• 제목/요약/키워드: Censored survival data

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군집의 크기가 생존시간에 영향을 미치는 군집 구간중도절단된 자료에 대한 준모수적 모형 (Modeling Clustered Interval-Censored Failure Time Data with Informative Cluster Size)

  • 김진흠;김윤남
    • 응용통계연구
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    • 제27권2호
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    • pp.331-343
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    • 2014
  • 본 논문에서는 군집 구간중도절단된 자료에서 생존시간이 군집의 크기에 의존할 때 주변모형으로부터 가중 추정 방법과 군집 내 재추출 방법을 써서 모수를 추정하고 그 추정량의 점근적 성질을 살펴보았다. 모의실험을 통해 추정량의 편향의 크기와 신뢰구간의 포함율 측면에서 볼 때 제안한 두 추정 방법이 생존시간과 군집의 크기 간의 종속 관계를 무시한 방법보다 우수한 것으로 나타났다. 제안한 추정 방법을 림프성 사상충 자료에 적용한 결과에 따르면 서로 다른 두 치료방법이 유의하게 다르지 않았으며 나이 효과도 매우 유의하지 않은 것으로 나타났다.

고객 세분화에 기반한 생존분석을 활용한 고객수명 예측 모델 (Customer Lifetime Value Model Using Segment-Based Survival Analysis)

  • 전희주
    • Communications for Statistical Applications and Methods
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    • 제18권6호
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    • pp.687-696
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    • 2011
  • 고객수명은 고객생애가치(CLV)와 함께 차별화된 마케팅전략과 기업의 경쟁력 강화의 핵심수단으로 차별화된 고객관계관리(CRM) 마케팅의 매우 중요한 핵심요소이다. 그러나 보통기업에서 사용하는 고객수명은 어떤 특정시점에서의 고객에 한정하여 고객 개별적인 특성을 반영하지 않고 단순 이탈율만을 가지고 고객 수명을 예측하고 있다. 본 연구는 이러한 단점을 극복하고 현실적인 활용을 위해, 기업고객들의 중도절단자료를 가지고 고객 세분화에 기반한 생존분석을 활용한 고객수 명예측방법을 제시하고, 실제 활용을 위해 국내 A 이동통신사의 데이터를 활용하여 적용하였다. 본 연구에서 제시하고 있는 고객 세분화에 기반한 생존 분석을 이용한 고객수명 예측방법은, 첫째, 가입시점이 다른 모든고객 을반영하고 있고, 둘째, 고객의 개별적 특성을 반영하여 개별 고객수명에 대한 오차를 줄일 수 있으며, 셋째, 관측시점 이후의 수명을 예측함으로써 시간의 흐름에 따른 이탈율 또는 해지율의 변동추이를 반영하게 되어 더욱 현실성을 반영하고 있다.

Random Effects Models for Multivariate Survival Data: Hierarchical-Likelihood Approach

  • 하일도;이영조;송재기
    • 한국통계학회:학술대회논문집
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    • 한국통계학회 2000년도 추계학술발표회 논문집
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    • pp.193-200
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    • 2000
  • Modelling the dependence via random effects in censored multivariate survival data has recently received considerable attention in the biomedical literature. The random effects models model not only the conditional survival times but also the conditional hazard rate. Systematic likelihood inference for the models with random effects is possible using Lee and Nelder's (1996) hierarchical-likelihood (h-likelihood). The purpose of this presentation is to introduce Ha et al.'s (2000a,b) inferential methods for the random effects models via the h-likelihood, which provide a conceptually simple, numerically efficient and reliable inferential procedures.

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Parametric survival model based on the Lévy distribution

  • Valencia-Orozco, Andrea;Tovar-Cuevas, Jose R.
    • Communications for Statistical Applications and Methods
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    • 제26권5호
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    • pp.445-461
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    • 2019
  • It is possible that data are not always fitted with sufficient precision by the existing distributions; therefore this article presents a methodology that enables the use of families of asymmetric distributions as alternative probabilistic models for survival analysis, with censorship on the right, different from those usually studied (the Exponential, Gamma, Weibull, and Lognormal distributions). We use a more flexible parametric model in terms of density behavior, assuming that data can be fit by a distribution of stable distribution families considered unconventional in the analyses of survival data that are appropriate when extreme values occur, with small probabilities that should not be ignored. In the methodology, the determination of the analytical expression of the risk function h(t) of the $L{\acute{e}}vy$ distribution is included, as it is not usually reported in the literature. A simulation was conducted to evaluate the performance of the candidate distribution when modeling survival times, including the estimation of parameters via the maximum likelihood method, survival function ${\hat{S}}$(t) and Kaplan-Meier estimator. The obtained estimates did not exhibit significant changes for different sample sizes and censorship fractions in the sample. To illustrate the usefulness of the proposed methodology, an application with real data, regarding the survival times of patients with colon cancer, was considered.

