• The Korean Journal of Mycology
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• v.49 no.2
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• pp.243-248
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• 2021

In this study, screening of potent non-pathogenic wild yeast with high anti-dementia butyrylcholinesterase (BChE) inhibitory activity and production condition of a BChE inhibitor were described. Among 36 non-pathogenic wild yeasts, Saccharomyces cerevisiae WJSL 0113 showed the highest BChE inhibitory activity of 85.2%. The specific BChE inhibitor was maximally produced when S. cerevisiae WJSL 0113 was cultured at 30℃ for 48 h in a yeast extract-peptone-dextrose medium.

• Journal of Sensor Science and Technology
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• v.24 no.3
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• pp.188-193
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• 2015

This paper presents a new byte-wise BCH (4122, 4096, 2) decoder, which treats byte-wise parallel operations so as to enhance its throughput. In particular, we evaluate the parallel processing technique for the most time-consuming components such as syndrome generator and Chien search owing to the iterative operations. Even though a syndrome generator is based on the conventional LFSR architecture, it allows eight consecutive bit inputs in parallel and it treats them in a cycle. Thus, it can reduce the number of cycles that are needed. In addition, a Chien search eliminates the redundant operations to reduce the hardware complexity. The proposed BCH decoder is implemented with VHDL and it is verified using a Xilinx FPGA. From the simulation results, the proposed BCH decoder can enhance the throughput as 43% and it can reduce the hardware complexity as 67% compared to its counterpart employing parallel processing architecture.

• Proceedings of the Korean Institute of Information and Commucation Sciences Conference
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• 2009.05a
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• pp.485-488
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• 2009

The class of BCH codes is a large class of error correction codes. HDL implementation of BCH code generator to change code rate. and used System Generator, and implemented hardware to FPGA. Loaded bit stream to a FPGA board in order to verify this design to Hardware co-simulation from these results. Also, compared as investigated the maximum action frequency through timing analysis and resource of logic in order to evaluate performance of BCH code generator.

• Journal of Microbiology and Biotechnology
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• v.26 no.5
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• pp.959-966
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• 2016

Chlorophyll synthase (ChlG) and bacteriochlorophyll synthase (BchG) have a high degree of substrate specificity. The BchG mutant of Rhodobacter sphaeroides, BG1 strain, is photosynthetically incompetent. When BG1 harboring chlG of Synechocystis sp. PCC 6803 was cultured photoheterotrophically, colonies arose at a frequency of approximately 10^-8. All the suppressor mutants were determined to have the same mutational change, ChlG_I44F. The mutated enzyme ChlG_I44F showed BchG activity. Remarkably, BchG_F28I, which has the substitution of F at the corresponding 28^th residue to I, showed ChlG activity. The K_m values of ChlG_I44F and BchG_F28I for their original substrates, chlorophyllide (Chlide) a and bacteriochlorophyllide (Bchlide) a, respectively, were not affected by the mutations, but the K_m values of ChlG_I44F and BchG_F28I for the new substrates Bchlide a and Chlide a, respectively, were more than 10-fold larger than those for their original substrates, suggesting the lower affinities for new substrates. Taken together, I44 and F28 are important for the substrate specificities of ChlG and BchG, respectively. The BchG activity of ChlG_I44F and the ChlG activity of BchG_F28I further suggest that ChlG and BchG are evolutionarily related enzymes.

• Journal of Genetic Medicine
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• v.3 no.1
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• pp.29-32
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• 1999

The Apolipoprotein E type 4 allele (ApoE ${\varepsilon}4$) is genetically associated with the common late onset familial and sporadic forms of Alzheimer's disease. The BchE-k variant, which is the common variant of the BchE gene, has been reported to show allelic association with AD in subjects who are also carriers of the ${\varepsilon}4$ allele of the ApoE, especially in subjects over the age of 75. This study was performed to evaluate the distribution of the ApoE and the BchE genotypes in the healthy and AD groups and to evaluate the synergy between the BchE-k variant and the ApoE ${\varepsilon}4$ in AD. The ApoE and the BchE genotypes were determined in DNA samples from 610 healthy people and 60 LOAD patients by using ARMS by standard agarose gel electrophoresis. The effect of the ApoE ${\varepsilon}4$ was closely related to AD(p<0.05). A comparison between the AD patients and the healthy individuals, both with the ${\varepsilon}4$ allele, indicated an interaction between the BchE-k and the ApoE ${\varepsilon}4$(p<0.05). The association of the BchE-k with AD was limited to carriers of the ApoE ${\varepsilon}4$ allele, among whom the presence of the BchE-k gave an odds ratio of AD 3.48 (95% C.I. 1.3-9.2). Therefore, these results suggested that further evidence of an association between the ApoE ${\varepsilon}4$ and LOAD, and the BchE-k acts in synergy with the ApoE ${\varepsilon}4$ as a susceptibility gene for AD.

