• 대한치과교정학회지
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• 제36권2호
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• pp.103-113
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• 2006

중년 이후의 여성의 경우 칼슘 섭취가 부족하거나, 인위적인 난소 적출 또는 폐경 등으로 인하여 골밀도가 감소하는 경향이 있다. 이 경우 교정 치료 시, 골내 고정원으로 마이크로스크류를 이용할 수 있는지를 알아보기 위하여, 생후 4개월 된 Sprague-Dawley계 백서를 실험군으로 난소 적출(Ovariectomy Screw, OS)군, 대조군으로 Sham operation 시행한(Sham operation Screw, SS) 군의 두 군으로 나누었다. OS군과 SS군 모두 상악 대구치 사이 구개골에 마이크로스크류를 식립하였고, NiTi coil spring을 이용하여, 상악 중절치 2개를 견인하였다. 각 군당 3일, 7일 후 7마리씩 희생시켰다. 희생 3일전 Alizarin red S를 주입하고, 상악골, 장골, 심장혈을 채득한 후, 심장혈을 성분분석하고, 상악골과 장골은 비탈회 레진표본을 제작하여, 편광현미경, 형광현미경으로 관찰하였다. 심장혈을 통한 성분 조사 결과 OS군, SS군 모두 7일째 alkaline phosphatase (ALP)의 농도가 높게 나타나 골개조의 가능성을 보였고, 편광현미경 사진에서 SO, SS군에서 모두 마이크로스크류의 압박측, 긴장측, 치아의 긴장측에서 3일 보다 7일에서 기존골에 비하여 골밀도가 낮은 영역이 적었고, 치아의 압박측에서는 골밀도가 낮은 영역이 증가하였다. 형광 현미경 관찰결과는 3일째 보다 7일째에 더 Alizarin red S로 침착된 골이 나타난 것으로 보아, 새로운 골의 형성이 있었음을 나타내었다. 골다공증이 유도된 백서에서 계속된 골의 흡수보다는 골개조의 가능성이 증가하고, 신생골의 형성이 증가함을 확인할 수 있었고, 이는 골다공증에서도 마이크로스크류의 식립으로 고정원 확보가 가능한 것으로 생각한다.

• Journal of Korean Neurosurgical Society
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• 제49권6호
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• pp.351-354
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• 2011

Objective : This investigation was conducted to evaluate a new, safe entry point for the C2 pedicle screw, determined using the anatomical landmarks of the C2 lateral mass, the lamina, and the isthmus of the pars interarticularis. Methods : Fifteen patients underwent bilateral C1 lateral mass-C2 pedicle screw fixation, combined with posterior wiring. The C2 pedicle screw was inserted at the entry point determined using the following method : 4 mm lateral to and 4 mm inferior to the transitional point (from the superior end line of the lamina to the isthmus of the pars interarticularis). After a small hole was made with a high-speed drill, the taper was inserted with a 30 degree convergence in the cephalad direction. Other surgical procedures were performed according to Harm's description. Preoperatively, careful evaluation was performed with a cervical X-ray for C1-C2 alignment, magnetic resonance imaging for spinal cord and ligamentous structures, and a contrast-enhanced 3-dimensional computed tomogram (3-D CT) for bony anatomy and the course of the vertebral artery. A 3-D CT was checked postoperatively to evaluate screw placement Results : Bone fusion was achieved in all 15 patients (100%) without screw violation into the spinal canal, vertebral artery injury, or hardware failure. Occipital neuralgia developed in one patient, but this subsided after a C2 ganglion block. Conclusion : C2 transpedicular screw fixation can be easily and safely performed using the entry point of the present study. However, careful preoperative radiographic evaluation, regardless of methods, is mandatory.

• Journal of the Korean Association of Oral and Maxillofacial Surgeons
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• 제29권6호
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• pp.379-391
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• 2003

The present study was undertaken to evaluate bone regenerative capacity around titanium screw implants placed in irradiated rat's tibiae. At one week after single 15-Gy dose irradiation, miniaturized titanium screw implants were inserted into anterior aspect of the upper tibia of rats weighing 200-250g. Seventy rats were involved: 35 rats were control and 35 rats radiation group. The rats were killed at different intervals as 1, 2, 3, 4, 6, 8, 12 weeks after implantation for histologic observation, histomorphometric analysis and immunohistochemical study with fibronectin and CD34 antibody. 1. Histologically, various stages of bone maturation and ossification can be seen at 4 weeks and regenerated bone close to edges demonstrates more advanced calcification, and network of new bone are well formed at 12 weeks in non-irradiated group. In contrast, active bone formation with increased contact of newly formed bone to implant surface was noted at 4 weeks and a significant amount of new bone formation and bone-implant contact is oberved at 12 weeks in irradiated group. 2. Histomorphometrical analysis confirmed these histologic findings. A significant difference in implant-bone contact and bone density was measured between the control and radiation group. Mean MBD was 62.2% in control group and 27.5% in radiation group, mean MBIC was 86.6% in control group and 47.7% in radiation group, and mean TBIC was 87.3% in control group and 45.6% in radiation group at 12 weeks after implantation. 3. In immunohistochemical study with fibronectin and CD34, radiation reduced hematopoietic progenitor cells severely and disturbed differentiation of osteoblast in bone marrow. The results of this study revealed bone healing capacity around implant after radiation therapy was severely impaired and irradiation reduces the capacity for osseointegration of titanium implants. Many factors including radiation dose, period between radiation and implantation, bone quality, time elapse between first and second surgery, type of prosthetics and hyperbaric oxygen therapy must be considered carefully in postradiation implantation.