Bayesian estimations on the exponentiated half triangle distribution under Type-I hybrid censoring

  • Kim, Yong-Ku;Kang, Suk-Bok;Seo, Jung-In
    • Journal of the Korean Data and Information Science Society
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    • 제22권3호
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    • pp.565-574
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    • 2011
  • The exponenetiated distribution has been used in reliability and survival analysis especially when the data is censored. In this paper, we derive Bayesian estimation of shape parameter and reliability function in the exponenetiated half triangle distribution based on Type-I hybrid censored data. Here we consider conjugate prior and noninformative prior and obtained corresponding posterior distributions. As an illustration, the mean square errors of the estimates are computed. Comparisons are made between these estimators using Monte Carlo simulation study.

A New Upper Bound of Convolution-type for median-Unbiased Estimators

  • So, Beong-Soo
    • Journal of the Korean Statistical Society
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    • 제28권1호
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    • pp.35-44
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    • 1999
  • We derive a new upper bound of convolution type for the median-unbiased estimators with respect to an arbitrary unimodal utility functions. We also obtain the necessary and sufficient condition for the attainability of the information bound. Applications to general MLR(Monotone Likelihood Ratio) model and censored survival data re discussed as examples.

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Survival Function Estimation for the Proportional Hazards Regression Model

  • Cha, Young Joon
    • 품질경영학회지
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    • 제18권1호
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    • pp.9-20
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    • 1990
  • The purpose of this paper is to propose the modified semiparametric estimators for survival function in the Cox's regression model with randomly censored data based on Tsiatis and Breslow estimators, and present their asymptotic variances estimates. The proposed estimators are compared to Tsiatis, Breslow, and Kaplan-Meier estimators through a small-sample Monte Carlo study. The simulation results show that the proposed estimators are preferred for small sample sizes.

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Partially Parametric Estimation of Lifetime Distribution from a Record of Failures and Follow-Ups

  • Yoon, Byoung Chang
    • 품질경영학회지
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    • 제22권4호
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    • pp.59-78
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    • 1994
  • In some observational studies, we have often random censoring model. However, the data available may be partially observable censored data consisting of the observed failure times and only those nonfailure times which are subject to follow up. In this paper, we present an extension of the problem of partially parametric estimation of the survival function to such partially observable censored data. The proposed estimator treats the observed failure times nonparametrically and uses a parametric model only for those nonfailure times which are subject to follow-up. We discuss the motivation and construction of the proposed estimator and investigate the limiting properties of the proposed estimator such as asymptotic normality. Also, when the assumed parametric model is exponential, the asymptotic variance of the estimator is obtained. Furthermore, an example is given to compare the proposed estimator with the modified Kaplan Meier(MKM) estimator. From the results, it is shown that the relative efficiency of the proposed estimator is higher than that of the MKM estimator in the follow-up study with increasing time.

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Goodness of Fit Tests of Cox's Proportional Hazards Model

  • Song, Hae-Hiang;Lee, Sun-Ho
    • Journal of the Korean Statistical Society
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    • 제23권2호
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    • pp.379-402
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    • 1994
  • Graphical and numerical methods for checking the assumption of proportional hazards of Cox model for censored survival data are discussed. The strenths and weaknessess of several goodness of fit tests for the propotional hazards for the two-sample problem are evaluated with Monte Carlo simulations, and the tests of Schoenfeld (1980), Andersen (1982), Wei (1984), and Gill and Schumacher (1987) are considered. The goodness of fit methods are illustrated with the survival data of patients who had chronic liver disease and had been treated with the endoscopy injection sclerotheraphy. Two other examples of data known to have nonpropotional hazards are also used in the illustration.

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Comparison of missing data methods in clustered survival data using Bayesian adaptive B-Spline estimation

  • Yoo, Hanna;Lee, Jae Won
    • Communications for Statistical Applications and Methods
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    • 제25권2호
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    • pp.159-172
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    • 2018
  • In many epidemiological studies, missing values in the outcome arise due to censoring. Such censoring is what makes survival analysis special and differentiated from other analytical methods. There are many methods that deal with censored data in survival analysis. However, few studies have dealt with missing covariates in survival data. Furthermore, studies dealing with missing covariates are rare when data are clustered. In this paper, we conducted a simulation study to compare results of several missing data methods when data had clustered multi-structured type with missing covariates. In this study, we modeled unknown baseline hazard and frailty with Bayesian B-Spline to obtain more smooth and accurate estimates. We also used prior information to achieve more accurate results. We assumed the missing mechanism as MAR. We compared the performance of five different missing data techniques and compared these results through simulation studies. We also presented results from a Multi-Center study of Korean IBD patients with Crohn's disease(Lee et al., Journal of the Korean Society of Coloproctology, 28, 188-194, 2012).