• Human Ecology Research
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• 제60권2호
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• pp.177-186
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• 2022

The purpose of this study was to explore the relationships among mothers' reflective function, preschoolers' empathy, executive function, caring behaviors. Subjects for this study were 498 preschoolers and their mothers. Mothers' reflective function was assessed by the Parental Reflective Functioning Questionnaire(PRFQ). Preschoolers' empathy was assessed by the Questionnaire of Cognitive and Affective Empathy(QCAE). Preschoolers' executive function was assessed by the Behavioral Rating Inventory of Executive Functions-Preschool Version(BRIEF-P), and caring behaviors were assessed by the caring behaviors scale(Kim, 2015). Data were analyzed using descriptive statistics, confirmatory factor analysis(CFA), and structural equation model(SEM) with the SPSS 25.0 and AMOS 23.0 program. The major results of this study were as follows. First, mothers' reflective function showed direct effects on preschoolers' empathy, executive function, and caring behaviors. Second, the preschoolers' empathy and executive function showed direct effects on preschoolers' caring behaviors. Third, preschoolers' empathy mediated the effects of mothers' reflective function on preschoolers' caring behaviors. The findings of this study will contribute to designing intervention programs to improve preschoolers' empathy, executive function, and caring behaviors.

• 한국통신학회논문지
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• 제32권5B호
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• pp.286-294
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• 2007

ASIP 디자인에서 디자인되는 프로세서의 성능을 측정할 수 있는 컴파일러가 요구된다. 머쉰에 맞는 컴파일러 설계는 매우 많은 시간을 요구한다. 본 논문은 MDL 기술로부터 C 컴파일러를 생성하는 시스템을 보인다. MDL을 이용한 컴파일러 생성은 user retargetability와 컴파일러와 프로세서 디자인의 일관성을 유지시켜 준다. 그러나 MDL을 이용한 컴파일러 생성 시스템은 컴파일러와 머쉰 간 의미적 차이를 줄여야 한다. 이러한 문제를 해결하기 위해 제안하는 시스템은 트리 패턴마다 행위정보를 가지는 라이브러리에 머쉰 행위기술을 맵핑한다. 맵핑된 인스트럭션과 레지스터 파일 사용정보를 이용해 제안하는 시스템은 컴파일러 후위부 interface function을 생성한다. 생성된 MIPS R3000와 ARM9 컴파일러가 C로 기술된 어플리케이션 프로그램으로 검증되었다.

• Journal of Ginseng Research
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• 제48권1호
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• pp.59-67
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• 2024

Background: Alzheimer's disease (AD) has memory impairment associated with aggregation of amyloid plaques and neurofibrillary tangles in the brain. Although anti-amyloid β (Aβ) protein antibody and chemical drugs can be prescribed in the clinic, they show adverse effects or low effectiveness. Therefore, the development of a new drug is necessarily needed. We focused on the cognitive function of Panax ginseng and tried to find active ingredient(s). We isolated panaxcerol D, a kind of glycosyl glyceride, from the non-saponin fraction of P. ginseng extract. Methods: We explored effects of acute or sub-chronic administration of panaxcerol D on cognitive function in scopolamine- or Aβ_25-35 peptide-treated mice measured by several behavioral tests. After behavioral tests, we tried to unveil the underlying mechanism of panaxcerol D on its cognitive function by Western blotting. Results: We found that pananxcerol D reversed short-term, long-term and object recognition memory impairments. The decreased extracellular signal-regulated kinases (ERK) or Ca²⁺/calmodulin-dependent protein kinase II (CaMKII) in scopolamine-treated mice was normalized by acute administration of panaxcerol D. Glial fibrillary acidic protein (GFAP), caspase 3, NF-kB p65, synaptophysin and brainderived neurotrophic factor (BDNF) expression levels in Aβ_25-35 peptide-treated mice were modulated by sub-chronic administration of panaxcerol D. Conclusion: Pananxcerol D could improve memory impairments caused by cholinergic blockade or Aβ accumulation through increased phosphorylation level of ERK or its anti-inflammatory effect. Thus, panaxcerol D as one of non-saponin compounds could be used as an active ingredient of P. ginseng for improving cognitive function.

