• 대한의용생체공학회:의공학회지
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• 제22권5호
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• pp.393-402
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• 2001

전체 심혈관계의 혈류역학적 특성을 분석할 수 있는 수치해석 방법을 개발하였다. 이는 12개의 요소들로 구성된 lumped parameter모델에 기초하고 있으며 인체의 신경계에 의한 자율조절기능을 모사하기 위해 주로 혈압의 단기적 조절을 위한.baroreflex system뿐 아니라 cardiopulmonary reflex 메커니즘가지도 구현하여 모델에 포함시켰다. 또한 교감 및 부교감 신경에 의한 자극-반응 전달을 구현함에 있어 생리학적 데이터에 기초한 방법을 사용하였다. 본 연구의 수치해석 코드를 검증하기 위하여 우선 보통 상태의 심혈관계에 대하여 혈류역학적 계산 결과를 기존의 참고문헌들에서의 값들과 비교 검토하였다. 심혈관계 모델의 혈류역학적 자극에 대한 반응 결과를 조사하기 위하여. 20% 출혈이 발생하는 경우와 LBNP(Lower Body Negative Pressure) 모사를 수행하였다. 두 경우 모두. 비교적 실험치와 잘 일cl하고 있음을 확인할 수 있었다. 특히 LBNP 수행 시, 외부압력의 크기가 커질수록 baroreflex만을 포함하고 있는 방법은 baroreflex와 cardiopulmonary reflex 모두를 포함하고 있는 방법에 비하여 다소 부정확한 결과를 보여주고 있는데. 이는 cardiopulmonary reflex 메커니즘의 중요성을 보여주고 있다.

• 대한화장품학회:학술대회논문집
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• 대한화장품학회 2003년도 IFSCC Conference Proceeding Book I
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• pp.611-616
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• 2003

Korean ginseng(Panax Ginseng C.A. Meyer) known as a oriental miracle drug is an important medicinal plant. Ginseng has been used for geriatric, tonic, stomachic, and aphrodisiac treatments for thousands years. Also, it is an antibiotic and has therapeutic properties against stress and cancer. Ginseng is widely distributed all over the world. Among them, Korean mountain ginseng has the most valuable effect on pharmaceuticals. The roots of mountain ginseng contained several kinds of ginsenosides that have many active functions for the human body. However, the study of mountain ginseng has a limit because the mountain ginseng is very expensive and rare. So, we artificially cultured mountain ginseng adventitious roots using the bioreactor culture system. We induced callus from original mountain ginseng, directly dug up in mountain and aged about one hundred ten years. Separated adventitious roots were precultured in 500ml conical flasks and then, transferred in 20L bioreactors. The adventitious roots of mountain ginseng were harvested after culturing for 40days, dried and then, extracted with several solvents. In this study, we investigated the whitening effect, anti-wrinkle effect and the safety of tissue cultured adventitious roots extract of mountain ginseng in order to identify the merit as a cosmetic ingredient. Particularly, extract of mountain ginseng adventitious roots showed whitening and anti-wrinkle effects. The inhibitory effect of this extract on the melanogenesis was examined using B-16 melanoma cell. When B-16 melanoma cells were cultured with adventitious root extract, there was a dramatically decrease in melanin contents of 8-16 melanoma cell. And we identified this extract inhibited Dopa auto-oxidation significantly. Also, when transformed mouse fibroblast L929 cells were treated with this extract, there was a significant increase in collagen synthesis. The results show significant inhibited melanization and wrinkle without inhibiting cell viability.

