• JSTS:Journal of Semiconductor Technology and Science
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• 제11권2호
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• pp.111-120
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• 2011

A two-dimensional analytical model for deriving the threshold voltage of a short channel fully depleted (FD) cylindrical/surrounding gate MOSFET (CGT/SGT) is suggested. By taking into account the lateral variation of the surface potential, introducing the natural length expression, and using the Bessel functions of the first and the second kinds of order zero, we can derive potentials in the gate oxide layer and the silicon core fully two-dimensionally. Making use of these potentials, the minimum surface potential can be obtained to derive the threshold voltage as a closed-form expression in terms of various device parameters and applied voltages. Obtained results can be used to explain the drain-induced threshold voltage roll-off of a CGT/SGT in a unified manner.

• 미생물학회지
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• 제44권1호
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• pp.74-79
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• 2008

L-ascorbic acid (AA)의 2번 위치의 수산기에 부위 특이적 활성을 갖는 Paenibacillus sp. JB-13 유래의 cyclodextrin glucanotransferase (CGTase, EC 2.4.1.19) 유전자(cgt gene)를 pEXP7 발현 vector에 클로닝하여 재조합 균주를 구축하였다. 재조합 균주의 CGTase생산 최적 조건을 검토하여 본 결과 LB 배지에 0.5% glucose, 3.0% polypeptone, 0.3% $K_2HPO_4$, 0.5% NaCl이 되도록 추가하고, 초기 pH 7.0, 접종량 2%, 통기량 0.1 vvm, 배양 온도 $37^{\circ}C$, 배양 시간 14시간의 조건에서 최대 활성을 나타내었다. 재조합 균주와 기존 균주의 CGTase 활성을 비교한 결과 재조합 균주는 배양 14시간째 640 units/ml의 활성을 가져 기존 균주에 비해 70%의 활성을 나타내지만 배양 시간을 1/4로 단축시킬 수 있다는 이점이 있음을 확인하였다. 재조합 균주가 생산한 CGTase를AA-2G합성에 적용하여 AA-2G를 합성하고 HPLC로 분석한 결과 단일 peak를 확인할 수 있었고 ${\alpha}$-glucosidase를 처리하여 확인한 결과 AA와 glucose로 분리됨을 확인할 수 있었다.

• 생명과학회지
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• 제14권3호
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• pp.391-395
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• 2004

B. stearothermophilus NO2의 CGTase 유전자 (cgtS)를 구성적 $P_{JH}$ promoter 하류에 subcloning 하여 재조합 plasmid pIH-CGT1 (8.14 kb)을 구축하고 B. subtilis DB431에 형질 전환하였다. B. subtilis DB431/pJH-CGT1를 5가지 배지(LB, 2${\times}$LB, 5% molasses+2% CSL, CS, LBG)로 flask 배양하여 균체증식과 CGTase발현량 및 분비국재성을 조사하여 최적 배지를 결정하였다. 그 중 〔5% molasses+2% CSL〕 배지에서 9시간에 1.8 unit/$m\ell$의 CGTase가 발현$.$생산되었다. 이 결과를 토대로 3. subtilis DB431/pJH-CGT1를 〔10% molasses + 5% corn steep liquor〕 배지에서 발효조 회분 배양한 결과, 30시간 배양시 CGTase의 최대 발현량은 4.2 unit/$m\ell$, 90%의 분비 효율, 90% 이상의 plasmid 안정성을 나타내었다. 저렴한 산업용 molasses 배지로 발효조 회분배양시 플라스크 배양보다 균체증식과 CGTase 발현량이 2배 이상의 증가된 값을 얻었다.

