Bach2 represses the AP-1-driven induction of interleukin-2 gene transcription in CD4+ T cells |
Jang, Eunkyeong
(Laboratory of Autoimmunology, Department of Anatomy and Cell Biology, College of Medicine, Hanyang University)
Lee, Hye Rim (Laboratory of Autoimmunology, Department of Anatomy and Cell Biology, College of Medicine, Hanyang University) Lee, Geon Hee (Laboratory of Autoimmunology, Department of Anatomy and Cell Biology, College of Medicine, Hanyang University) Oh, Ah-Reum (Department of Biochemistry, Lee Gil Ya Cancer and Diabetes Institute, Gachon University) Cha, Ji-Young (Department of Biochemistry, Lee Gil Ya Cancer and Diabetes Institute, Gachon University) Igarashi, Kazuhiko (Department of Biochemistry, Tohoku University Graduate School of Medicine) Youn, Jeehee (Laboratory of Autoimmunology, Department of Anatomy and Cell Biology, College of Medicine, Hanyang University) |
1 | Muto A, Tashiro S, Tsuchiya H et al (2002) Activation of Maf/AP-1 repressor Bach2 by oxidative stress promotes apoptosis and its interaction with promyelocytic leukemia nuclear bodies. J Biol Chem 277, 20724-20733 DOI |
2 | Lesniewski ML, Haviernik P, Weitzel R et al (2008) Regulation of IL-2 expression by transcription factor BACH2 in umbilical cord blood CD4+ T cells. Leukemia 22, 2201-2207 DOI |
3 | International Multiple Sclerosis Genetics C, Wellcome Trust Case Control C, Sawcer S et al (2011) Genetic risk and a primary role for cell-mediated immune mechanisms in multiple sclerosis. Nature 476, 214-219 DOI |
4 | Ferreira MA, Matheson MC, Duffy DL et al (2011) Identification of IL6R and chromosome 11q13. 5 as risk loci for asthma. Lancet 378, 1006-1014 DOI |
5 | Franke A, McGovern DP, Barrett JC et al (2010) Genomewide meta-analysis increases to 71 the number of confirmed Crohn's disease susceptibility loci. Nat Genet 42, 1118-1125 DOI |
6 | Cooper JD, Smyth DJ, Smiles AM et al (2008) Meta-analysis of genome-wide association study data identifies additional type 1 diabetes risk loci. Nat Genet 40, 1399-1401 DOI |
7 | Choi YS, Gullicksrud JA, Xing S et al (2015) LEF-1 and TCF-1 orchestrate T(FH) differentiation by regulating differentiation circuits upstream of the transcriptional repressor Bcl6. Nat Immunol 16, 980-990 DOI |
8 | Choi YB, Kim CK and Yun Y (1999) Lad, an adapter protein interacting with the SH2 domain of p56lck, is required for T cell activation. J Immunol 163, 5242-5249 |
9 | Chen R, Belanger S, Frederick MA et al (2014) In vivo RNA interference screens identify regulators of antiviral and T cell differentiation. Immunity 41, 325-338 DOI |
10 | Oh Y-K, Jang E, Paik D-J and Youn J (2015) Early growth response-1 plays a non-redundant role in the differentiation of B cells into plasma cells. Immune Netw 15, 161-166 DOI |
11 | Cho WS, Jang E, Kim H-Y and Youn J (2016) Interleukin 17-expressing innate synovial cells drive K/BxN seruminduced arthritis. Immune Netw 16, 366-372 DOI |
12 | Na HH, Noh HJ, Cheong HM, Kang Y and Kim KC (2016) SETDB1 mediated FosB expression increases the cell proliferation rate during anticancer drug therapy. BMB Rep 49, 238-243 DOI |
13 | Williams TM, Moolten D, Burlein J et al (1991) Identification of a zinc finger protein that inhibits IL-2 gene expression. Science 254, 1791-1794 DOI |
14 | Jeong Y-S, Kim D, Lee YS et al (2011) Integrated expression profiling and genome-wide analysis of ChREBP targets reveals the dual role for ChREBP in glucoseregulated gene expression. PloS One 6, e22544 DOI |
15 | Siegel JP, Sharon M, Smith PL and Leonard WJ (1987) The IL-2 receptor beta chain (p70): role in mediating signals for LAK, NK, and proliferative activities. Science 238, 75-78 DOI |
16 | Mingari MC, Gerosa F, Carra G et al (1984) Human interleukin-2 promotes proliferation of activated B cells via surface receptors similar to those of activated T cells. Nature 312, 641-643 DOI |
17 | Liao W, Lin JX, Wang L, Li P and Leonard WJ (2011) Modulation of cytokine receptors by IL-2 broadly regulates differentiation into helper T cell lineages. Nat Immunol 12, 551-559 |
18 | Liao W, Lin JX and Leonard WJ (2013) Interleukin-2 at the crossroads of effector responses, tolerance, and immunotherapy. Immunity 38, 13-25 DOI |
19 | Pavan Kumar P, Purbey PK, Sinha CK et al (2006) Phosphorylation of SATB1, a global gene regulator, acts as a molecular switch regulating its transcriptional activity in vivo. Mol Cell 22, 231-243 DOI |
20 | Martins GA, Cimmino L, Liao J, Magnusdottir E and Calame K (2008) Blimp-1 directly represses Il2 and the Il2 activator Fos, attenuating T cell proliferation and survival. J Exp Med 205, 1959-1965 DOI |
21 | Oyake T, Itoh K, Motohashi H et al (1996) Bach proteins belong to a novel family of BTB-basic leucine zipper transcription factors that interact with MafK and regulate transcription through the NF-E2 site. Mol Cell Biol 16, 6083-6095 DOI |
22 | Muto A, Tashiro S, Nakajima O et al (2004) The transcriptional programme of antibody class switching involves the repressor Bach2. Nature 429, 566-571 DOI |
23 | Roychoudhuri R, Clever D, Li P et al (2016) BACH2 regulates CD8+ T cell differentiation by controlling access of AP-1 factors to enhancers. Nat immunol 17, 851-860 DOI |
24 | Muto A, Ochiai K, Kimura Y et al (2010) Bach2 represses plasma cell gene regulatory network in B cells to promote antibody class switch. EMBO J 29, 4048-4061 DOI |
25 | Roychoudhuri R, Hirahara K, Mousavi K et al (2013) BACH2 represses effector programs to stabilize T(reg)- mediated immune homeostasis. Nature 498, 506-510 DOI |
26 | Tsukumo S, Unno M, Muto A et al (2013) Bach2 maintains T cells in a naive state by suppressing effector memory-related genes. Proc Natl Acad Sci U S A 110, 10735-10740 DOI |
27 | Kim EH, Gasper DJ, Lee SH, Plisch EH, Svaren J and Suresh M (2014) Bach2 regulates homeostasis of Foxp3+ regulatory T cells and protects against fatal lung disease in mice. J Immunol 192, 985-995 DOI |