1 |
Klionsky, D. J. and S. D. Emr. 2000. Autophagy as a regulated pathway of cellular degradation. Science 290: 1717- 1721.
DOI
|
2 |
Mizushimam, N. and D. J. Klionsky. 2007. Protein turnover via autophagy: implications for metabolism. Annu. Rev. Nutr. 27: 19-40.
DOI
|
3 |
Massey, A. C., C. Zhang, and A. M. Cuervo. 2006. Chaperone- mediated autophagy in aging and disease. Curr. Top. Dev. Biol. 73: 205-235.
DOI
|
4 |
Cuervo, A. M. and J. H. Dice. 2000. Unique properties of lamp2a compared to other lamp2 isoforms. J. Cell Sci. 113 Pt24: 4441-4450.
|
5 |
Cuervo, A. M. and J. F. Dice. 1996. A receptor for the selective uptake and degradation of proteins by lysosomes. Science 273: 501-503.
DOI
|
6 |
Chiang, H. L., S. R. Terlecky, C. P. Plant, and J. F. Dice. 1989. A role for a 70-kilodalton heat shock protein in lysosomal degradation of intracellular proteins. Science 246: 382-385
DOI
|
7 |
Mizushima, N., Y. Ohsumi, and T. Yoshimori. 2002. Autophagosome formation in mammalian cells. Cell Struct. Funct. 27: 421-429.
DOI
|
8 |
Johansen, T. and T. Lamark. 2011. Selective autophagy mediated by autophagic adapter proteins Autophagy.7: 279-296.
DOI
|
9 |
Mizushima, N., T. Noda, T. Yoshimori, Y. Tanaka, T. Ishii, M. D. George, D. J. Klionsky, M. Ohsumi, and Y. Ohsumi. 1998. A protein conjugation system essential for autophagy. Nature 395: 395-398.
DOI
|
10 |
Ohsumi, Y. 2001. Molecular dissection of autophagy: two ubiquitin-like systems. Nat. Rev. Mol. Cell Biol. 2: 211-216.
DOI
|
11 |
Bjorkoy, G., T. Lamark, A. Brech, H. Outzen, M. Perander, A. Overvatn, H. Stenmark, and T. Johansen. 2005. p62/SQSTM1 forms protein aggregates degraded by autophagy and has a protective effect on huntingtin-induced cell death. J. Cell Biol. 171: 603-614.
DOI
|
12 |
Levine, B. and D. J. Klionsky. 2004. Development by self-digestion: molecular mechanisms and biological functions of autophagy. Dev. Cell 6: 463-477.
DOI
|
13 |
Levine, B. and G. Kroemer. 2008. Autophagy in the pathogenesis of disease. Cell 132: 27-42.
DOI
|
14 |
Shintani, T. and D. J. Klionsky. 2004. Autophagy in health and disease: a double-edged sword. Science 306: 990-995.
DOI
|
15 |
Nakagawa, I., A. Amano, N. Mizushima, A. Yamamoto, H. Yamaguchi, T. Kamimoto, A. Nara, J. Funao, M. Nakata, K. Tsuda, S. Hamada, and T. Yoshimori. 2004. Autophagy defends cells against invading group A Streptococcus. Science 306: 1037-1040.
DOI
|
16 |
Gutierrez, M. G., S. S. Master, S. B. Singh, G. A. Taylor, M. I. Colombo, and V. Deretic. 2004. Autophagy is a defense mechanism inhibiting BCG and Mycobacterium tuberculosis survival in infected macrophages. Cell 119: 753-766.
DOI
|
17 |
Xu, Y., C. Jagannath, X. D. Liu, A. Sharafkhaneh, K. E. Kolodziejska, and N. T. Eissa. 2007. Toll-like receptor 4 is a sensor for autophagy associated with innate immunity. Immunity 27: 135-144.
DOI
|
18 |
Delgado, M. A., R. A. Elmaoued, A. S. Davis, G. Kyei, and V. Deretic. 2008. Toll-like receptors control autophagy. EMBO J. 27: 1110-1121.
DOI
|
19 |
Sanjuan, M. A., C. P. Dillon, S. W. Tait, S. Moshiach, F. Dorsey, S. Connell, M. Komatsu, K. Tanaka, J. L. Cleveland, S. Withoff, and D. R. Green. 2007. Toll-like receptor signalling in macrophages links the autophagy pathway to phago cytosis. Nature 450: 1253-1257.
