• Proceedings of the Korea Information Processing Society Conference
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• 2017.04a
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• pp.826-828
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• 2017

그래프는 객체와 객체 간의 관계를 표현하는 데에 있어 효과적인 데이터 표현 방법이다. 그래프 데이터는 웹 그래프, 사회 관계망 서비스, 신약 개발, 생명정보학 등의 다양한 분야에서 활용되고 있으며, 그래프 마이닝 응용에서 활용되기 위한 효율적인 처리 기술을 필요로 한다. 최근까지 그래프 데이터의 처리 및 분석을 위한 많은 시스템들이 개발되었다. 본 논문에서는 최신 분산 그래프 처리 시스템 중에서 대표적인 그래프 분석 질의인 페이지랭크(pagerank)와 너비 우선 탐색(breadth first search)를 수행하고 시스템의 성능을 평가한다.

• Journal of Korea Entertainment Industry Association
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• v.14 no.3
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• pp.83-91
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• 2020

The purpose of this study is to develop creativity-based creative convergence subjects for nursing students. For the purpose of this study, the procedures are conducted that the needs analysis, setting educational goals, segmentation of educational goals, selection of educational contents and organization by F. Bobbitt's curriculum development model and the creative convergence subject was developed through the verification process of the validity of experts. Through a theoretical review, the contents of education in creative convergence subjects consisted of converging with other areas, focusing on creativity. It was presented as a liberal arts subject with two credits, and as an educational method, an online class utilizing blended learning and offline classes centered on activities by teams were presented. In addition, the curriculum was divided into understanding, application, synthesis, and deepening so that students could understand the concept of creative convergence thinking and apply it through thinking techniques and strategies, and finally improve their creative convergence thinking abilities through team projects.

• Translational and Clinical Pharmacology
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• v.25 no.2
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• pp.67-73
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• 2017

Glimepiride, a third generation sulfonylurea, is an antihyperglycemic agent widely used to treat type 2 diabetes mellitus. In this study, an untargeted urinary metabolomic analysis was performed to identify endogenous metabolites affected by glimepiride administration. Urine samples of twelve healthy male volunteers were collected before and after administration of 2 mg glimepiride. These samples were analyzed by liquid chromatography-tandem mass spectrometry (LC-MS/MS), and then subjected to multivariate data analysis including principal component analysis and orthogonal partial least squares discriminant analysis. Through this metabolomic profiling, we identified several endogenous metabolites such as adenosine 3', 5'-cyclic monophosphate (cAMP), quercetin, tyramine, and urocanic acid, which exhibit significant metabolomic changes between pre- and posturine samples. Among these, cAMP, which is known to be related to insulin secretion, was the most significantly altered metabolite following glimepiride administration. In addition, the pathway analysis showed that purine, tyrosine, and histidine metabolism was affected by pharmacological responses to glimepiride. Together, the results suggest that the pharmacometabolomic approach, based on LC-MS/MS, is useful in understanding the alterations in biochemical pathways associated with glimepiride action.

• Journal of Korea Entertainment Industry Association
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• v.15 no.1
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• pp.153-160
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• 2021

In recent universities, the new-normal era. There is a growing interest in nurturing creative thinking learners who have converged thinking necessary for the AI era based on big data. This study intends to propose the expansion of science liberal arts education necessary to meet the education needs of these universities. To this end, first the status of convergence education in universities and the elements necessary for the learners' creative ideas were examined. Second, learners who took a convergence lecture at a university will look at the development case of in which convergence thinking, creative thinking, and gaming are implemented. Based on this, we would like to propose an expanded organization and operation of science liberal arts education as a way to enhance the creative thinking of learners and their competencies through convergence classes at universities.

• Journal of the Korea Convergence Society
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• v.11 no.9
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• pp.99-107
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• 2020

The new characteristic of Millennial High-Tech Media is breaking the existing standardized creative grammar. The destructive form of high-tech media is differently accommodated according to the consumer's tendency or characteristics. The purpose of this study is to explore guidelines for effective creative strategy creation of high-tech media. In consumer psychology, consumer innovation is a key factor in evaluating the creativeness of high-tech media. The results of finding out the effect of persuasive communication on consumer innovation and advertising creative type are as follows. Informative(image) creative type showed higher attitude toward advertisement, brand attitude, purchase intention, and prior intention to consumers with high innovation than consumers with low innovation.

