• 대한수학회보
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• 제52권4호
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• pp.1241-1252
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• 2015

In this paper, we study the dynamical bifurcation of the modified Swift-Hohenberg equation on a periodic interval as the system control parameter crosses through a critical number. This critical number depends on the period. We show that there happens the pitchfork bifurcation under the spatially even periodic condition. We also prove that in the general periodic condition the equation bifurcates to an attractor which is homeomorphic to a circle and consists of steady states solutions.

• Journal of Preventive Medicine and Public Health
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• 제43권2호
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• pp.138-150
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• 2010

Objectives: There are at least three conceptual models for the effects of the childhood social environment on adult health: the critical period model, the social mobility model, and the cumulative risk model. However, few studies have investigated all three different models within the same setting. This study aims to examine the impact of childhood and adulthood socioeconomic positions and intergenerational social mobility over the life course on the health in adulthood based both on the critical period model and the social mobility model. Methods: This study was conducted on 9583 adults aged between 25 and 64 years old and they were the respondents to the Korea Welfare Panel Study (2006). A multivariate logistic regression analysis was carried out, using the critical period model and the social mobility model out of the life course approaches, to look into the impact of childhood and adulthood socioeconomic positions and intergenerational social mobility on the health status in adulthood. Results: Household income and occupation out of the adulthood socioeconomic position indicators had an independent influence on the adulthood health status. The childhood socioeconomic position indicators, except for the place of childhood residence, affected the adulthood health status even after adjustment for the adulthood socioeconomic position. The effect of intergenerational social mobility was also statistically significant even after adjusting for the adulthood socioeconomic position, but it became insignificant when the childhood socioeconomic position was additionally adjusted for. Conclusions: Adulthood health is indeed affected by both the childhood and adulthood socioeconomic positions as well as intergenerational social mobility. This result shows that a life course approach needs to be adopted when dealing with health issues.

• Journal of the Korean Association of Oral and Maxillofacial Surgeons
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• 제28권4호
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• pp.274-279
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• 2002

The purpose of this study is to evaluate the critical maintenance period of absorbable membrane for guided bone regeneration. Fortynine Sprague-Dawley rats weighing about 300g were divided into seven groups. An 8 mm circular full-thickness defect in calvarial bone was made and then cellular acetate porous filter (Millipore $filter^{(R)}$.) was placed on the calvarial bone defect. The filter was removed at 2, 3, 4, 5, 6, 8 and 11 weeks after placement. Rats were sacrificed at 12 weeks the placement of cellular acetate porous filter. The specimens were stained with Hematoxylin-Eosin and observed under light microscope. The amount of regenerated bone was measured from both margin of calvarial bone defect (unit : mm). The results were as follows. Bone regeneration of each experimental group was increased gradually and the bond defect was almost completely filled with new bone in 5-, 6-, 8-, and 11-week experimental group. Histologic findings showed mild inflammatory response and granulation tissue formation without apparent adverse effects on the healing process. In 11-week experimental group, the bone defect was completely filled with new bone containing abundant osteoid which was oriented to the dural side and contribute to bony thickening. We suggest that non-absorbable membrane and bioabsorbable membrane presumably should remain intact for longer than 5 weeks to be effective.

• 중환자간호학회지
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• 제17권2호
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• pp.25-41
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• 2024

Purpose : This study aimed to investigate changes in critical nursing activities from 2009 to 2020 and explore the relationship between nurse staffing and such activities in intensive care units. Methods : A total of 446,445 adult patients admitted to intensive care units in tertiary and general hospitals from 2009 to 2020 were identified using the National Health Insurance claims database. The Critical Nursing Activities Index was calculated based on the following critical nursing activities: ventilator, extracorporeal membrane oxygenation (ECMO), and continuous renal replacement therapy (CRRT). Trend analysis was performed to analyze changes in critical nursing activities over 12 years and to assess linear trends across different staffing levels. Results : The annual utilization days for ventilators, ECMO, and CRRT, as well as the Critical Nursing Activities Index significantly increased over the study period (p-for-trend<.001) in tertiary and general hospitals, except for ventilator use in general hospitals. Ventilator, ECMO, and CRRT utilization exhibited a significant upward trend with higher nurse staffing levels (Bonferroni adjusted p-for-trend<.001). The Critical Nursing Activities Index was significantly higher in hospitals with higher staffing levels compared to those with lower staffing levels (Bonferroni adjusted p <.05). Conclusion : The findings underscore the need for improved nurse staffing levels in intensive care units. Government policies should ensure that staffing levels align with critical nursing activities among critically ill patients to uphold the quality of care.

