• Title/Summary/Keyword: CCI₄

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Effects of Godulbaegi(Ixeris Sonchifolia H.) Diets on Enzyme Activities of CCI4 Induced Hepatotoxicity in Rats (고들빼기 식이가 간 독성을 유발한 흰쥐의 효소 활성에 미치는 영향)

  • 배송자
    • Journal of Nutrition and Health
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    • v.30 no.1
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    • pp.19-24
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    • 1997
  • This study was carried out to investigate the effects of enzyme activities on male Sprague-Dawley rats intoxicated by CCI4 on IS(Godulbaegi) diets for 4 weeks. We divides into 5 diet groups which were normal diet(N), normal diet intoxicated by CCI4(NC) and 3 IS diets ; leaves diet(ILC), roots diet(IRC) and mixed diet of leaves and roots which were also injected by CCI4 3 times for 4 weeks. The activity of glutamic pyruvic transaminase(GPT) in serum in NC was higher than in N as we expected. The GPT activites and the values of malondial-dehyde(MDA) of IS groups were all lower than in NC, IC as lowest. The activity of superoxide dismutase(SOD) in NC was higher than in N and IS groups had values less than the values of N. Catalase showed similarity in results as above. The values of glutathione S-transferase(GST) and cytochrome P-450 in NC were lower than in N. IS groups had higher values than in NC. Godulbaegi might be important not only as one of the traditional Korean foods but also as therapeutic agent for hepatotoxicity and for shortening the recovery time in liver disease.

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Effects of Solanum lyratum on The $CCl_4$-indused$ Liver Damage in mice (배풍등(排風藤)이 $CCl_4$ 유발된 mouse의 간손상(肝損傷)에 미치는 영향)

  • Park Chul-Soo;Lee Won-Hoon;Kim Seon-Kang;Kim Jong-Dae;Park Seon-Dong
    • Herbal Formula Science
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    • v.8 no.1
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    • pp.129-146
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    • 2000
  • This study was carried out to investigate the effects of Solanum lyratum Extract (SLE) on the recovery of liver in $CCI_{4}-intoxicated$ mice. In this study, ICR-Mice were divided into 3 experimental groups; Normal group was fed basal diet and was fed bassal diet for 2 Weeks, sample group was injected $CCl_{4}\;(0.6m{\ell}/kg)$ and was fed basal diet for 2 weeks, sample group was injected $CCl_{4}\;(0.6m{\ell}/kg)$ and was fed the SLE 500mg/kg fod 2 Weeks. In sample group, the level of serum AST, ALT, ALP activity decreased significantly compared with control group. This results suggest that SLE has appreciable therapeutic effect on $CCI_4$ induced hepatotoxicity. In sample group, the level of LPO in liver homogenates decreased significantly compared with control group. In sample group. the level of GSH, catalase in liver homogenates increased significantly compared with control group. This results suggest that SLE has appreciable antioxidant effect on $CCI_4induced hepatotoxicity. In conclusion the results suggest that SLE has appreciable therapeutic effect and antioxidant effect on $CCI_4$ induced hepatotoxicity.

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Co-Channel Interference Cancellation in Cellular OFDM Networks - PART I : Maximum-Likelihood Co-Channel Interference Cancellation with Power Control for Cellular OFDM Networks

  • Mohaisen, Manar;Chang, Kyung-Hi
    • The Journal of Korean Institute of Communications and Information Sciences
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    • v.32 no.5A
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    • pp.409-416
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    • 2007
  • In cellular orthogonal frequency division multiplexing (OFDM) networks, co-channel interference (CCI) leads to severe degradation in the BER performance. To solve this problem, maximum-likelihood estimation (MLE) CCI cancellation scheme has been proposed in the literature. MLE CCI cancellation scheme generates weighted replicas of the transmitted signals where weights represent the estimated channel transfer functions. The replica with the smallest Euclidean distance from the received signal is selected and data are detected. When the received power of the desired and interference signals are nearly the same, the BER performance is degraded. In this paper, we propose a closed-loop power control (PC) scheme capable of detecting the equal received power situation at the mobile station (MS) receiver by using the newly introduced parameter power ratio (PR). When this situation is detected, the MS sends a feedback to the desired base station (BS) which boosts the transmission power in the next frame. At cell edge where signal to interferer ratio (SIR) is considered to have average value between -5 dB and 10 dB, computer simulations show that the proposed CCI cancellation scheme has a gain of 7 dB at 28 Km/h.

