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A Retrospective Analysis of Treatment-Related Prognostic Factors for Local Recurrence after Primary Radiation Therapy for Patients with Primary T1N0 Glottic Cancer (T1N0 성문암의 방사선치료관련 예후 인자 분석)

  • Kim Su-Ssan;Kim Sang-Yoon;Nam Soon-Yuhl;Choi Seung-Ho;Cho Kyung-Ja;Kim Jong-Hoon;Ahn Seung-Do;Shin Seong-Soo;Song Si-Yeol;Choi Eun-Kyung;Lee Sang-Wook
    • Korean Journal of Head & Neck Oncology
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    • v.19 no.1
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    • pp.34-40
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    • 2003
  • Objective: To analyze the treatment-related parameters after the radiotherapy of T1N0 squamous cell carcinoma of the glottic larynx. Materials and Methods: Between October 1989 and August 2000, 54 patients with histologically proven T1N0 squamous cell carcinoma of the glottic larynx who received definitive radiation therapy in Department of Radiation Oncology, Asan Medical Center were analyzed. They were all males with age ranged from 31 to 80 years (median 61 years). 1997 AJCC stages were 31 T1a, 23 T1b. Patients were treated with 4-MV X-rays with a parallel-opposed two-field technique. Ten patients received 66.0-68.4Gy at 1.2Gy per fraction twice daily, 21 patients received 64.8-66.6Gy at 1.8Gy per fraction once daily, and 23 patients received 66.0Gy at 2.0Gy per fraction once daily. Follow-up period was 16-119 months (median 56 months). Results: 5-year overall survival and local control rates for patients with T1 lesions were 87.0% and 88.5%, respectively. 5-year local control with larynx preservation rate was 90.5%. Host and tumor-related prognostic factors including age, stage, anterior commissure involvement and tumor bulk proved not to be significant. Only shorter overall treatment time among treatment-related factors had correlation with imporved local control. Conclusion: Comparable high local control rate with organ preservation was achieved with primary radiation therapy and salvage surgery. Shortening of overall treatment time is related to improved local control rate. To determine the optimal fractionation scheme, randomized trial is mandatory.

An Evaluation Validity of the Silicone Replica Technique at Measurement on Fit of Fixed Dental Prostheses (고정성 보철물의 적합도 측정 시 사용하는 실리콘 복제본 기술의 정확도 평가)

  • Kim, Jae-Hong;Kim, Ki-Baek
    • Journal of dental hygiene science
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    • v.12 no.6
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    • pp.566-571
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    • 2012
  • Marginal and internal fit are very important factor for the clinical long-term success of fixed dental prostheses (FDPs). A variety of methods have been applied to the measuring marginal and internal fit of FDPs. The purpose of this study was to compare the marginal and internal fit of 2 different measuring methods silicone replica technique [SRT] and die cutting technique (DCT). SRT, the space between die and FDPs were filled with light-body silicone, then stabilized by medium-body silicone. DCT, the FDPs were cemented on definitive dies and embedded into epoxy. The silicone replicas and epoxies were sectioned mesio-distal and measured 4 locations (margin, rounded chamfer, axial, occlusal) and using a digital microscope at a magnification $\times$160. For the SRT the mean${\pm}$SDs fit (${\mu}m$) recorded were: margin $88.7{\pm}22.2$, rounded chamfer $90.6{\pm}25.0$, axial wall $61.5{\pm}21.8$, occlusal $134.9{\pm}30.8$. For the DCT the mean${\pm}$SDs fit (${\mu}m$) recorded were: margin $85.3{\pm}18.0$, rounded chamfer $85.4{\pm}24.7$, axial wall $62.0{\pm}21.3$, occlusal $131.7{\pm}30.5$. The mean${\pm}$SDs size (${\mu}m$) of SRT margin was $88.7{\pm}22.2$ and of DCT margin was $85.3{\pm}18.0$. There were no statistically significant difference (p<0.05) of the four parts between SRT and DCT. It is considered an appropriate case to use SRT at fit of FDPs.