• 한국정보전자통신기술학회논문지
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• 제2권3호
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• pp.23-29
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• 2009

심박수는 심장이 혈액을 전신에 보낼 때에 고동치는 속도, 즉 매 분당 박동수를 말하 며 성인남자의 경우 보통 1분동안 60~80회가 정상적이다. 심박수가 정상보다 적으면 서맥, 많으면 빈맥이라 하며 이 경우 여러 가지 질병에 걸릴 수 있으며 상황에 따라 사망에 이르기까지도 한다. 따라서 심박수는 건강한 생활에 매우 중요한 역할을 하고 있다. 본 연구에서는 ECG를 통하여 심박수를 자동 추출하는 방법에 관하여 연구하였다. 육안으로 측정한 심박수를 기준으로 첫째 ECG를 2차 미분을 이용하여 심박수를 추출하는 방법과 자기상관함수를 이용하여 심박수를 추출한 방법으로 구한 심박수를 비교하여 고찰 하였다. 실험 데이터는 MIT/BIH Database를 이용하였다.

• 대한방사선기술학회지:방사선기술과학
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• 제42권1호
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• pp.25-30
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• 2019

Whole Spine Scanography (WSS) using the Digital Radiography (DR) system is an examination that requires whole body X-ray exposure, which involves more exposure to radiation for patients than other general radiographies. This can affect the occurrence of breast cancer. This research measured radiation dose when breasts were shield and not shield using the Auto Exposure Control (AEC) mode. The radiation dose without a shield was 1.540 mGy, and that using a collimator was measured 0.506 mGy. Moreover, 0.733 mGy was measured when 1 shield (0.3 mm) was used, and $0.523{\mu}Gy$ when 5 of them (1.5 mm) were used. The results showed that the radiation dose with 5 shields and the radiation dose with a collimator were similar. Moreover, 0.233 mGy was measured when 8 shields (2.4 mm) were used. The standard deviation were 0.081 when using collimator and 0.014 when 5 shields were used. Also, when 8 shields were used, it was found to be 0.002. Most patients who go under a scoliosis test are children or young people who are highly sensitive to radiation. In the research results, the case where the organs sensitive to radiation, women's breasts, were shielded showed more distinct differences compared to without shields. It is considered that using shields can provide more constant shield than using a collimator and lower the risk of breast cancer caused by exposure to radiation.

• 한국CDE학회논문집
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• 제21권2호
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• pp.186-195
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• 2016

The finite element modeling of a ship for hull structural analysis on the basis of new harmonized common structural rules (CSR-H) is to be extended to the cargo holds in fore and after body of a ship. Unlike the parallel middle-body where the external and internal features of hull are equal along to the longitudinal direction of a ship, in fore and after body, the external and internal features of hull vary linearly or even irregularly in forms of a surface or a curve along to the longitudinal direction of a ship. Thus, it needs lots of design man-hours for the modeling for structural analysis. In order to save man-hours in initial structural design phase of a ship, the specified 3D CAD system has been adopted in shipbuilding industry. Through the interface between CAD and CAE (rule scantling and direct strength assessment), design man-hour in initial design phase can be saved even under the environment of CSR-H.

• 한국의류학회지
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• 제32권5호
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• pp.846-858
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• 2008

This study was designed to propose a method to draft bodice block pattern from 3D body scan data. Subjects were ten elderly women in their 60's, who wear basic size(B: 94cm, W: 82cm) garment. Scanning was done using 3D whole body scanner(WB4, Cyberware). Measurements for 3D data and cross section were attained using Auto CAD, by which a upper bodice pattern for elderly women was drawn on the basis of short measured method. The results are as following: As for most items, no significant differences were shown between measurements from Martin's anthropometry and those from 3D scan data, suggesting measurement from 3D scan data could be used to draft a pattern. The drafting equations acquired were as follows; width of pattern=B/2+5.5, width of waist=W/2+3.5cm, dart amount=8cm. Dart distributions were 23%(B.P.) : 20%(front armpit) : 17%(side seam) : 18%(back armpit) : 15%(back protruded point) : 7% (center back line). Through wearing test using 5-point Likert scale, resultant pattern was evaluated as appropriate for elderly women's pattern to get over 4 point. As a result, it might be said that 3D scanning application is effective for elderly women in that it doesn't take time so much as Martin's anthropometry and that their body shape vary compared with those of young women.

