• Journal of The Korean Society of Integrative Medicine
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• v.7 no.2
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• pp.141-151
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• 2019

Purpose : Hypochlorous acid (HOCl), a major inorganic bactericidal compound of innate immunity, is effective against a broad range of microorganisms. In particular, HOCl is well-known as a non-antibiotic antimicrobial substance. However, effects of HOCl as an antimicrobial agent are still needed to study these functions against various specific type of microorganisms. In this study, we investigated the antimicrobial effect of hypochlorous acid (HOCl) in S. mutans and A. actinomycetemcomitans to cause dental caries and periodontal disease. Experiments were conducted to observe whether HOCl become effective replacement of disinfectant. Methods : To observe antimicrobial effect of HOCl, stabilized HOCl is prepared in the form of a physiologically balanced solution in pre-conditioned and post-conditioned HOCl solution. As a control, commercially available disinfectant MAXCLEAN was used as positive control. Moreover, S. mutans and A. actinomycetemcomitans distribution in gagrin, filtered tap water, and culture media. Cell viability were measured by viable cell count methods and disk diffusion test. Results : Our results showed that treatment of HOCl have no effect against antimicrobial effect compare to control group especially gagrin in disk diffusion test. HOCl tended to reduced viability against S. mutans in group of post-conditioned than pre-conditioned of HOCl solution however, there was no significant difference as well as no effect in A. actinomycetemcomitans. Conclusion : HOCl showed tendency to reduce viability against S. mutans in group of post-conditioned of HOCl solution and no effect of antimicrobial effect. Although HOCl is well known as effective against a broad range of microorganisms, HOCl seems to have diversity following type of species to be used as antimicrobial drug following our results. Therefore, it is necessary to be rigidly controlled and regulated in using HOCl solution clinically.

• Journal of dental hygiene science
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• v.21 no.2
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• pp.119-126
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• 2021

Background: Dental caries is mainly composed of various cellular components and is deposited around the tooth surface and gums, causing a number of periodontal diseases. Streptococcus mutans is commonly found in the human oral cavity and is a significant contributor to tooth decay. The use of antibacterial ingredients in oral hygiene products has demonstrated usefulness in the management of dental caries. This study investigated the anticaries effect of the ethanol extract of Terminalia chebula (EETC) against S. mutans and their cytotoxicity to gingival epithelial cells. Methods: The EETC was prepared from T. chebula fruit using ethanol extraction. Disk diffusion, minimum inhibitory concentration (MIC), minimum bactericidal concentration (MBC), and colony forming unit (CFU) were analyzed to investigate the antimicrobial activity of the EETC. Glucan formation was measured using the filtrate of the bacterial culture medium and sucrose. Gene expression was analyzed using reverse transcription-polymerase chain reaction (RT-PCR). Cytotoxicity was analyzed via the 3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyl tetrazolium bromide assay. Results: The antibacterial activity of the EETC was explored using disc diffusion and CFU measurements. The MIC and MBC of the EETC were 10 and 20 ㎍/ml, respectively. EETC treatment decreased insoluble glucan formation by S. mutans enzymes and also resulted in reduced glycosyltransferase B (gtf B), gtf C, gtf D, and fructosyltransferase (ftf), expressions on RT-PCR. In addition, at effective antibacterial concentrations, EETC treatment was not cytotoxic to gingival epithelial cells. Conclusion: These results demonstrate that the EETC is an effective anticaries ingredient with low cytotoxicity to gingival epithelial cells. The EETC may be useful in antibacterial oral hygiene products for the management of dental caries.

• Asia pacific journal of information systems
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• v.30 no.2
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• pp.397-419
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• 2020

Business analytics is a management tool for achieving significant business performance improvements. Many organizations fail to or only partially achieve their business objectives and goals from business analytics. Business analytics adoption is a multi-stage complex activity consisting of evaluation, adoption, and assimilation stages. Several research papers have been published in the field of business analytics, but the research on multi-stage BA adoption is fewer in number. This study contributes to the scant literature on the multi-stage adoption model by identifying the critical themes for evaluation, adoption, and assimilation stages of business analytics. This study uses the thematic content analysis of peer-reviewed published academic papers as a research technique to explore the key themes of business analytics adoption. This study links the critical themes with the popular theoretical foundations: Resource-Based View (RBV), Dynamic Capabilities, Diffusion of Innovations, and Technology-Organizational-Environmental (TOE) framework. The study identifies twelve major factors categorized into three key themes: organizational characteristics, innovation characteristics, and environmental characteristics. The main organizational factors are top management support, organization data environment, centralized analytics structure, perceived cost, employee skills, and data-based decision making culture. The major innovation characteristics are perceived benefits, complexity, and compatibility, and information technology assets. The environmental factors influencing BA adoption stages are competition and industry pressure. A conceptual framework for the multi-stage BA adoption model is proposed in this study. The findings of this study can assist the practicing managers in developing a stage-wise operational strategy for business analytics adoption. Future research can also attempt to validate the conceptual model proposed in this study.

