• Title/Summary/Keyword: Critical state

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Heart-Model-Based Automated Method for Left Ventricular Measurements in Cardiac MR: Comparison with Manual and Semi-automated Methods (자동화 방식 모델 기반 좌심방 파라미터 측정법: 수동 및 반자동 방식과의 비교)

  • Chae, Seung Hoon;Lee, Whal;Park, Eun-Ah;Chung, Jin Wook
    • Investigative Magnetic Resonance Imaging
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    • v.17 no.3
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    • pp.200-206
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    • 2013
  • Purpose : To assess the effect of applying an automated heart model based measurements of left ventricle (LV) and compare with manual and semi-automated measurements at Cardiovascular MR Imaging. Materials and Methods: Sixty-two patients who underwent cardiac 1.5T MR imaging were included. Steady state free precession cine images of 20 phases per cardiac cycle were obtained in short axis views and both 2-chamber and 4-chamber views. Epicardial and endocardial contours were drawn in manual, automated, and semi-automated ways. Based on these acquired contour sets, the end-diastolic (ED) and end-systolic (ES) volumes, ejection fraction (EF), systolic volume (SV) and LV mass were calculated and compared. Results: In EDV and ESV, the differences among three measurement methods were not statistically significant (P = .399 and .145, respectively). However, in EF, SV, and LV mass, the differences were statistically significant (P=.001, <001, <001, respectively) and the measured value from automated method tend to be consistently higher than the values from other two methods. Conclusion: An automatic heart model-based method grossly overestimate EF, SV and LV mass compared with manual or semi-automated methods. Even though the method saves a considerable amount of efforts, further manual adjustment should be considered in critical clinical cases.

Optimization for Concurrent Spare Part with Simulation and Multiple Regression (시뮬레이션과 다중 회귀모형을 이용한 동시조달수리부속 최적화)

  • Kim, Kyung-Rok;Yong, Hwa-Young;Kwon, Ki-Sang
    • Journal of the Korea Society for Simulation
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    • v.21 no.3
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    • pp.79-88
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    • 2012
  • Recently, the study in efficient operation, maintenance, and equipment-design have been growing rapidly in military industry to meet the required missions. Through out these studies, the importance of Concurrent Spare Parts(CSP) are emphasized. The CSP, which is critical to the operation and maintenance to enhance the availability, is offered together when a equipment is delivered. Despite its significance, th responsibility for determining the range and depth of CSP are done from administrative decision rather than engineering analysis. The purpose of the paper is to optimize the number of CSP per item using simulation and multiple regression. First, the result, as the change of operational availability, was gained from changing the number of change in simulation model. Second, mathematical regression was computed from the input and output data, and the number of CSP was optimized by multiple regression and linear programming; the constraint condition is the cost for optimization. The advantage of this study is to respond with the transition of constraint condition quickly. The cost per item is consistently altered in the development state of equipment. The speed of analysis, that simulation method is continuously performed whenever constraint condition is repeatedly altered, would be down. Therefore, this study is suitable for real development environment. In the future, the study based on the above concept improves the accuracy of optimization by the technical progress of multiple regression.

Evaluation of Open-source Software for Participatory Digital Archives: Understanding System Requirements for No Gun Ri Digital Archives (참여형 아카이브 구축을 위한 오픈소스 소프트웨어 평가 - 노근리디지털아카이브 구축을 위한 예비분석 -)

  • Park, Taeyeon;Sinn, Donghee
    • Journal of Korean Society of Archives and Records Management
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    • v.16 no.1
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    • pp.121-150
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    • 2016
  • This paper reports the evaluation of six open-source software systems for participatory digital archives. This is an effort to create a digital platform for the social memory of No Gun Ri, which was first recognized in 1999 as a civilian massacre. The process of how it was reported and investigated is critical to understanding this brutal incident. In addition, the course of its cultural recovery has witnessed the reconstruction of the No Gun Ri memory. Thus, it is important to embrace the social memory around the massacre in these archives. In consideration of a virtual space for memory, this study takes the form of participatory archives to provide a mechanism in which anyone can share their memories. As a way to find a digital archives system for No Gun Ri, this study analyzed open-source software based on identified functions and requirements for participatory digital archives. Knowing the details of digital systems, this study discussed how contents for social memory can be stored and used in a digital system.

