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An Approach of Ecological Niche to Analysis of Recognition of 5th Grade Elementary students for Conception of Photosynthesis (생태 지위적 접근을 통한 5학년의 광합성 개념 분석)

  • Jeong, Jae-Hoon;Kim, Young-Shin
    • Journal of The Korean Association For Science Education
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    • v.31 no.4
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    • pp.513-527
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    • 2011
  • There have been studies about conceptual ecology making a profound study of conceptual changes in learners' cognitive structure. Because learners' cognitive structure have been compared to ecology, it is natural to think that conception in learner's cognitive structure have a niche as species in ecology have niches. Therefore, it is necessary to study niche approach about conception that learners recognize in their cognitive structure. The purposes of this study were to identify relationships among conceptions that 5th grade elementary school students recognize about photosynthesis and to identify how these relationships among conceptions about photosynthesis change before and after a class of photosynthesis in curriculum in terms of an approach of ecological niche which are composed of 3 domains - diversity of conceptions, relevance and frequency rate of conceptions, and competition among conceptions. Open ended questionnaire was developed by 4 fields: photosynthetic place, photosynthetic products, photosynthetic materials needed and environment factors of photosynthesis. The subjects sampled in this study were 310 5th grade elementary students in 5 cites. Before and after classes in photosynthesis in science curriculum, students were asked to write down conceptions that they knew about the 4 fields of photosynthesis of questionnaire and to write down scales of relevance from 1 to 30 about how they think the conceptions are related to the field of photosynthesis. The results of this study showed the following: First, most students have had a variety of conceptions and commonly recognized 'light' and 'water' as concepts in photosynthesis. Second, students still recognized their preconceptions like 'soil' and 'root,' etc. that were far from scientific conceptions of photosynthesis although they took classes in photosynthesis. Third, students needed to take the various strategies of teachers because they did not recognized scientific conceptions appropriately about photosynthetic fields. Fourth, it appeared that photosynthetic conceptions recognized by students had status in terms of relevance and frequency rate of conceptions, and competition among conceptions, and that they looked like the niche of conceptions in their conceptual ecologies.

External Beam Radiotherapy in the Management of Low Grade Astrocytoma of the Brain (뇌 성상세포종 환자의 외부 방사선치료)

  • Chun, Ha-Chung
    • Radiation Oncology Journal
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    • v.27 no.1
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    • pp.23-28
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    • 2009
  • Purpose: This study was designed to evaluate the effectiveness of postoperative radiotherapy for patients with low-grade astrocytomas and to define an optimal radiotherapeutic regimen and prognostic factors. Materials and Methods: A total of 69 patients with low-grade astrocytomas underwent surgery and postoperative radiotherapy immediately following surgery at our institution between October 1989 and September 2006. The median patient age was 36 years. Forty-one patients were 40 years or younger and 28 patients were 41 years or older. Fourteen patients underwent a biopsy alone and the remaining 55 patients underwent a subtotal resection. Thirty-nine patients had a Karnofsky performance status of less than 80% and 30 patients had a Karnofsky performance status greater than 80%. Two patients were treated with whole brain irradiation followed by a coned down boost field to the localized area. The remaining 67 patients were treated with a localized field with an appropriate margin. Most of the patients received a dose of $50\sim55$ Gy and majority of the patients were treated with a dose of 54 Gy. Results: The overall 5-year and 7-year survival rates for all of the 69 patients were 49% and 44%, respectively. Corresponding disease free survival rates were 45% and 40%, respectively. Patients who underwent a subtotal resection showed better survival than patients who underwent a biopsy alone. The overall 5-year survival rates for patients who underwent a subtotal resection and patients who underwent a biopsy alone were 57% and 38%, respectively (p<0.05). Forty-one patients who were 40 years or younger showed a better overall 5-year survival rate as compared with 28 patients who were 41 years or older (56% versus 40%, p<0.05). The overall 5-year survival rates for 30 patients with a Karnofsky performance status greater than 80% and 39 patients with a Karnofsky performance status less than 80% were 51% and 47%, respectively. This finding was not statistically significant. Although one patient was not able to complete the treatment because of neurological deterioration, there were no significant treatment related toxicities. Conclusion: Postoperative radiotherapy following surgery is a safe and effective treatment for patients with low-grade astrocytomas. The extent of surgery and age were noted as significant prognostic factors in this study. However, further effective treatment might be necessary in the future to improve long-term survival rates.