Study on G. Deleuze's "Francis Bacon: The Logic of Sensation" - Focus Primarily on Concept of 'Figure' - (들뢰즈의 『감각의 논리』에 관한 연구 - '형상'개념을 중심으로 -)

  • Jin, Gi-haeng
    • Journal of Korean Philosophical Society
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    • v.141
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    • pp.263-286
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    • 2017
  • It is well known to us that in its enlarged sense Deleuze's philosophy has confrontation with platonism that has dominated the whole western ideas, and in a narrow sense it is confrontation with representative thinking and representative arts. In other words, it's obvious what Deleuze has considered the most important in his whole of ideas is to think not in a representative way but in a non-representational way and to disentangle thinking from its representative image. To examine the way how Deleuze criticize representation, and how he overcome modern ideas is not just to make a clean breast of platonic inheritance. Because they are essential for facing up to the actual circumstances of our contemporaries who have degraded servility of totalitarian thoughts under the thinking of identity, and furthermore, it is essential for overcoming this situation and proceeding to nomadic thinking, liberating thinking. This study is not intended to be a definitive account of all his criticism of representation. Because, as is well known, Deleuze's criticism of representation contains a wide variety. And so this study were limited a relatively small number of points in Deleuze's position on representation as follows. How does Deleuze's criticism of representation has been developed in his theory of paintings? And what does it mean to us today? In this paper, I paid special regard to make sense out Deleuze's concept of 'figure' in his important writings that pertains to an analysis of his criticism of representation, Francis Bacon: The Logic of Sensation. And having traced the development process of the concept of 'figure', I want to understand the implicit meaning of the concept in constant flux of his critical thinking.

Petrography and Mineral Chemistry of Some Deep Sea Basaltic Rocks from the Western Caroline Ridge and Yap Trench-Arc System (서부 캐롤라인 해령과 얍 해구-열도계의 해저 현무암질암에 대한 암석 기재 및 광물화학)

  • Park Jun-Beom;Kwon Sung-Tack;Ahn Jung-Ho;Kang Jung-Keuk
    • The Journal of the Petrological Society of Korea
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    • v.1 no.1
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    • pp.71-84
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    • 1992
  • This paper reports the results about the petrography and mineral chemistry of 13 representative dredged basaltic rocks from the western Caroline Ridge (WCR) and Yap Trench-Arc system, and provides the chemical and tectonic informations based on the compositions of clinopyroxene phenocrysts. Compositions of olivine phenocrysts in some analyzed samples are Fo$_{86-80}$. Plagioclase phenocrysts have variable compositions ranging from An$_{90}$ to An$_{55}$. The compositions of clinopyroxene phenocrysts vary according to geological environments; titansalite in atoll and guyot of WCR, diopside-augite in trough and bank of WCR, and endiopside in Yap Trench-Arc system. Application of the discrimination schemes proposed by Leterrier et al. (1982) suggests: (1) the samples from atoll-guyot belong to within plate alkali basalt, implying that western CR could be the continuation of eastern CR formed by hot spot magmatism, (2) the samples from the Yap Trench-Arc system with no present-day magmatism clearly indicate the occurrence of orogenic tholeiites presumably related to early island arc magmatisms in this area, however, (3) the samples from the bank and trough do not provide definitive informations, which might indicate the complexity of their origins.

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Full mouth rehabilitation in patient with deep bite, inter-dental arch discrepancy and loss of vertical dimension: a case report (과개교합과 치열궁부조화 및 수직고경 감소를 가진 환자의 전악수복증례)

  • Song, Han-Sol;Lee, Ye-Jin;Ko, Kyung-Ho;Huh, Yoon-Hyuk;Cho, Lee-La;Park, Chan-Jin
    • Journal of Dental Rehabilitation and Applied Science
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    • v.37 no.3
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    • pp.157-170
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    • 2021
  • Loss of posterior bite support might cause unstable occlusal relationship and when the mandible slides forward in the centric or habitual occlusion, excessive load is applied to the anterior region followed by causing the occlusal plane to collapse or leading to a decrease in occlusal vertical dimension. In addition, disorder of temporomandibular joint function may occur. The inter-dental arch discrepancy causes a mismatch in the vertical and horizontal overlap of the anterior and posterior regions. The deep bite in the anterior region and the scissor bite in the posterior region cause unstable occlusal contact and insufficient occlusal contact area. This report was to rehabilitate a patient with above-mentioned complex problems. Physiologic adaptation to increased vertical dimension and new occlusal plane were evaluated using provisional prostheses, and definitive prostheses was fabricated using cross-mounting technique. Stable occlusion, harmonious teeth overlap and adequate occlusal plane were established, so functionally and aesthetically satisfactory results are obtained.

