• The Korean Journal of Physiology
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• v.30 no.1
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• pp.21-31
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• 1996

To investigate the mechanisms of increased endothelium-dependent contraction by acetylcholine in hypertensive rats, the relationship between endothelium-dependent contraction by acetylcholine and blood pressure was studied in spontaneously hypertensive rats (SHR), one-kidney, one clip Goldblatt hypertension (1K,1C-GBH) rats, and Wistar-Kyoto rats (WKY). SHR were treated orally with enalapril or nicardipine in order to prevent development of hypertension or suppress the developed hypertension. 1K,1C-GBH rats were made by renal artery stenosis with contralateral nephrectomy in 8 week-WKY. 1. Endothelium-dependent contractions by acetylcholine $(10^{-6}{\sim}10^{-5}\;M)$ in SHR were significantly greater than those in WKY. 2. Chronic treatment with enalapril or nicardipine reduced the endothelium-dependent contraction in SHR 3. The degree of reduction of endothelium-dependent contraction was greater in SHR which was prevented from developing hypertension than in SHR of which high blood pressure was suppressed. 4. In aortic rings from 1K,1C-GBH rats, endothelium-dependent contractions by acetylcholine were augmented as compared with WKY. 5. There is good relationship between the value of blood pressure and magnitude of endothelium-dependent contraction. Thus, it is suggested that increased endothelium-dependent contraction in hypertensive rats may he due to the high blood pressure and endothelium-dependent contraction may not be a cause of the initiation of hypertension in SHR.

• Journal of the Korean Data and Information Science Society
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• v.25 no.4
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• pp.745-753
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• 2014

Parrondo paradox is the counter-intuitive situation where individually losing games can combine to win or individually winning games can combine to lose. In this paper, we compare the history-dependent Parrondo games and the space-dependent Parrondo games played cooperatively by the multiple players. We show that there is a probability region where the history-dependent Parrondo game is a losing game whereas the space-dependent Parrondo game is a winning game.

• International Journal of Control, Automation, and Systems
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• v.5 no.2
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• pp.170-183
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• 2007

This paper presents a delay-dependent approach to robust filtering for linear parameter-varying (LPV) systems with discrete and distributed time-invariant delays in the states and outputs. It is assumed that the state-space matrices affinely depend on parameters that are measurable in real-time. Some new parameter-dependent delay-dependent stability conditions are established in terms of linear matrix inequalities (LMIs) such that the filtering process remains asymptotically stable and satisfies a prescribed $H_{\infty}$ performance level. Using polynomially parameter-dependent quadratic (PPDQ) functions and some Lagrange multiplier matrices, we establish the parameter-independent delay-dependent conditions with high precision under which the desired robust $H_{\infty}$ filters exist and derive the explicit expression of these filters. A numerical example is provided to demonstrate the validity of the proposed design approach.

• Structural Engineering and Mechanics
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• v.41 no.1
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• pp.139-155
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• 2012

Structural health monitoring systems are often installed on bridges to provide assessments of the need for structural maintenance and repair. Damage or deterioration may be detected by observation of changes in bridge characteristics evaluated from measured structural responses. However, construction materials such as concrete and steel cables exhibit certain time-dependent behaviour, which also results in changes in structural characteristics. If these are not accounted for properly, false alarms may arise. This paper proposes a systematic and efficient method to study the time-dependent effects on the dynamic properties of cable-stayed bridges. After establishing the finite element model of a cable-stayed bridge taking into account geometric nonlinearities and time-dependent behaviour, long-term time-dependent analysis is carried out by time integration. Then the dynamic properties of the bridge after a certain period can be obtained. The effects of time-dependent behaviour of construction materials on the dynamic properties of typical cable-stayed bridges are investigated in detail.

• Sleep Medicine and Psychophysiology
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• v.15 no.2
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• pp.77-81
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• 2008

Introduction: REM sleep which shows characteristic muscle atonia and increased resistance of upper respiratory track is known to be vulnerable to sleep apnea. Previous studies reported that REM sleep-dependent (or related) obstructive sleep apnea syndrome (REM-dependent OSA) could be one of sleep disordered breathing. The present study aimed to investigate clinical findings and polysomnographic variables of REM-dependent OSA. Methods: Fifty-six patients diagnosed with mild to moderate obstructive sleep apnea by overnight polysomnography (5$53.7{\pm}16.7$ years, 42 males). REM-dependent OSA was defined as AHI-REM/AHI-NREM ratio>2. We compared clinical and polysomnographic findings between REM-dependent OSA and No REM-dependent OSA patients. Results: Among 56 patients, 37.5% (n=21, average age of $52.3{\pm}19.7$ years, 14 males) met the REM-dependent OSA criteria. There were no significant differences in age, sex and body mass index between two groups. After controlling for age, sex, body mass index and periodic leg movements index, REM-dependent OSA patients showed significantly lower AHI, lower number of oxygen desaturation events and higher stage 2 sleep proportion compared to No REM-dependent OSA patients (p=0.010, p=0.006, p=0.031, respectively). After controlling for age, sex, body mass index and periodic legs movements index, AHI-REM was positively correlated with the number of oxygen desaturation events in REM-dependent OSA group (p=0.002). Conclusion: Current results suggested that 37.5% of patients with mild to moderate severity of obstructive sleep apnea could be classified into REM-dependent OSA. REM-dependent OSA was more common in mild severity of OSA, equally prevalent in both sexes and accompanied with sleep architecture changes, i.e. increased proportion of stage 2. In addition, apneic events during REM sleep in REM-dependent OSA were related to oxygen desaturation.

• 제어로봇시스템학회:학술대회논문집
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• 2004.08a
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• pp.433-438
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• 2004

In this paper, we at first describe the linear age-dependent population system. In addition, we introduce the nonlinear population system. Using these age-dependent population systems, we evaluate the stability of these age-dependent population systems and determine the optimal birth rates that realize a target distribution which relaxes an aging population. In this paper, we focus on Japan's population and we use the amount of demographic statistics of Japan in year 2000.

• The Transactions of The Korean Institute of Electrical Engineers
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• v.59 no.4
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• pp.788-792
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• 2010

The problem of delay-dependent and parameter-dependent robust stability condition for discrete-time uncertain singular systems with polytopic uncertainty and interval time-varying delay is considered. A new robust stability condition based on parameter-dependent Lyapunov function is derived in terms of LMI (linear matrix inequality). Moreover, the proposed robust stability condition is a general condition for both singular and non-singular systems. A numerical example is presented to demonstrate the effectiveness of the proposed method.

• Communications of the Korean Mathematical Society
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• v.13 no.1
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• pp.151-158
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• 1998

In this note we derive inequalities of linearly positive quadrant dependent random variables and obtain a strong law of large numbers for linealy positive quardant dependent random variables. Our results imply an extension of Birkel's strong law of large numbers for associated random variables to the linear positive quadrant dependence case.

• Honam Mathematical Journal
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• v.25 no.1
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• pp.117-127
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• 2003

In this note we perform an extreme point analysis on two natural definitions of negative quadrant dependence of three random variables and examine how different these two notions of dependence. We also characterize some special distributions which are both negatively lower orthant dependent and negatively upper orthant dependent.

• Journal of the Chungcheong Mathematical Society
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• v.34 no.1
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• pp.27-35
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• 2021

We study the existence of positive T-periodic solutions of ratio-dependent predator-prey systems with time periodic and spatially dependent coefficients. The fixed point theorem by H. Amann is used to obtain necessary and sufficient conditions for the existence of positive T-periodic solutions.