• Journal of Food Hygiene and Safety
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• v.30 no.2
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• pp.143-149
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• 2015

This study was conducted to simultaneous analysis methods for water soluble vitamins B group (vitamin $B_1$, vitamin $B_2$, nicotinic acid, nicotinamide, vitamin $B_6$) which is used as health functional foods etc. Analytical methods of water-soluble vitamins B group by HPLC were established through instrumental analytical conditions, and the examination of data such as domestic and foreign reliable methods, and papers of journal. HPLC method analyzing water soluble vitamins B group was established using Capcell Pak C18 UG 120 column in 270 nm through test of columns. The validation has been performed on the method to determine linearity, accuracy, limits of quantification (LOQ) and repeatability for water soluble vitamins B group. An excellent linearity ($r^2=0.999$) was observed for vitamin $B_1$, vitamin $B_2$, nicotinic acid, nicotinamide, vitamin $B_6$ in the concentration range ($0.1{\sim}2{\mu}g/mL$). Observed recovery of vitamin $B_1$ was found to be between 100 and 103%, vitamin $B^2$ was found to be between 104 and 112%, nicotinic acid was found to be between 82 and 85%, nicotinamide was found to be between 121 and 124% and vitamin $B_6$ was found to be between 95 and 104%. LOQ of vitamin $B_1$ was found to be $0.04{\mu}g/mL$, vitamin $B_2$ was found to be $0.05{\mu}g/mL$, nicotinic acid was found to be $0.15{\mu}g/mL$, nicotinamide was found to be $0.08{\mu}g/mL$ and vitamin $B_6$ was found to be $0.63{\mu}g/mL$. Repeatability precision for vitamin $B_1$ was found to be 0.4%, vitamin $B_2$ was found to be 0.4%, nicotinic acid was found to be 0.5%, nicotinamide was found to be 0.7% and vitamin $B_6$ was found to be 0.4% relative standard deviation (RSD). Also, verify the accuracy of the simultaneous analysis methods, we monitored the labeled contents of the health functional foods and children's preferred foods.

• Journal of the Korean Magnetics Society
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• v.23 no.5
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• pp.154-158
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• 2013

We have analyzed the magnetization curves measures by using VSM and MOKE in synthetic antiferromagnetic coupled CoB/Ru/CoB thin film. The measured results were compared with calculated ones by Stoner-Wohlfarth model based on the magnetization behavior of two ferromagnetic layers ($M_1$, $M_2$). The calculated total magnetization ($M_{tot}=M_1+M_2$) and single layer magnetization($M_1$) behaviors were compared with measured results by using VSM and MOKE, respectively. The total magnetization curve ($M_{tot}=M_1+M_2$) showed reversible magnetization behavior with flopping field of about 50 Oe. While single layer magnetization ($M_1$) behaviors showed irreversible magnetization behavior in the field range of $H_F$ < H < $H_F$. These magnetization behaviors were explained by the angle difference between magnetization directions of two ferromagnetic layers in SAF sample.

• Kyungpook Mathematical Journal
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• v.56 no.3
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• pp.737-743
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• 2016

Let a and b be two ideals of a commutative Noetherian ring R, M a finitely generated R-module and i an integer. In this paper we study formal local cohomology modules with respect to a pair of ideals. We denote the i-th a-formal local cohomology module M with respect to b by ${\mathfrak{F}}^i_{a,b}(M)$. We show that if ${\mathfrak{F}}^i_{a,b}(M)$ is artinian, then $a{\subseteq}{\sqrt{(0:{\mathfrak{F}}^i_{a,b}(M))$. Also, we show that ${\mathfrak{F}}^{\text{dim }M}_{a,b}(M)$ is artinian and we determine the set $Att_R\;{\mathfrak{F}}^{\text{dim }M}_{a,b}(M)$.