• 구강회복응용과학지
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• 제19권4호
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• pp.257-268
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• 2003

The purpose of this study was to assess the loading distributing characteristics of implant prosthesis according to position and direction of load, under vertical and inclined loading using FEA analysis. The finite element model was designed according to standard fixture (4.1mm restorative component x 11.5mm length). The crown for mandibular first molar was made using UCLA abutment. Each three-dimensional finite element model was created with the physical properties of the implant and surrounding bone. This study simulated loads of 200N at the central fossa in a vertical direction (loading condition A), 200N at the outside point of the central fossa with resin filling into screw hole in a vertical direction (loading condition B), 200N at the centric usp in a $15^{\circ}$ inward oblique direction (loading condition C), 200N at the in a $30^{\circ}$ inward oblique direction (loading condition D) or 200N at the centric cusp in a $30^{\circ}$ outward oblique direction (loading condition E) individually. Von Mises stresses were recorded and compared in the supporting bone, fixture, and abutment screw. The following results have been made based on this study: 1. Stresses were concentrated mainly at the ridge crest around implant in both vertical and oblique loading but stresses in the cancellous bone were low in both vertical and oblique loading. 2. Bending moments resulting from non-axial loading of dental implants caused stress concentrations on cortical bone. The magnitude of the stress was greater with the oblique loading than with the vertical loading. 3. An offset of the vertical occlusal force in the buccolingual direction relative to the implant axis gave rise to increased bending of the implant. 4. The relative positions of the resultant line of force from occlusal contact and the center of rotation seems to be more important. 5. The magnitude of the stress in the supporting bone, fixture and abutment screw was greater with the outward oblique loading than with the inward oblique loading and was the greatest under loading at the centric cusp in a $30^{\circ}$ outward oblique direction. Conclusively, this study provides evidence that bending moments resulting from non-axial loading of dental implants caused stress concentrations on cortical bone. But it seems to be more important that how long is the distance from center of rotation of the implant itself to the resultant line of force from occlusal contact(leverage). The goal of improving implants should be to avoid bending of the implant.

• 한국임상수의학회지
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• 제39권2호
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• pp.59-64
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• 2022

A dog aged two years and seven months and a cat aged seven years were referred owing to fractures of long bones. Preoperative radiographs revealed comminuted bone fractures close to joints. Conventionally, long-bone fractures are treated using intramedullary pins, plate and screw systems, or an external fixator system. In cases of non-reducible fractures, various graft materials have been used in fracture treatments to stimulate bone repair. Here, recombinant human bone morphogenetic protein-2 (rhBMP-2) and a collagen membrane were applied. Four weeks after surgery, fractured bone fragments began to unite and the bone union was observed using radiography four months after surgery. No complications occurred related to grafted materials. We successfully applied rhBMP-2 and collagen membranes in two different species to support the healing process of comminuted fractures, according to the concept of guided bone regeneration.

• 대한치과교정학회지
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• 제37권2호
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• pp.89-97
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• 2007

교정용 스크류의 적절한 식립 토오크는 스크류와 골과의 경계에 적절히 작용하여 실패를 최소화 할 수 있는데, 너무 낮은 식립 토오크는 안정성이 없으며 반면에 너무 강한 식립 토오크는 열, 기계적 손상으로 골 괴사를 야기할 수도 있다. 본 연구에는 임상적으로 스크류의 길이와 직경 및 형태 등을 달리하여 식립 토오크를 측정해서 스크류의 각 부분에 대한 세분화된 토오크의 변화를 분석하고자 하였다. 연구결과 1.5 mm 두께의 인공피질골 블록에서 cylindrical type 스크류와 taper type 스크류 두 형태 모두에서 스크류 길이가 길수록 최대 식립 토오크 값도 함께 증가하였다. 특히 cylindrical type 스크류에서 길이에 따른 토오크 변화에 대해 통계적으로 유의한 차이가 관찰되었다 (p<0.05). 미니스크류의 연속적인 식립 토오크 분석 결과 cylindrical type 스크류는 연속적인 그래프 형태를 보이면서 불완전 나사부에서 식립 토오크가 크게 증가하였으며, taper type 스크류는 나사선의 마지막 경사진 부분에서 식립 토오크가 크게 증가하였다. 외경이 커질수록 최대 식립 토오크 값은 증가하였는데, 통계적으로 유의한 차이를 보였다 (p<0.05). 형태와 외경, 길이는 모두 토오크 값에 유의한 영향을 미치는데, 식립 토오크에 가장 큰 영향을 미치는 것은 외경, 형태, 길이 순서였다. 본 연구 결과 스크류의 식립 토오크에 가장 큰 영향을 미치는 것은 스크류의 외경이며 각각의 해부학적 구조물에 대한 피질골의 두께를 고려하여 적합한 스크류의 두께 및 나사산의 형태를 선택하는 것이 스크류의 초기 고정력을 얻는데 유리하다고 판단된다.

