• Journal of Haehwa Medicine
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• v.22 no.1
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• pp.91-104
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• 2013

Objective : This study was designed to analyze the clinical studies on Tic disorder in traditional Korean medicine and traditional Chinese medicine. Methods : To figure out the Tic disorder, Korean medical studies from Oriental Medicine Advanced Searching Integrated System (OASIS) and Chinese Medical Journals from Wangfang data and China National Knowledge Infrastructure (CNKI) which published in 2008 to 2012 were analyzed. Results & Conclusions : 1. DSM-IV(7 studies), CCMD(3 studies) were frequently used in the diagnosis of tic disorder. 2. The herbs used for the treatment of tic disorder are Uncariae ramulus et Uncus(釣鉤藤), Paeoniae Radix Alba(白芍藥), Poria(白茯苓), Buthus martensi Karsch(全蝎) etc. 3. Acupuncture points frequently used were Paek'oe(GV20), Pungji(GB20), Naegwan(PC6), Sasinchong(EX-HN1), T'aech'ung(LR3), Joksamni(ST36), Hapgok(LI4) and so on. 4. The cause of Tic disorder is connected with liver, heart, spleen, kidney, gall bladder among the internal organs and Fire(火), Wind(風), Dampness(濕) of external causes.

• Mycobiology
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• v.37 no.3
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• pp.225-229
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• 2009

Single spore isolates of Plasmodiophora brassicae e4 and e9 obtained from diseased Chinese cabbage were identified as race 4 and race 9, respectively, by the Williams' differential variety set. To confirm the possibility of variation in same generation and progeny of a single spore isolate of P. brassicae, random amplified polymorphic DNA (RAPD) analysis was conducted using the URP 3, 6 and OPA 7 primers. There was no difference in band type at each part of the gall of Chinese cabbage obtained by inoculation of e4 and e9 and amplification using the URP 3 and 6 primers when the same generation was analyzed. In addition, the progeny analysis, which was expanded to the third generation and conducted using the URP 3 and OPA 7 primers, revealed no differences in the band type of the e4 isolate. Based on these results, the single spore isolate of P. brassicae was genetically stable.

• The Plant Pathology Journal
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• v.17 no.2
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• pp.94-100
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• 2001

Roots of Chinese cabbage (Brassica campestris var. chinensis) seedlings infected with Plasmodiophora brassicae were examined by light and electron microscopy to reveal histopathological changes related to pathogenesis in the susceptible host. The pathogen colonized the cortex and partly the stele as well, invading up to the xylem. Gall tissues could be differentiated from the initially infected tissues, involving less compact organization and new vascular development. The infected cells were much hypertrophied, and contained one to several plasmodia. Except cellular hypertrophy, no pathological ultrastructural modification was noted in the infected calls. Infected cytoplasm became dense with ground cytoplasm, inconspicuous central vacuole, and increased cellular organelles such as mitochondria and dictyosomes. There were two types of nuclear states of plasmodium, uninucleate and multinucleate. Both plasmodia were structurally similar, filled with lipid droplets, bounded with envelope, and containing mitochondria, endo-plasmic reticulum, and sometimes small vacuoles. Plasmodial fragmentation, which may be regarded as a way to discharge plasmodial materials into host cytoplasm, commonly occurred, forming plasmodial fragments by outgrowth of plasmodial cytoplasm and regional compartmentalization. Plasmodial fragments were degenerated sometimes followed by forming chains of spherical vesicles especially in the uninucleate plasmodial state. These ultrastructural features indicate the biotrophic nature of the pathogen associated with its pathogenesis in the susceptible host.

• Journal of Physiology & Pathology in Korean Medicine
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• v.23 no.3
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• pp.540-547
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• 2009

There needs disease-predictable signs in order to enable preventive diagnosis and therapy. Then traditional Chinese medicine applies various medical diagnostic equipments used in western medicine to diagnosing sub-healthy state. But such data are not originated from inherent oriental medicine, and not obtained easily in ordinary clinical practice. This paper is to provide synopsis of the ante-disease diagno-therapeutics partly and to show predictable data based on the facial shapes and signs, especially of gall bladder's versus bladder's body and masculine versus feminine shape. Ante-disease means not only the complete healthy state, but also the state unseen any symptoms in macrographically in the course of outbreak of disease. It contains two stages, first one is the former state of disease and second one is untransmitted state of disease. The patterns of ante-disease consist of latent disease, pre-disease, transmission type like senescent syndrome, abnormal reactive syndrome(變證), syndrome of transmission and transmutation. The classification with gall bladder and bladder type manifests the differences of shape, color and size of each organ in comparison of the universal and standard figures of the human being. On the other hand, the classification with masculine and feminine shape contrasts the innate sexual difference and the shape, characteristics originated from in itself. These two classification theories have their own pathologic types and syndrome types with each disease so that disease-predictable data can be constructed based on such a relationship. In addition, this diagnostic method by facial shapes and signs is able to be applied to whole stages from prenatal to present state of disease even if the cause and inducement are not clear. Ante-disease diagno-theraputic system by Gall Bladder's versus Bladder's Body and Masculine versus Feminine Shape is getting more important in the chronic and internal disease in comparison of the acute and traumatic disease. So this study is able to make up for the limit of diagnosis on ante-disease in the field of oriental medicine clinic.