Performance Analysis on the Narrowband Interference Rejection of Impulse Radio System in Frequency Coexistence Environment (주파수 공존 환경에서 Impulse Radio 시스템의 협대역 간섭 제거 성능 분석)

  • Jang, Se-In;Lee, Yang-Sun;Kim, Si-Gwan
    • Journal of Advanced Navigation Technology
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    • v.14 no.5
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    • pp.745-751
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    • 2010
  • In this paper, the proposed a narrowband interference cancellation techniques for the frequence sharing of Ultra wideband Impulse Radio communication system and narrowband communication system. In this system, the narrowband communication signals can cause intolerant interferences to Impulse Radio signals. In this paper, Ultra wideband Impulse Radio system have been analyzed in AWGN, MAI and NI(Narrowband Interference) environment. Also, performance improvement has been obtained by adopting an adaptive notch filtering scheme using Complex Filter Bank and CCI canceller. The results show that there is a substantial enhancement in performance by employing the adaptive notch filtering and/or CCI canceller.

Effect and Histopatbologic Examination of Calcium Channel Blocker on Carbon Tetrachloride-induced Hepatotoxicity in Rats (Calcium Channel Blocker가 사염화탄소에 의한 간손상에 미치는 영향 및 조직학적 검경)

  • 전명애;정춘식;정기화
    • Biomolecules & Therapeutics
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    • v.6 no.3
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    • pp.247-255
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    • 1998
  • Carbon tetrachloride (CCI$_4$) induces the hepatotoxicity due to the reactive free radicals generated by cytochrome P-450 (CYP-450) enzyme, which result in destabilization of cellular membrane. Diltiazem, a calcium channel blocking agent, has been known to suppress the CYP-450 enzyme activities. To study the effect of diltiazem in $CCl_4$-treated rats, we measured the activities of alanine aminotransferase (ALT), aspartate aminotransferase (AST) and glutathione S-transferase (GST), contents of bilirubin, albumin, total protein, cholesterol, triglyceride, blood urea nitrogen, creatinine malondialdehyde and calcium. Also we conducted liver histopathologic examinations. Diltiazem, when administered 1 hour prior to CCI$_4$ treaeent, significantly reduced the activities of ALT and AST, the contents of microsomal malondialdehyde and calcium in liver and microsome as compared with those of $CCl_4$-treated rats. In addition, histopathologic examination showed that diltiazem prevented the development of centrilobular necrosis induced by CCI$_4$ in liver tissue. Our results suggested that diltiazem could inhibit the formation of free radicals and the influx of calcium. Therefore diltiazem may be applied to suppress the liver damage caused by $CCl_4$.

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Synthesis and Charaterization of Poly(styrene-b-methyl Methacrylate) by Free Radical Telomerization (Ⅰ) (자유라디칼 Telomerization 에 의한 스티렌메타크릴산메틸 Block 혼성중합체의 합성 및 분석 (제1보))

  • Jung Hag Park;Gil Soo Sur;Sam Kwon Choi
    • Journal of the Korean Chemical Society
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    • v.24 no.3
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    • pp.259-265
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    • 1980
  • Poly (styrene-b-methyl methacrylate) (PS-b-PMMA) was synthesized by free radical telomerization: the telomerization of styrene with $CCI_4$ by using AIBN as initiator followed by a second telomerization of methyl methacrylate using $CCI_3$ end group of the resulting polymer as the macrotelogen, with AIBN initiation, gave the styrene-methyl methacrylate block copolymer. The effects of the concentration of the macrotelogen, the concentration of monomer, the molecular weight of the macrotelogen, the reaction temperature and the concentration of the solvent on the formation of the block copolymer were investigated. Block copolymers containing up to 10 weight percent PMMA were obtained by adjusting the reaction conditions.

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Performance improvement of the DS-CDMA/DPSK cellular mobile communication system with CCI canceller and RAKE receiver (DS-CDMA/DPSK 셀룰라 이동통신 시스템에서 간섭 제거기와 RAKE 수신기에 의한 성능 개선)