• 핵의학기술
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• 제21권2호
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• pp.55-64
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• 2017

최근 SPECT/CT의 보급과 함께 다양한 영상보정 방법들을 빠르고 정확하게 적용할 수 있게 되면서, 영상품질 향상과 더불어 정량적 정확성까지 기대할 수 있게 되었다. 그중 Collimator Detector Response (CDR) 회복(recovery)은 검출기면의 거리로부터 발생된 blurring 효과를 보상하여 분해능 회복을 목적으로 하는 보정방법이다. 본 연구에서는 SPECT/CT 영상에서 CDR recovery 가 적용되었을 때 검출거리 변화에 따른 정량적 변화를 알아보고자 하였다. 검출거리의 변화에 따른 획득 계수의 차이를 알아보고자 검출거리를 궤도방식(obit type)에 따라 Circular는 X, Y축 반경 30 cm, Non-Circular는 X, Y축 반경 21 cm, 10 cm, Non-Circular Auto(=Auto Body Contouring_ ABC, spacing limit 1 cm)로 설정하였고, 재구성 방법은 CDR recovery(CDRr)의 사용 유/무에 따른 계수 회복 차이를 알아보고자 OSEM (w/o CDRr)와 Astonish(3D-OSEM with CDRr)로 구분하여 적용하였다. 이 때 감쇠, 산란, 붕괴 보정은 모든 영상에 공통 적용하였다. 정량적 평가를 위해 교정인자(calibration factor_CF) 산출을 목적으로 교정영상(cylindrical phantom, $^{99m}TcO_4$ 123.3 MBq, 물 9293 ml)을 획득하였고, 팬텀 실험을 위하여 50 cc 주사기에 물 31 ml를 채우고 $^{99m}TcO_4$ 123.3 MBq를 설정하여 팬텀영상을 획득하였다. 팬텀 영상에서 주사기 전체 체적에 VOI(volume of interest)를 설정하여 각 조건별로 총 계수 값을 측정하였고, CF를 적용시켜 설정된 참값 대비 추정값의 오차를 구하여 보정에 따른 정량적 정확성을 확인하였다. 산출된 CF는 154.27 (Bq/ml/cps/ml)이며, 각 조건별 영상에서 참값 대비 추정값은 OSEM에서 Circular 86.5%, Non-Circular 90.1%, ABC 91.3% Astonish에서 Circular 93.6%, Non-Circular 93.6%, ABC 93.9%으로 분석되었다. OSEM은 검출거리가 가까울수록 정확성이 높아졌으며, Astonish의 경우에는 거리와 상관없이 거의 유사한 값을 나타내었다. 오차는 OSEM Circular(-13.5%)에서 가장 크고, Astonish ABC(-6.1%)에서 가장 적었다. SPECT/CT영상에서 CDR recovery 적용을 통한 거리보상이 이루어 졌을 때 검출거리가 먼 조건에서도 근접검출과 거의 동일한 정량적 정확성을 보였고, 검출거리의 변화에 영향을 받지 않고 정확한 보정이 가능한 것을 확인 할 수 있었다.

• 한국문헌정보학회지
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• 제23권
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• pp.207-261
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• 1992

