• Title/Summary/Keyword: Dimensional Control

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Fabrication of Multicomponent Protein Microarrays with Microfluidic Devices of Poly(dimethylsiloxane)

  • Jeon, Se-Hoon;Kim, Ui-Seong;Jeon, Won-Jin;Shin, Chee-Burm;Hong, Su-Rin;Choi, In-Hee;Lee, Su-Seung;Yi, Jong-Heop
    • Macromolecular Research
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    • v.17 no.3
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    • pp.192-196
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    • 2009
  • Recently, the multi-screening of target materials has been made possible by the development of the surface plasmon resonance (SPR) imaging method. To adapt this method to biochemical analysis, the multi-patterning technology of protein microarrays is required. Among the different methods of fabricating protein microarrays, the microfluidic platform was selected due to its various advantages over other techniques. Microfluidic devices were designed and fabricated with polydimethylsiloxane (PDMS) by the replica molding method. These devices were designed to operate using only capillary force, without the need for additional flow control equipment. With these devices, multiple protein-patterned sensor surfaces were made, to support the two-dimensional detection of various protein-protein interactions with SPR. The fabrication technique of protein microarrays can be applied not only to SPR imaging, but also to other biochemical analyses.

Observations of surface roughness of Co-Cr alloys according to grinding time of dental barrel finishing (치과용 바렐연마기의 연마시간에 따른 Co-Cr 합금의 표면거칠기 관찰)

  • Ko, Hyeon-Jeong;Park, Yu-Jin;Choi, Sung-Min
    • Journal of Technologic Dentistry
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    • v.43 no.3
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    • pp.93-98
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    • 2021
  • Purpose: The aim of this study was to observe the surface roughness and surface topography of cobalt-chrome (Co-Cr) alloys with grinding time in dental barrel finishing. Methods: This study involved two types of Co-Cr alloys. Specimens were manufactured with the dimensions 10×10×2 mm. Each specimen was cast according to the manufacturer's instructions. The cast alloys were polished for 35 minutes at intervals of five minutes in an automatic barrel finishing. Specimens were imaged with a three-dimensional optical microscope to measure surface roughness. Results: BC specimens and GM specimens had the highest roughness (Ra) values in the ungrained control group, and the lowest Ra values were measured 20 minutes after grinding. Conclusion: The best conditions for grinding Co-Cr alloy using a dental barrel finishing were a weight ratio of polishing media, water, and compound of 150 g:200 g:5 g, and a rotation speed of 450 rpm. Grinding time to obtain appropriate surface roughness should be limited to 15 to 30 minutes.

Self-Supported NiSe/Ni Foam: An Efficient 3D Electrode for High-Performance Supercapacitors

  • Zhang, Jingtong;Zhao, Fuzhen;Du, Kun;Zhou, Yan
    • Nano
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    • v.13 no.11
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    • pp.1850136.1-1850136.12
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    • 2018
  • Three-dimensional (3D) mixed phases NiSe nanoparticles growing on the nickel foam were synthesized via a simple one-step hydrothermal method. A series of experiments were carried out to control the morphology by adjusting the amount of selenium in the synthetic reaction. Meanwhile, the as-prepared novel column-acicular structure NiSe exist three advantages including ideal electrical conductivity, high specific capacity and high cycling stability. It delivered a high capacitance of $10.8F\;cm^{-2}$ at a current density- of $5mA\;cm^{-2}$. An electrochemical capacitor device operating at 1.6 V was then constructed using NiSe/NF and activated carbon (AC) as positive and negative electrodes. Moreover, the device showed high energy density of $31W\;h\;kg^{-1}$ at a power density of $0.81kW\;kg^{-1}$, as well as good cycling stability (77% retention after 1500 cycles).