• International Journal of Contents
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• v.9 no.1
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• pp.33-37
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• 2013

BCH code is one of the most widely used error correcting code for the detection and correction of random errors in the modern digital communication systems. The conventional BCH encoder that is operated in bit-serial manner cannot adequate with the recent high speed appliances. Therefore, parallel encoding algorithms are always a necessity. In this paper, we introduced a new systolic array type BCH parallel encoder. To study the area and speed, several parallel factors of the systolic array encoder is compared. Furthermore, to prove the efficiency of the proposed algorithm using tree-type structure, the throughput and the area overhead was compared with its counterparts also. The proposed BCH encoder has a great flexibility in parallelization and the speed was increased by 40% than the original one. The results were implemented on synthesis and simulation on FPGA using VHDL.

• JSTS:Journal of Semiconductor Technology and Science
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• v.13 no.5
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• pp.465-472
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• 2013

This paper presents a low-complexity triple-error-correcting parallel Bose-Chaudhuri-Hocquenghem (BCH) decoder architecture and its efficient design techniques. A novel modified step-by-step (m-SBS) decoding algorithm, which significantly reduces computational complexity, is proposed for the parallel BCH decoder. In addition, a determinant calculator and a error locator are proposed to reduce hardware complexity. Specifically, a sharing syndrome factor calculator and a self-error detection scheme are proposed. The multi-channel multi-parallel BCH decoder using the proposed m-SBS algorithm and design techniques have considerably less hardware complexity and latency than those using a conventional algorithms. For a 16-channel 4-parallel (1020, 990) BCH decoder over GF($2^{12}$), the proposed design can lead to a reduction in complexity of at least 23 % compared to conventional architecttures.

• The Journal of Korean Institute of Communications and Information Sciences
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• v.14 no.4
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• pp.374-387
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• 1989

The decoding method of Binary BCH Codes using symmetric matrix is proposed in this paper. With this method, the error-locator-polynomial is composed by symmetric matrix which consists of the powers of the unknown X plus the synfromes as its elements. The symmetric matirx can also be represented in terms of the unknown X. But the each coefficients of the error-locator polynomial represents the matirx with the syndromes as its entries. By utilizing this proposed algorithm, the device for decoding circuit of the (63, 45) BCH Code for t=3 has been implemented for demonstration.

• Journal of the Institute of Electronics and Information Engineers
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• v.50 no.7
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• pp.140-148
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• 2013

This paper presents a iterative Bose-Chaudhuri-hocquenghem (i-BCH) code and its high-speed decoder architecture for 100 Gb/s optical communications. The proposed architecture features a very high data processing rate as well as excellent error correction capability. The proposed 6-iteration i-BCH code structure with interleaving method allows the decoder to achieve 9.34 dB net coding gain performance at $10^{-15}$ decoder output bit error rate to compensate for serious transmission quality degradation. The proposed high-speed i-BCH decoder architecture is synthesized using a 90-nm CMOS technology. It can operate at a clock frequency of 430 MHz and achieve a data processing rate of 100 Gb/s. Thus, it has potential applications in next generation forward error correction (FEC) schemes for 100 Gb/s optical communications.

• Fisheries and Aquatic Sciences
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• v.2 no.2
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• pp.167-171
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• 1999

This study was designed to develop biomarkers of coastal pollution using biochemical indices of flounder (Paralichthys olivaceus) by changes in lactate dehydrogenase (LDH) activity in the serum and cholinesterase activities in brain membranes. For this purpose acetylcholiesterase (AChE) activity, butyrylcholinesterase (BChE) activity, LDH/AChE ratio and LDH/BChE ratio of cultured flounders at 5 different sites on the southern coast of Korea were compared to those of wild flounders caught in the Pohang, eastern coast of Korea as a control group. Relatively high LDH activities were measured in the serum of flounders cultured on the southern coast of Korea (0.101-0.145 unit) than those in the Pohang control group (0.093 unit). AChE activities were significantly low $(about\;10-20\%)$ in brain membranes of cultured flounders compared to those in the Pohang control group. The ratios of LDH/AChE and LDH/BChE were consistently higher $(136-178\%,\; 155-214\%)$ in cultured flounders than those of Pohang control group. Thus, we propose that the ratios of LDH/AChE and LDH/BChE in flounders could be applicable for the diagnosis of marine pollution.