The purpose of this study is (1) to design and test a database which can be automatically classified, and (2) to generate automatic classification number by processing the keywords in titles using the code combination method of Colon Classification(CC) as well as an automatic recognition of subjects in order to develop an automatic classification system (Auto BC System) based on CC which can be applied to any research library. To conduct this study, 1,510 words in the fields of agricultrue and medicine were selected, analized in terms of [P], [M], [E], [S], [T] employed in CC, and included in a database for classification. For the above-mentioned subject fields, the principle of an automatic classification was specified in order to generate automatic classification codes as well as to perform an automatic subject recognition of the titles included. Whenever necessary, editing, deleting, appending and reindexing of a database can be made in this automatic classification system. Appendix 1 shows the result of the automatic classification of books in the fields of agriculture and medicine. The results of the study are summarized below. 1. The classification number for the title of a book can be automatically generated by using the facet principles of Colon Classification. 2. The automatic subject recognition of a book is achieved by designing a database making use of a globe-principle, and by specifying the subject field for each word. 3. The automatic subject-recognition of input data is achieved by measuring the number of searched words by each subject field. 4. The combination of classification numbers is achieved by flowcharting of classification formular of each subject field. 5. The efficient control of classification numbers is achieved by designing control codes on the database for classification. 6. The automatic classification by means of Auto BC has been proved to be successful in the research library concentrating on a Single field. The general library may have some problem in employing this system. The automatic classification through Auto BC has the following advantages: 1. Speed of the classification process can be improve. 2. The revision or updating of classification schemes can be facilitated. 3. Multiple concepts can be expressed in a single classification code. 4. The consistency of classification can be achieved with the classification formular rather than the classifier's subjective judgement. 5. A user's retrieving process can be made after combining the classification numbers through keywords relating to the material to be searched. 6. The materials can be classified by a librarian without subject backgrounds. 7. The large body of materials can be quickly classified by means of a machine processing. 8. This automatic classification is expected to make a good contribution to design of the total system for library operations. 9. The information flow among libraries can be promoted owing to the use of the same program for the automatic classification.

• 한국균학회지
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• 제36권1호
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• pp.51-57
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• 2008

식용과 약용버섯으로서 이용가치가 높은 것으로 알려진 먹물버섯(C. comatus)에 대하여 보다 우수한 인공재배법을 개발하고 자실체의 형태적 특성에 대한 연구 결과는 다음과 같다. 먹물버섯속균 5개 균주 중에서 C. comatus균인 CM 980301 균주를 우량균주로 선발하였으며, 먹물버섯(C. comatus: CM 980301)자실체를 생산하기 위한 우수 배지는 종균용으로 밀곡립배지를 사용하고, 먹물버섯을 볏짚 발효배지에 인공재배 하였을 때 $24{\sim}28^{\circ}C$에서 균배양은 종균 접종 후 15일, 복토 후 13일이 소요되었으며, 원기형성 및 초발이는 $20{\sim}24^{\circ}C$에서 $10{\sim}11$일이 소요되었고, 버섯생육은 $20{\sim}24^{\circ}C$에서 $7{\sim}8$일이 소요되었다. 먹물버섯 (CM 980301)의 수확적기는 갓이 피기 전으로 자실체 경도는 갓 $102{\sim}169\;g/cm^2$, 대 $126{\sim}182\;g/cm^2$으로 단단하였고, 인공재배한 수량성은 $37.7kg/3.3m^2$, 개체중 17.9 g이었다.

• 한국식품영양과학회지
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• 제10권1호
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• pp.77-84
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• 1981

The effect of sesame of L-lysine HCI and sesame supplementing a wheat flour diet on growth, liver lilpid content, and on the free amino acid levels in the plasma and liver was studied in young male rats with an initial body weight of $75{\pm}3g$. The free amino acids were analyzed by amino acid auto analyzer (JLC - 6HA, NO. 310). The results were as follows. The body weitht gain on L-lysine HCI and sesame supplemented diet was more than weight in the sesame added diet or wheat flour diet groups. Also the liver lipid contents of rats on a wheat flour diet supplemented with L-lysine HCI and sesame showed greater increases than the levels in rats on the wheat flour diets. The rate of liver lipid accumulation was depressed in rats fed L-lysine HCI supplemented wheat flour containing sesame than in rats fed soybean oil or shortening oil instead of sesame. The free phe. Tyr. Leu. Ileu. Val. Lys. levels in the plasma of rats administered the wheat flour diets supplemented with 0.25% L-lysine HCI were higher than those of rats without L-lysine HCI. The free phe. Tyr. Asp. His. Lys. contained in the liver were increased, but other free amino acids were decreased according to the L-lysine HCI amount.