• Title/Summary/Keyword: E4

Search Result 31,822, Processing Time 0.049 seconds

Design and implementation of e-mail extraction engine for mobile with image conversion facilities. (이미지 변환 엔진을 탑재한 모바일용 전자우편 추출 엔진의 설계 및 구현)

  • 정영지
    • Journal of the Korea Institute of Information and Communication Engineering
    • /
    • v.7 no.4
    • /
    • pp.638-645
    • /
    • 2003
  • In existing internet, e-mail protocols including POP3 and IMAP4, provide e-mail services fir exchanging messages with texts, hypertext and images as well. For the e-mail services in wireless mobile network, mobile e-mail service providers have to install a mobile exclusive e-mail server or have to convert e-mail to mobile exclusive e-mail with wireless application format in case of POP3 protocol. In the e-mail service of IMAP4 case known as web-mail, it is difficult to view e-mail directly from server without IMAP4 mobile client because e-mail is stored in mail server side with remote file server. In either case, it also has the problems of viewing the e-mail of hypertext and image information at mobile. This paper provides e-mail extraction engine with image and hypertext conversion facilities that can be applied in wireless mobile internet and it is optimized in mobile communication environments such as a small display, small size of memory with web-mail protocol based on IMAP4 as well as POP3 mail protocol.

Variability in the Viral Protein Linked to the Genome of Turnip Mosaic Virus Influences Interactions with eIF(iso)4Es in Brassica rapa

  • Li, Guoliang;Zhang, Shifan;Li, Fei;Zhang, Hui;Zhang, Shujiang;Zhao, Jianjun;Sun, Rifei
    • The Plant Pathology Journal
    • /
    • v.37 no.1
    • /
    • pp.47-56
    • /
    • 2021
  • Plants protect against viruses through passive and active resistance mechanisms, and in most cases characterized thus far, natural recessive resistance to potyviruses has been mapped to mutations in the eukaryotic initiation factor eIF4E or eIF(iso)4E genes. Five eIF4E copies and three eIF(iso)4E copies were detected in Brassica rapa. The eIF4E and eIF(iso)4E genes could interact with turnip mosaic virus (TuMV) viral protein linked to the genome (VPg) to initiate virus translation. From the yeast two-hybrid system (Y2H) and bimolecular fluorescence complementation (BiFC) assays, the TuMV-CHN2/CHN3 VPgs could not interact with BraA.eIF4E.a/c or BraA.eIF(iso)4E.c, but they could interact with BraA.eIF(iso)4E.a in B. rapa. Further analysis indicated that the amino acid substitution L186F (nt T556C) in TuMV-UK1 VPg was important for the interaction networks between the TuMV VPg and eIF(iso)4E proteins. An interaction model of the BraA. eIF(iso)4E protein with TuMV VPg was constructed to infer the effect of the significant amino acids on the interaction of TuMV VPgs-eIF(iso)4Es, particularly whether the L186F in TuMV-UK1 VPg could change the structure of the TuMV-UK1 VPg protein, which may terminate the interaction of the BraA.eIF(iso)4E and TuMV VPg protein. This study provides new insights into the interactions between plant viruses and translation initiation factors to reveal the working of key amino acids.

Increased Frequency of Apolipoprotein E4 Genotype in Childhood Minimal Change Nephrotic Syndrome (MCNS) (소아 미세변화 신증후군 환자에서 Apolipoprotein E4 유전자형에 관한 연구)

  • Kim Sung-Do;Bae Young-Min;Cho Byoung-Soo;Cho Yoe-Won;Kim Il-Soo
    • Childhood Kidney Diseases
    • /
    • v.5 no.2
    • /
    • pp.87-99
    • /
    • 2001
  • Purpose: We studied to find out apo-E genotype polymorphism in minimal change nephrotic syndrome(MCNS) and IgA nephropathy(IgAN) and to determine the relationship between apo-E genotype and clinical course of MCNS. Materials and Method: 43 MCNS patients and 15 IgAN patients were examined for apo-E polymorphism. 50 healthy blood donors were examined for apo-E genotype as control. Genomic DNA was prepared front peripheral blood leukocytes according to standard procedures. Results: As compared with control group, e4 allele frequency was significantly increased in MCNS (p<0.01). However, in IgAN e2 allele frequency, however, was 2.6 times higher than normal control (P<0.01). The frequency of e4 allele of frequent relapser group was 4.6 times higher than normal control and was 2 times higher than infrequent relapser group. Conclusion: We think that apo-E typing might be one of the parameters, which should be considered to predict the course of MCNS in children. MCNS with risky HLA profile and E4/4 genotype could indicate the need for a longer steroid administration. And apo-E genotype needs to be considered for the evaluation of therapeutic responses to other drugs. (J, Korean Soc Pediatr Nephrol 2001 ; 5 : 87-99)