• Food Science and Preservation
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• v.20 no.1
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• pp.111-120
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• 2013

Sprassis crispa was cultivated using soybean curd whey, and its antimicrobial activities were examined against those of eight microorganisms that were foodborne pathogens or food-poisoning bacteria. The culture broth of soybean curd whey was superior in mycelium content (17.76 g/L) to that of the defined culture broth, and the ${\beta}$-glucan content was about 10.64 percent (w/w). The antimicrobial activities of the culture broth were confirmed against those of B. cereus, St. aureus, L. monocytogenes and S. typhimurium using the paper disk method. The antimicrobial activity was also maintained after the heat treatment and alcalase treatment. The filtrate with less than 3 kDa M.W. also showed the antimicrobial activity against four strains: B. cereus, St. aureus, L. monocytogenes and S. typhimurium. The minimum inhibitory concentration (MIC) was about 1.26 mg/mL in the B. cereus and 12.6 mg/mL in the St. aureus and L. monocytogenes. The S. typhimurium showed a MIC of 62.8 mg/mL. Thus, the culture of Sparassis crispa using soybean curd whey provides a thermally stable antimicrobial agent that can be used as a natural preservative in the biofood industry.

• The Journal of the Convergence on Culture Technology
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• v.9 no.3
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• pp.769-777
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• 2023

Globalization has brought about rapid economic, technological, and cultural changes. In order for countries around the world to communicate, recognize and understand globalization, creativity or planning ability can be used to code. In this paper, we would like to present and prove a data analysis that can solve world problems. In the global market, the value of goods or services increases with connectivity. This connection is becoming one of the factors that increase the value of culture. Changes taking this into account promoted cultural spread and innovative growth, and increased productivity and competitiveness in each region of the world. This paper compares the income of the middle class in the United States on the impact of globalization and anti-globalization on cultural spread and innovative growth. Globalization has created an environment in which various elements of K-culture can interact and spread. Through the Internet, social media, and international travel, globalization has had a positive impact on Korea's innovative growth. In areas such as economic activity, technological innovation, and creative industries, globalization has facilitated new tech and approaches, Through this, it changed the existing economic model and contributed to exports K-culture with a new middle class model. However, globalization in the cultural industry can result in the loss of regional characteristics & individuality, which can lead to the middle class cultural unification and alienation(chasm). As a result of the empirical analysis of K-exports for the middle income in the United States, cultural diffusion and innovation must be developed even in anti-globalization. With these industrial changes the soft power value of the Korean Wave proves that it can create value for use for the middle class of major exporting countries.

• The Journal of the Convergence on Culture Technology
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• v.7 no.4
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• pp.613-621
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• 2021

This study conducted a network analysis to determine how COVID-19 vaccine-related issue spread on Twitter during the introduction stage of the COVID-19. Issue diffusion tendency is analyzed according to the time period: phase 1 (initiation of vaccine introduction: March 7 - April 3, 2021), phase 2 (stagnant period of vaccination: April 4 - April 22, 2021), and phase 3 (increase of vaccination: April 23 - May 5, 2021). NodeXL was used for data collection and analysis. Daily Twitter network data were collected by entering search terms highly related to the COVID-19 vaccine. This study found that side effects-related opinions were repeatedly formed throughout the analysis period. As the vaccination rate increased and death cases were reported on media, death-related issues also emerged on Twitter. On the other hand, vaccine safety did not receive much attention on Twitter. The results of this study highlight the role of social media as a channel of issue diffusion when a national disaster strikes. We emphasize the need for the government to monitor public opinions on social media and reflect them in crisis communication strategies.

• The Journal of the Convergence on Culture Technology
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• v.10 no.5
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• pp.803-808
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• 2024

As a service that creates graphic work images with AI, DALL-E2, Midjourney, Stable Diffusion, BING image generator, and Playground AI are widely used. It is that graphic also enables learner-led customized education. With this, it is worth studying detailed design customized learning materials and methods for designing efficient design in future 2D graphic work, and it is necessary to explore the areas of application. The current situation is that it is necessary to develop a design education system that can indicate the lack of AI technology through text security and questions. In this study, a successful proposal for a process that is produced through a process of creating AI design work through proxy work can be presented as a conclusion. Design, advertisement, and visual content companies are already using and adapting, and the trend is to reflect the AI graphic utilization ability and results in the portfolio along with interviews when hiring new employees. In line with this, detailed consideration and research on visual and design production methods for AI convergence between instructors and learners are currently needed. In this paper, proposals and methods for image quality production were considered in the main body and conclusions, and conclusive directions were proposed for five alternatives and methods for future applications.