Prosthetic rehabilitation of an oligodontia patient with atrophic maxilla (위축된 상악골을 가진 부분무치증 환자의 보철수복)

  • Chi, Seung-Seok;Kim, Ye-Jin;Kang, Hyeon-Goo;Ko, Kyung-Ho;Huh, Yoon-Hyuk;Park, Chan-Jin;Cho, Lee-Ra
    • The Journal of Korean Academy of Prosthodontics
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    • v.59 no.2
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    • pp.238-247
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    • 2021
  • Congenital tooth agenesis is the most common developmental dental anomaly, of which oligodontia is defined as the absence of six or more permanent teeth, except the third molars. Tooth agenesis causes malocclusion, alveolar atrophy, aesthetic and psychosocial problems. This clinical report describes a multidisciplinary treatment for a patient diagnosed as oligodontia, who exhibited absence of 14 permanent teeth, atrophy of maxillary alveolar bone, and mandibular protrusion. Restoration space was secured and tooth axis was improved by the extraction of deciduous teeth and orthodontic treatment. However, edge-to-edge bite of posterior teeth and arch dimension discrepancy due to atrophic maxilla was remained. To restore the aesthetics and functionality, implant retained prosthesis was planned. Considering minimal bone grafts, location and number of dental implants and prostheses design were determined. Through the gradual adjustment of provisional restoration, the appropriate centric and eccentric occlusion was reflected into a definitive prosthesis. Currently, stable functional results were attained, however, regular follow up and maintenance care over lifetimes should be performed.

A study on the controversy of the modernity of the Tsukiji Little Theater -With a focus on Kabuki, Shinpa, and Shingeki- (축지소극장의 근대성 문제에 대한 연구 -가부키(歌舞伎), 신파(新派), 신극(新劇)의 연관성-)

  • Kim, Hyeoncheol
    • Journal of Korean Theatre Studies Association
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    • no.48
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    • pp.421-446
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    • 2012
  • The purpose of this paper is to shed light onto the historical significance and limitations of the Tsukiji Little Theater's modern performances. The Tsukiji Little Theater holds a position of great importance to the history of both Japanese and Korean modern theater. Some, however, are under the completely opposite impression. There are also mixed opinions about whether the Tsukiji Little Theater is a "model example" of the modern theatrical movement or a "bad example". Based on this controversy, we look into the definitive characteristics of the Tsukiji Little Theater based mostly on "the controversy over translated foreign plays", "the controversy of foreign plays versus original plays", "the value of kabuki" and "Shinpa as a rival". This paper looked into the differences in controversy over translated foreign plays in the Tsukiji Little Theater and the controversy in existing translated foreign plays. It mostly looks at the "casuistry of foreign plays" and the "cultural engineering theory of foreign plays"to get a grasp on the controversy surrounding existing translated foreign plays. Meanwhile, the "internally critical meaning" towards the original plays of renowned writers was strong in the controversy of foreign plays in the Tsukiji Little Theater. Kaoru Osanai defined the 1920s as a dark period, and persisted that because of the activity of the Shingeki movement, foreign plays were needed instead of low-level original plays. This study examines the characteristics of original plays and foreign plays publicly performed at the Tsukiji Little Theater to analyze the "controversy of translated foreign plays versus original plays". The Tsukiji Little Theater mostly put on shows with a strong sense of resistance or that defied the old times. This caused there to be a lot of emphasis put on the rebellious mindset towards old conventions and ideologies for most of the plays, both foreign and original, and the problem arises that little mind was paid to the integrity or beauty of the works. In looking at the "value of kabuki", this paper looked into Kaoru Osanai, who was deeply involved in kabuki actors. He evaluated traditional Japanese arts highly not because of the literary value of their scripts, but because he recognized the value of how they were performed. In order to create a new spectacle, music, dance and mime was taken in from countries around the world, and kabuki was regarded highly as a means of expression on stage. Finally, we also examine the recognized reasons for treating Shinpa as a rival. There is a relationship between these reasons and a complex about the audiences they drew. The Shinpa performances always had many spectators and were successful, but those at the Tsukiji Little Theater were so unpopular with the public that it was hard for them to financially run their theater group. The empty seats in their theater constantly made the modern intellectuals in the Shingeki movement feel inferior.

