• Title/Summary/Keyword: Chinese company

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Induction of Cytotoxicity and Apoptosis in Human Gastric Cancer Cell SGC-7901 by Isovaltrate Acetoxyhydrin Isolated from Patrinia heterophylla Bunge Involves a Mitochondrial Pathway and G2/M Phase Cell Cycle Arrest

  • Yang, Bo;Wang, Yi-Qi;Cheng, Ru-Bin;Chen, Jia-Li;Chen, Jin;Jia, Li-Tao;Zhang, Ru-Song
    • Asian Pacific Journal of Cancer Prevention
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    • v.14 no.11
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    • pp.6481-6486
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    • 2013
  • Background: Our previous study demonstrated cytotoxicity of a crude extract from Patrinia heterophylla Bunge (PHEB). In the present study, we aimed to investigate the effects of isovaltrate acetoxyhydrin (IA) isolated from PHEB on the gastric cancer cell SGC-7901, in order to explore a potential treatment for gastric cancer. Methods: MTT assays were employed to determine the effects of IA on cell vitality and proliferation, with monitoring of cell morphology changes and examination of apoptosis with Annexin V-PI staining. Flow cytometry was used to assess cell cycle progression and mitochondrial membrane potential. The activity of caspase 3, 9 was evaluated by spectrophotometry, and the protein levels of Bax, Bcl2 and Cyclin B1 were analyzed with Western blotting of total proteins extracted from cultured cells. Results: The results demonstrated direct toxicity of IA towards SGC-7901 cells. Evidence of apoptosis included blebbing and chromatin condensation. Annexin V-PI assays revealed early apoptosis, involving rapid depolarization of mitochondrial membranes and activity of caspase 3, 9 signaling pathways. Western blotting showed that Bcl2 and Bax proteins was down- and up-regulated, respectively, and cyclin B1 was up-regulated. Cell cycle analysis further indicated that IA could induce G2/M phase arrest in SGC-7901 cells. Conclusions: In conclusion, we believe that IA induces apoptosis of SGC-7901 cells, therefore providing a potential therapeutic agent for treatment of gastric cancer.

Research on the Development of One IP(intellectual property) Animation & Game in Chinese Market

  • Pan, Yang;Choi, Chul-Young;Meng, Zilu
    • International Journal of Internet, Broadcasting and Communication
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    • v.11 no.2
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    • pp.67-75
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    • 2019
  • "No IP, No Content" has become a phenomenon in the content industry, high-quality IP has a strategic importance. It has become a Trinity in the movie-anime-game basic package, Competition is more intense. However, there is a tremendous amount of know-how hidden behind the use of IP to operate games well. We are worth exploring in detail. The research and analysis of digital IP market, the advantages and disadvantages will be the focus of our pragmatic research. As an emerging market in the digital industry, China has great research value. This paper analyzes the status quo of the current Chinese market by comparing the mature US and Japanese markets. For example, the research of American Disney Company analyzes the mature market structure of Japan. compared with the excellent case of the Chinese market legend of qin. By studying the current situation of China's digital market, analyzing the interest trends of the customer base, discovering existing problems and improving the accuracy of the prediction and judgment of the Chinese digital market in the future.According to the survey, the IP heat is mainly concentrated in six categories of games, animation, TV, variety, movies, and novels. At present, the most popular IP of manufacturers have three major categories. This article will conduct research and analysis on digital IP, and analyze the market status of China, the United States, and Japan and the research on outstanding representative works in the market.

Introduction of InsurTech and Analysis of Re-Entry into Chinese Insurance Market for Korean Insurance Companies (인슈어테크 도입과 한국 보험회사의 중국 보험시장 재진출 전략 분석 연구)

  • Hwang, Ki-Sik;Choi, Sin-Young;Kim, Se-Jin
    • Journal of the Korea Institute of Information and Communication Engineering
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    • v.22 no.9
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    • pp.1147-1152
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    • 2018
  • In the recent, Chinese insurance market has taken a introduction of InsurTech. It is a combination of insurance and fintech. This means that the policyholder design their own insurance and take out the policy on-line without insurance planner. This trend is remarkable issue. Growth rate of InsurTech in China have significantly been growing. In addition, Chinese insurance market has kept generally stable and fast growth rate, although Chinese forecasting economic growth is subject to massive uncertainties. Nevertheless, the increase in the number of Korean insurance companies fails to settle into Chinese insurance market due to lack of awareness about newness of Chinese insurance market. Moreover, Korean insurance company in China or planning to enter are not prepared for InsurTech yet. Chinese insurance market is valuable for Korean insurance companies. This paper suggests implications of re-entry into Chinese insurance market to Korean insurance companies by analyzing policies which could make environment to endorse Chinese insurtech and case of Chinese insurtech companies.

