents to discourage their children from excessively watching TV or playing computer games and eating unhealthy snacks and food. The involvement of medical practitioners is also important, especially, in the case of obese parents, obesity prevention strategies should be promoted from the first visit of pregnant women to the physicians. Health professionals can also be involved in obesity prevention because they are ideally equipped to identify young children at risk of obesity. Community and nation-wide efforts to increase awareness and promote environments that encourage physical activity and healthy nutrition are required.

• Journal of Chest Surgery
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• v.48 no.5
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• pp.307-310
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• 2015

Background: To evaluate our experience of early surgical plication for diaphragmatic eventration (DE) in infancy and childhood. Methods: This study evaluated infants and children with symptomatic DE who underwent plication through an open transthoracic approach in our childhood development department between January 2005 and December 2012. Surgical plication was performed in several rows using polypropylene U-stitches with Teflon pledgets. Results: The study included 12 infants and children (7 boys and 5 girls) with symptomatic DE (9 congenital and 3 acquired). Reported symptoms included respiratory distress (91.7%), wheezing (75%), cough (66.7%), and recurrent pneumonia (50%). Preoperative mechanical ventilatory support was required in 41.7% of the patients. The mean length of hospital stay was $6.3{\pm}2.5days$. The mean follow-up period was $24.3{\pm}14.5months$. Preoperative symptoms were immediately relieved after surgery in 83.3% of patients and persisted in 16.7% of patients one year after surgery. All patients survived to the end of the two-year follow-up and none had recurrence of DE. Conclusion: Early diagnosis and surgical plication of the diaphragm for symptomatic congenital or acquired diaphragmatic eventration offers a good clinical outcome with no recurrence.

• Journal of the Korean Home Economics Association
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• v.18 no.1
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• pp.83-95
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• 1980

The purpose of this study is to investigate the reasons of Object Attachment Occurrence in infant and the meanings of it in his early development. For this purpose, the following hypotheses were supposed. 1. Infant's object Attachment will be a substitutional for mother attachment when he has opportunities to his mother during his first years. 2. Infant's Object Attachment will not impede the infant's normal development. In order to test this hypotheses 28 mothers whose infants show or have shown this phenomenon and 28 mothers whose infants show or have shown this phenomenon and 28 mothers whose infants do not show this one were interviewed about their child rearing practice and attitude. They were selected by the random sampling method from 310 household wives living at a delux Apt. in Seoul. The results obtained in this study are as follow ; 1. The less opportunities infant has for 1) his mother's breast feeding 2) having physical contact with his mother 3) spending time with his mother 4) receiving prompt response from his mother to his crying, the more he is apt to show this phenomenon. And infant whose first main attachment figure is not his mother also shows the same apt. 2. There was no difference between two groups in intelligence and personality. So it can be concluded that infant's Object Attachment is a substitutional phenomenon for mother attachment in the mother during his first years, and it does not impede infant's normal development.

• Clinical and Experimental Pediatrics
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• v.55 no.7
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• pp.224-231
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• 2012

Prader-Willi syndrome (PWS) is a complex multisystem genetic disorder characterized by hypothalamic-pituitary dysfunction. The main clinical features include neonatal hypotonia, distinctive facial features, overall developmental delay, and poor growth in infancy, followed by overeating with severe obesity, short stature, and hypogonadism later in development. This paper reviews recent updates regarding the genetic aspects of this disorder. Three mechanisms (paternal deletion, maternal disomy, and deficient imprinting) are recognized. Maternal disomy can arise because of 4 possible mechanisms: trisomy rescue (TR), gamete complementation (GC), monosomy rescue (MR), and postfertilization mitotic nondisjunction (Mit). Recently, TR/GC caused by nondisjunction at maternal meiosis 1 has been identified increasingly, as a result of advanced maternal childbearing age in Korea. We verified that the d3 allele increases the responsiveness of the growth hormone (GH) receptor to endogenous GH. This paper also provides an overview of endocrine dysfunctions in children with PWS, including GH deficiency, obesity, sexual development, hypothyroidism, and adrenal insufficiency, as well as the effects of GH treatment. GH treatment coupled with a strictly controlled diet during early childhood may help to reduce obesity, improve neurodevelopment, and increase muscle mass. A more active approach to correct these hormone deficiencies would benefit patients with PWS.