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Development of 1.0 Tesla Compact MRI System (1.0 Tesla 자기 공명 진단 장치의 개발)

  • Lee, H.K.;Oh, C.H.;Ahn, C.B.;Chang, Y.H.;Shin, D.W.;Lee, K.N.;Jang, K.H.
    • Proceedings of the KOSOMBE Conference
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    • v.1996 no.11
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    • pp.129-134
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    • 1996
  • 1차 년도 G-7 개발 과제로 수행된 자기 공명 진단 장치 (Magnetic Resonance Imaging System)의 개발 내용을 간략히 소개하였다. 성공적인 IT Compact 자기 공명 진단 장치의 완성을 위해 일차적으로 (1)RF (고주파), Gradient(경사 자계), Spectrometer 등의 Hard-ware 관련 MRI 핵심부분, (2) RF, Gradient, Spectrometer, Magnet 등의 각 Sub-system을 연결, 조합, 조정하여 하나의 체계적인 시스템으로 통합하고 운영하는 과정(System Integration), (3)사용자와 시스템을 연결하는 User Interface, Data Base Management, Real time 운영 SW 등과 (4)임상에 적용하여 구체적인 성능과 효용성을 확인하는 기술 등에 대하여 집중 연구하였다. 개발 방법은 (1)지난 16년간 국내에 축적 된 연구 개발 인력들을 최대한 활용하고 (2)연구 개발을 국제화 시켜 필요한 경우 부분별로 개발 인력을 해외에서 보완하고 (3)소수 정예 전문 인력 주의와 요소 기술 또는 중요 부품을 경쟁성 검토 후 필요 시 Out-sourcing 활용으로 최저의 비용으로 개발 기간을 최소화 하는 데 두었다. 개발된 1.0Tesla자기 공명 영상 장치는 미국 물리 학회에서 규격화한 Phantom및 임상 적용을 통하여 서울대 의대 연구 팀과 지속적으로 성능을 평가해 왔다. 개발된 시스템의 해상도는 $256{\times}256$ head 영상에서 1mm 이 하의 해상도를 가짐을 resolution phantom 을 통하여 확인할 수 있었고, $512{\times}512$ 영상에서 는 약 0.5 mm 의 물체를 분리 해냄으로써 외제 시스템들 보다 우수하게 평가 되었다. 차폐 경사코일의 Eddy current영향은2%이내로 촬영 시 영향은 거의 무시할 수 있었다. 또한, 개발된 영상 기법들, 즉 Multislice/Multi Echo, Oblique angle imaging, 64 Echo train을 갖는 고속 촬영 기술들이 자기 공명 장치에 장착되어 임상 적용에 문제가 없도록 하였다. 또한 20mT/m/Amp의 강력한 능동 차폐 경사 자계 코일(Active Shield Gradient Coil)을 기본 사양으로 하고, 수신단을 최대 6개로 확장토록 하여 2차년도의 초고속 촬영 기법(EPI) 및 Phased Array 코일 촬영이 가능토록 하였다. 1차 년도 개발 과제 수행 결과와 향후 개발 과제를 바탕으로 최종 목표인 국제 경쟁력이 있는 자기 공명 진단 장치 즉 기능과 영상의 질은 선진국 제품과 동일하거나 우수하되, 저가격을 구현한 상용화 제품이 완성되어, 첨단 의료기기로서 산업 구조 고도화에 기여하고 수입대체 뿐만 아니 라 수출을 통한 국익 창출과 국가의 기술을 통한 위상 제고에 기여되길 기대한다.

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U.S. Policy and Current Practices for Blending Low-Level Radioactive Waste for Disposal (저준위 방사성폐기물의 혼합 관련 미국의 정책과 실제 적용)

  • Kessel, David S.;Kim, Chang-Lak
    • Journal of Nuclear Fuel Cycle and Waste Technology(JNFCWT)
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    • v.14 no.3
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    • pp.235-243
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    • 2016
  • In the near future, many countries, including the Republic of Korea, will face a significant increase in low level radioactive waste (LLW) from nuclear power plant decommissioning. The purpose of this paper is to look at blending as a method for enhancing disposal options for low-level radioactive waste from the decommissioning of nuclear reactors. The 2007 U.S. Nuclear Regulatory Commission strategic assessment of the status of the U.S. LLW program identified the need to move to a risk-informed and performance-based regulatory approach for managing LLW. The strategic assessment identified blending waste of varying radionuclide concentrations as a potential means of enhancing options for LLW disposal. The NRC's position is that concentration averaging or blending can be performed in a way that does not diminish the overall safety of LLW disposal. The revised regulatory requirements for blending LLW are presented in the revised NRC Branch Technical Position for Concentration Averaging and Encapsulation (CA BTP 2015). The changes to the CA BTP that are the most significant for NPP operation, maintenance and decommissioning are reviewed in this paper and a potential application is identified for decommissioning waste in Korea. By far the largest volume of LLW from NPPs will come from decommissioning rather than operation. The large volumes in decommissioning present an opportunity for significant gains in disposal efficiency from blending and concentration averaging. The application of concentration averaging waste from a reactor bio-shield is also presented.