• 한국건축시공학회지
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• 제18권6호
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• pp.595-602
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• 2018

건설공사의 공정 계획에 많이 사용되는 네트워크 방식의 공정표는 CPM방식과 PERT 방식으로 분류할 수 있다. 네트워크 공정표에서는 주공정선의 산정은 전진 계산과 후진 계산을 통하여 가장 합계기간이 크게 산출되는 경로를 선택하는 방식에 의하는 것이 일반적이다. CPM 기법에서는 각 액티비티의 소요기간이 고정된 값으로 제시되므로 이를 기반으로 하여 주공정선의 산정이 용이하다. 그러나 PERT 네트워크에서는 소요기간이 확률적으로 주어지므로 단순히 특정 경로 상 액티비티 기간의 합계만으로 주공정은 정하는 것은 불합리하며, 확률에 기반하여 산정된 예상기간에 의해 최가능 주공정으로 제시되어야만 PERT의 목적에 부합할 것이다. 이는 목표 기간에 따라 주공정선이 변화할 수 있으며, 경우에 따라서는 예상 기간이 더 작은 경로가 최가능 주공정이 될 수 있음을 의미한다. 이러한 개념에 의거하여 본 연구에서는 PERT 네트워크 공정표에서 경로별로 예상기간의 비교를 통해 확률적 의미를 가진 최가능 주공정을 도출하는 기법을 제안하는 것을 목적으로 진행한다. 체계적인 대안 경로 도출을 위해 작업 구획과 작업 공정이 교차하여 반복적으로 진행하는 방식의 네트워크 반복 작업 공정표를 대상으로 하여 대안 경로 도출 방식을 제시하였으며, 도출된 경로를 대상으로 예상 기간과 표준 편차를 산출하여 예상기간이 목표 기간을 초과할 확률을 기반으로 하여 최가능 주공정을 산출하는 기법을 제안하였다. 사례 연구를 통해 최가능 주공정은 고정된 경로가 아니며 목표 기간과 표준편차에 따라 변화할 수 있음을 예시한다. 본 연구에서 제시된 기법은 건설 공사와 같이 목표 공사기간이 변화하는 상황에서 유용하게 활용될 수 있을 것이며 기간 예측의 리스크를 명확화하는데 도움을 줄 수 있을 것으로 기대된다.

• 한국콘텐츠학회논문지
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• 제16권11호
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• pp.83-90
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• 2016

본 논문에서는 저전력 통신 기술인 IEEE 802.15.4 MAC (Media Access Control) 프로토콜에서 지원하는 Collision Free Period(CFP)에서의 전송 성능 분석을 수행한다. 분석을 위해 CFP의 서비스 타겟인 주기적 트래픽을 고려하고 Quality of Service 요구사항에 따라 MAC 계층에 전달되는 패킷전달 형태를 batch와 non-batch로 구분하여 throughput, delay, energy 측면에서 성능을 분석한다. 도출된 분석 결과를 토대로 Pedometer, ECG, EMG와 같이 주기적인 트래픽을 생성하는 헬스케어 애플리케이션에 대해 Collision Avoidance Period(CAP)에서의 전송과 성능 비교를 수행한다. 성능 평가를 통해 헬스케어와 같이 주기적이며 time-critical 트래픽을 생성하는 애플리케이션은 CFP 전송이 에너지 효율적이며 대역폭 요구 사항이 큰 애플리케이션에서는 CAP 대비 최대 46%의 에너지가 절감됨을 확인하였다.

• 한국발생생물학회지:발생과생식
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• 제4권1호
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• pp.95-100
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• 2000

환경에 방출되어 있는 많은 내분비교란물질들은 사람과 동물의 내분비계에 교란을 일으킬 수 있는 잠재력을 가진다. 뇌의 성분화는 생식소 호르몬 영향하에 비가역적으로 진행되며 흰쥐의 경우 이 시기는 임신말기에서 생후 7∼10일 가량이다. 최근에 본 연구진은 횐쥐의 뇌 성 분화의 결정적인 시기에 발현되는 KAP3유전자를 클로닝하였다 (Choi ＆ Lee, 1999). KAP3의 기능은 신경세포를 포함한 세포에서 aronal tansport를 조절하는 것으로 알려져 있다. 본 연구에서는 흰쥐 뇌 발생의 결정적인 시기에 내분비 교란물질인 Dichlorodiphenyl trichloroethane (DDT)가 KAP3유전자 발현과 성분화에 미치는 영향을 검토하였다. DDT에 노출된 임신 17일된 흰쥐 태아 암컷과 수컷의 뇌에서 KAP3 mRNA의 발현이 증가하였다. 그러나 출생후 DDT에 노출된 흰쥐 암컷과 수컷의 뇌에서는 KAP3 mRNA의 발현은 감소하였다. 또한 태어난 직후 DDT에 노출된 경우 체중이 현저히 감소하였으며 수정율도 DDT에 노출되지 않은 흰쥐에 비하여 크게 낮았다. 이러한 결과는 내분비 교란물질인 DDT가 뇌의 성 분화와 관련된 유전자인 KAP3의 전사에 영향을 미치며, 내분비 교란물질에 노출된 태아의 뇌 분화에서 독성을 보이는 것을 의미한다. 그리고 KAP3유전자는 동물의 신경세포의 발생에 미치는 내분비 교란 물질의 독성을 분자생물학적으로 연구하기 위한 유전자 지표로도 사용 가능하다고 생각된다.

