• 대한수학회논문집
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• 제25권3호
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• pp.457-475
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• 2010

In this paper, we have use a fuzzy bitopological space (X, $\tau_1$, $\tau_2$) to create a family $\tau_{ij}^s$ which is a supra fuzzy topology on X. Also, we introduce and study the concepts of r-($\tau_i$, $\tau_j$)-generalized fuzzy regular closed, r-($\tau_i$, $\tau_j$)-generalized fuzzy strongly semi-closed and r-($\tau_i$, $\tau_j$)-generalized fuzzy regular strongly semi-closed sets in fuzzy bitopological space in the sense of $\check{S}$ostak. Also, these classes of fuzzy subsets are applied for constructing several type of fuzzy closed mapping and some type of fuzzy separation axioms called fuzzy binormal, fuzzy mildly binormal and fuzzy almost pairwise normal.

• The Korean Journal of Pain
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• 제32권4호
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• pp.256-263
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• 2019

Background: Antinociceptive anti-inflammatory drugs have many adverse effects. The goal of this investigation is to study the probable anti-inflammatory and analgesic effects of verapamil and N-acetylcysteine (NAC) in experimental rats. Methods: Adult male Wistar rats were randomly divided into 4 groups in the antinociceptive study, each containing 6 rats; the normal control group, which received saline (1 mL/kg); the diclofenac group, which received diclofenac sodium (5 mg/kg); the NAC group, which received NAC (125 mg/kg); and the verapamil group, which received verapamil (8 mg/kg). In the anti-inflammatory study, 5 groups were used, the 4 previous groups with the addition of an edema control group, received saline and were subjected to formalin test. Hot plate latency time was recorded for antinociceptive evaluation. Paw edema thickness and biochemical parameters were recorded for anti-inflammatory evaluation. Results: Administration of NAC showed significant prolongation of hot plate latency time at 1 hour when compared to the control group while verapamil showed a significant prolongation of hot plate latency time at 1 and 2 hours when compared to the control group and NAC group values. Administration of NAC and verapamil significantly decreased paw edema thickness at 2, 4, and 8 hours when compared to edema control values. Regarding biochemical markers, NAC and verapamil significantly decreased serum nitric oxide synthase, C-reactive protein, and cyclooxygenase-2 levels compared to the edema control value. In accordance, a marked improvement of histopathological findings was observed with both drugs. Conclusions: NAC and verapamil have antinociceptive and anti-inflammatory effects comparable to diclofenac sodium.

• 한국지능시스템학회논문지
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• 제12권2호
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• pp.187-191
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• 2002

In this paper, we introduce the notion of smooth neighborhoods in smooth topological spaces and investigate some of their properties. In particular, we can obtain some smooth topologies from a smooth neighborhood system.

• 대한수학회보
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• 제45권2호
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• pp.207-220
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• 2008

We introduce and study the notions of supra fuzzy convergence of fuzzy filters, $s{\gamma}$-fuzzy open (closed) sets, $s{\gamma}(/TEX>$s{\gamma}^*)$-fuzzy continuous and $s{\gamma}$-fuzzy open mapping. Also. we investigate some of fundamental properties of these notions.

• International Journal of Fuzzy Logic and Intelligent Systems
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• 제2권1호
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• pp.83-88
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• 2002

We study some properties of smooth uniform spaces. We investigate the relationship between smooth topological spaces and smooth uniform spaces. In particular, we define a subspace of a smooth uniform space and a product of smooth uniform spaces.

• 대한수학회지
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• 제54권6호
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• pp.1787-1799
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• 2017

In this paper, we prove basic a priori estimate for the ${\bar{\partial}}$-Neumann problem on an annulus between two pseudoconvex submanifolds of a Stein manifold. As a corollary of the result, we obtain the global regularity for the ${\bar{\partial}}$-problem on the annulus. This is a manifold version of the previous results on pseudoconvex domains.

• Journal of applied mathematics & informatics
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• 제40권5_6호
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• pp.1105-1115
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• 2022

The main objective of this paper is to introduce the notion of AMR-algebra and its generalization, and to compare them with other algebras such as BCK, BCI, BCH, · · ·, etc. We show moreover that the K-part of AMR-algebra is an abelian group, and the weak AMR-algebra is also an abelian group and generalizes many known algebras like BCI, BCH, and G.