A study on development of RGB color variable optical ID module considering smart factory environment (스마트 팩토리 환경을 고려한 RGB 컬러 가변형 광 ID 모듈개발 연구)

  • Lee, Min-Ho;Timur, Khudaybergenov;Lee, Beom-Hee;Cho, Ju-Phil;Cha, Jae-Sang
    • The Journal of Korea Institute of Information, Electronics, and Communication Technology
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    • v.11 no.5
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    • pp.623-629
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    • 2018
  • Smart Factory is a concept of automatic production system of machines by the fusion of ICT and manufacturing. As a base technology for realizing such a smart factory, there is an increasing interest in a low-power environmentally friendly LED lighting system, and researches on so-called optical ID related application technologies such as communication using a LED and position recognition are actively underway. In this paper, We have proposed a system that can reliably identify logistics location and additional information without being affected by electromagnetic interference such as high voltage, high current, and generator in the plant. Through the basic experiment, we confirmed the applicability of the color ID recognition rate from 98.8% to 93.8% according to the eight color variations in the short distance.

A Study on the selection and noise test of elelctronic sensor for Vacuum Circuit Breaker (진공차단기용 전자식 센서의 선정 및 노이즈 시험에 관한 연구)

  • Lee, Ki Seon;Park, Jung Cheul;Chu, Soon Nam
    • Journal of the Korea Institute of Information and Communication Engineering
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    • v.18 no.10
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    • pp.2503-2508
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    • 2014
  • This study is about the selection and noise test of electronic sensor which is preceded by electric Operating Cell(EOC) development using electronic sensor technology to solve the structural weakness of Mechanism Operated Cell(MOC) in VCB, and has a final target in product development minimizing contact malfunction of the chattering or rebounce states caused by existing MOC. In this test results, when opening and closing VCB, rising velocity of surge voltage in opening time was measured 4.2 times faster than closing time and noise decibel value was measured respectively 120dB and 110dB. When supplying 60kV power frequency overvoltage, we found that sensor output graph in VCB opening and closing times operated stably without distortion. When supplying 150kV $1.2{\times}50{\mu}s$ impulse frequency voltage, we found that voltage graph of output contact in sensor opening and closing sides maintained a normal condition without distortion, and when supplying 2500A current, we found that tested result of electric field noise operated stably without distortion.

Nano-scale Patterning on Diamond substrates using an FIB (FIB를 이용한 다이아몬드 기판 위의 나노급 미세 패턴의 형상 가공)

  • Song, Oh-Sung;Kim, Jong-Ryul
    • Journal of the Korea Academia-Industrial cooperation Society
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    • v.7 no.6
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    • pp.1047-1055
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    • 2006
  • We patterned nano-width lines on a super hard bulk diamond substrate by varying the ion beam current and ion beam sources with a dual beam field ion beam (FIB). In addition, we successfully fabricated two-dimensional nano patterns and three-dimensional nano plate modules. We prepared nano lines on a diamond and a silicon substrate at the beam condition of 30 kV, 10 pA $\sim$ 5 nA with $Ga^+$ ion and $H_2O$ assisted ion sources. We measured each of the line-width, line-depth, etched line profiles, etch rate, and aspect ratio, and then compared them. We confirmed that nano patterning was possible on both a bulk diamond and a silicon substrate. The etch rate of $H_2O$ source can be enhanced about two times than that of Ga source. The width of patterns on a diamond was smaller than that on a silicon substrate at the same ion beam power The sub-100 nm patterns on a diamond were made under the charge neutralization mode to prevent charge accumulation. We successfully made a two-dimensional, 240 nm-width text of the 300-lettered Lord's Prayer on a gem diamond with 30 kV-30 pA FIB. The patterned text image was readable with a scanning electron microscope. Moreover, three dimensional nano-thick plate module fabrication was made successfully with an FIB and a platinum deposition, and electron energy loss spectrum (EELS) analysis was easily performed with the prepared nano plate module.