  • PDF

The Study of Synergy between the BchE-k Variant and the ApoE Gene in the Alzheimer Dementia of the Korean Population

  • Shin, Eun-Sim;Yoon, Song-Ro;Choi, Soo-Kyung;Kim, Soo-Young
    • Journal of Genetic Medicine
    • /
    • v.3 no.1
    • /
    • pp.29-32
    • /
    • 1999
  • The Apolipoprotein E type 4 allele (ApoE ${\varepsilon}4$) is genetically associated with the common late onset familial and sporadic forms of Alzheimer's disease. The BchE-k variant, which is the common variant of the BchE gene, has been reported to show allelic association with AD in subjects who are also carriers of the ${\varepsilon}4$ allele of the ApoE, especially in subjects over the age of 75. This study was performed to evaluate the distribution of the ApoE and the BchE genotypes in the healthy and AD groups and to evaluate the synergy between the BchE-k variant and the ApoE ${\varepsilon}4$ in AD. The ApoE and the BchE genotypes were determined in DNA samples from 610 healthy people and 60 LOAD patients by using ARMS by standard agarose gel electrophoresis. The effect of the ApoE ${\varepsilon}4$ was closely related to AD(p<0.05). A comparison between the AD patients and the healthy individuals, both with the ${\varepsilon}4$ allele, indicated an interaction between the BchE-k and the ApoE ${\varepsilon}4$(p<0.05). The association of the BchE-k with AD was limited to carriers of the ApoE ${\varepsilon}4$ allele, among whom the presence of the BchE-k gave an odds ratio of AD 3.48 (95% C.I. 1.3-9.2). Therefore, these results suggested that further evidence of an association between the ApoE ${\varepsilon}4$ and LOAD, and the BchE-k acts in synergy with the ApoE ${\varepsilon}4$ as a susceptibility gene for AD.

  • PDF

Synthesis of New 2,4-Disubstituted Thiazoles and 2-(Allylidenehydrazono)-thiazolo[5,4-b]quinoxaline Derivatives (새로운 2,4-이치환된 티아졸들과 2-(Allylidenehydrazono)-thiazolo[5,4-b]quinoxaline 유도체들의 합성)

  • Kim, Jong-Geun;Bae, Sun Kun
    • Applied Chemistry for Engineering
    • /
    • v.20 no.2
    • /
    • pp.134-139
    • /
    • 2009
  • A series of allylidenethiosemicarbazone compounds (2a~2e) were obtained in 45~85% by condensing (E)-3-(aryl)acrylaldehyde (1a~1e) with thiosemicarbazide. Theses compounds on treatment of 2,4'-dibromoacetophenone and 2,3-dichloroquinoxaline yielded 2,4-disubstituted thiazoles (3a~3e) and 2-[(E)-3-(aryl)allylidenehydrazono]thiazolo[5,4-b]quinoxaline (4a~4e) in good yield respectively. The structures of all the newly synthesized compounds were identified by IR and $^1H-NMR$ spectral data.

Design and implementation of e-mail extraction engine for mobile with image conversion facilities. (이미지 변환 엔진을 탑재한 모바일용 전자우편 추출 엔진의 설계 및 구현)

  • 윤호범;김명삼
    • Proceedings of the Korea Multimedia Society Conference
    • /
    • 2003.05b
    • /
    • pp.628-634
    • /
    • 2003
  • In existing internet, e-mail protocols including POP3 and IMAP4, provide e-mail services for exchanging messages with texts, hypertext and images as well. For the e-mail services in wireless mobile network, mobile e-mail service Providers have to install a mobile exclusive e-mail server or have to convert e-mail to mobile exclusive e-mail with wireless application format in case of POP3 protocol. In the e-mail service of IMAP4 case known as web-mail, It is difficult to view e-mail directly from server without IMAP4 mobile client because e-mail is stored in mail server side with remote file server. In either case, it also has the problems of viewing the e-mail of hypertext and image information at mobile, This Paper Provides e-mail extraction engine with image and hypertext conversion facilities that can be applied in wireless mobile internet and it is optimized In mobile communication environments such as a small display, small size of memory with web-mail protocol based on IMAP4 as well as POP3 mail protocol.