Microstructure and dielectric properties in the La2O3-doped BaTiO3 system (La2O3 첨가에 따른 BaTiO3의 미세구조 및 유전특성)

  • Choi, Woo-Jin;Moon, Kyoung-Seok
    • Journal of the Korean Crystal Growth and Crystal Technology
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    • v.30 no.3
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    • pp.103-109
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    • 2020
  • The effect of La2O3 addition on the crystalline phase, microstructure, and dielectric properties of BaTiO3 has been studied as a function of the amounts of La2O3. 0.3 mol% TiO2-excess BaTiO3 powder was synthesized by solid-state reaction, and then the powder compacts with various amounts of La2O3 were sintered at 1250℃ for 2 hours. Room temperature XRD showed changes in the lattice parameters and a decrease of tetragonality (c/a) as the amounts of La2O3 increased. It can be explained that the phase transition from tetragonal to cubic phase occurred because La3+ replaced Ba2+ site, which increased the instability of the tetragonal phase. As La2O3 was added over 0.1 mol%, the critical driving force for growth (Δgc) increased over maximum driving force (Δgmax). As the result, the grain size decreased with La2O3 addition. Dielectric constant decreased as the amounts of La2O3 increased, which was analyzed with crystal structure and microstructure.

A Critical Assessment on the Foreign Direct Investment-led Regional Development Strategy: A Case Study of Wales, UK (외국인직접투자 유치를 통한 지역발전전략의 성과와 한계: 영국 웨일스의 사례를 중심으로)

  • Lee, Dong-Heon;Sonn, Jung-Won
    • Journal of the Economic Geographical Society of Korea
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    • v.12 no.4
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    • pp.438-453
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    • 2009
  • Attracting advanced foreign enterprises into the less-developed regions has gained increasing importance as a regional development strategy in Korea. This study critically examines the foreign-direct investment-led regional development strategy of Wales, United Kingdom. Despite a high FDI inflow in manufacturing, the Welsh regional economy has suffered from specialization in low-skilled assembly with limited R&D activities, insufficient linkage with local domestic suppliers, and violent fluctuation in local employment in response to changes within the global business environment. This tendency shows that the foreign-invested companies have neither locally embedded themselves enough nor created the external agglomeration economies in the region. At the same time, the Welsh local government's excessive dependence on financial incentives packages to induce multinationals, rather than effort to create regional innovative capacity, has resulted in a sizable fiscal loss, an abused local planning process, and subordination of the local government's major administrative decision-making on foreign investors. The Welsh FDI case suggests that an effective FDI attraction policy should include inter-regional cooperation and coordination in the inward investment attraction procedure, a comprehensive land use planning process, and state-level concrete governance on FDI.

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Dual regulatory effects of PI(4,5)P2 on TREK-2 K+ channel through antagonizing interaction between the alkaline residues (K330 and R355-357) in the cytosolic C-terminal helix

  • Kim, Sung Eun;Kim, Myoung-Hwan;Woo, Joohan;Kim, Sung Joon
    • The Korean Journal of Physiology and Pharmacology
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    • v.24 no.6
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    • pp.555-561
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    • 2020
  • TWIK-related two-pore domain K+ channel-2 (TREK-2) has voltage-independent activity and shows additional activation by acidic intracellular pH (pHi) via neutralizing the E332 in the cytoplasmic C terminal (Ct). We reported opposite regulations of TREK-2 by phosphatidylinositol 4,5-bisphosphate (PIP2) via the alkaline K330 and triple Arg residues (R355-357); inhibition and activation, respectively. The G334 between them appeared critical because its mutation (G334A) endowed hTREK-2 with tonic activity, similar to the mutation of the inhibitory K330 (K330A). To further elucidate the role of putative bent conformation at G334, we compared the dual mutation forms, K330A/G334A and G334A/R355-7A, showing higher and lower basal activity, respectively. The results suggested that the tonic activity of G334A owes to a dominant influence from R355-7. Since there are additional triple Arg residues (R377-9) distal to R355-7, we also examined the triple mutant (G334A/R355-7A/R377-9A) that showed tonic inhibition same with G334A/R355-7A. Despite the state of tonic inhibition, the activation by acidic pHi was preserved in both G334A/R355-7A and G334A/R355-7A/R377-9A, similar to the R355-7A. Also, the inhibitory effect of ATP could be commonly demonstrated under the activation by acidic pHi in R355-7A, G334A/R355-7A, and G334A/R355-7A/R377-9A. These results suggest that the putative bent conformation at G334 is important to set the tug-of-war between K330 and R355-7 in the PIP2-dependent regulation of TREK-2.

An Analytical Review on the Inelastic Region of Column Strength Curve Associated with Residual Stress of Steel Member under Axial Force (강 압축 부재의 잔류응력에 따른 기둥강도곡선의 비탄성영역에 대한 해석적 고찰)

  • See, Sang-Kwang
    • Journal of the Korea institute for structural maintenance and inspection
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    • v.22 no.2
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    • pp.161-168
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    • 2018
  • This study is the analytical review on the inelastic region of CRC column strength curve. The inelastic region of CRC column strength curve is based on the Bleich theory and the maximum residual stress of $0.5{\sigma}_y$. This is somewhat conservative by considering the fact that the maximum residual stress of $0.3{\sigma}_y$ is well known. This study proposes column strength curve for nonlinear behavior of hot rolled structural steel members under axial force and tangent modulus Et, with the maximum residual stress of $0.3{\sigma}_y$ and compares them with those of CRC. The stress of the inelastic column under axial compression exceeds proportional limits and reaches yielding point before applied load render the column bent. The column strength curve that depends on gradually yielding state of section needs to be reviewed. In this study, it is derived that the critical load formular according to material yielding with the maximum residual stress of $0.5{\sigma}_y$ and compared with CRC column design curve.