The Effects of Organization Characteristics and Relationship Characteristics on Relational Performance: Focused on Mediating Effects of the Dimensions of Trust and Commitment (조직특성과 관계특성이 관계성과에 미치는 영향: 신뢰 차원과 결속 차원의 매개효과를 중심으로)

  • Sung, Min;Oh, Se-Jo
    • Journal of Distribution Research
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    • v.12 no.1
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    • pp.1-31
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    • 2007
  • While trust and commitment are core mediating variables for the purpose of maintaining the long-term relationship, in the context of the characteristics of company and the relationship performance of its members, there have been limited studies which explore as to how each of the dimensions has affects differently. The basic purpose of this study is to examine the relationship between an automobile manufacturer and its agencies. The main purpose of this study is to examine how each different dimension of trust and commitment on the automobile manufacturer has different mediating effects between the characteristics of company(organization characteristics, relationship characteristics) and relationship performance perceived by its agents. Another purpose is to investigate the mechanism by which the relationship performance of the agencies is improved. An empirical study surveying 115 sales office managers at a leading automobile manufacturer in Korea was conducted. An analysis of the collected data indicates that while the characteristics of company have a positive influence on the agencies' relational performance through the mediating role of both trust of benevolence and commitment, agencies' trust of their headquarter's benevolence has a different influence on the dimensions of commitment. Finally, the authors discussed some theoretical contributions and managerial implications. And then, they presented limitations of this study and the future research directions.

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Shaking Table Test for Seismic Performance Evaluation of Non-Seismic Designed Wall-Type Apartment (내진설계 되지 않은 공동주택의 진동대 실험에 의한 내진성능 평가)

  • Chung, Lan;Lee, Joung-Woo;Park, Tae-Won
    • Journal of the Korea Concrete Institute
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    • v.18 no.6 s.96
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    • pp.721-728
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    • 2006
  • Earthquakes are reported thai building structures have been colossal damaged, but before 1988 designed structures which were not applicate seismic design code have no seismic performance. Especially, for the apartment structures were indicated that it have no resist wall element of earthquake before 1988 designed structures. We have to evaluate for seismic performance this structures, therefore it will be retrofitted for seismic index sufficient structures. We performed seismic performance evaluation for model structures by MIDAS which is general structure analysis software. In this study, it was performed shaking table test to evaluate model structure which is reinforcement concrete and 5 floors for seismic performance index. We made specimens by similar's law and tested shaking table test. In the shaking table test it is not performed prototype model test because of space and equipment condition. So we had made scale-down model for 1/5 by similar's law. That's why it needs for the evaluation of performance. However, it is not possible to do an experiment of prototype owing to the shortage of space and the limit of an experimental instrument in the shaking table test. Then, modeling and reducing the part of prototype do the experiment. In this experiment a shaking table test is done and seismic performance of model structures is evaluated by using similitude laws for scale down specimen. As a result it is proved that non-seismic design structures need to retrofit since seismic performance shows life safe grade in 0.12g of an earthquake.

Forensic Decision of Median Filtering Image Using a Coefficient of Variation of Fourier Transform (Fourier 변환 변이계수를 이용한 미디언 필터링 영상의 포렌식 판정)