• 한국의료질향상학회지
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• 제27권2호
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• pp.18-29
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• 2021

Purpose: Patients with hematologic malignancy (HM) typically have a high mortality rate when their condition deteriorates. The chronic progressive course of the disease makes it difficult to assess the effect of intervention on acute events. We investigated the effectiveness of a rapid response team (RRT) on in-hospital mortality in patients with HM. Methods: We retrospectively analyzed the data of patients with HM who admitted to the medical intensive care unit between 2006 and 2015. Clinical outcomes before and after RRT implementation were evaluated. Results: A total of 228 patients in the pre-RRT period and 781 patients in the post-RRT period were included. The overall in-hospital mortality was 55.4%. Patients in the post-RRT period had improved survival; however, they required more vasopressor therapy, continuous renal replacement therapy, and extracorporeal membrane oxygenation. Multivariate analysis revealed that in-hospital mortality was associated with RRT activation (hazard ratio [HR], 0.634; 95% confidence interval [CI], 0.498-0.807; p < .001), neurological disease (HR, 2.007; 95% CI, 1.439-2.800; p < .001), sequential organ failure assessment score (HR, 1.085; 95% CI, 1.057-1.112; p < .001), need for continuous renal replacement therapy (HR, 1.608; 95% CI, 1.206-1.895; p< .001), mechanical ventilation (HR, 1.512; 95% CI, 1.206-1.895; p< .001), vasopressor (HR, 1.598; 95% CI, 1.105-2.311; p = .013), and extracorporeal membrane oxygenation (HR, 1.728; 95% CI, 1.105-2.311; p = .030). Conclusion: RRT activation may be associated with improved survival in patients with HM.

• 중환자간호학회지
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• 제11권2호
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• pp.75-85
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• 2018

Purpose : The purpose of this study was to examine the possible direction of critical care nursing research in the future by analyzing the trends of recent Korean studies. Method : Using a database search, we selected 263 articles on critical care nursing that were published in Korean journals between 2008 and 2017. Then, we conducted an integrative review of the contents of the selected articles and analyzed the English abstracts using the relevant packages and functions of the R program. Results : The number of studies concerning critical care nursing has increased over the 10-year period, and the specific topic of each study has diversified according to the time at which it was conducted. In terms of quality, the majority of the research was published in high-level academic journals. The key words regularly studied over the past decade were: knowledge, delirium, education, restraint, stress, and infection. Studies related to vancomycin-resistant enterococci infection, compliance, and standards have decreased, while studies related to death, communication, and safety have increased. Conclusion : Randomized controlled trials and protocol research for evidence-based critical care need to be conducted, as does research on family involvement. The key word analysis of unstructured text used in this study is a relatively new method; it is suggested that this method be applied to various critical care nursing research and develop it methodologically.

• Architectural research
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• 제19권1호
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• pp.21-26
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• 2017

This research examines the historic preservation of Korean modern architecture by applying Kenneth Frampton(1930-)'s concept of critical regionalism. It explores the representative Korean modern architect Gil-ryong Park (1898-1943) and two of his buildings: the Hwashin Department Store (1935) and the No-soo Park house (1937-1938). The former was in the hot spot on the preservation. There were plans to preserve this building but that it ended up being demolished in 1987. The latter building, however, has been preserved and is currently being used as a museum. These two Korean modern buildings are explored through the frame of Kenneth Frampton's critical regionalism, in particular focusing on three important concepts: "dialectical expression," "place-form," and "sustainability." In this sense, this research will provide pioneering research in understanding the preservation of Korean modern architecture through a representative Western modern theory. In the early $20^{th}$ century, Korean modern architecture, which was built during the Japanese colonial period (1910-1945), could be interpreted as critical regionalism because it represented a dialog between the West and the East, in particular between Western modernism, Japanese modernity, and Korean tradition in the East Asian context. Understanding Korean modernism in this context of a cross-cultural perspective enables scholars to define both the origins and uniqueness of Korean modern architecture.