• 중환자간호학회지
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• 제14권1호
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• pp.50-62
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• 2021

Purpose : This study examined the effects of an integrated management program on physical function, cognitive function, and depression in patients with subacute stroke. Methods : A nonequivalent control group design was adopted. The participants were assigned to either the experimental group (n=20) or control group (n=23). The experimental group received an 8-week integrated management program and standard rehabilitation service (i.e., physical therapy and occupational therapy), while the control group received the standard rehabilitation service only. Physical function was measured as gait speed and balance ability using the Berg Balance Scale (BBS). Cognitive function was measured with neuro-behavioral cognitive status examination (NCSE), and depression was measured using the Beck Depression Inventory-II (BDI-II). Repeated measure ANOVA was used to determine changes in physical function, cognitive function, and depression over 8-weeks. Results : The interaction between group and time was significant, indicating that the experimental group showed improvement in gait speed, balance ability, cognitive function (linguistic ability, linguistic memory, reasoning), and a decrease in depression compared to the control group. Conclusion : These results indicate that the integrated management program developed herein was beneficial in restoring physical function, cognitive function, and depression in subacute stroke patients.

• Nuclear Medicine and Molecular Imaging
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• 제40권1호
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• pp.1-8
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• 2006

Addiction to illicit drugs is one of today's most important social issues. Most addictive drugs lead to irreversible parenchymal changes in the human brain. Neuroimaging data bring to light the pharmacodynamics and pharmacokinetics of the abused drugs, and demonstrate that addiction is a disease of the brain. Continuous researches better illustrate the neurochemical alterations in brain function, and attempt to discover the links to consequent behavioral changes. Newer hypotheses and theories follow the numerous results, and more rational methods of approaching therapy are being developed. Substance abuse is on the rise in Korea, and social interest in the matter as well. On the other hand, diagnosis and treatment of drug addiction is still very difficult, because how the abused substance acts in the brain, or how it leads to behavioral problems is not widely known. Therefore, understanding the mechanism of drug addiction can improve the process of diagnosing addict patients, planning therapy, and predicting the prognosis. Neuroimaging approaches by nuclear medicine methods are expected to objectively judge behavioral and neurochemical changes, and response to treatment. In audition, as genes associated with addictive behavior are discovered, functional nuclear medicine images will aid in the assessment of individuals. Reviewing published literature on neuroimaging regarding nuclear medicine is expected to be of assistance to the management of drug addict patients. What's more, means of applying nuclear medicine to the care of drug addict patients should be investigated further.

• 한국사회복지학
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• 제40권
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• pp.5-37
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• 2000

The purpose of this study is to find out some characteristics of the family functions of single mothers to provide some useful data for the development of programs which may help single mothers to improve their family functions. The McMaster Family Assessment Device (FAD) which is composed of problem solving function (PS), communication function (CF), role function (RC), emotional reaction function (ER), emotional involvement (EI), behavioral control function (BC), and general function (GC) and McCubbins' FSI were administered to single mothers and their adolescent children and mothers and their adolescent children of ordinary families (control family). The single mothers' perception of their family function was lower than that of control family mothers in an the 7 categories of FAD. The perceptions of the family function of the single mothers' children were lower than those of control family mothers' children. There was on significant difference between the perceptions of single mothers and their children in PS, ER, EI, GC of their family. However, single mothers' perception in RC and BC was lower than that of their children, and the children's perception in CF were lower than that of their mothers. Single mothers who fall on the period of single motherhood was shorter than 7 years perceived their families' function as lower than that of single mothers' who fall on the periods of single motherhood longer than 7 years in all categories. Generally speaking, the single mothers' family functions were lower than that of control family. The different characteristics of each single mother's family functions should be considered in developing programs for single mothers.

• 대한감각통합치료학회지
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• 제15권2호
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• pp.35-45
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• 2017

