• Wind and Structures
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• 제9권2호
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• pp.159-178
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• 2006

For the slender and flexible cable supported bridges, identification of all the flutter derivatives for the vertical, lateral and torsional motions is essential for its stability investigation. In all, eighteen flutter derivatives may have to be considered, the identification of which using a three degree-of-freedom elastic suspension system has been a challenging task. In this paper, a system identification technique, known as covariance-driven stochastic subspace identification (COV-SSI) technique, has been utilized to extract the flutter derivatives for a typical bridge deck. This method identifies the stochastic state-space model from the covariances of the output-only (stochastic) data. All the eighteen flutter derivatives have been simultaneously extracted from the output response data obtained from wind tunnel test on a 3-DOF elastically suspended bridge deck section-model. Simplicity in model suspension and measurements of only output responses are additional motivating factors for adopting COV-SSI technique. The identified discrete values of flutter derivatives have been approximated by rational functions.

• 한국전산유체공학회:학술대회논문집
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• 한국전산유체공학회 2010년 춘계학술대회논문집
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• pp.242-246
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• 2010

To determine the trajectories and the impact of rain drops on the facade of a tall building, a particle tracking method is employed form steady state simulation of turbulent flow around the building. The simulation is performed for the upper part of the building comprising a detailed louver system. Rain is trapped at relative high rates on the roof and the penthouse, with Local Intensity Factors (LIF's) of the order of 1. The upper parapets and upper floors get a fair amount of wetting with LIF's of the order of 0.6. The wetting decreases downwards reaching values of 0.2 to 0.25 at the level of the louver system.

• Journal of the Korean Society for Industrial and Applied Mathematics
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• 제15권2호
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• pp.97-122
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• 2011

Fluid dynamics driven by pumping without valves (valveless pumping) shows interesting physics. Especially, the driving function to generate valveless pump mechanism is one of important factors. We consider a closed system of valveless pump which consists of flexible tube part and stiffer part. Fluid and structure (elastic tube) interaction motions are generated by the periodic compress-and-release actions on an asymmetric location of the elastic loop of tubing. In this work, we demonstrate how important the driving forcing function affects a net flow in the valveless circulatory system and investigate which parameter set of the system gives a more efficient net flow around the loop.

• 한국정밀공학회지
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• 제32권1호
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• pp.17-24
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• 2015

Smart factory requires 4 Zero factors including Zero Waiting-time, Zero Inventory, Zero Defect, Zero Down-time) that needs IT convergence for production resources of 4M1E(Man, Machine, Material, Method, Energy) in real time and event processing in all type of manufacturing enterprises. This paper will be explaining about core emerging production IT convergence technologies including cyber device security, 4M1E integration, real time event driven architecture, common platform of manufacturing standard applications, smart factory to-be model for small and medium manufacturing enterprises.

• 산업경영시스템학회지
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• 제30권3호
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• pp.71-81
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• 2007

Government-driven informatization support projects for small and medium companies turn into collaborative information technology alliances between mother companies and their suppliers. These collaboration efforts are driven by a mother company that can influence and support its suppliers. A mother company establishes a proprietary evaluation system for suppliers' informatization level and enforces the suppliers to use their ERP (Enterprise Resource Planning) systems above a certain level. This paper presents a Samsung Electronics case to find determinant factors for ERP system usage level. This case study aims at providing long-term strategies for the collaboration project and helping the suppliers effectively pursue their informatization projects. Furthermore, the case study will reveal issues and tasks for the mother companies to accomplish sustainable success for their suppliers' informatization.

• Journal of Advanced Marine Engineering and Technology
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• 제32권4호
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• pp.611-617
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• 2008

In ubiquitous environments, the content adaptable services can be dynamically provided to adapt the frequent changes of contexts. These services have common things that the kinds of context factors are limited to ubiquitous environment, though the contexts are flexible. To reuse service architecture can be reasonable for effective adaptable service. In this paper, we design a software architecture with product line techniques for content adaptable applications in ubiquitous environment. Description of product line is to define variation points and their variants, to find out the dependencies between them and to keep the model based architecture, their alternatives.

