• BMB Reports
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• 제45권5호
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• pp.265-274
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• 2012

Lignin hydrolysates contain many different chemical species, including ferulic acid, coumaric acid, vanillic acid, vanillin, syringaldehyde and furfural. From the perspective of biofuels, these compounds are problematic and can cause downstream loss of product if not removed prior to beginning the fermentative process. In contrast, a search for these compounds within the literature turns up many papers where the same compounds have beneficial properties pertaining to human health, including as antioxidants and in cancer prevention, or are involved in bacterial cell-to-cell signaling. Consequently, this article reviews the dual nature of these and other compounds found in lignin hydrolysates, highlighting both their detrimental and beneficial activities.

• 대한산업공학회지
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• 제37권4호
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• pp.271-278
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• 2011

This paper is to review and organize performance strategies, issues, and measures for the efficient operation of order picking function. Order picking is the process of retrieving items from storage to meet a specific customer order, which is known to be the most labor-intensive and costly function among all the warehouse functions. This function is also important in that it has a critical impact on downstream customer service. For understanding the background of order picking and related performance issues, we will briefly introduce warehousing functions. Then we will introduce material handling within a warehouse and order picking strategies. Lastly, we will discuss about performance issues and measures in the domain of order picking operations. Productive and quality measures will be reviewed in more detail.

• 대한기계학회논문집B
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• 제21권4호
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• pp.503-508
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• 1997

The change of the structure of homogeneous turbulence subject to irrotational strains has been studied in an anti-Morel type diffuser (center matched cubic contour) using the hot wire anemometry. It was observed that the profiles of mean velocities and turbulence velocities along the center line were stable at the entrance region but rapidly changed near the matching point. The wall induced turbulence at the entrance region grows fast and was diffused toward the center at downstream. It was also observed that the axial turbulence grows faster than the radial one in the middle region of the diffusing flow and that the diffusing process has the vortex compression mechanism due to the conservation of angular momentum. These phenomena are frequently observed at the initial flow region of the free jet.

• 유체기계공업학회:학술대회논문집
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• 유체기계공업학회 2005년도 연구개발 발표회 논문집
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• pp.173-177
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• 2005

The heat/mass transfer characteristics on the plane tip surface of a high-turning first-stage turbine rotor blade has been investigated by employing the naphthalene sublimation technique. The heat/mass transfer coefficient is measured for four tip clearance height-to-chord ratios of h/c = 1.0%, 2.0%, 3.0%, and 4% at the Reynolds number of $2.09{\times}105$. The result shows that at lower h/c, there exists a strong flow separation/re-attachment process, which results in severe thermal load along the pressure-side comer. As h/c increases, the re-attachment is occurred further downstream of the pressure-side comer with lower thermal load. At higher h/c, a pair of vortices on the tip surface near the leading edge are found along the pressure-side and suction-side comers, and the pressure-side tip vortex have significant influence even on the mid-chord local heat transfer.

• 대한조선학회논문집
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• 제40권6호
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• pp.58-68
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• 2003

Despite the availability of 3D CAD systems, the designers in shipyards still use 2D CAD systems because of the need to produce drawings rapidly and a shortage of labor. The design information of ship structure contained in 2D drawings is represented by symbols that are well known among designers in shipyard. The shapes of symbols are recognized by analysis of experienced and knowledgeable designers. We propose a method for automatic recognition of 2D symbols and extraction of design information from the midship drawings. The shape and rationale of 20 symbols used in ship design have been analyzed, and symbols have been classified according to the analysis. Based on the classified symbols, the developed system recognizes the symbols expressed in 2D drawings. The meaningless geometric shape is translated into the design information including designer's intents. The extracted design data can be applied to the downstream design process in shipyards, and the 3D ship model can be automatically created.

• 대한기계학회논문집B
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• 제33권8호
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• pp.589-595
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• 2009

The instability wave formed near nozzle region grows to vortex with large scale in downstream region of spray. It plays an important role in the fuel-air mixing, combustion process and engine exhaust emissions in direct injection diesel engine. The objective of this study is to analyze effect of variant parameters (injection pressure, ambient gas density, etc.) and fuel properties on spray instability near nozzle region. Spray structure near nozzle region was investigated using a magnification photograph. A pulsed Nd-YAG laser was used as a light source, and image was taken by CCD camera. The following conclusions are drawn from this experimental analysis. In low ambient density, the effect of fuel properties on spray instability near nozzle region is dominant. In high ambient density, the effect of ambient gas on spray instability near nozzle region is dominant. High jet velocity has strong influence on spray instability.

• IMMUNE NETWORK
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• 제13권1호
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• pp.1-9
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• 2013

Autophagy is a fundamental cellular process in eukaryotic cells for maintaining homeostasis by degrading cellular proteins and organelles. Recently, the roles of autophagy have been expanded to immune systems, which in turn modulate innate immune responses. More specifically, autophagy acts as a direct effector for protection against pathogens, as well as a modulator of pathogen recognition and downstream signaling in innate immune responses. In addition, autophagy controls autoimmunity and inflammatory disorders by negative regulation of immune signaling. In this review, we focus on recent advances in the role of autophagy in innate immune systems.

• 물과 미래
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• 제17권2호
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• pp.125-131
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• 1984

watershed Model by mathematical formulation is one of the powerful tool to analyze the hydrologic process in a watershed. The seasonal watershed model is one of the mathematial model from which the monthly streamflow can be simulated and forcasted for given precipitaion data. This model also enables us to compute the monthly runoff at each subbgasin when the basin is subdivided into several small subbasins. The computation of runoff volume makes a Prediction of the areal distirbution of runoff volume for a given precipitation data. Several basins in Han River basin were chosen to simulate the monthly runoff and compute the runoff at each subbasin. A simple logarithmic regression were conducted between runoff ratio and area ratio. The correlation was very high and the equation can be used for prediciting flood volume when flood at downstream gaging station is know.

• Molecules and Cells
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• 제27권2호
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• pp.211-215
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• 2009

Toll-like receptors (TLRs) play a critical role in sensing microbial components and inducing innate immune and inflammatory responses by recognizing invading microbial pathogens. Lipopolysaccharide-induced dimerization of TLR4 is required for the activation of downstream signaling pathways including nuclear factor-kappa B ($NF-{\kappa}B$). Therefore, TLR4 dimerization may be an early regulatory event in activating ligand-induced signaling pathways and induction of subsequent immune responses. Here, we report biochemical evidence that 6-shogaol, the most bioactive component of ginger, inhibits lipopolysaccharide-induced dimerization of TLR4 resulting in the inhibition of $NF-{\kappa}B$ activation and the expression of cyclooxygenase-2. Furthermore, we demonstrate that 6-shogaol can directly inhibit TLR-mediated signaling pathways at the receptor level. These results suggest that 6-shogaol can modulate TLR-mediated inflammatory responses, which may influence the risk of chronic inflammatory diseases.

• 기술혁신학회지
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• 제7권2호
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• pp.373-395
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• 2004

In year 2003, the Daedeok Science Town(DST) has celebrated its 30 years of anniversary and achievement in science and technology development. However, there is a criticism that DST has not played its expected role in Korea's National Innovation System. Recognizing this criticism, the development of DST was evaluated in the perspective of innovation cluster. The research shows that DST has been following the downstream path of evolution - from S＆T development to business development - and is in the early stage of R＆D-driven Innovation Cluster. Not only the development factors of DST innovation cluster were identified but the DST was compared with other internationally recognized innovation clusters. Finally, it is suggested that the business related functions should receive due attention in innovation cluster policy.