  • RHEE, Kang Hyeon
    • Journal of the Institute of Electronics and Information Engineers
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    • v.52 no.8
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    • pp.67-73
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    • 2015
  • In a distribution of digital image, there is a serious problem that is the image alteration by a forger. For the problem solution, this paper proposes the forensic decision algorithm of a median filtering (MF) image using the feature vector based on a coefficient of variation (c.v.) of Fourier transform. In the proposed algorithm, we compute Fourier transform (FT) coefficients of row and column line respectively of an image first, then c.v. between neighboring lines is computed. Subsquently, 10 Dim. feature vector is defined for the MF detection. On the experiment of MF detection, the proposed scheme is compared to MFR (Median Filter Residual) and Rhee's MF detection schemes that have the same 10 Dim. feature vector both. As a result, the performance is excellent at Unaltered, JPEG (QF=90), Down scaling (0.9) and Up scaling (1.1) images, and it showed good performance at Gaussian filtering ($3{\times}3$) image. However, in the performance evaluation of all measured items of the proposed scheme, AUC (Area Under ROC (Receiver Operating Characteristic) Curve) by the sensitivity and 1-specificity approached to 1 thus, it is confirmed that the grade of the performance evaluation is rated as 'Excellent (A)'.

Exosome-derived microRNA-29c Induces Apoptosis of BIU-87 Cells by Down Regulating BCL-2 and MCL-1

  • Xu, Xiang-Dong;Wu, Xiao-Hou;Fan, Yan-Ru;Tan, Bing;Quan, Zhen;Luo, Chun-Li
    • Asian Pacific Journal of Cancer Prevention
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    • v.15 no.8
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    • pp.3471-3476
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    • 2014
  • Background: Aberrant expression of the microRNA-29 family is associated with tumorigenesis and cancer progression. As transport carriers, tumor-derived exosomes are released into the extracellular space and regulate multiple functions of target cells. Thus, we assessed the possibility that exosomes could transport microRNA-29c as a carrier and correlations between microRNA-29c and apoptosis of bladder cancer cells. Materials and Methods: A total of 28 cancer and adjacent tissues were examined by immunohistochemistry to detect BCL-2 and MCL-1 expression. Disease was Ta-T1 in 12 patients, T2-T4 in 16, grade 1 in 8, 2 in 8 and 3 in 12. The expression of microRNA-29c in cancer tissues was detected by quantitative reverse transcriptase PCR (QRT-PCR). An adenovirus containing microRNA-29c was used to infect the BIU-87 human bladder cancer cell line. MicroRNA-29c in exosomes was measured by QRT-PCR. After BIU-87 cells were induced by exosomes-derived microRNA-29c, QRT-PCR was used to detect the level of microRNA-29c. Apoptosis was examined by flow cytometry and BCL-2 and MCL-1 mRNA expressions were assessed by reverse transcription-polymerase chain reaction. Western blotting was used to determine the protein expression of BCL-2 and MCL-1. Results: The expressions of BCL-2 and MCL-1 protein were remarkably increased in bladder carcinoma (p<0.05), but was found mainly in the basal and suprabasal layers in adjacent tissues. The expression of microRNA-29c in cancer tissues was negatively correlated with the BCL-2 and MCL-1. The expression level of microRNA-29c in exosomes and BIU-87 cells from the experiment group was higher than that in control groups (p<0.05). Exosome-derived microRNA-29c induced apoptosis (p<0.01). Although only BCL-2 was reduced at the mRNA level, both BCL-2 and MCL-1 were reduced at the protein level. Conclusions: Human bladder cancer cells infected by microRNA-29c adenovirus can transport microRNA-29c via exosomes. Moreover, exosome-derived microRNA29c induces apoptosis in bladder cancer cells by down-regulating BCL-2 and MCL-1.

Honor Guards' Ceremonial and Dress by King Jung-jo Hwa-Sung Hang-Cha (정조(正租)의 화성행차(華城行次)에 나타난 의장(儀仗)과 복식(服飾)에 관(關)한 연구(硏究))