The use of implant surveyed fixed prosthesis for removable partial denture with a few unilateral remaining teeth: A case report (편측 소수 잔존치 증례에서 CAD software를 활용한 planning 및 임플란트 서베이드 고정성 보철물을 이용한 국소의치 수복: 증례보고)

  • Park, Jeongkeun;Kim, Jong-Eun;Park, Ji-Man;Kim, Jeehwan;Shim, June-Sung
    • The Journal of Korean Academy of Prosthodontics
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    • v.57 no.3
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    • pp.254-262
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    • 2019
  • As implant can be covered by National Health Insurance Service (NHIS), it was increased the interest in the removable partial denture (RPD) with the surveyed fixed prosthesis supported by implant fixture. To achieve predictable result, it needs the prudent implant planning by basic principles of RPD and patient's residual ridge. This 67 years old age male had a few unilateral remaining teeth, and hoped the treatment covered by NHIS. As using CAD software, the position of implant is planned with regarding to occlusal table of provisional denture, basic principles of RPD, and resorbed residual ridge. The definitive prostheses can ensure the stability and retention of removable prosthesis. When planning implant fixed prostheses, the digital technique was utilized to consider basic principle of RPD and resorbed residual ridge. As a result, it provided satisfactory prostheses.

Cognitive Impairments and Its Related Factors Among the Centenarians in Korea (우리나라 100세 이상 고령자의 인지기능장애 수준과 관련요인)

  • Park, Seok-Yong;Bae, Jin-Sung;Cho, Young-Chae
    • Journal of the Korea Academia-Industrial cooperation Society
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    • v.19 no.12
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    • pp.584-591
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    • 2018
  • This study was conducted to determine the levels of cognitive impairment (MMSE-K) among centenarians, and to reveal their association with related variables. The study subjects were 268 centenarians who received medical check-ups from the National Health Insurance Corporation during the period of 2016-2017. The levels of cognitive impairment were significantly reduced among females as well as those living with spouses and children, lower monthly income, lower BMI and individuals who engaged in smoking and alcohol consumption without regular exercise relative to their respective counterparts. The risk of definitive cognitive impairment in study subjects was significantly higher among women (ORs=9.85, 95% CI=2.88-33.59) than men and was lower in obese group (ORs=0.25, 95% CI=0.07-0.86) than in low weight groups, as well as in non-smoking (ORs=0.30, 95% CI=0.10-0.83) than smoking groups. The factors influencing the cognitive impairment of study subjects were sex, living status, monthly income, BMI and smoking status. Taken together, these results suggest that the levels of cognitive impairments among centenarians differed significantly in response to socio-demographic characteristics and health related variables. Especially, the levels of cognitive impairments decreased among those with poor health related variables such as smoking, alcohol consumption and regular exercise.

Clinical Outcomes of Differentiated Thyroid Cancer Patients with Local Recurrence or Distant Metastasis Detected in Old Age

  • Han, Ji Min;Bae, Ji Cheol;Kim, Hye In;Kwon, Sam;Jeon, Min Ji;Kim, Won Gu;Kim, Tae Yong;Shong, Young Kee;Kim, Won Bae
    • Endocrinology and Metabolism
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    • v.33 no.4
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    • pp.459-465
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    • 2018
  • Background: Differentiated thyroid carcinoma (DTC) shows a very good prognosis, but older patients have a higher recurrence rate and those show poor prognosis than younger patients. The aim of this study was to determine the clinical outcomes of thyroid cancer patients who experienced recurrence in old age according to the treatment strategy used. Methods: This retrospective observational cohort study was conducted at Asan Medical Center, Seoul, Korea. Among DTC patients with no evidence of disease after initial treatment, we enrolled 86 patients who experienced recurrence at an age >65 years from 1994 to 2012. Sixty-nine patients had local recurrence and 17 patients showed distant metastasis. Results: The mean age of patients at recurrence was 72 years. Patients were followed up for a median of 4.1 years after recurrence. Sixty-three of the 69 patients with local recurrence received additional treatment, while the other six received conservative care. The cancer-specific mortality rate was 15.5% in the local recurrence group. Airway problems were the main cause of death in patients who did not receive further treatment for local recurrence. Among the 17 patients with distant metastasis, 10 underwent specific treatment for metastasis and seven received only supportive management. Seven of those 17 patients died, and the cancer-specific mortality rate was 35% in the distant metastasis group. Conclusion: The overall cancer-specific mortality rate was 20% in DTC patients in whom recurrence was first detected at an age >65 years. Mortality due to uncontrolled local disease occurred frequently in patients who did not receive definitive management for recurrence.