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Energy Harvesting Characteristics of Interdigitated (IDT) Electrode Pattern Embedded Piezoelectric Energy Harvester (IDT 전극 패턴 임베디드 압전 에너지 하베스터의 특성)

  • Lee, Min-seon;Kim, Chang-Il;Yun, Ji-sun;Park, Woon Ik;Hong, Youn-Woo;Paik, Jong Hoo;Cho, Jeong Ho;Park, Yong-Ho;Jang, Yong-Ho;Choi, Beom-Jin;Jeong, Young-Hun
    • Journal of the Korean Institute of Electrical and Electronic Material Engineers
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    • v.29 no.9
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    • pp.581-588
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    • 2016
  • Piezoelectric thick films of a soft $Pb(Zr,Ti)O_3$ (PZT) based commercial material were produced by a conventional tape casting method. Thereafter, the interdigitated (IDT) Ag-Pd electrode pattern was printed on the $25{\mu}m$ thick piezoelectric film at room temperature. Co-firing of the 10-layer laminated piezoelectric thick films was conducted at $1,100^{\circ}C$ and $1,150^{\circ}C$ for 1 h, respectively. Piezoelectric cantilever energy harvesters were successfully fabricated using the IDT electrode pattern embedded piezoelectric laminates for 3-3 operation mode. Their energy harvesting characteristics were investigated with an excitation of 120 Hz and 1 g under various resistive loads (ranging from $10k{\Omega}$ to $200k{\Omega}$). A parabolic increase of voltage and a linear decrease of current were shown with an increase of resistive load for all the energy harvesters. In particular, a high output power of 3.64 mW at $100k{\Omega}$ was obtained from the energy harvester (sintered at $1,150^{\circ}C$).

Development and Application of Water Quality Level Model (WQLM) for the Small Streams of Rural Watersheds with Discriminant Analysis (판별분석을 통한 농촌유역 소하천의 수질등급모형(WQLM) 개발 및 적용)

  • Kim, Jin-Ho;Choi, Chul-Mann;Ryu, Jong-Soo;Jung, Goo-Bok;Shin, Joung-Du;Han, Kuk-Heon;Lee, Jung-Taek;Kwun, Soon-Kuk
    • Journal of Korean Society on Water Environment
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    • v.23 no.2
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    • pp.260-265
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    • 2007
  • This study was carried out to complement water quality standards and to establish new concept for water quality standards reflecting current state of water quality in small streams. By this purpose, discriminant analysis was performed and Water Quality Level Model (WQLM) was developed using the data such as EC, BOD, $COD_{Mn}$, SS, T-N, T-P, $NH_3-N$ in 224 agricultural streams. To give water quality level for water quality parameters, it divided into 20% respectively in the order of excellent water quality. On the basis of the lowest water quality level, water quality level of small streams is granted. As a result of it, number of stream corresponding to Level I was no, Level II was 2 streams, Level III was 22 streams, Level IV was 70 streams, and Level V was 130 streams. Average of water quality in each level was the highest in Level V. EC, SS, and T-N of 7 parameters were selected in variance concerned water quality level. By standardized canonical discriminant function coefficient, EC of three variances was the highest in 0.625 at the discriminant power. The next was T-N (0.509), SS (0.414). By discriminant function for water quality level, Level II was equal to $-2.973+19.376{\times}(EC)+0.647{\times}(T-N)+0.009{\times}(SS)$, Level III was equal to $-3.288+19.190{\times}(EC)+0.733{\times}(T-N)+0.041{\times}(SS)$, Level IV was equal to $-4.462+27.097{\times}(EC)+0.792{\times}(T-N)+0.053{\times}(SS)$, and Level V was equal to $-9.117+40.040{\times}(EC)+1.305{\times}(T-N)+0.111{\times}(SS)$. As a result of test at real agricultural watershed of Jeongan and Euidang in Gongju city, the fitness of WQLM was high to 88.78%. But, to get accomplished water quality assessment more exactly in agricultural streams, we had to concentrate and get vast data, and WQLM was modified and complemented continually.

T$a_2O_5$Dielectric Thin Films by Thermal Oxidation and PECVD (열산화법 및 PECVD 법에 의한 T$a_2O_5$ 유전 박막)

  • Mun, Hwan-Seong;Lee, Jae-Seok;Lee, Jae-Seok;Lee, Jae-Seok;Yang, Seung-Gi;Lee, Jae-hak;Park, Hyung-ho;Park, Jong-wan
    • Korean Journal of Materials Research
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    • v.2 no.5
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    • pp.353-359
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    • 1992
  • Thermal oxidation and plasma enhanced chemical vapor deposition of tantalum oxide thin films on p-type (100) Si substrates were studied to examine the dielectric nature of T$a_2O_5$ as a Al/T$a_2O_5$/p-Si capacitor. Microstructure and dielectric properties of the capacitors were investigated by XRD, AES, high frequency C-V analyzer, I-V meter and TEM. XRD analysis showed that the structure of T$a_2O_5$ films were amorphous, but the films were crystallized to hexagonal $\delta$-T$a_2O_5$ by 65$0^{\circ}C$ thermal oxidation treatment. It was found that the stoichiometry of the films was more or less close to 2 : 5. Leakage current density and relative dielectric constant of thermal oxidation T$a_2O_5$ film at 60$0^{\circ}C$ was 5.0${ imes}10^{-6}$/A/c$m^2 and 31.5, respectively. In the case of PECVD T$a_2O_5$film deposited at 0.47W/c$m^2 they were 2.5${ imes}10^{-5}$/A/$ extrm{cm}^2$ and 24.0, respectively. The morphology of the films and interfaces were investigated by TEM.