목적 : 본 연구는 주의력결핍과잉행동장애(Attention-Deficit/Hyperactivity Disorder; ADHD) 아동에게 사용되는 상호작용식 메트로놈(Interactive Metronome; IM) 프로토콜을 기반으로 임상에 적용 가능하도록 수정된 IM 프로그램이 ADHD 아동의 행동증상, 타이밍 및 운동기능에 미치는 효과를 알아보고자 한다. 연구방법 : 본 연구는 부산 소재의 기초정신건강증진센터 내에 있는 7-12세의 ADHD 아동 13명을 대상으로 단일 집단 사전-사후 설계(one group pretest-posttest design)를 사용하였다. 중재는 회당 30분, 주 3회, 24회기 동안 실시하였으며, 중재 전과 후의 행동증상, 타이밍 및 운동기능 변화를 비교하기 위해 부모보고형 한국어판 ADHD 평정척도, IM의 Long Form Assessment(LFA), Bruininks-Oseretsky Test of Motor Proficiency 2판(BOT-2)을 사용하였다. 결과 : 행동증상 중 과잉행동/충동성에서 유의미한 향상이 있었고, 타이밍과 손의 협응 및 신체협응에서 통계적으로 유의미한 향상이 있었다. 결론 : 임상에 적용 가능하도록 수정된 IM 프로그램이 ADHD 아동의 행동증상을 개선하고, 타이밍 및 운동기능 향상에 유의한 효과가 있다.

• 정신신체의학
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• 제26권2호
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• pp.119-126
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• 2018

연구목적 본 연구의 목적은 알츠하이머병 및 경도인지장애 환자에서 백질고강도신호 차이에 따른 신경인지 기능 및 행동심리증상(BPSD)을 비교하는 것이다. 방 법 본 연구는 후향적 연구로서, 알츠하이머병 및 경도인지장애로 진단받은 115명을 대상으로 하였다. 뇌 자기공명영상의 백질 고강도 신호(white matter hyperintensity, WMH)는 표준화된 시각 기반 척도(Fazekas scales)에 의해 평가되었으며, 참가자들은 Fazekas 척도에 따라 두 그룹으로 분류되었다. 신경인지기능은 임상치매평가척도(CERAD-K)에 의해, BPSD는 한국형 신경정신행동검사(K-NPI)로 평가되었다. WMH의 심각도에 따른 신경인지기능 및 BPSD의 차이를 분석하기 위해 독립표본 t-test를 시행하였다. 결 과 WMH의 중증도가 높은 군은 유의하게 낮은 언어 유창성을 나타내었다(p<0.05). 또한 WMH의 중증도가 높은 군은 유의하게 높은 K-NPI 점수를 보였다(p<0.01). 결 론 WMH와 실행기능과 관련된 신경인지검사 간에는 유의한 연관이 있었다. 또한 WMH는 BPSD의 중증도에 영향을 미치는 것으로 보인다. 임상실제에서 WMH를 알츠하이머 병(Alzheimer's disease, AD)및 경도인지장애(Mild cognitive impairment, MCI)환자를 치료하는데 유용한 정보를 제공할 것이다.

• 국제물리치료학회지
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• 제5권1호
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• pp.691-695
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• 2014

The purpose of this study was to determine the effects of swiss ball program training on lower extremity function of old elderly with mild cognitive impairment. The subjects were 30 mild cognitive impairment eldrly people aged between 65 and 80, who were divided into the swiss ball program training group(n=15) and the control group(n=15). The swiss ball program training group engaged in a 50-minute exercise session using. Lower extremity function scale of the two groups were measured before and after the intervention. The results are as follows. According to the swiss ball program training conducted to examine the effects of the training on lower extremity function, Moreover, the two groups showed significant differences in lower extremity function. These results indicate that virtual reality training is effective in improving lower extremity function. To conclusion, swiss ball program was found to have a positive effect on elderly lower extremity function. Swiss ball program training can be proposed as a form of fall prevention exercise for the mild cognitive impairment. Swiss ball program may be helpful to reduce the incidence of dementia and behavioral complications.

• 한국물환경학회지
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• 제27권5호
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• pp.661-669
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• 2011

The purpose of this study is quantitative analysis of the effects of the interactions between stream network and hillslope to hydrologic response functions. To this end general formulation of hydrologic response function is performed based on width function and grid framework. Target basins are Ipyeong and Tanbu basins. From the results of width function estimation even similar sized and closely located basins could have very different hydrologic response function. It is found out that the interactions between stream network and hillslope are essential factors of rainfall-runoff processes because their difference can make the hydrologic response function with positive skewness. The change of velocities of stream network and hillslope might influence the magnitude of peak but time to peak tends to more sensitively respond to velocities of stream network. Lag time of basin would be the result of complex interaction between drainage structures and dynamic properties of river basin.