• Bulletin of the Korean Mathematical Society
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• v.36 no.4
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• pp.671-682
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• 1999

Using a base-point free version of the infinite symmetric product we define a fibrewise infinite symmetric product for any fibration $E\;\longrightarrow\;B$. The construction works for any commutative ring R with unit and is denoted by $R_f(E)\;l\ongrightarrow\;B$. For any pointed space B let $G_I(B)\;\longrightarrow\;B$ be the i-th Ganea fibration. Defining $M_R-cat(B):= inf{i\midR_f(G_i(B))\longrihghtarrow\;B$ admits a section} we obtain an approximation to the Lusternik-Schnirelmann category of B which satisfies .g.a product formula. In particular, if B is a 1-connected rational space of finite rational type, then $M_Q$-cat(B) coincides with the well-known (purely algebraically defined) M-category of B which in fact is equal to cat (B) by a result of K.Hess. All the constructions more generally apply to the Ganea category of maps.

• Journal of the Korean Society of Fisheries and Ocean Technology
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• v.23 no.4
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• pp.163-168
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• 1987

The underwater observation of the ambient noise and the noise generated by the engine revolution in a ship was carried out in July to August, 1984, 1985 and 1987, near around some ports and in the Eastern Sea of Korea. Vertical distribution of the sound pressure of both noises were observed and the spectrum characteristics were analysed and compared. The results obtained are summarized as follows: 1. Sound pressure level of the ambient noise at 5m deep layer in calm sea condition (wind speed 0-2m/s) near around the ports were observed as 108dB at the eastern part of Pusan port, 106dB at the southern part of Pusan port and 101dB at Kuryongpo port. It shows that the level near around the large port which contains much noisy resources is higher than the small port. The level at 5m deep layer in the open sea, in the mid-region between Korean Peninsula and Ulnung Island was observed as 100dB. It mean that the level in the open sea is lower than that around the ports. The level at 20m and 70m deep layer were 1-2dB lower than that at 5m deep layer, and that at deeper layer than 100m was almost constantly 100dB around. 2. Sound pressure level of the ambient noise at 5m deep layer in windy open sea condition (wind speed 10-15m/s) was 108dB, and was gradually decreased in accordance with the increase of depth with representing 100dB at 70m deep layer and that at deeper layer was almost constantly 100dB. The level of the noise generated by engine revolution was 146, 125, 112, 110, 104dB at 5, 50, 100, 150 and 200m deep layer respectively. It means that the level decrease with the depth. 3. Spectrum level of the ambient noise at 5m deep layer with the frequency band of 10 Hz, 100 Hz, 1 KHz, 10 KHz, in the windy sea condition were 86, 75, 61, 32dB respectively and the level of the noise generated by engine revolution was 105, 95, 86, 55dB respectively. It means that the latter are about 20dB higher than the former. The level of the former at 200m deep layer was 80, 68, 47, 26dB and the latter 82, 70, 59, 31dB. It means that the latter are about 4dB higher than the former.

• Environmental Mutagens and Carcinogens
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• v.19 no.1
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• pp.34-38
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• 1999

Fumonisin B1 is a secondary metabolite of Fusarium moniliforme, a contaminant of corn and corn product. Fumonisin B1 has been shown to be responsible for major toxicological effects of the fungus in rats, horses, and pigs. Fumonisin B1 induced λ DNA fragmentation, which was increased with incubation time, reducing agent NADPH and metal ion (Cu2+). The DNA damage was inhibited by dimethyl sulfoxide (DMSO) or mannitol as radical scavenger for free radicals. DNA fragmentation, induced by fumonisin B1 in the presence of 1 mM NADPH and 0.1 mM CuCl2, was inhibited by 100 mM DMSO. By the in vitro reaction of fumonisin B1 with supercoiled plasmid pBR322 DNA, plasmid DNA was relaxed, eventually linearized in the agarose gel electrphoresis. From rifampicin sensitive E. coli CSH138 in bacterial mutagenesis system, the rifampicin resistant E. coli mutants were obtained by fumonisin B1. These results suggest that fumonisin B1 may be a possible environmental mutagen in bacterial mutagen assay system.