A Preliminary Study of Roller Types for Chip Seals Construction (Chip Seals 시공을 위한 롤러 종류에 따른 기초적인 연구)

  • Lee, Jae-Jun;Kim, R. Young-Soo
    • International Journal of Highway Engineering
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    • v.12 no.3
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    • pp.79-85
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    • 2010
  • This paper presents a preliminary study of roller types for chip seals based on aggregate retention performance. Chip seal test sections composed of single seals of granite 78M aggregate and CRS-2 emulsion were constructed using three different roller types: the pneumatic tire roller, steel wheel roller, and combination roller. In order to investigate the performance of these rollers effectively, it is critical to test chip seal samples obtained directly from field construction. Therefore, test sections were constructed on New Sandy Hill Church Road near Bailey, North Carolina. Chip seal samples obtained from these sections were used for laboratory testing. The aggregate retention performance was evaluated using the flip-over test (FOT), Vialit test, and the third-scale Model Mobile Loading Simulator (MMLS3). Based on the test results and visual observation, both the pneumatic roller and the combination roller used together are recommended to improve chip seal performance with the sequence of the pneumatic roller rolling first followed by the combination roller.

The Response Prediction of Flexible Pavements Considering Nonlinear Pavement Foundation Behavior (비선형 포장 하부 거동을 고려한 연성 포장의 해석)

  • Kim, Min-Kwan
    • International Journal of Highway Engineering
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    • v.11 no.1
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    • pp.165-175
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    • 2009
  • With the current move towards adopting mechanistic-empirical concepts in the design of pavement structures, state-of-the-art mechanistic analysis methodologies are needed to determine accurate pavement responses, such as stress, strain, and deformation. Previous laboratory studies of pavement foundation geomaterials, i.e., unbound granular materials used in base/subbase layers and fine-grained soils of a prepared subgrade, have shown that the resilient responses followed by nonlinear, stress-dependent behavior under repeated wheel loading. This nonlinear behavior is commonly characterized by stress-dependent resilient modulus material models that need to be incorporated into finite element (FE) based mechanistic pavement analysis methods to predict more realistically predict pavement responses for a mechanistic pavement analysis. Developed user material subroutine using aforementioned resilient model with nonlinear solution technique and convergence scheme with proven performance were successfully employed in general-purpose FE program, ABAQUS. This numerical analysis was investigated in predicted critical responses and domain selection with specific mesh generation was implemented to evaluate better prediction of pavement responses. Results obtained from both axisymmetric and three-dimensional (3D) nonlinear FE analyses were compared and remarkable findings were described for nonlinear FE analysis. The UMAT subroutine performance was also validated with the instrumented full scale pavement test section study results from the Federal Aviation Administration's National Airport Pavement Test Facility (FAA's NAPTF).

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Determination of Dynamic Modulus of cold In-place Recycling Mixtures with Foamed Asphalt (폼드아스팔트를 이용한 현장 상온 재생 아스팔트 혼합물의 동탄성계수 결정)

  • Kim, Yong-Joo Thomas;Lee, Ho-Sin David
    • International Journal of Highway Engineering
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    • v.11 no.1
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    • pp.1-12
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    • 2009
  • A new mix design procedure for cold in-place recycling using foamed asphalt (CIR-foam) has been developed for Iowa Department of Transportation. Some strengths and weaknesses of the new mix design parameters were considered and modified to improve the laboratory test procedure. Based on the critical mixture parameters identified, a new mix design procedure was developed and validated to establish the properties of the CIR-foam mixtures. As part of the validation effort to evaluate a new CIR-foam mix design procedure, dynamic moduli of CIR-foam mixtures made of seven different reclaimed asphalt pavement (RAP) materials collected throughout the state of Iowa were measured and their master curves were constructed. The main objectives of this study are to provide: 1) standardized testing procedure for measuring the dynamic modulus of CIR-foam mixtures using new simple performance testing (SPT) equipment; 2) analysis procedure for constructing the master curves for a wide range of RAP materials; and 3) impacts of RAP material characteristics on the dynamic modulus. Dynamic moduli were measured at three different temperatures and six different loading frequencies and they were consistent among different RAP sources. Master curves were then constructed for the CIR-foam mixtures using seven different RAP materials. Based upon the observation of the constructed master curves, dynamic moduli of CIR-foam mixtures were less sensitive to the loading frequencies than HMA mixtures. It can be concluded that at the low temperature, the dynamic modulus is affected by the amount of fines in the RAP materials whereas, at the high temperature, the dynamic modulus is influenced by the residual binder characteristics.

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