• Title/Summary/Keyword: Biomedical materials

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Mechanical Behavior of Porcine Abdominal Organ Tissue with Resuscitative Endovascular Balloon Occlusion of the Aorta (혈관내 풍선 확장에 의한 대동맥 차단소생술이 적용된 돼지 복부 장기 조직의 기계적 거동 평가)

  • Wang, Il Jae;You, Ji-Hun;Huh, Up;Song, Seunghwan;Ahn, Hyo Young;Song, Chan-Hee;Lee, Chi-Seung;Ryu, Dong-Man
    • Korean Journal of Materials Research
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    • v.30 no.4
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    • pp.197-203
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    • 2020
  • Abdominal organs are the most vulnerable body parts under vehicle trauma, and there is high mortality from acute injuries in accidents. There are various ways to reduce this high mortality; one method is Resuscitative Endovascular Balloon Occlusion of the Aorta, which has recently become very popular as a minimally invasive alternative in the emergent management of patients with non-compressible hemorrhages below the diaphragm. However, high safety factor for patients is applied in actual clinical practice because there is no exact standard for the operating time. Therefore, in this study, the effects of the mechanical behavior of organ tissues for the duodenum, kidney, and liver on the operating time of Resuscitative Endovascular Balloon Occlusion of the Aorta is investigated in order to obtain data needed to establish standards of operating time. In characteristic analysis of organ tissues, uniaxial tensile test and compression test are conducted according to the operating time.

Research Trends of Cathode Materials for Lithium-Ion Batteries used in Electric Vehicles (전기자동차용 리튬이온전지를 위한 양극전극 분말 재료의 연구 동향)

  • Shin, Dong-Yo;Ahn, Hyo-Jin
    • Journal of Powder Materials
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    • v.26 no.1
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    • pp.58-69
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    • 2019
  • High performance lithium-ion batteries (LIBs) have attracted considerable attention as essential energy sources for high-technology electrical devices such as electrical vehicles, unmanned drones, uninterruptible power supply, and artificial intelligence robots because of their high energy density (150-250 Wh/kg), long lifetime (> 500 cycles), low toxicity, and low memory effects. Of the high-performance LIB components, cathode materials have a significant effect on the capacity, lifetime, energy density, power density, and operating conditions of high-performance LIBs. This is because cathode materials have limitations with respect to a lower specific capacity and cycling stability as compared to anode materials. In addition, cathode materials present difficulties when used with LIBs in electric vehicles because of their poor rate performance. Therefore, this study summarizes the structural and electrochemical properties of cathode materials for LIBs used in electric vehicles. In addition, we consider unique strategies to improve their structural and electrochemical properties.

Cellulose Nanocrystals as Advanced "Green" Materials for Biological and Biomedical Engineering

  • Sinha, Arvind;Martin, Elizabeth M.;Lim, Ki-Taek;Carrier, Danielle Julie;Han, Haewook;Zharov, Vladimir P.;Kim, Jin-Woo
    • Journal of Biosystems Engineering
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    • v.40 no.4
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    • pp.373-393
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    • 2015
  • Background: Cellulose is a ubiquitous, renewable and environmentally friendly biopolymer, which has high promise to fulfil the rising demand for sustainable and biocompatible materials. Particularly, the recent progress in the synthesis of highly crystalline cellulose-based nanoscale biomaterials, namely cellulose nanocrystals (CNCs), draws significant attention from many research communities, ranging from bioresource engineering, to materials science and engineering, to biological and biomedical engineering to bionanotechnology. The feasibility of harnessing CNCs' unique biophysicochemical properties has inspired their basic and applied research, offering much promise for new biomaterials with diverse advanced functionalities. Purpose: This review focuses on vital issues and topics on the recent advances in CNC-based biomaterials with potential, in particular, for bionanotechnology and biological and biomedical engineering. The challenges and limitations of CNC technology are discussed as well as potential strategies to overcome them, providing an essential source of information in the exploration of possible and futuristic applications of the CNC-based functional "green" nanomaterials. Conclusion: CNCs offer exciting possibilities for advanced "green" nanomaterials, driving innovative research and development in a wide range of fields, including biological and biomedical engineering.

Research Status and Prospectives of Magnetic Nanoparticles in Bio-medical Applications (바이오-메디컬 자성나노입자 연구의 현황과 전망)

  • Min, J.H.;Song, A.Y.;Kim, Y.K.;Wu, J.H.
    • Journal of the Korean Magnetics Society
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    • v.19 no.1
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    • pp.28-34
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    • 2009
  • Magnetic nanoparticles are widely used for bio-medical applications such as MRI contrast agents, drug-delivery systems, cell separation and hyperthermia, thanks to their unique magnetic properties and physico-chemical characteristics. In the early stage, efforts were focused on synthesis of uniform nanoparticles of desired dimension to achieve targeted, stable functionalities. Recently, it has been of great interest in dispersion of such nanoparitcles in aqueous solution and to render the nanoparticles bio-compatible with biofunctionality on request for utilization in bio-medical fields. In this paper, we survey the research status and give prospective on future work of magnetic nanoparticles for biomedical applications.