  • Lee, Hye-Young;Shim, Hwa-Jin
    • Journal of Fashion Business
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    • v.6 no.2
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    • pp.29-40
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    • 2002
  • Honor guards‘ dress represented by royal carriage parade. This thesis studies the ceremonial dress worn by the ceremonial troops during the Hwa-sung Hang-hang Ban-cha drawing (華城幸行班次圖) in the Chosun dynasty of King Jung-jo. The purpose of this study is to understand the national level ceremony by closely looking into the traditional ceremonial dress and the various signs that were used at these events thereby enhancing the cultural status of the Jung-jo King period. The Hwa-sung Hang-hang Ban-cha drawing(華城幸行班次圖) has its characteristics and also has commonality between the garments worn at these ceremonies. These garments are a traditional heritage brought down from many ages before and is a reflection of the changes that have occurred within our everyday life. Among these many records the Bancha-do(班次圖) is a representation of records that show what was worn by both nobles down to the ceremonial troops. The uniforms of the ceremonial troops were not only huge in size but also very diverse according to rank and grade. They used strong true colors with colorful flags, ceremonial items and musical instruments. These all added to the grandeur of the ceremony. The ceremonial flag was itself a symbol and was the core of the whole ceremony and parade. These ceremonial flags represented the heaven, sun, moon, hill and animals as well as supernatural gods. All these showed change in shape, color and content by age and time. Also the Yongmun Gichi(Dragon flag: 龍紋旗幟) is a supernatural being representing the power and wish of the ruler. The Chunsang-mun represents the indivisible relationship between man and heaven and also a metaphor for absolute power. A close look at ceremonial instruments show a direct representation towards power such as an axe, spear and sword and integrated with other large ceremonial items not only provided a shade but was also a representation of worship. These all were a more or less representation of authority. The musical instruments expressed the absolute authority of the ruler and maintained the marching order and also added grandeur to the parade. A summary of the ceremonial troops in the As seen above, these national ceremonies were a representation of the present power of authority and the will to rule. These ideas and the philosophy of “ruled by heaven” is represented here in the uniforms and the ceremony itself. The Bicentennial anniversary of the Nung - hang of February 1795 will be an excellent opportunity to show and inherit the tradition and recreation of our heritage. In this view we must look at the color and shape of traditional dress to be able to inherit and learn from our ancestors.

A Comparative Study for Estimation of Greenhouse Gas for Local Government`s Sustainable Transport (지속가능교통 평가를 위한 온실가스 배출량 산정 방법론의 지자체 적용 및 비교 연구)

  • Yu, Byeong-Yong;Bae, Sang-Hun;Han, Sang-Yong;Kim, Geon-Yeong
    • Journal of Korean Society of Transportation
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    • v.29 no.5
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    • pp.55-65
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    • 2011
  • In effort to estimate sustainability of the transportation sector, this study conducts a comparative analysis of methodology suggested for measuring greenhouse gas emission. There are two approaches proposed by the UN IPCC: 1) top-down approach (TDA) based on the amount oil sales, and 2) bottom-up approach (BUA) utilizing the velocity of moving source and traffic volume data. The subject areas for analysis were selected based on research results by the Korea Transportation Institute that evaluate traffic sustainability of each local government. Gwacheon-si being one of the top ranked areas in sustainability, and Anseong-si being ranked at the 7th level were analyzed. By the tier 1 methodology, Gwacheon-si and Anseong-si are estimated to create 74,813ton/yr, and 584,125ton/yr of the greenhouse gas emission, respectively. The tier 3 methodology, however, estimates Gwacheon-si and Anseong-si to create 91,462ton/yr, and 163,801ton/yr of the emission, respectively. Comparison of the two estimated emissions shows considerable differences; i.e., the tier 3 method over estimates Gwacheon-si's emission by 22.3% whereas it underestimates Anseong-si's greenhouse gas emission by the factor of about 3.5 compared to the emissions obtained from the tier 1 method. The result from this study implies that the traffic-sustainability-index based grade of each local government can be evaluated differently by the method adopted for measuring greenhouse gas emission.