  • 이경준;오창헌;조성준;채수환
    • Journal of the Korean Institute of Telematics and Electronics A
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    • v.33A no.4
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    • pp.37-46
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    • 1996
  • In this paper, we analyzed the performance improvement of the DS-CDMA/dPSK cellular mobile communication system with CCI canceller and RAKE receiver techniques in mobile radio channel which is characterized by AWGN, Multi-user interference (mUI) and frequency-selective rayleigh fading. System capacity i.e., number of user per cell has been derived and the evaluated results are shown in figuraes as a function of PN code sequence length, number of RAKE receiver tap, BER and E$_{b}$/N$_{o}$. The voice activity factor is assumed to be 3/8 the number of sectors in a cell 3 and MUI is modeled as gaussian process. From the results, the capacity of the DS-CDMA/DPSK cellular mobile communication system is improved by adopting CCI canceller. When we adopt the RAKE receiver to mitigate the multipath fading, the error performance is improved and the amount of improvement is proportional ot the number of taps L in the case that each tap contains a signal component and the better of improvement can be obtained, the smaller of the SNR difference in each tap. The system capacity is more increased when the CCI canceller and the RAKE receiver is used in cascade.

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Performance of MIMO-OFDM systems with multi-beamforming based on MMSE (MMSE 기반의 다중 빔형성기법을 가진 MIMO-OFDM 시스템의 성능)

  • Kim, Chan-Kyu
    • Journal of the Institute of Electronics Engineers of Korea TC
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    • v.48 no.6
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    • pp.6-13
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    • 2011
  • Multiple-input multiple-output (MIMO)-orthogonal frequency division multiplexing (OFDM) with space-time coding (STC) is a promising technology for future wireless communication systems. However, MIMO-OFDM systems are greatly impaired by large cochannel interference (CCI) from the multiple transmitters. In this paper, we propose pre-fast Fourier transform (FFT) multibeamforming based on MMSE(minimizing the mean squared error) for a MIMO-OFDM system to preserves the STC diversity and to remove the CCI. The improvement in bit error rate is investigated through computer simulation of a MIMO-OFDM system in a multipath channel with CCI.

Co-channel Interference Reduction using Multi code MC-CDMA in Visual Light Communication System (가시광 통신 환경에서 Multi code MC-CDMA를 통한 동일 채널 간섭 감쇄 기법)

  • Lee, Kyujin;Kim, Guijung
    • Journal of Digital Convergence
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    • v.12 no.8
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    • pp.249-255
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    • 2014
  • In this paper, we proposed to reduce the interference in the visible light Communication with multi-LEDs for improving the performance of BER and satisfied the QoS. LED is not only lighting device, but also transmitting device in the VLC. Our proposed system is aim to decrease the interference in the multi-LEDs. In addition, it occurred the ISI and CCI by transmitter to receiver different distance. To solve this problem, we proposed the multi-LEDs system using walsh code to reduce ISI and CCI. In addition, our proposed system is able to improve the performance of BER and satisfied the Qos to desire users.

Effect of Acua-acupuncture with soshiho-tang at Kansu($BL_{18}$) and Tamsu($BL_{19}$) on Recovery Liver function in Rat with $CCl_4$ (간유(肝兪), 담유(膽兪)의 소시호탕(小柴胡湯) 약침처리(藥鍼處理)가 $CCl_4$ 중독(中毒) Rat의 간기능회복(肝機能恢復)에 미치는 영향(影響).)

  • Oh, Se-Woong;Lee, Joon-Moo
    • The Journal of Korean Medicine
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    • v.16 no.1 s.29
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    • pp.271-280
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    • 1995
  • Effects of aqua-acupuncture with soshiho-tang at Kansu(BL_{18}$) and Tamsu(BL_{19}$) on the Glutamic Oxaloacetic Transaminase(GOT), Glutamic Pyruvic Transaminase(GPT), Lactic dehydrogenase(LDH) and blood pictures in rat with $CCI_4$ were determined. In the group with $CCI_4$ the activity of GOT, GPT and LDH showed a tendency to increase, however these values showed a tendency to decrease by the aqua-acupuncture with soshiho-tang throughout experimental days and these values were recovered to those of control group on the last experimental days. Counts of RBC and Hemoglobin showed a tendency to decrease in rat with $CCI_4$, however these decreased values were recovered by the aqua-acupuncture with soshiho-tang and on the last experimental days, these values were similar to those of control group. In the $CCI_4$ group, counts of WBC and the proportion of Lymphocytes showed a tendency to increase and the proportion of Neutrophils showed a tendency to decrease, however these values showed a rapid recovery by the aqua-acupuncture with soshiho-tang. In the meridian point of Kansu and Tamsu, the effects of aqua-acupuncture with soshiho-tang on recovery of liver function showed no difference. Results from this study indicate that the aqua-acupuncture with soshiho-tang can improve the liver function in rat with $CCI_4$.

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