DOI
|
20 |
Saitoh, T., N. Fujita, M. H. Jang, S. Uematsu, B. G. Yang, T. Satoh, H. Omori, T. Noda, N. Yamamoto, M. Komatsu, K. Tanaka, T. Kawai, T. Tsujimura, O. Takeuchi, T. Yoshimori, and S. Akira. 2008. Loss of the autophagy protein Atg16L1 enhances endotoxin-induced IL-1beta production. Nature 456: 264-268.
DOI
|
21 |
Dengjel, J., O. Schoor, R. Fischer, M. Reich, M. Kraus, M. Muller, K. Kreymborg, F. Altenberend, J. Brandenburg, H. Kalbacher, R. Brock, C. Driessen, H. G. Rammensee, and S. Stevanovic. 2005. Autophagy promotes MHC class II presentation of peptides from intracellular source proteins. Proc. Natl. Acad. Sci. U. S. A. 102: 7922-7927.
DOI
|
22 |
Pua, H. H. and Y. W. He. 2007. Maintaining T lymphocyte homeostasis: another duty of autophagy. Autophagy 3: 266-267
DOI
|
23 |
Paludan, C., D. Schmid, M. Landthaler, M. Vockerodt, D. Kube, T. Tuschl, and C. Münz. 2005. Endogenous MHC class II processing of a viral nuclear antigen after autophagy. Science 307: 593-596.
DOI
|
24 |
Schmid, D., M. Pypaert, and C. Münz. 2007. Antigen-loading compartments for major histocompatibility complex class II molecules continuously receive input from autophagosomes. Immunity 26: 79-92.
DOI
|
25 |
Pua, H. H., I. Dzhagalov, M. Chuck, N. Mizushima, and Y. W. He. 2007. A critical role for the autophagy gene Atg5 in T cell survival and proliferation. J. Exp. Med. 204: 25-31.
DOI
|
26 |
Miller, B. C., Z. Zhao, L. M. Stephenson, K. Cadwell, H. H. Pua, H. K. Lee, N. N. Mizushima, A. Iwasaki, Y. W. He, W. Swat, H. W. Virgin, 4th. 2008. The autophagy gene ATG5 plays an essential role in B lymphocyte development. Autophagy 4: 309-314.
DOI
|
27 |
Schmid, D. and C. Münz. 2007. Innate and adaptive immunity through autophagy. Immunity 27: 11-21.
DOI
|
28 |
Yuk, J. M., D. M. Shin, H. M. Lee, C. S. Yang, H. S. Jin, K. K. Kim, Z. W. Lee, S. H. Lee, J. M. Kim, and E. K. Jo. 2009. Vitamin D3 induces autophagy in human monocytes/ macrophages via cathelicidin. Cell Host Microbe 6: 231-243.
DOI
|
29 |
Watson, R. O., P. S. Manzanillo, and J. S. Cox. 2012. Extracellular M. tuberculosis DNA targets bacteria for autophagy by activating the host DNA-sensing pathway. Cell 150: 803-815.
DOI
|
30 |
Mahairas, G. G., P. J. Sabo, M. J. Hickey, D. C. Singh, and C. K. Stover. 1996. Molecular analysis of genetic differences between Mycobacterium bovis BCG and virulent M. bovis. J. Bacteriol. 178: 1274-1282.
DOI
|
31 |
Pym, A. S., P. Brodin, L. Majlessi, R. Brosch, C. Demangel, A. Williams, K. E. Griffiths, G. Marchal, C. Leclerc, and S. T. Cole. 2003. Recombinant BCG exporting ESAT-6 confers enhanced protection against tuberculosis. Nat. Med. 9: 533-
DOI
|
32 |
Thurston, T. L., G. Ryzhakov, S. Bloor, N. von Muhlinen, and F. Randow. 2009. The TBK1 adaptor and autophagy receptor NDP52 restricts the proliferation of ubiquitin-coated bacteria. Nat. Immunol. 10: 1215-1221.