Estimation of 3D active earth pressure under nonlinear strength condition

  • Zhang, D.B.;Jiang, Y.;Yang, X.L.
    • Geomechanics and Engineering
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    • v.17 no.6
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    • pp.515-525
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    • 2019
  • The calculation of active earth pressure behind retaining wall is a typical three-dimensional (3D) problem with spatial effects. With the help of limit analysis, this paper firstly deduces the internal energy dissipation power equations and various external forces power equations of the 3D retaining wall under the nonlinear strength condition, such as to establish the work-energy balance equation. The pseudo-static method is used to consider the effect of earthquake on active earth pressure in horizontal state. The failure mode is a 3D curvilinear cone failure mechanism. For the different width of the retaining wall, the plane strain block is inserted in the symmetric plane. By optimizing all parameters, the maximum value of active earth pressure is calculated. In order to verify the validity of the new expressions obtained by the paper, the solutions are compared with previously published solutions. Agreement shows that the new expressions are effective. The results of different parameters are given in the forms of figures to analysis the influence caused by nonlinear strength parameters.

A Study on the Optimum Machining Conditions and Energy Efficiency of a Laser-Assisted Fillet Milling

  • Woo, Wan-Sik;Lee, Choon-Man
    • International Journal of Precision Engineering and Manufacturing-Green Technology
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    • v.5 no.5
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    • pp.593-604
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    • 2018
  • Laser-assisted machining (LAM) is known to be an effective and economical technique for improving the machinability of difficult-to-machine materials. In the LAM method, material is preheated using a laser heat source and then the preheated area is removed by following cutting tool. For laser-assisted turning (LAT), the configuration of the system is not complicated because laser irradiates from a fixed position. In contrast, laser-assisted milling (LAMill) system is not only complicated but also difficult to control because laser heat source must always move ahead of the cutting tool along a three dimensional (3D) tool path. LAMill is still early stage and cannot yet be used to machine finished products with 3D shapes. In this study, a laser-assisted fillet milling process was developed for machining 3D shapes. There are no prior studies combining fillet milling and LAMill. Laser-assisted fillet milling strategy was proposed, and effective depth of cut (EDOC) was obtained using thermal analysis. Experiments were designed using response surface method and cutting force prediction equations were developed using statistical analysis and regression analysis. The optimum machining conditions were also proposed, and energy efficiency of the LAMill was analyzed by comparing the specific cutting energy of conventional machining (CM) and LAMill.

Electromyography-signal-based muscle fatigue assessment for knee rehabilitation monitoring systems

  • Kim, Hyeonseok;Lee, Jongho;Kim, Jaehyo
    • Biomedical Engineering Letters
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    • v.8 no.4
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    • pp.345-353
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    • 2018
  • This study suggested a new EMG-signal-based evaluation method for knee rehabilitation that provides not only fragmentary information like muscle power but also in-depth information like muscle fatigue in the field of rehabilitation which it has not been applied to. In our experiment, nine healthy subjects performed straight leg raise exercises which are widely performed for knee rehabilitation. During the exercises, we recorded the joint angle of the leg and EMG signals from four prime movers of the leg: rectus femoris (RFM), vastus lateralis, vastus medialis, and biceps femoris (BFLH). We extracted two parameters to estimate muscle fatigue from the EMG signals, the zero-crossing rate (ZCR) and amplitude of muscle tension (AMT) that can quantitatively assess muscle fatigue from EMG signals. We found a decrease in the ZCR for the RFM and the BFLH in the muscle fatigue condition for most of the subjects. Also, we found increases in the AMT for the RFM and the BFLH. Based on the results, we quantitatively confirmed that in the state of muscle fatigue, the ZCR shows a decreasing trend whereas the AMT shows an increasing trend. Our results show that both the ZCR and AMT are useful parameters for characterizing the EMG signals in the muscle fatigue condition. In addition, our proposed methods are expected to be useful for developing a navigation system for knee rehabilitation exercises by evaluating the two parameters in two-dimensional parameter space.

Performance Analysis of S-SFR-based OFDMA Cellular Systems

  • Kim, Yi-Kang;Cho, Choong-Ho;Yoon, Seok-Ho;Kim, Seung-Yeon
    • KSII Transactions on Internet and Information Systems (TIIS)
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    • v.13 no.1
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    • pp.186-205
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    • 2019
  • Intercell interference coordination (ICIC) is considered as a promising technique to increase the spectral efficiency of OFDMA cellular systems. The soft frequency reuse (SFR) and fractional frequency reuse (FFR) are representative and efficient management techniques for ICIC. Herein, to enhance the performance of the SFR scheme, we propose a call admission (CAC) scheme. In this CAC scheme, called Spectrum handoff-SFR(S-SFR), the spectrum handoff technique is applied to the user equipment (UE) located near the cell center. We derive the traffic analysis model to describe the S-SFR. In addition, a two-dimensional (2-D) Markov chain and an outage analysis are used in our analytical model. From the traffic analysis, the significant performance measures are the outage probability, call blocking probability, system throughput and resource utilization. Based on those, the outage probability and system throughput are obtained using resource utilization as an interference pattern. The analytical results are verified with computer simulation results. Finally, we compare our proposed scheme with other ICI schemes.