• 대한원격탐사학회지
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• 제40권3호
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• pp.285-293
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• 2024

본 연구는 Google Earth Engine을 활용하여 Sentinel-1 Synthetic Aperture Radar 영상을 통해 남극 Campbell Glacier Tongue (CGT)와 Drygalski Ice Tongue (DIT)의 면적 변화를 2016년부터 2024년까지 모니터링하였다. Otsu 기법과 Simple Non-Iterative Clustering (SNIC) 클러스터링 기법을 사용하여 빙설과 해양을 구분하고 월평균 영상을 통해 빙설 탐지 오류를 줄였다. 분석 결과 CGT는 주기적인 붕괴로 인하여 약 26% 감소하였고 DIT는 전반적으로 증가하다가 최근 급격한 감소를 보였다. Sentinel-2 광학 영상과 비교한 결과 높은 탐지 정확성을 보여 제안된 방법의 신뢰성을 입증하였으며, 본 연구는 남극 빙설과 빙붕의 장기 모니터링에 기여할 것으로 기대된다.

• JSTS:Journal of Semiconductor Technology and Science
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• 제12권4호
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• pp.458-466
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• 2012

A Dual metal gate stack cylindrical/ surrounded gate MOSFET (DMGSA CGT/SGT MOSFET) has been proposed and an analytical model has been developed to examine the impact of this structure in suppressing short channel effects and in enhancing the device performance. It is demonstrated that incorporation of gate stack along with dual metal gate architecture results in improvement in short channel immunity. It is also examined that for DMGSA CGT/SGT the minimum surface potential in the channel reduces, resulting increase in electron velocity and thereby improving the carrier transport efficiency. Furthermore, the device has been analyzed at different bias point for both single material gate stack architecture (SMGSA) and dual material gate stack architecture (DMGSA) and found that DMGSA has superior characteristics as compared to SMGSA devices. The analytical results obtained from the proposed model agree well with the simulated results obtained from 3D ATLAS Device simulator.

• Plant Resources
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• 제5권3호
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• pp.169-175
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• 2002

The soybean cyst nematode (Heterodera glycines Inchinoe; SCN) is a devastating pest of soybean and is responsible for significant losses in yield. The use of resistant cultivars is the effective method to reduce or eliminate SCN damage. The objective of this research is to identify AFLP markers linked to the SCN resistant genes. Bulked genomic DNA was made from resistant and susceptible genotypes to SCN and a total of 19 primer combinations were used. About 31 fragments were detected per primer combination. The banding patterns were readily distinguished in resistant and susceptible bulked genotypes. Polymorphic fragments were detected between resistant and susceptible bulked genotypes in the primer combination of CGT/GGC, CAG/GTG and CTC/GAG. In primer combinations of CGT/GGC and CAG/GTG, bulked resistant genotype produced a polymorphic bands. However, in primer of CTC/GAG, bulked susceptible genotype produced a polymorphic fragments. Three AFLP markers identified as a polymorphic fragments between bulked genomic DNA were mapped in 85 F2 population. Among them, only two markers, CGT/GGC and CTC/GAG, was linked and was mapped. Broad application of AFLP marker would be possible for improving resistant cultivars to SCN.

• 대한한방소아과학회지
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• 제33권3호
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• pp.103-111
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• 2019

Objectives The purpose of this study is to understand the correlations between lung, large intestine, and skin of 3-week-old mice in which ulcerative colitis was induced, up on administration of Coptidis rhizome and Glycyrrhiza uralensis mixed extract. Methods Mice were divided into 4 groups as follows; no treatment group (Ctrl group), ulcerative colitis-induced mice group (UE group), ulcerative colitis-induced mice group after administering Pentasa (PT group), ulcerative colitis-induced mice group after administering Coptidis rhizoma and Glycyrrhiza uralensis mixed extract (CGT group). Mice were induced ulcerative colitis by Dextran sulfate sodium (DSS). After 5 days of administration, We obvserved anti-inflammatory effect, alveolar formation, and skin barrier control in the colon mucosa. Results The CGT group was observed arrangement of normal intestinal cells, Infiltration of less inflammatory cells. The CGT significantly decreased positive rseponse of $TNF-{\alpha}$, p-IkB, Caspase 3 in large intestine, and significantly increased positive rseponse of EGF, IGF, catalase, Filaggrin, involucrin, loricrin. Conclusions The results of this study show the correlation of Lung-Large intestine-Skin by administering Coptidis rhizoma and Glycyrrhiza uralensis mixed extract to ulcerative colitis-induced mice.