DOI
|
33 |
Smith, J., J. Manoranjan, M. Pan, A. Bohsali, J. Xu, J. Liu, K. L. McDonald, A. Szyk, N. LaRonde-LeBlanc, and L. Y. Gao. 2008. Evidence for pore formation in host cell membranes by ESX-1-secreted ESAT-6 and its role in Mycobacterium marinum escape from the vacuole. Infect. Immun. 76: 5478-5487.
DOI
|
34 |
Rich, K. A., C. Burkett, and P. Webster. 2003. Cytoplasmic bacteria can be targets for autophagy. Cell. Microbiol. 5: 455-468.
DOI
|
35 |
Zheng, Y. T., S. Shahnazari, A. Brech, T. Lamark, T. Johansen, and J. H. Brumell. 2009. The adaptor protein p62/SQSTM1 targets invading bacteria to the autophagy pathway. J. Immunol. 183: 5909-5916.
DOI
|
36 |
Yuk, J. M., T. Yoshimori, and E. K. Jo. 2012. Autophagy and bacterial infectious diseases. Exp. Mol. Med. 44: 99-108.
DOI
|
37 |
Iwasaki, A. and R. Medzhitov. 2004. Toll-like receptor control of the adaptive immune responses. Nat. Immunol. 5: 987-995.
DOI
|
38 |
Oh, J. E. and H. K. Lee. 2012. Modulation of pathogen recognition by autophagy. Front Immunol. 3: 44.
|
39 |
Lee, M. S. and Y. J. Kim. 2007. Signaling pathways downstream of pattern-recognition receptors and their cross talk. Annu. Rev. Biochem. 76: 447-480.
DOI
|
40 |
Cooney, R., J. Baker, O. Brain, B. Danis, T. Pichulik, P. Allan, D. J. Ferguson, B. J. Campbell, D. Jewell, and A. Simmons. 2010. NOD2 stimulation induces autophagy in dendritic cells influencing bacterial handling and antigen presentation. Nat. Med. 16: 90-97.
DOI
|
41 |
Travassos, L. H., L. A. Carneiro, M. Ramjeet, S. Hussey, Y. G. Kim, J. G. Magalhaes, L. Yuan, F. Soares, E. Chea, L. Le Bourhis, I. G. Boneca, A. Allaoui, N. L. Jones, G. Nunez, S. E. Girardin, and D. J. Philpott. 2010. Nod1 and Nod2 direct autophagy by recruiting ATG16L1 to the plasma membrane at the site of bacterial entry. Nat. Immunol. 11: 55-62.
DOI
|
42 |
Liang, X. H., L. K. Kleeman, H. H. Jiang, G. Gordon, J. E. Goldman, G. Berry, B. Herman, and B. Levine. 1998. Protection against fatal Sindbis virus encephalitis by beclin, a novel Bcl-2-interacting protein. J. Virol. 72: 8586-8596.
|
43 |
Cho, J. H. and C. T. Weaver. 2007. The genetics of inflammatory bowel disease. Gastroenterology 133: 1327-1339.
DOI
|
44 |
Hampe, J., A. Franke, P. Rosenstiel, A. Till, M. Teuber, K. Huse, M. Albrecht, G. Mayr, F. M. De La Vega, J. Briggs, S. Gunther, N. J. Prescott, C. M. Onnie, R. Hasler, B. Sipos, U. R. Folsch, T. Lengauer, M. Platzer, C. G. Mathew, M. Krawczak, and S. Schreiber. 2007. A genome-wide association scan of nonsynonymous SNPs identifies a susceptibility variant for Crohn disease in ATG16L1. Nat. Genet. 39: 207-211
DOI
|
45 |
Rioux, J. D., R. J. Xavier, K. D. Taylor, M. S. Silverberg, P. Goyette, A. Huett, T. Green, P. Kuballa, M. M. Barmada, L. W. Datta, Y. Y. Shugart, A. M. Griffiths, S. R. Targan, A. F. Ippoliti, E. J. Bernard, L. Mei, D. L. Nicolae, M. Regueiro, L. P. Schumm, A. H. Steinhart, J. I. Rotter, R. H. Duerr, J. H. Cho, M. J. Daly, and S. R. Brant. 2007. Genome-wide association study identifies new susceptibility loci for Crohn disease and implicates autophagy in disease pathogenesis. Nat. Genet. 39: 596-604.
DOI
|
46 |
Orvedahl, A., S. MacPherson, R. Sumpter, Jr, Z. Tallóczy, Z. Zou, and B. Levine. 2010. Autophagy protects against Sindbis virus infection of the central nervous system. Cell Host Microbe 7: 115-127.