• 기술혁신학회지
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• 제7권2호
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• pp.373-395
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• 2004

In year 2003, the Daedeok Science Town(DST) has celebrated its 30 years of anniversary and achievement in science and technology development. However, there is a criticism that DST has not played its expected role in Korea's National Innovation System. Recognizing this criticism, the development of DST was evaluated in the perspective of innovation cluster. The research shows that DST has been following the downstream path of evolution - from S＆T development to business development - and is in the early stage of R＆D-driven Innovation Cluster. Not only the development factors of DST innovation cluster were identified but the DST was compared with other internationally recognized innovation clusters. Finally, it is suggested that the business related functions should receive due attention in innovation cluster policy.

• Molecules and Cells
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• 제38권8호
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• pp.677-684
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• 2015

Osteoarthritis (OA) is one of the most prevalent forms of joint disorder, associated with a tremendous socioeconomic burden worldwide. Various non-genetic and lifestyle-related factors such as aging and obesity have been recognized as major risk factors for OA, underscoring the potential role for epigenetic regulation in the pathogenesis of the disease. OA-associated epigenetic aberrations have been noted at the level of DNA methylation and histone modification in chondrocytes. These epigenetic regulations are implicated in driving an imbalance between the expression of catabolic and anabolic factors, leading eventually to osteoarthritic cartilage destruction. Cellular senescence and metabolic abnormalities driven by OA-associated risk factors appear to accompany epigenetic drifts in chondrocytes. Notably, molecular events associated with metabolic disorders influence epigenetic regulation in chondrocytes, supporting the notion that OA is a metabolic disease. Here, we review accumulating evidence supporting a role for epigenetics in the regulation of cartilage homeostasis and OA pathogenesis.

• BMB Reports
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• 제50권9호
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• pp.472-477
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• 2017

The transcription repressor Bach2 has been proposed as a regulator of T cell quiescence, but the underlying mechanism is not fully understood. Given the importance of interleukin-2 in T cell activation, we investigated whether Bach2 is a component of the network of factors that regulates interleukin-2 expression. In primary and transformed $CD4^+$ T cells, Bach2 overexpression counteracted T cell receptor/CD28- or PMA/ionomycin-driven induction of interleukin-2 expression, and silencing of Bach2 had the opposite effect. Luciferase and chromatin immunoprecipitation assays revealed that Bach2 binds to multiple Maf-recognition element-like sites on the interleukin-2 proximal promoter in a manner competitive with AP-1, and thereby represses AP-1-driven induction of interleukin-2 transcription. Thus, this study demonstrates that Bach2 is a direct repressor of the interleukin-2 gene in $CD4^+$ T cells during the immediate early phase of AP-driven activation, thereby playing an important role in the maintenance of immune quiescence in the steady state.

• KSII Transactions on Internet and Information Systems (TIIS)
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• 제16권8호
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• pp.2831-2845
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• 2022

Compared to the significant approach of project-based learning research, a data-driven design project-based learning has not reached a meaningful consensus regarding the most valid and reliable method for assessing design creativity. This article proposes an advanced information data-interactive learning system for creative design using a service design process that combines a design thinking. We propose a service framework to improve the convergence design process between students and advanced information data analysis, allowing students to participate actively in the data visualization and research using patent data. Solving a design problem by discovery and interpretation process, the Advanced information-interactive learning framework allows the students to verify the creative idea values or to ideate new factors and the associated various feasible solutions. The student can perform the patent data according to a business intelligence platform. Most of the new ideas for solving design projects are evaluated through complete patent data analysis and visualization in the beginning of the service design process. In this article, we propose to adapt advanced information data to educate the service design process, allowing the students to evaluate their own idea and define the problems iteratively until satisfaction. Quantitative evaluation results have shown that the advanced information data-driven learning system approach can improve the design project - based learning results in terms of design creativity. Our findings can contribute to data-driven project-based learning for advanced information data that play a crucial role in convergence design in related standards and other smart educational fields that are linked.