• Research in Plant Disease
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• v.9 no.2
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• pp.57-63
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• 2003

Clubroot disease of curcifer crops caused by Plasmodiophora brassicae had been first reported in 1928 in Korea, and maintained mild occurrence until 1980s. Since 1990s the disease has become severe in alpine areas of Kyonggi and Kangwon, gradually spread to plain fields throughout the country, and remains as the great-est limiting factor for its production. Researches on the disease has begun in late 1990s after experiencing severe epidemics. Survey of occurrence and etiological studies have been carried out, particularly, on the pathogen physiology, race identification, quantification of soil pathogen population, and host spectrum of the pathogen. Ecology of gall formation and its decay, yield loss assessment associated with time of infection, and relationships between crop rotation and the disease incidence was also studied during late 1990s. In studies of its control, more than 200 crucifer cultivars were evaluated for their resistance to the disease. Lime applica-tion to field soil was also attempted to reduce the disease incidence. Resistant radish and welsh onion were recommended as rotation crops with crucifers after 3-year field experiments. However, so for, most studies on clubroot disease in Korea have been focused on chemical control. Two fungicides, fluazinam and flusulfamide, were selected and extensively studied on their application technologies and combination effects with lime application or other soil treatment. To develop environmentally-friendly control methods, solar-disinfection of soil, phosphoric acid as a nontoxic compound, and root-parasiting endophytes as biocontrol agents were examined for their effects on the disease in fields. In the future, more researches are needed to be done on development of resistant varieties effective to several races of the pathogen, establishment of economically-sound crop rotation system, and improvement of soil-disinfection technique applicable to Korean field condi-tion, and development of methodology of pretreatment of fungicides onto seeds and seedbeds.

• Journal of Naturopathy
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• v.9 no.1
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• pp.13-21
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• 2020

Purpose: The purpose of this study examined the distribution of constitution(Con) types by examining the Chinese constitution table questionnaire with 594 Seoul citizens. It investigated the preferences of five colors by the Con. It then was to explore the validity of the test and the five colors according to the Con. Methods: We used the CC table questionnaire and surveyed by using a cardinal color. Results: The Con type distributions include yangweak(31.4%), yin-weak, gall-humidity, harmony, qi-weak, qi-gloom, specific, and extravasate in order. The lack of statistical significance also indicates that the CC test is not appropriate for Seoul citizens. The order of five preferences is 31% in blue, 25.3% in yellow, 18% in white, 17.7% in red, and 8% in black. Blue was the most preferred and black the least. There were differences in the distribution of five colors, but they were not statistically significant. In five viscera diseases of the yang-weak con, the stomach was more than half(50.3%). The highest preferred color was blue (30.9%). This difference was significant(p <.01). It evaluated that this influences the preference of five colors by five diseases. Conclusions: The constitution of Seoulian in the CC survey distributed into nine categories. There was a difference in preference of five colors by the con. However, it was not significant. This indicates that the Chinese con table is not suitable for Seoulian. However, the results are to be primary data for research in this field.

• Korean Journal of Organic Agriculture
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• v.23 no.2
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• pp.323-334
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• 2015

This study was conducted to develop environment-friendly agricultural products with anti-microbial activity against Acidovorax avenae subsp. citrulli as a pathogen of bacterial fruit blotch in cucurbit. Schlechtendalia chinensis was extracted by MeOH and solvent fraction. The hexane fraction, which showed highest value of anti-microbial activity, was analyzed by GC-MS. Each mass spectra, corresponding to each peak of chromatogram, was compared to MS database of Wiley library. As a result, myristic acid, palmitic acid and 3-n-pentadecylphenol were identified as maine compounds showing antimicrobial activity against A. avenae subsp. citrulli. Bioassay using commercial myristic acid, palmitic acid and 3-n-pentadecylphenol to test for the anti-microbial activity conformed the anti-microbial activity of potential active compounds, and myristic acid and 3-n-pentadecylphenol showed strong activity. In conclusion, myristic acid and 3-n-pentadecylphenol identified from S. chinensis were anti-microbial chemicals.

