• Journal of Magnetics
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• v.18 no.2
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• pp.142-149
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• 2013

We aim to monitor vascularization of early bone perfusion following rabbit lumbar intertransverse bone graft fusion surgery using magnetic resonance imaging assessment. Correlation with graft survival status was evaluated by histological method. Experimental animals were randomly divided into three groups and the model was established by operating bilateral lumbar intertransverse bone graft with different types of bone graft substitute material. The lumbar intertransverse area of three groups of rabbits was scanned via MRI. In addition, histological examinations were performed at the $6^{th}$ week after surgery and the quantitative analysis of the osteogenesis in different grafted area was carried out by an image analysis system. The MRI technique can be used for early postoperative evaluation of vascularized bone graft perfusion after transplantation of different bone materials, whereas histological examination allows direct visualization of the osteogenesis process.

• The Journal of Korean Academic Society of Nursing Education
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• v.16 no.2
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• pp.312-320
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• 2010

Purpose: This study was done to compare the comprehension and knowledge about delirium in nurses working at long-term care hospitals (NLH) with nurses working at a general hospital (NGH). Method: The participants were 191 nurses from a general hospital and 7 long-term care hospitals in Chungnam. The tool for comprehension consisted of the needs and importance of delirium education and the confidence of management for early detection, caring and prevention of delirium. The tool for knowledge of delirium developed by the author consisted of causing factors, symptoms, caring and prevention of delirium. Result: The comprehension of need and importance of delirium education was higher than the confidence for delirium management in participants. NLH nurses had a higher level in comprehension of the need and importance of delirium education and a lower level in confidence of delirium management than NGH nurses. The mean for delirium knowledge was 75.32% for all participants. The knowledge of NLH nurses was significantly lower than those of NGH nurses. All nurses showed low scores in confidence and knowledge of delirium prevention. Conclusion: A systematic educational program for nurses to enhance the ability for assessment, early detection and prevention of delirium for institutionalized elderly patients needs to be developed.

• Journal of Sasang Constitutional Medicine
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• v.28 no.2
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• pp.184-192
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• 2016

Objectives The purpose of this case study is to report significant improvement of headache, constipation and a slight improvement of tremor after treatment with Hyeongbangjihwhang-tang in a Soyangin patient with Parkinson's disease.Methods This Soyangin patient is treated by Hyeongbangjihwhang-tang and acupuncture therapy. The progress was evaluated using the Unified Parkinson Disease Rating Scale before and after treatment. Secondary results assessments include Global Assessment Scale, change of patient's omniloquilism, Xerostomia and Cold hands & Feet Syndrome.Results and Conclusions The patient's symptoms of headache, constipation and tremor were improved after using Hyeongbangjihwhang-tang. and UDPRS score decreased in Part Ⅰ, Part Ⅱ, and Part Ⅲ. In conclusion, this study shows that Hyeongbangjihwhang-tang can be effective treatment for Soyangin patient with early-stage Parkinson''s disease. Overall, Sasang medicine can be a solution of the symptoms caused by Parkinson's disease. Through Sasang medicine we can contribute Parkinson's disease Patient's quality of life get better.

• Journal of Korean Society of Occupational and Environmental Hygiene
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• v.19 no.2
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• pp.156-169
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• 2009

In this study, the authors introduced DASH (Disabilities of the arm, shoulder, and hand), which had been developed for evaluating the functional impairment in the movement of upper extremities in regular daily activities, work ability and sports/performing arts ability. It is an ergonomic risk assessment tool used for industrial workers and also a disability measurement tool for upper extremity disorders arising from musculoskeletal disorders and symptom. This study intended to examine the applicability of DASH in occupational health field. Firstly, DASH development process and composition were reviewed through The DASH outcome measure user's manual and early articles. Secondly, reliability, validity, and responsiveness of the DASH in various languages at the application stage as well as its reliability and validity at the early stage of development were investigated. Thirdly, focusing on the application of DASH to clinical cases, workers with musculoskeletal symptoms, healthy workers, workers with other diseases, and general population were discussed besides workers with major musculoskeletal disorders. Lastly, DASH questionnaire was examined for its potential as a reference for assessing the functional impairment in the movement of upper extremities of workers with musculoskeletal symptoms in industrial workers in Korea.

• Journal of Genetic Medicine
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• v.15 no.2
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• pp.110-114
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• 2018

Ataxia-telangiectasia (AT; OMIM 208900) is a rare autosomal recessive inherited progressive neurodegenerative disorder, with onset in early childhood. AT is caused by homozygous or compound heterozygous mutations in ATM (OMIM 607585) on chromosome 11q22. The average prevalence of the disease is estimated at 1 of 100,000 children worldwide. The prevalence of AT in the Republic of Korea is suggested to be extremely low, with only a few cases genetically confirmed thus far. Herein, we report a 5-year-old Korean boy with clinical features such as progressive gait and truncal ataxia, both ankle spasticity, dysarthria, and mild intellectual disability. The patient was identified as a compound heterozygote with two novel genetic variants: a paternally derived c.5288_5289insGA p.(Tyr1763*) nonsense variant and a maternally derived c.8363A>C p.(His2788Pro) missense variant, as revealed by next-generation sequencing and confirmed by Sanger sequencing. Based on claims data from the Health Insurance Review and Assessment Service Republic of Korea, we calculated the prevalence of AT in the Republic of Korea to be about 0.9 per million individuals, which is similar to the worldwide average. Therefore, we suggest that multi-gene panel sequencing including ATM should be considered early diagnosis.