DOI
|
47 |
Orvedahl, A., D. Alexander, Z. Tallóczy, Q. Sun, Y. Wei, W. Zhang, D. Burns, D. A. Leib, and B. Levine. 2007. HSV-1 ICP34.5 confers neurovirulence by targeting the Beclin 1 autophagy protein. Cell Host Microbe 1: 23-35.
DOI
|
48 |
Alexander, D. E. and D. A. Leib. 2008. Xenophagy in herpes simplex virus replication and pathogenesis. Autophagy 4: 101-103.
DOI
|
49 |
Barton, G. M. 2007. Viral recognition by Toll-like receptors. Semin. Immunol. 19: 33-40.
DOI
|
50 |
Lee, H. K. and A. Iwasaki. 2008. Autophagy and antiviral immunity. Curr. Opin. Immunol. 20: 23-29.
DOI
|
51 |
Tal, M. C. and A. Iwasaki. 2009. Autophagy and innate recognition systems. Curr. Top. Microbiol. Immunol. 335: 107-121
|
52 |
Foy, E., K. Li, R. Sumpter, Jr, Y. M. Loo, C. L. Johnson, C. Wang, P. M. Fish, M. Yoneyama, T. Fujita, S. M. Lemon, M. Gale, Jr. 2005. Control of antiviral defenses through hepatitis C virus disruption of retinoic acid-inducible gene-I signaling. Proc. Natl. Acad. Sci. U. S. A. 102: 2986-2991.
DOI
|
53 |
Yordy, B. and A. Iwasaki. 2011. Autophagy in the control and pathogenesis of viral infection. Curr. Opin. Virol. 1: 196-203.
DOI
|
54 |
Yoneyama, M., M. Kikuchi, T. Natsukawa, N. Shinobu, T. Imaizumi, M. Miyagishi, K. Taira, S. Akira, and T. Fujita. 2004. The RNA helicase RIG-I has an essential function in double-stranded RNA-induced innate antiviral responses. Nat. Immunol. 5: 730-737.
DOI
|
55 |
Yoneyama, M., M. Kikuchi, K. Matsumoto, T. Imaizumi, M. Miyagishi, K. Taira, E. Foy, Y. M. Loo, M. Gale, Jr, S. Akira, S. Yonehara, A. Kato, and T. Fujita. 2005. Shared and unique functions of the DExD/H-box helicases RIG-I, MDA5, and LGP2 in antiviral innate immunity. J. Immunol. 175: 2851- 2858.
DOI
|
56 |
Jounai, N., F. Takeshita, K. Kobiyama, A. Sawano, A. Miyawaki, K. Q. Xin, K. J. Ishii, T. Kawai, S. Akira, K. Suzuki, and K. Okuda. 2007. The Atg5 Atg12 conjugate associates with innate antiviral immune responses. Proc. Natl. Acad. Sci. U. S. A. 104: 14050-14055.
DOI
|
57 |
Tal, M. C., M. Sasai, H. K. Lee, B. Yordy, G. S. Shadel, and A. Iwasaki. 2009. Absence of autophagy results in reactive oxygen species-dependent amplification of RLR signaling. Proc. Natl. Acad. Sci. U. S. A. 106: 2770-2775.
DOI
|
58 |
Schroder, K. and J. Tschopp. 2010. The inflammasomes. Cell 140: 821-832.
DOI
|
59 |
Shi, C. S., K. Shenderov, N. N. Huang, J. Kabat, M. Abu-Asab, K. A. Fitzgerald, A. Sher, and J. H. Kehrl. 2012. Activation of autophagy by inflammatory signals limits IL-1 production by targeting ubiquitinated inflammasomes for destruction. Nat. Immunol. 13: 255-263.
DOI
|
60 |
Bodemann, B. O., A. Orvedahl, T. Cheng, R. R. Ram, Y. H. Ou, E. Formstecher, M. Maiti, C. C. Hazelett, E. M. Wauson, M. Balakireva, J. H. Camonis, C. Yeaman, B. Levine, and M. A. White. 2011. RalB and the exocyst mediate the cellular starvation response by direct activation of autophagosome assembly. Cell 144: 253-267.
DOI
|