• 한국작물학회지
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• 제59권3호
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• pp.341-349
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• 2014

경실로 인해 다른 두과작물에 비해 포장 입묘가 불량한 팥의 포장출현율의 효과적인 예측 방법을 개발하기 위해 인위로 노화 정도를 조절한 종자에 대해 실험실에서 몇 가지 종자세 검사를 실시하여 포장출현력과 비교하였다. 얻어진 종자세 지표들에 대해 포장출현력과의 상관분석을 통해 예측을 위한 효율적인 지표들을 도출하였다. 팥에서 종자세가 높을 경우에는 표준발아검사에서의 종자활력률이 포장출현력 예측에 효과적이며, 약간 노화된 종자의 경우에는 저온발아검사(CGT)에서의 비정상묘율과 배축의 길이는 포장출현력과 높은 상관관계를 보였으며, 전기전도도와 CSVT에서의 활력률과 테트라졸리움 검사에서 종자세와 예측발아율은 포장출현력과 5% 수준에서 상관관계가 인정되었다. 종자세가 낮은 종자에서는 CSVT에서 불발아종자율이 포장출현력과 5% 수준에서 상관을 보였다. 포장출현력 예측에 효과적인 몇 가지 종자세지수를 이용하여 stepwise multiple regression 분석을 실시한 결과 테트라졸리움(TZ) 검사에서의 예측발아율은 결정계수($R^2$)가 0.820으로 포장출현력 예측에 가장 효과적인 검사방법임을 알 수 있었다. 표준발아검사(SGT)에서의 종자활력률, 저온발아검사(CGT)에서의 정상묘율과 건물중을 회귀방정식에 추가함에 따라 86.9% 까지 포장출현력 예측효율을 증가시킬 수 있었다.

• 대한한방소아과학회지
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• 제31권3호
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• pp.14-23
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• 2017

Objectives This study is conducted to evaluate skin fat barrier formation of Hataedock using the Coptis japonica & Glycyrrhiza uralensis extract. Methods The 3-week-old NC/Nga mice were divided into 3 groups: control group (Ctrl), Hataedock-treated group that uses the Coptis japonica & Glycyrrhiza uralensis (CGT) extract, and Hataedock-treated group that uses Bifidobacterium (BBT). After 2 weeks, changes in immunohistochemicals, and skin-lipid-barrier regulators were observed for the effects of Hataedock. Results In CGT group, loricrin-positive reaction has been increased by 231%, along with involucrin-positive reaction by 90%, filaggrin-positive reaction by 143%, and ASM-positive reaction by 341% in the stratum corneum. Conclusions Hataedock, using the extract of Coptis japonica & Glycyrrhiza uralensis, increased the expression of proteins promoting keratinocyte differentiation. This leads into conclusion that Hataedock may increase the keratinocyte formation and function which promotes skin barrier formation.

• 제어로봇시스템학회:학술대회논문집
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• 제어로봇시스템학회 1994년도 Proceedings of the Korea Automatic Control Conference, 9th (KACC) ; Taejeon, Korea; 17-20 Oct. 1994
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• pp.189-194
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• 1994

Adaptive control systems based upon the command generator tracker(CGT) approach have attracted considerable interest because of the simple structure of its adaptive controller. Some attempts to such improve the adaptive control algorithm, for the sake of the application to broader class of plants, are made. Recently, Su and Sobel(1992) proposed that those schemes can be treated by an unified theory using a metasystem representation with some types of supplementary dynamics. However, in their method, it is difficult to find the dynamic compensator, which is proper and output feedback stabilizable, for the uncertain plant. This paper proposes a new design method of such supplementary dynamics and some parameters of adaptive control system for linear time invariant SISO plants. The method gives a concrete and systematic design method using only a few priori knowledge of the plant.