• Clinics in Shoulder and Elbow
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• 제23권4호
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• pp.198-202
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• 2020

Simple clavicle fractures can achieve satisfactory results through conservative treatment, and the less frequency of nonunion. Non-union or malunion can occur in displaced clavicle fractures or comminuted shaft fractures. Treatment of displaced comminuted clavicle shaft fractures is performed by holding together the free fragments with interfragmentary screws or wires and fixing them to the clavicle with a plate. Therefore, we performed interfragmentary fixation using open reduction and internal fixation with bioresorbable screws (Mg-Ca alloy, Resomet bioresorbable bone screw; U&I Corp.) and bioresorbable wires (Mg-Ca alloy, Resomet bioresorbable K-wire and pin, U&I Corp.) for displaced comminuted clavicle fractures (Robinson type 2B) and additionally used a metal plate. We expected decreased irritation and infection due to absorption after surgery. We report four cases that were treated in this way.

• Journal of Korean Neurosurgical Society
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• 제45권4호
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• pp.213-218
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• 2009

Objective : This study is a retrospective clinical study over more than 4 years of follow up to understand the mechanism of load sharing across the graft-bone interface in the static locking plate (SLP) fixation compared with non-locking plate (NLP). Methods : Orion locking plates and Top non-locking plates were used for SLP fixation in 29 patients and NLP fixation in 24 patients, respectively. Successful interbody fusion was estimated by dynamic X-ray films. The checking parameters were as follows : screw angle (SA) between upper and lower screw, anterior and posterior height of fusion segment between upper and lower endplate (AH & PH), and upper and lower distance from vertebral endplate to the end of plate (UD & LD). Each follow-up value of AH and PH were compared to initial values. Contributions of upper and lower collapse to whole segment collapse were estimated. Results : Successful intervertebral bone fusion rate was 100% in the SLP group and 92% in the NLP group. The follow-up mean value of SA in SLP group was not significantly changed compared with initial value, but follow-up mean value of SA in NLP group decreased more than those in SLP group (p=0.0067). Statistical analysis did not show a significant difference in the change in AH and PH between SLP and NLP groups (p>0.05). Follow-up AH of NLP group showed more collapse than PH of same group (p=0.04). The upper portion of the vertebral body collapsed more than the lower portion in the SLP fixation (p=0.00058). Conclusion : The fused segments with SLP had successful bone fusion without change in initial screw angle, which was not observed in NLP fixation. It suggests that there was enough load sharing across bone-graft interface in SLP fixation.

• 대한치과보철학회지
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• 제44권2호
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• pp.217-228
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• 2006

Statement of problem: Standard type of ITI solid implant model in the 6.2mm thick jaw bone was axisymmetrically modelled for finite element stress analyses. Purpose: Primary objective was to investigate the influences or the characteristic design configuration of the ITI solid implant model on the bone stress with the course of osseointegration process at the bone/implant interfaces. To simulate the characteristics of the osseointegration process, five different stages of the bone/implant interface model were implemented. As load conditions, vertical load of 50N was taken into consideration. Bone at the cervical region of implant was the areas of concern where the higher level of stress were likely to take place. Results: The results indicated that rather slightly different stress level could be obtained as a function of the osseointegration conditions. Conclusion: Under vertical load, the lower level of stress was observed at the cervical cortical bone in the initial and final stages of osseointegration. Relatively higher stress level, however, was observed during the transitional stages where the osseointegration at the cancellous bone interface were yet to fully develop.

• Journal of Multimedia Information System
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• 제6권2호
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• pp.67-74
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• 2019

Bone density is one of the factors in the early failure of dental implants and doctors should make a preoperative assessment of jaw bone density using patient's CT data before dental implant surgery in order to find out whether the patient has osteoporosis and osteopenia. The main goal of this study was to propose a method that based on image processing techniques in order to provide accurate information about where to drill and place an abutment screw of implants in the jaw bone for doctors and reduce human activity for the estimation of the local cancellous bone density of mandible using CT data. The experiment was performed on a computed tomography data of the jaw bone of two different individuals. We assumed that the result of the estimation of jaw bone density depends on the angle of drilling and average HU (Hounsfield Unit) values were used to evaluate the quality of local cancellous bone density of mandible. As a result of this study, we have been developed a toolbox that can be used to estimate jaw bone density automatically and found a positive correlation between the angle of the drill and time complexity but a negative correlation between the diameter of the drill and time complexity.