• Journal of Digital Convergence
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• v.7 no.3
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• pp.137-146
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• 2009

This paper aims to propose a framework of content creating group with creativity under new convergence environments. The framework is built based on content concept hierarchy(deep/surface) relating with the creativity of group members. The diversity of group members(potential creativity) decrease and change into creative abilities in one unified view at each content concept hierarchy in time. To do this, three methods of building a creative group(interaction-base, direction-base, hybrid) are proposed. Cooperating processes and operators are designed to promote creative abilities in the content producing group. These cooperations are considering new media convergence industry's job road map(IPTV) and fundamental content attributes(semantic, narrative, discourse). In the framework, creative content is produced with the help of member's cultural openness, media richness and synchronicity, hierachical adaptability on dissimilarity. Deep level creativity of cognitive semiotics on moving image content is composed of psychological, transformational, situational creating abilities in the structure of group members. Designing analogy, metaphor, symbol operators help members to traverse deep structure of content concept hierarchy. Our framework has strong points to relate fundamental content deep structure with structure of content producing group and to induce creativity on cognitive structure of human being.

• Journal of Radiopharmaceuticals and Molecular Probes
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• v.6 no.2
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• pp.155-164
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• 2020

Polyethylene glycol (PEG) has been the most commonly used polymer for the past few decades in the field of biomedical applications due to its gold standard stealth effect. PEGylation of antibody-drug conjugates, liposomes, peptides, nanoparticles, and proteins is done to improve their pharmaceutical efficacy and pharmacokinetic properties. PEGylation of antibodies with various PEG linkers improves targeting ability by increasing the blood circulation time and thus enhances the biodistribution profiles. It also assists in minimizing the immediate capture by the reticuloendothelial system. In this review, we summarize the effect of PEG linkers in an antibody conjugation and their pharmacokinetics in the field of biomedical imaging.

• Composites Research
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• v.31 no.2
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• pp.57-62
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• 2018

Interfacial and mechanical properties of neat and two sizing agents coated glass fiber (GF)/polydicyclopentadiene (p-DCPD) composites were evaluated at room and low temperatures, $25^{\circ}C$ and $-20^{\circ}C$. Sizing agents of GFs were extracted using acetone and compared via FT-IR. Surface energy and work of adhesion between GFs and p-DCPD were calculated by dynamic contact angle measurement. Mechanical properties of different GFs were determined using single fiber tensile test and interfacial properties of single GF reinforced DCPD strip were determined using cyclic loading tensile test. Mechanical properties of GFs/p-DCPD composites at room and low temperatures were determined using tensile, compressive, and Izod impact tests. Interfacial and mechanical properties were different with sizing agents of GFs and the optimized condition of sizing agent was found.

• Composites Research
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• v.30 no.3
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• pp.175-180
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• 2017

Currently, since carbon fiber reinforced plastics (CFRPs) are lightweight and have excellent physical properties, their demand has increased dramatically. Many works have studied the CFRPs based on recycled thermoplastics. In this study, the applicability of recycled composite was evaluated using recycled polyethylene terephthalate (PET). PET was collected from waste materials used in beverage bottles and processed to produce PET films. Optimal thermoforming temperature and time were analyzed by comparing the mechanical properties with forming temperature and time difference for producing PET films. CF mat and PET film were used to determine the suitable parameters for the optimum thermoforming of CF/PET composites. The mechanical properties of each thermoforming condition were verified by bending test. The degree of impregnation of the PET film into the CF mat was evaluated by cross-sectional photographs, whereas the interfacial properties were evaluated by interlaminar shear strength (ILSS). Ultimately, it was confirmed that the thermoforming condition for forming the CF/recycled PET composites yielding the optimal mechanical and interfacial properties was at $270^{\circ}C$ for 5 minutes.

• Composites Research
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• v.30 no.3
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• pp.169-174
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• 2017

Demand of glass fiber reinforced composites (GFRC) increased with developing aircraft and defense industries using resin transfer molding (RTM) process to produce complex product. In this research, wetting, interfacial, and mechanical properties were evaluated with different Cross-linking Density by Molecular Weight of Hardener. Epoxy resin as matrices was used bisphenol-A type and amine-type hardeners with different molecular weight. Specimens were manufactured via RTM and wetting property of resin and glass fiber (GF) mat was evaluated to viscosity of epoxy and injection time of epoxy matrix. Mechanical property of GFRC was determined via flexural strength whereas interfacial properties were determined by interlaminar shear strength (ILSS) and interfacial shear strength (IFSS). The difference in mechanical property depends upon the fiber weight fraction (wt %) of GFRC by RTM as well as the different Molecular Weight of Hardener.