• Journal of Ginseng Research
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• v.45 no.6
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• pp.734-743
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• 2021

Background: The underlying mechanisms of the potential tumor-suppressive effects of ginsenoside Rh2 are complex. N6-methyladenosine (m6A) RNA methylation is usually dysregulated in cancer. This study explored the regulatory effect of ginsenoside Rh2 on m6A RNA methylation in cancer. Methods: m6A RNA quantification and gene-specific m6A RIP-qPCR assays were applied to assess total and gene-specific m6A RNA levels. Co-immunoprecipitation, fractionation western blotting, and immunofluorescence staining were performed to detect protein interactions and distribution. QRT-PCR, dual-luciferase, and ChIP-qPCR assays were conducted to check the transcriptional regulation. Results: Ginsenoside Rh2 reduces m6A RNA methylation and KIF26B expression in a dose-dependent manner in some cancers. KIF26B interacts with ZC3H13 and CBLL1 in the cytoplasm of cancer cells and enhances their nuclear distribution. KIF26B inhibition reduces m6A RNA methylation level in cancer cells. SRF bound to the KIF26B promoter and activated its transcription. SRF mRNA m6A abundance significantly decreased upon KIF26B silencing. SRF knockdown suppressed cancer cell proliferation and growth both in vitro and in vivo, the effect of which was partly rescued by KIF26B overexpression. Conclusion: ginsenoside Rh2 reduces m6A RNA methylation via downregulating KIF26B expression in some cancer cells. KIF26B elevates m6A RNA methylation via enhancing ZC3H13/CBLL1 nuclear localization. KIF26B-SRF forms a positive feedback loop facilitating tumor growth.

• Kyungpook Mathematical Journal
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• v.60 no.1
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• pp.53-69
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• 2020

Let (A, M) ⊂ (B, N) be commutative quasi-local rings. We consider the property that there exists a ring D such that A ⊆ D ⊂ B and the extension D ⊂ B is inert. Examples show that the number of such D may be any non-negative integer or infinite. The existence of such D does not imply M ⊆ N. Suppose henceforth that M ⊆ N. If the field extension A/M ⊆ B/N is algebraic, the existence of such D does not imply that B is integral over A (except when B has Krull dimension 0). If A/M ⊆ B/N is a minimal field extension, there exists a unique such D, necessarily given by D = A + N (but it need not be the case that N = MB). The converse fails, even if M = N and B/M is a finite field.

• Journal of the Microelectronics and Packaging Society
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• v.8 no.4
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• pp.17-23
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• 2001

The 3-D Hall sensor has two horizontal magnetic field sensing parts ($\chi$, y components) and one vertical magnetic field sensing part (z component). For conventional, 3-D Hall sensor it is general that the sensitivity for $B_{z}$ is about 1/10 compared with those for $B_\chi$ or $B_y$. Therefore, in this work, we proposed 3-D Hall sensor with new structure. We have increased the sensitivity about 6 times to form the trench using anisotropic etching. And we have increased the sensitivity for the $B_z$ by 80% compared with those of $B_\chi$ and$B_y$ using deposition of the ferromagnetic thin films on the bottom surface of the wafer to concentrate the magnetic fluxes. When the input current was 3 mA, sensitivities of the fabricated sensor with Ni/Fe film for $B_\chi, B_y$ and $B_{z}$ were measured as 120.1 mV/T, 111.7 mV/T, 95.3 mV/T, respectively. The measured linearity of the sensor was within $\pm$3% of error.

• Journal of the Korean Magnetics Society
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• v.21 no.1
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• pp.15-22
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• 2011

It is necessary to describe the hysteresis characteristics of magnetic material precisely for the analysis or design of system with ferromagnetic materials. Although Preisach model is regarded as the most accurate method to describe the hysteresis characteristics, it is not widely applied to the real systems because of some difficulties. The conventional Preisach model shows the numerical instabilities during the iterative computations because the density distribution obtained from the sets of M-H curves are strongly localized. To remove such numerical instabilities, M-B instead of M-H is adopted as an implementation variable in normal Preisach modeling. The two dimensional computations with hysteresis characteristics by using normal Preisach modeling are tested and the result showed that the modeling by using M-B variables showed better stabilities than M-H variables.