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Preparation and Bioequivalence Test of Acetaminophen Liquid Suppository (아세트아미노펜 액상좌제의 제초 및 생물학적 동등성 평가)

  • 김종국;최한곤;이사원;고종호;이미경
    • Biomolecules & Therapeutics
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    • v.6 no.2
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    • pp.213-218
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    • 1998
  • A novel in situ-gelling and mucoadhesive acetaminophen liquid suppository was developed to improve the patient compliance of conventional solid suppository. In this study, acetaminophen liquid suppository, Likipe $n_{R}$, [aminophen/Poloxamer 407/Poloxamer 188/so4ium alginate (5/15/19/0.6%)] with relation temperature at 30-36 "C and suitable gel strength and bioadhesive force, dissolution pattern similar to conventional solid type suppository, Suspe $n_{R}$, was developed. Furthermore, the bioequivalence of two acetaminophen products was evaluated in 16 normal male volunteers (age 22-27 yr, body weight 56-72 kg) following sidle rectal administration. Test product was Likipe $n_{R}$ suppository (Dong-Wha Pharm. Corp., Korea)and reference product was Suspe $n_{R}$204-212 suppository (Hanmi Pharm. Corp., Korea). Both products contain 125 mg of acetaminophen. Four Suppositories of the test and the reference product were administered to the volunteers, respectively, by randomized two period cross-over study (2$\times$2 Latin square method). The determination of acetaminophen was accomplished using HPLC. Average drug concentrations at each sampling time and pharmacokinetic parameters calculated were not significantly different between two products (p>0.05); the area under the curve to last sampling time (24 hr) (AU $Co_{-2}$4h/) (30.14$\pm$8.64 vs 27.98$\pm$ 6.53 $\mu$g .h/ml), maximum plasma concentration ( $C_{max}$) (3.29$\pm$0.87 vs 3.60$\pm$0.66 $\mu$g/ml) and time to maximum plasma concentration ( $T_{max}$) (2.91 $\pm$0.55 vs 2.69$\pm$0.60 h). The differences of mean AUCo $_{24h}$, C-a. and T-between the two products (7.18%, 9.58% and 7.53%, respectively) were less than 20%. The power (1-7) and treatment difference ($\Delta$) for AU $Co_{24h}$, $C_{max}$ and $T_{max}$ were more than 0.8 and less than 0.2, respectively at $\alpha$=0.1. The confidence limits for AU $Co_{24h}$, $C_{max}$ and $T_{max}$ (-0.81 ~13.55%, -1.56~ 17.60 and -3.81 ~18.87%, respectively) were less than $\pm$ 20% at $\alpha$=0.1. These results suggest that the bioavailability of Likipe $n_{R}$ suppository is not significantly different from that of Suspe $n_{R}$ suppsitory. Therefore, two products are bio-equivalent based on the current results.results.lts.sults.results.lts.

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Personal Values and their Relationships with Public Library Use (개인의 가치관과 공공도서관 이용간의 관계성 분석)

  • Kwon, Nahyun
    • Journal of the Korean Society for Library and Information Science
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    • v.52 no.2
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    • pp.143-164
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    • 2018
  • The purpose of this study was to investigate the relationship between public library use and the individual's personal value system. The personal value system was measured by Schwartz's (1992) Theory of Basic Human Values. The theory includes ten universal values, which can be categorized into four higher-order values: namely, self-transcendence vs. self-enhancement; and openness to change vs. conservation. The data were collected on the web from 1,000 Korean adults who were 18 years old or above using a quota sampling method with respect to the distributions of gender, age, and geographic locations of the general Korean adult population. The collected data were analyzed using multi-dimensional scaling method, t-tests, and multiple correlations. The results showed that the public library is more likely to be used by the individuals who value "openness to change" (representing self-direction and stimulation), and "self-enhancement"(representing achievement, power, hedonism/sensuous pleasure) than those who value "conservation" (representing safety, stability of society, conformity to rules, tradition) and "self-transcendence" (representing interest in other's well-being, and tolerance, welfare of humanity and community). The findings suggest that public library uses reflect the characteristics of major library services, such as reading and self-learning, which are very autonomous and individualistic in their nature. The findings are valuable in understanding the nature of the functions performed by the current Korean public libraries that are reflected in the personal values of Korean adult library users.