• Journal of Microbiology and Biotechnology
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• 제30권8호
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• pp.1156-1168
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• 2020

Drought stress is threatening the growth and productivity of many economical crops. Therefore, it is necessary to establish innovative and efficient approaches for improving crop growth and productivity. Here we investigated the potentials of the cell-free extract of Actinobacteria (Ac) isolated from a semi-arid habitat (Al-Jouf region, Saudi Arabia) to recover the reduction in maize growth and improve the physiological stress tolerance induced by drought. Three Ac isolates were screened for production of secondary metabolites, antioxidant and antimicrobial activities. The isolate Ac3 revealed the highest levels of flavonoids, antioxidant and antimicrobial activities in addition to having abilities to produce siderophores and phytohormones. Based on seed germination experiment, the selected bioactive fraction of Ac3 cell-free extract (F2.7, containing mainly isoquercetin), increased the growth and photosynthesis rate under drought stress. Moreover, F2.7 application significantly alleviated drought stress-induced increases in H₂O₂, lipid peroxidation (MDA) and protein oxidation (protein carbonyls). It also increased total antioxidant power and molecular antioxidant levels (total ascorbate, glutathione and tocopherols). F2.7 improved the primary metabolism of stressed maize plants; for example, it increased in several individuals of soluble carbohydrates, organic acids, amino acids, and fatty acids. Interestingly, to reduce stress impact, F2.7 accumulated some compatible solutes including total soluble sugars, sucrose and proline. Hence, this comprehensive assessment recommends the potentials of actinobacterial cell-free extract as an alternative ecofriendly approach to improve crop growth and quality under water deficit conditions.

• Clinical and Experimental Pediatrics
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• 제62권8호
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• pp.307-311
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• 2019

Purpose: Necrotizing enterocolitis (NEC) is one of the most serious complications of prematurity. Many risk factors can contribute to the development of NEC. The epidermal growth factor (EGF) plays a major role in intestinal barrier function, increases intestinal enzyme activity, and improves nutrient transport. The aim of this study was to assess the role of epidermal growth factor in the development of NEC in preterm neonates. Methods: In this study, 130 preterm neonates were included and divided into 3 groups, as follows: group 1, 40 preterm neonates with NEC; group 2, 50 preterm neonates with sepsis; and group 3, 40 healthy preterm neonates as controls. The NEC group was then subdivided into medical and surgical NEC subgroups. The serum EGF level was measured using enzyme-linked immunosorbent assay. Results: Serum EGF levels (pg/dL) were significantly lower in the NEC group (median [interquartile range, IQR], 9.6 [2-14]) than in the sepsis (10.1 [8-14]) and control groups (11.2 [8-14], P<0.001), with no significant difference between the sepsis and control groups, and were positively correlated with gestational age (r=0.7, P<0.001). A binary logistic regression test revealed that low EGF levels and gestational ages could significantly predict the development of NEC. The receiver-operating characteristic curve for EGF showed an optimal cutoff value of 8 pg/mL, with 73.3% sensitivity, 98% specificity, and an area under the curve of 0.92. Conclusion: The patients with NEC in this study had significantly lower serum EGF levels (P<0.001), which indicated that EGF could be a reliable marker of NEC in preterm neonates.

• 대한수학회논문집
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• 제33권2호
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• pp.409-421
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• 2018

Let X be a complex manifold of dimension n $n{\geqslant}2$ and let ${\Omega}{\Subset}X$ be a weakly q-convex domain with smooth boundary. Assume that E is a holomorphic line bundle over X and $E^{{\otimes}m}$ is the m-times tensor product of E for positive integer m. If there exists a strongly plurisubharmonic function on a neighborhood of $b{\Omega}$, then we solve the ${\bar{\partial}}$-problem with support condition in ${\Omega}$ for forms of type (r, s), $s{\geqslant}q$ with values in $E^{{\otimes}m}$. Moreover, the solvability of the ${\bar{\partial}}_b$-problem on boundaries of weakly q-convex domains with smooth boundary in $K{\ddot{a}}hler$ manifolds are given. Furthermore, we shall establish an extension theorem for the ${\bar{\partial}}_b$-closed forms.