A Study of the Way How Korean Fashion Brand Company Makes their Order Arrangement - Focused on fashion brand companies in Seoul - (국내 의류 브랜드 업체의 오더 의뢰방식에 관한 실태조사 - 서울시 의류 브랜드 업체를 중심으로 -)

  • Heo, Hyun-seo;Lim, Ho-sun
    • Fashion & Textile Research Journal
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    • v.21 no.2
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    • pp.179-188
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    • 2019
  • Domestic apparel products labeled as 'Made in Korea' in the Chinese market are recognized as a high quality products due to the influence of the Korean Wave (Intergen Consulting Group, 2007). This study analyzes the patterns and order arrangement types of a fashion brand company commissioned to produce apparel in Seoul, Korea in order to rebuild a network of small sewing factories scattered in Korea, reorganize operations, and to find the possibility of regenerating the Korean sewing industry by establishing contact points with domestic sewing factories. We surveyed 100 apparel brand companies in Seoul listed in the 2014/2015 Korea Fashion Brand Annual (Apparel News, 2014) and conducted a questionnaire survey on the company's general management status, type of fabric materials dealt with, and major contact points and methods of production handling. The frequency analysis indicated that the main production material with cloth type was woven fabric with ladies' clothes. The Planning MD team has the highest rate of ordering production with delivery method to the production factory after purchasing fabric and trims. Most respondents answered that they would select a production factory based on recommendations from acquaintances. This was due to a lack of no objective indicator provided by the sewing factory at present and the absence of objectively proceeded communication with brand companies. In this study, we analyze various conditions and measurements for production arrangements from a fashion brand company to revitalize sewing factories in Korea.

Influence of Job Stressors on Flourishing and Job Engagement: Comparison Between Head Office Personnel and Foreign Subsidiary Personnel (직무스트레스 요인이 번영과 직무열의에 미치는 영향: 해외진출 기업의 국내 인력과 해외 현지법인 현지 인력 간의 비교 연구)

  • Jung, Sung Cheol
    • Asia-Pacific Journal of Business Venturing and Entrepreneurship
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    • v.12 no.2
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    • pp.137-149
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    • 2017
  • This study aims to verify culture-universal invariances and culture-particular differences in the relationship of job stress, flourishing, and job engagement. For this purpose, we selected a global korean company having a local corporation in China in order to minimize the influence of organizational factor and a self-report questionnaire survey was conducted by 141 personnels of head office and 107 personnels of chinese branch. At first, the mediating effect of flourishing on the relationship between job stress and job engagement was significant for both korean and chinese personnel. Second, regression analyses were conducted in order to demonstrate influence of detailed job stress on flourishing and job engagement. As for flourishing, decision making and responsibility factor was significant for korean personnel, and lack of social support factor and job characteristic factor were significant for chinese personnel. Regarding job engagement, lack of social support factor and job characteristic factor were significant for both two samples and decision making and responsibility factor was significant for korean personnel whereas non-significant for chinese personnel. The results could give a meaningful perspectives to companies interested in extending their business abroad. Finally, implications and limitations of the study and suggestions for future research were discussed.

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Emergence and Success of Xiaomi in the Transitional Situation of Chinese Smartphone Industry

  • Kim, So Hyung
    • East Asian Journal of Business Economics (EAJBE)
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    • v.6 no.3
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    • pp.16-23
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    • 2018
  • Purpose - 2013 to 2014 was a transitional situation in which China's Smartphone industry was fluctuating. So in this paper, we will look at the strategies and achievements of Xiaomi, a company that has emerged in this situation and topped the market share. In particular, the purpose of this paper is to analyze why Xiaomi, which is considered a copycat, was able to succeed in the smartphone market four years after entering the market and analyze its strategy. Research design and methodology - Various secondary data are to be used for this study. Using various newspaper articles as well as corporate reports, the company analyzes the transitional situation from 2013 to 2014 and the competitors together. Through these analyses, Xiaomi's strengths are selected objectively and analyzed to identify the factors that made Xiaomi successful. Results - After China's transitional shift in 2014, Xiaomi brought about a 152.3 percent share change over the previous year. In addition, it surpassed Samsung Electronics, which has been the industry's No. 1 player, in 2014, and achieved the No. 1 ranking with a 16 percent share. Xiaomi Mi4's phone had a strong point of maintaining low price while being loaded with high performance. Conclusions - Xiaomi's success is because its price and performance was excellent. Xiaomi's Mi4's specifications were not far behind its competitors', but it was very cheap compared to its competitors' prices. They also valued software and used talent-oriented human resource strategies. Plus, it created the 'Mifan' culture successfully and benchmarked the strengths of its competitors smartly.