• Research in Plant Disease
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• v.10 no.3
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• pp.175-182
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• 2004

Teliospores of two species of Gymnosporangium asiaticum and G.yamadae collected and identified from Juniperus chinensis, J.chinensis L.var.kaizuka. G.asiaticum was identified as the thick membraned (cell-walled) teliospores (avr 2.5 ${\mu}{\textrm}{m}$) and thin membraned teliospores (avr 1.2 ${\mu}{\textrm}{m}$), and the telia of G.asiaticum was bluntly conical shaped and occured on the leaves and branches of Chinese junipers. G.yamadae was identified as the thick membraned (cell-walled) teliospores (avr 2.5 ${\mu}{\textrm}{m}$) and thin membraned teliospores (avr 1.2 ${\mu}{\textrm}{m}$), and the telia of G. yamadae was gall or floral shaped and occured on the leaves and branches of Chinese junipers. Both of the telia of the two species of Gymnosporangium were occurred in a same tree of Juniperus chinensis L. var. kaizuka at the same time. But the dominant species is G. asiaticum. The more rainfall in the late of April (the season of forming basidiospore), the more rust diseases in Chaenomeles sinensis. C. sinensis, and Pyrus pyrifolia var. culta were infected by G. asiaticum (basidiospores) but Malus siebodii was not infected by G.asiaticum.

• Asian Pacific Journal of Cancer Prevention
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• v.15 no.7
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• pp.2979-2986
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• 2014

Background: Recently, peroxiredoxin3 (PRDX3) was identified as a novel molecular marker for the progression of hepatocellular carcinoma (HCC). However, its potential clinical application as a serum marker for the early diagnosis and prognosis of HCC has not been investigated. Methods: PRDX3, alpha-fetaprotein (AFP), and other biochemical parameters were measured in serum samples from 297 Chinese patients, including 96 with HCC, 98 with liver cirrhosis (LC), and 103 healthy controls (HCs). Correlations between serum PRDX3 expression and clinicopathological variables and the relationship between serum PRDX3 expression and prognosis were analyzed. Results: Serum PRDX3 was significantly higher in HCC patients than in the LC and HC groups. The sensitivity and specificity of serum PRDX3 for the diagnosis of HCC were 85.9% and 75.3%, respectively, at a cutoff of 153.26 ng/mL, and the area under the curve was 0.865. Moreover, serum PRDX3 expression was strongly associated with AFP level, tumor diameter, TNM stage, and portal vein invasion. Kaplan-Meier curve analysis revealed that HCC patients with high serum PRDX3 expression had a shorter median survival time than those with low PRDX3 expression. Moreover, serum PRDX3 expression was an independent risk factor for overall survival. The inverse correlation between serum PRDX3 and patient survival remained significant in patients with early-stage HCC and in those with normal serum AFP levels. Conclusions: Serum PRDX3 can be used as a noninvasive biomarker for the diagnosis and/or prognosis of HCC.

• The Korean Journal of Ecology
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• v.22 no.5
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• pp.287-294
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• 1999

During the period from April to October, 1998 the authors investigated the gall development process of Chinese gallnuts (Schelchtendalia chinensis) on sumac (Rhus javanica) at Mt. Goduk near Chonju city in Chonbuk province. The majority (56.8%) of chinese gallnuts were formed on first pinnates and 24.3% on second pinnates of sumac leaves. Galls began to form from the 1st of June and grew slowly until the 24th of June. Galls enlarged rapidly after the 1st of August, but their growth rates decreased after the 26th of August and stopped growing after the 8th of September. Alate viviparous females escaped from galls after the 24th of September. Fundatricies, the second generation in the galls, exuviated three times to become adults on the 24th of June. Fundatrix adults bore 1∼10 eggs in the body and laid 1∼16 nymphs of the second generation. Nymphs of the second generation began to appear on the 17th of June and had matured completely on the 14th∼24th of July. Adults of the second generation bore eggs in the body. Thus the developmental period of the second generation was 27∼37 days. Nymphs of the third generation appeared on the 14th of July and finally alate viviparous females were developed on the 24th of September. During the two months from the beginning of the third generation to the appearence of the final alate viviparous females, there should be at least two generations, that is, the third and fourth generations. The fourth generation seems to begin at about the 20th August because the number of inhabitants (2,859 individuals) in galls on the 26 th of August had increased more than 10 times those (263 individuals) on the 19 th of August. The tannin content of galls was 65.04∼68.23% while that of sumac leaves and stems was 11.56%, 3.49% respectively.