An Experimental Study of Optimal Performance of Rear Wheel Steering Vehicle for Maneuverability (기동성을 위한 후륜 조향 차량의 최적 성능에 대한 연구)

  • Ann, Kookjin;Joa, Eunhyek;Park, Kwanwoo;Yoon, Youngsik;Yi, Kyongsu
    • Journal of Auto-vehicle Safety Association
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    • v.11 no.2
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    • pp.23-28
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    • 2019
  • This paper presents an optimal performance of rear wheel steering vehicle for maneuverability. The maneuverability of vehicle is evaluated in terms of yaw rate, body slip angle and driver input. The maneuverability of vehicle can be improved by rear wheel steering system. To obtain optimal performance of rear wheel steering vehicle, the optimal control history is designed. The high dimensional trajectory optimization problem is solved by formulating a quadratic program considering rear wheel steer input. To evaluate handling performance 7 degree-of-freedom vehicle model with actuation sub-models is designed. A step steer test is conducted to evaluate rear wheel steering vehicle. A response time, a TB factor, overshoot, and yaw rate gain are investigated through objective criteria, assessment webs. The handling performance of vehicle is evaluated via computer simulations. It has been shown from simulation studies that optimal controlled rear wheel steering vehicle provides improved performance compared to others.

Nanofluid flow and heat transfer from heated square cylinder in the presence of upstream rectangular cylinder under Couette-Poiseuille flow

  • Sharma, Swati;Maiti, Dilip K.;Alam, Md. Mahbub;Sharma, Bhupendra K.
    • Wind and Structures
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    • v.29 no.1
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    • pp.65-75
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    • 2019
  • A heated square cylinder (with height $A^*$) is kept parallel to the cold wall at a fixed gap height $0.5A^*$ from the wall. Another adiabatic rectangular cylinder (of same height $A^*$ and width $0.5A^*$) is placed upstream in an inline tandem arrangement. The spacing between the two cylinders is fixed at $3.0A^*$. The inlet flow is taken as Couette-Poiseuille flow based non-linear velocity profile. The conventional fluid (also known as base fluid) is chosen as water (W) whereas the nanoparticle material is selected as $Al_2O_3$. Numerical simulations are performed by using SIMPLE algorithm based Finite Volume approach with staggered grid arrangement. The dependencies of hydrodynamic and heat transfer characteristics of the cylinder on non-dimensional parameters governing the nanofluids and the fluid flow are explored here. A critical discussion is made on the mechanism of improvement/reduction (due to the presence of the upstream cylinder) of heat transfer and drag coefficient, in comparison to those of an isolated cylinder. It is observed that the heat transfer increases with the increase in the non-linearity in the incident velocity profile at the inlet. For the present range studied, particle concentration has a negligible effect on heat transfer.

Virtual reality-based mild cognitive impairment prevention training system (가상현실기반의 경도인지장애 예방 훈련 시스템)

  • Choi, Ki-won;Joo, Moon-il;Kim, Hee-cheol
    • Proceedings of the Korean Institute of Information and Commucation Sciences Conference
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    • 2016.10a
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    • pp.749-751
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    • 2016
  • Due to the advent of virtual reality, the past communication method using images and video through the expansion into three-dimensional space has been provided more realistic and seamless interaction environment. Unlike reality, virtual reality is under a full human control and due to this benefit can be used as a substitute for reality therefore medicine and healthcare area has attracted attention in the prevention and treatment of dementia utilizing virtual reality. The research provided in this paper is aimed to design a virtual reality-based mild cognitive impairment prevention training system, focusing on the Symptoms of Alzheimer's precursor, mild cognitive impairment.

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