  • PDF

GORENSTEIN SEQUENCES OF HIGH SOCLE DEGREES

  • Park, Jung Pil;Shin, Yong-Su
    • Journal of the Korean Mathematical Society
    • /
    • v.59 no.1
    • /
    • pp.71-85
    • /
    • 2022
  • In [4], the authors showed that if an h-vector (h0, h1, …, he) with h1 = 4e - 4 and hi ≤ h1 is a Gorenstein sequence, then h1 = hi for every 1 ≤ i ≤ e - 1 and e ≥ 6. In this paper, we show that if an h-vector (h0, h1, …, he) with h1 = 4e - 4, h2 = 4e - 3, and hi ≤ h2 is a Gorenstein sequence, then h2 = hi for every 2 ≤ i ≤ e - 2 and e ≥ 7. We also propose an open question that if an h-vector (h0, h1, …, he) with h1 = 4e - 4, 4e - 3 < h2 ≤ (h1)(1)|+1+1, and h2 ≤ hi is a Gorenstein sequence, then h2 = hi for every 2 ≤ i ≤ e - 2 and e ≥ 6.

Development of 4E&E Learning Cycle Model using Learning Motivation for School Science (과학 교과에서 학습 동기 전략을 활용한 4E&E 순환학습모형의 개발)

  • Ha, Tae-Kyoung;Shim, Kew-Cheol;Kim, Hyun-Sup;Park, Young-Chul
    • Journal of The Korean Association For Science Education
    • /
    • v.28 no.6
    • /
    • pp.527-545
    • /
    • 2008
  • This paper suggested a 4E&E Learning Cycle Model using learning motivation for students in science education. The model has been developed on the basis of motivational and instructional design. The 4E&E Learning Cycle Model has four phases such as engage, explore, explain and expand, and two subsidiary phases such as evaluate, and feedback provided with at each phase. The model has gone a process of instruction with learning effects evaluation and providing feedback in science classroom, which facilitate to increase the effectiveness of learning activities. Especially, the 4E&E Learning Cycle Model using motivational learning strategies makes the learners be attractive to and immersed in instruction. This model has potentials in educating students in science education.

Effects of Dietary Polyunsaturated Fatty Acids and Vitamin E Supplementation on Vitamin E Levels of Serum, Liver and Brain in Chicks at Different Ages (과량의 비타민 E 첨가 및 다불포화지방 식이가 Age가 다른 Chick의 혈청과 조직 비타민 E 농도에 미치는 영향)

  • 정은정
    • Journal of Nutrition and Health
    • /
    • v.22 no.3
    • /
    • pp.209-217
    • /
    • 1989
  • The present study examined the effects of dietary PUFA and vitamin E supplementation(2,000 I.U./Kg diet) on vitamin E levels of serum, liver and brain in chicks aged one week (younger chick) and four weeks(older chick). 1) Younger chicks showed more sensitive response to vitamin E supplementation in the diet than older chicks in their serum levels, but not in liver levels. 2) Chicks fed excess vitamin E showed significantly higher levels of vitamin E in both serum and liver than unsupplemented groups. 3) PUFA diet lowered serum and liver vitamin E levels especially for vitamin E supplemented groups except for older chick liver at 3 weeks of the experimental period. 4) Vitamin E levels of brain were relatively lower than those of serum and liver and showed little change according either to the dietary PUFA or to vitamin E supplementation.

  • PDF

Syntheses and Biological Activities of Potential Antifungal Allylamine Compounds (항진균 알릴아민 화합물의 합성과 활성평가)

  • Chung Byung-Ho;Cheon Seung-Hoon;Chung Soon-Young
    • YAKHAK HOEJI
    • /
    • v.49 no.4
    • /
    • pp.299-305
    • /
    • 2005
  • Structure-activity relationship studies of allylamine type of antimycotics were carried out to evaluate the effect of naphthyl and methyl portion of naftifine. Compounds with 3,4-difluorophenyl (2a-5a), 4-hydroxyphenyl (2b-5b), 3-nitro­phenyl (2c-5c), 4-chlorobenzothiazoly (2d-5d) and 5-methylfurfural (2e-5e) instead of naphthyl group, and with hydrogen (3a-3e), methyl (4a-4e) and ethyl (5a-5e) in the place of methyl in naftifine were synthesized and tested for their in vitro anti-fungal activities against five different fungi. Fourteen compounds (3a, 4a, 5a, 3b, 4b, 5b, 3c, 4c, 5c, 3d, 4d, 3e, 4e and 5e) showed significant anti-fungal activities against T. mentagrophytes. (E)-N-(3-Phenyl-2-propenyl)-3,4-difluoro-ben­zenemethaneamine(3a), (E)_N_(3_phenyl_2_propenyl)_4_hydroxy_benzenemethaneamine(3b) and (E)-N-ethyl-N-(3-phenyl­2-propenyl)-3-nitro-benzenemethaneamine (5c) displayed moderate anti-fungal activities against all five different fungi.