Analysis on Product Architecture and Organizational Capability of Shipbuilding Industry in South Korea and China (한·중 조선 산업의 제품 아키텍처와 조직역량에 관한 연구)

  • Baek, Seoin;Lee, Seongmin;Lee, Dukhee
    • Journal of Technology Innovation
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    • v.26 no.2
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    • pp.69-93
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    • 2018
  • As companies seek lower cost and superior quality at the same time, which depend on improvement in product architecture, they need to critically consider product architecture as part of corporate strategy. This research investigated how product architecture and organizational capability affect innovative outcomes with using architecture framework. As a result, we were able to find out Korean shipbuilding company has put much effort on integral works such as development of FGSS(Fuel gas supply system), PRS(Partial Re-liquefaction System) and weight lightening for improving fuel efficiency. And this kind of integral ability was realized by organizational capability of Korean shipbuilding company based on interactive relationship with plant workers. In contrast, Chinese shipbuilding companies focused excessively on the standard design and the convenience of research and development made by central government, overlooking the need for fine-tuning. As a result, the fuel efficiency of Chinese LNG ships turned out to be 7-10% lower than those of South Korea with using the same modules and components.

A Study on the Impact of China's Trade-related Policy Changes on Export Performance of Korean Manufacturing Companies in China (중국의 무역관련 정책 변화가 현지 진출 한국계 기업의 수출성과에 미치는 영향에 관한 연구)

  • Hong, Jae-Sung;Lee, Yong-Keun
    • International Commerce and Information Review
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    • v.16 no.1
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    • pp.69-88
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    • 2014
  • According to the previous study, after 2000s, factors of the Chinese government's trade policy changes would be a significant burden on the company. However, many previous studies were limited to the response strategy by judicial analysis. Therefore, this study aims to analyze the factors that affect the export performance of Korean manufacturing companies in China. Also, by using that result, I would like to provide advises for entered the korean companies in Chinese market As the results, I knew that export performance are most heavily influenced by labor policy factor and the fallowing is exchange rate policy factor. Eventually, Most of our country companies entering in china were affected changes in the exchange rate policy factor, but many company were manufacturing-type businesses to economize labor costs. Therefore, corporate and governmental response strategies are needed for that's companies.

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A Study on the Purpose of Patent Application by Companies: Focus on Chinese Companies (기업의 특허출원 목적에 관한 연구: 중국기업을 대상으로 21)

  • Eun-Mi Park;Seong-Taek Park
    • Journal of Industrial Convergence
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    • v.20 no.12
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    • pp.227-233
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    • 2022
  • The purpose of this research is to grasp the purpose of patent applications by companies. Based on this, we grasped the purpose of the patent application through consideration of previous research, selected 10 factors through expert Delphi, and conducted a questionnaire survey on these factors among practitioners in charge of patents in Chinese companies. Analysis results, Improve the technological image of your company, For use in negotiation: cross licensing, joint venture, Improve the situation in R&D cooperations, Enhance Reputation, Measure performance, Aacquire venture capital, Prevent patent infringement suits, Licensing Revenue, competitors' patenting and application activities, prevent copying or protect own technology from imitation. We hope that the results of this research will be useful as practical guidelines for understanding and applying factors that companies should prioritize when filing patent applications.

Operational Process and Success Factors of Corporate Venture in a Chinese Company: A Case Study of Haier (중국기업의 사내벤처 운영과정과 성공요인: 하이얼(Haier) 중심으로)

  • Yu-Rou Hou;Yuan-Jing Jin;Moon-Gu Huh
    • Asia-Pacific Journal of Business
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    • v.14 no.4
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    • pp.87-113
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    • 2023
  • Purpose - Focusing on Haier, a successful corporate venture in China, we analyse the operating mechanism and success factors of corporate venture, and reveal the necessary factors for the successful implementation of corporate venture. Design/methodology/approach - This study is a single case study centred on Haier, a successful corporate venture in China. Findings - The operational process of Haier's corporate venture includes six key aspects: project selection, team building, resource allocation and support, project implementation, risk control measures, performance evaluation and rewards. In terms of success factors, the support of top management with leadership capability of value creation and sharing is very important for the success of corporate venture. Secondly, a multi reward mechanism can be introduced to motivate employees and improve performance. Thirdly, it is important to integrate corporate culture into the operating mechanism of an corporate venture. Fourthly, flexible operations that break down rigid organisational boundaries and transform the organisation into a more open platform for entrepreneurship can increase the likelihood of success. Finally, empowering employees with operational discretion can also have a positive impact on the success of an Corporate Venture. Research implications or Originality - This study contributes to theory and practice by analysing the success conditions of corporate venture, providing new understanding and drawing new perspectives, especially from the experience of Haier. The results suggest strategies and flexibility for successfully pursuing corporate venture, and provide important experience for international companies to help them gain competitive advantage in global competition. It also helps corporate leaders to promote new directions and innovations and improve their strategies to respond to dynamic environments.