• The Research Journal of the Costume Culture
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• v.14 no.5
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• pp.864-875
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• 2006

The characteristics of the demographics in Korea as it gets older are the increase of Elderly Women and continuous progress in urbanization. In this study, body shapes are classified as standard, obese, and tiny according to the previous studies based on the body shape characteristics and the body measurement of the Elderly Women. Based on the classification, we developed prototype of the panty for the Elderly Women to provide basic materials for the quality enhancement of the clothing of the increasing Elderly Women. The followings are the result of the study. 1. To categorize the body shapes of the Elderly Women focusing on the lower half, we grouped the target subjects using the nested approach by the average standard deviation and the factor analysis minimal diffusion method. Accordingly, type 1 and 2 had 36 members respectively and type 3 had 43 members. In this study, two Elderly Women subjects with standard body shape falling under the type 1 were selected as the subjects. 2. In the second trial evaluation for the prototype panty for the Elderly Women 32 items for appearance test and 3 items for functional test were evaluated. The scores in leg, sideline and hip were shown high and the balance between the parts was maintained very well. In the functional test, the panty used to be too tight for the leg curve but in the second trial it was improved, too. In each item, the second trial test showed better score than the first trial test. Conclusively, the most optimal panty prototype for the Elderly Women was proposed according to the trial test result.

• The Research Journal of the Costume Culture
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• v.15 no.5
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• pp.737-748
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• 2007

Korea is now entering into aging society next to Japan in Asia, which is considered as unusual in the semi-developed countries. More than 50 year-old consumer market is anticipated to grow to 28.7% of the total in 2010 from 20.4% in 2000. In particular, the silver market is estimated to be formed in full range in 2010 when the generation born in 50s and 60s after the Korean War start to retire. In this study, body shapes are classified as standard, obese, and tiny according to the previous studies based on the body shape characteristics and the body measurement of the Elderly Women. Based on the classification, we developed pattern of the panty for the obese Elderly Women to provide basic materials for the quality enhancement of the clothing of the increasing Elderly Women. The followings are the result of the study 1. To categorize the body shapes of the Elderly Women focusing on the lower half, we grouped the target subjects using the nested approach by the average standard deviation and the factor analysis minimal diffusion method. Accordingly, type 1 and 2 had 36 members respectively and type 3 had 43 members. In this study, two Elderly Women subjects with standard body shape falling under the type 1 were selected as the subjects. 2. In the second trial evaluation for the panty pattern for the Elderly Women 32 items for appearance test and 3 items for functional test were evaluated. The scores in leg, sideline and hip were shown high and the balance between the parts was maintained very well. In the functional test, the panty used to be too tight for the leg curve but in the second trial it was improved, too. In each item, the second trial test showed better score than the first trial test. Conclusively, the most optimal panty prototype for the Elderly Women was proposed according to the trial test result.

• Journal of Microbiology and Biotechnology
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• v.27 no.8
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• pp.1441-1448
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• 2017

Antibacterial compounds are widely used in the treatment of human and animal diseases. The overuse of antibiotics has led to a rapid rise in the prevalence of drug-resistant bacteria, making the development of new antibacterial compounds essential. This study focused on developing a fast and easy method for identifying marine bacteria that produce antibiotic compounds. Eight randomly selected marine target bacterial species (Agrococcus terreus, Bacillus algicola, Mesoflavibacter zeaxanthinifaciens, Pseudoalteromonas flavipulchra, P. peptidolytica, P. piscicida, P. rubra, and Zunongwangia atlantica) were tested for production of antibacterial compounds against four strains of test bacteria (B. cereus, B. subtilis, Halomonas smyrnensis, and Vibrio alginolyticus). Colony picking was used as the primary screening method. Clear zones were observed around colonies of P. flavipulchra, P. peptidolytica, P. piscicida, and P. rubra tested against B. cereus, B. subtilis, and H. smyrnensis. The efficiency of colony scraping and broth culture methods for antimicrobial compound extraction was also compared using a disk diffusion assay. P. peptidolytica, P. piscicida, and P. rubra showed antagonistic activity against H. smyrnensis, B. cereus, and B. subtilis, respectively, only in the colony scraping method. Our results show that colony picking and colony scraping are effective, quick, and easy methods of screening for antibacterial compound-producing bacteria.