Development of the Heuristic Attention Model Based on Analysis of Eye Movement of Elementary School Students on Discrimination task (변별과제에서 초등학생의 안구운동 분석을 통한 발견적 주의 모델 개발)

  • Shin, Won-Sub;Shin, Dong-Hoon
    • Journal of The Korean Association For Science Education
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    • v.33 no.7
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    • pp.1471-1485
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    • 2013
  • The purpose of this study was to develop a HAM (Heuristic Attention Model) by analyzing the difference between eye movements according to the science achievement of elementary school students on discrimination task. Science achievement was graded by the results of the Korea national achievement test conducted in 2012 for a random sampling of classes. As an assessment tool to check discrimination task, two discrimination measure problems from TSPS (Test of Science Process Skill, developed in 1994) which were suitable for an eye tracking system were adopted. The subjects of this study were 20 students from the sixth grade who agreed to participate in the research. SMI was used to collect EMD (eye movement data). Experiment 3.2 and BeGaze 3.2 programs were used to plan experiments and analyze EMD. As a result, eye movements of participants in discrimination tasks varied greatly in counts and duration of fixation, first fixation duration, and dwell time, according to students' science achievement and difficulty of the problems. By the analysis of EMD, strategies of the students' problem-solving could be found. During problem solving, subjects' eye movements were affected by visual attention; bottom-up attention, top-down attention and convert attention, and aflunter attention. In conclusion, HAM was developed, and it is believed to help in the development of a science learning program for underachievers.

The Comparison of Clinical Outcomes between GnRH Agonist Long Protocol and GnRH Antagonist Short Protocol in Oocyte Donation Cycles (난자공여를 통한 체외수정 시술에서 성선자극호르몬 유리호르몬 효능제 장기요법과 길항제 단기요법 사이의 임상 결과 비교)

  • Rhee, Jeong-Ho;Park, Joon-Chul;Kim, Jong-In
    • Clinical and Experimental Reproductive Medicine
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    • v.30 no.1
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    • pp.95-103
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    • 2003
  • Objective : To assess and compare the clinical outcomes between GnRH agonist long protocol and GnRH antagonist short protocol in oocyte donation program. Materials and Methods: Of total 18 oocyte donation cycles, controlled ovarian hyperstimulation (COH) were performed with GnRH agonist long protocol and GnRH antagonist short protocol in initial 9 cycles and later 9 cycles, respectively. Oral estradiol valerate and progesterone in oil we re administrated to all recipients for endometrial preparation. Oral estradiol administration was started from donor cycle day 1 after full shut down of gonadal axis with GnRH agonist in patients with ovarian function. Progesterone was injected from oocyte retrieval day of donor initially, then continuously till pregnancy 12 weeks if pregnancy was ongoing. We compared the parameters of clinical outcomes, such as number of the retrieved oocytes, fertilization rate, high grade embryo production rate, clinical pregnancy rate, implantation rate, ongoing pregnancy rate, COH duration, total gonadotropin dose for COH between GnRH agonist long protocol group and GnRH antagonist group. Statistical analysis was performed using Mann-Whitney test, p<0.05 was considered as statistically significant. Results: The number of retrieved oocytes, fertilization rate, high grade embryo production rate, clinical pregnancy rate, implantation rate, ongoing pregnancy rate were $14.89{\pm}7.83$, 81%, 64%, 78%, 31%, 78%, respectively in GnRHa long protocol group and $11.22{\pm}8.50$, 79%, 64%, 67%, 34%, 56%, respectively in GnRH antagonist group. There was no significant differences in parameters of clinical outcomes between 2 groups (all p value >0.05). Duration and total gonadotropin dose for COH were $10.94{\pm}1.70$ days and $43.78{\pm}6.8$ vials in 18 cycles, $12.00{\pm}1.73$ days and $48.00{\pm}6.93$ vials in agonist group, $9.88{\pm}0.78$ days and $39.55{\pm}3.13$ vials in antagonist group, respectively. In GnRH agonist long protocol group, significantly longer duration and higher gonadotropin dose for COH were needed (p=0.012). Conclusion: In oocyte donation program, clinical outcomes from controlled ovarian hyperstimulation with GnRH antagonist were comparable to those from GnRH agonist long protocol group, so controlled ovarian hyperstimulation with GnRH antagonist may be effective as GnRH agonist long protocol. At least there may not be harmful effects of GnRH antagonist on oocyte development and quality.