• Women's Health Nursing
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• v.27 no.1
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• pp.27-39
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• 2021

Purpose: This study aimed to review recent findings from birth cohort studies on maternal and child environmental health. Methods: Birth cohort studies regarding environmental health outcomes for mothers and their children were investigated through a systematic review. A literature search was conducted in PubMed, CINAHL, the Cochrane Library, Embase, and RISS to identify published studies using the keywords using a combination of the following keywords: maternal exposure, environmental exposure, health, cohort, and birth cohort. Articles were searched and a quality appraisal using the Newcastle-Ottawa Scale for cohort studies was done. Results: A review of the 14 selected studies revealed that prenatal and early life exposure to environmental pollutants had negative impacts on physical, cognitive, and behavioral development among mothers and children up to 12 years later. Environmental pollutants included endocrine disruptors, air pollution (e.g., particulate matter), and heavy metals. Conclusion: This systematic review demonstrated that exposure to environmental pollutants negatively influences maternal and children's environmental health outcomes from pregnancy to the early years of life. Therefore, maternal health care professionals should take steps to reduce mothers' and children's exposure to environmental pollutants.

• Journal of Chest Surgery
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• v.55 no.4
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• pp.325-331
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• 2022

Postoperative critical care management for lung transplant recipients in the intensive care unit (ICU) has expanded in recent years due to its complexity and impact on clinical outcomes. The practical aspects of post-transplant critical care management, especially regarding ventilation and hemodynamic management during the early postoperative period in the ICU, are discussed in this brief review. Monitoring in the ICU provides information on the patient's clinical status, diagnostic assessment of complications, and future management plans since lung transplantation involves unique pathophysiological conditions and risk factors for complications. After lung transplantation, the grafts should be appropriately ventilated with lung protective strategies to prevent ventilator-induced lung injury, as well as to promote graft function and maintain adequate gas exchange. Hypotension and varying degrees of pulmonary edema are common in the immediate postoperative lung transplantation setting. Ventricular dysfunction in lung transplant recipients should also be considered. Therefore, adequate volume and hemodynamic management with vasoactive agents based on their physiological effects and patient response are critical in the early postoperative lung transplantation period. Integrated management provided by a professional multidisciplinary team is essential for the critical care management of lung transplant recipients in the ICU.

• Journal of Gastric Cancer
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• v.22 no.4
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• pp.306-318
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• 2022

Gastric cancer (GC) is associated with high morbidity and mortality rates. Thus, early diagnosis is important to improve disease prognosis. Endoscopic assessment represents the most reliable imaging method for GC diagnosis; however, it is semi-invasive and costly and heavily depends on the skills of the endoscopist, which limit its clinical applicability. Therefore, the search for new sensitive biomarkers for the early detection of GC using noninvasive sampling collection methods has attracted much attention among scientists. Urine is considered an ideal biofluid, as it is readily accessible, less complex, and relatively stable than plasma and serum. Over the years, substantial progress has been made in screening for potential urinary biomarkers for GC. This review explores the possible applications and limitations of urinary biomarkers in GC detection and diagnosis.

• Proceedings of the Korea Water Resources Association Conference
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• 2023.05a
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• pp.95-95
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• 2023

Common hydrological problems of developing countries include poor data management, insufficient measuring devices and ungauged watersheds, leading to small or unreliable data availability. This has greatly affected the adoption of artificial intelligence techniques for flood risk mitigation and damage control in several developing countries. While climate datasets have recorded resounding applications, but they exhibit more uncertainties than ground-based measurements. To encourage AI adoption in developing countries with small ground-based dataset, we propose data augmentation for regression tasks and compare performance evaluation of different AI models with and without data augmentation. More focus is placed on simple models that offer lesser computational cost and higher accuracy than deeper models that train longer and consume computer resources, which may be insufficient in developing countries. To implement this approach, we modelled and predicted streamflow data of the Asa River Watershed located in Ilorin, Kwara State Nigeria. Results revealed that adequate hyperparameter tuning and proper model selection improve streamflow prediction on small water dataset. This approach can be implemented in data-scarce regions to ensure timely flood intervention and early warning systems are adopted in developing countries.

• International Journal of Computer Science & Network Security
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• v.23 no.5
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• pp.53-64
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• 2023

Early detection of endometrial carcinoma in uterus is essential for effective treatment. Endometrial carcinoma is the worst kind of endometrium cancer among the others since it is considerably more likely to affect the additional parts of the body if not detected and treated early. Non-invasive medical computer vision, also known as medical image processing, is becoming increasingly essential in the clinical diagnosis of various diseases. Such techniques provide a tool for automatic image processing, allowing for an accurate and timely assessment of the lesion. One of the most difficult aspects of developing an effective automatic categorization system is the absence of huge datasets. Using image processing and deep learning, this article presented an artificial endometrium cancer diagnosis system. The processes in this study include gathering a dermoscopy images from the database, preprocessing, segmentation using hybrid Fuzzy C-Means (FCM) and optimizing the weights using the Whale Optimization Algorithm (WOA). The characteristics of the damaged endometrium cells are retrieved using the feature extraction approach after the Magnetic Resonance pictures have been segmented. The collected characteristics are classified using a deep learning-based methodology called Long Short-Term Memory (LSTM) and Bi-directional LSTM classifiers. After using the publicly accessible data set, suggested classifiers obtain an accuracy of 97% and segmentation accuracy of 93%.