Biomedical Applications of Silk Protein

  • Kweon, Hae-Yong;Cho, Chong-Su
    • International Journal of Industrial Entomology and Biomaterials
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    • v.3 no.1
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    • pp.1-6
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    • 2001
  • Silk protein has been investigated by many researchers to apply to biomedical field. We reviewed biomedical applications of silk protein such as matrix of wound dressing and drug delivery system. Since silk fibroin/ poly (ethylene glycol) (PEG) semi-interpenetrating polymer networks showed good mechanical properties and wound healing phenomena, it can be used as wound dressing materials. Sericin nanoparticles pre- pared by conjugation with PEG and silk protein/ poloxamer mixture gel are expected to become a deliv- ery as matrix for hydrophobic drug.

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Thermal Comfort Condition of Temperature and Humidity in Loess Interior Space

  • Kong, Sung-Hoon
    • Biomedical Science Letters
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    • v.10 no.2
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    • pp.129-135
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    • 2004
  • The study was carried out through measuring the temperature and humidity of the indoor/outdoor space and the distribution of interior thermal condition, and investigating the effect of loess materials on human body. The purpose of this study is to analyze the change of dry bulb temperature and relative humidity and correlation of thermal reaction of human body with ASHRAE (American Society of Heating, Refrigerating and Air-conditioning) comfort chart in the loess interior space. In the view point of biomedical sciences, loess interior space provides optimum thermal conditions for human thermal sensation.

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A Study on the X-Ray Imaging using Dusl Energy Method (이중에너지 방법을 이용한 X선 영상법에 관한 연구)

  • 신동익;김종효
    • Journal of Biomedical Engineering Research
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    • v.9 no.2
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    • pp.185-194
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    • 1988
  • The dual-energy technique win used to separate the bone-only and tissue-only images from the conventional chest images. The equivalent thickness of the basic materials are estimated from low and high energy images of a given complex materials using the attenuation coefficient of ma serial componens. We showed that the image quality of dual-energy imaging method can be influenced by the ponlinearity and noise components of system and spectrum distributions The quantitative analysis of Calcium component was performed by dual-energy technique and it is shown that the concentration of the Calcium could be accurately estimated within 5% error range.

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The Expression of Corazonin Neurons in Larvae Stage of Scuttle Fly

  • Park, Hohyun
    • Biomedical Science Letters
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    • v.26 no.3
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    • pp.217-225
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    • 2020
  • Scuttle fly which moves abruptly after standing for a while and stop suddenly to rush off again, is a fly species in the Phoridae family. This species like rotten organic materials and it is known to proliferate even in the industrial materials including organic solvents. These characteristic behaviors of the scuttle fly seem to be related to muscular and nervous system or neurotransmitters. Thus, we focused at the neurotransmitter, corazonin (Crz) that is known to be related to resistance to stress and investigated the developmental process of the neurons in the scuttle fly. Corazonin is a neuropeptide being expressed in the central nervous system (CNS) and is known to control mainly physiological functions and behaviors. Its many functions that have been proposed are still in controversy. In this studies, we found that there are three groups of corazoninergic neurons in the larval CNS of the scuttle fly and these neurons undergo distinguishable changes through metamorphic process compared to different fly species. Larva has 3 pairs of Crz neurons at the dorsolateral area of the brain, 1 pair at the dorsomedial brain and 8 pairs at the ventral nerve cord.

Effect of High Pressure and Steaming Extraction Processes on Ginsenosides Rg3 and Rh2 Contents of Cultured-Root in Wild Ginseng (Panax ginseng C. A. Meyer) (초고압 증숙처리가 산삼배양근의 진세노사이드 Rg3와 Rh2의 함량에 미치는 영향)

  • Choi, Woon-Yong;Lee, Choon-Geun;Seo, Yong-Chang;Song, Chi-Ho;Lim, Hye-Won;Lee, Hyeon-Yong
    • Korean Journal of Medicinal Crop Science
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    • v.20 no.4
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    • pp.270-276
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    • 2012
  • This study was performed to enhance contents of low molecular weight ginsenoside Rh2 and Rg3 using an ultra high pressure and steaming process in wild cultured-Root in wild ginseng. For selective increase in contents of Rg3 and Rh2 in cultured wild ginseng roots, an ultra high extraction was applied at 500MPa for 20 min which was followed by steaming process at $90^{\circ}C$ for 12 hr. It was revealed that contents of ginsenosides, Rb1, Rb2, Rc and Rd, were decreased with the complex process described above, whereas contents of ginsenoside Rh2 and Rg3 were increased up to 4.918 mg/g and 6.115 mg/g, respectively. In addition, concentration of benzo[${\alpha}$]pyrene in extracts of the cultured wild ginseng roots treated by the complex process was 0.64 ppm but it was 0.78 ppm when it was treated with the steaming process. From the results, it was strongly suggested that low molecular weight ginsenosides, Rh2 and Rg3, are converted from Rb1, Rb2, Rc, and Rd which are easily broken down by an ultra high pressure and steaming process. This results indicate that an ultra high pressure and steaming process can selectively increase in contents of Rg3 and Rh2 in cultured wild ginseng roots and this process might enhance the utilization and values of cultured wild ginseng roots.