• Journal of Soil and Groundwater Environment
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• v.12 no.1
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• pp.1-35
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• 2007

In the last decades, the decrease in biological or chemical availability of sorbed contaminants as contact time passed, is generally accepted. This phenomenon so called as "aging" or "sequestration" is known to directly affect risk of the contaminats. This was observed for mainly for hydrophobic organic contaminants (HOCs), but also reported for heavy metals. Aging is known to be directly related to sorption-desorption hysteresis, irreversible sorption, desorption-resistance, nonequilibrium sorption, etc. The decrease in bioavailability due to aging or sequestration indicates realistic decrease in risk potential. Recently a risk-based management concept by scientific evidences but not the simple measurement of contaminant concentration has been attempted to determine environmentally acceptable remedial endpoint. This is because selection of remedial endpoint based on not total concentration but the bioavailability and toxicity of contaminants can reduce both the treatment cost and remedial activities of the contaminated sites. The bioavailability and toxicity of the residual contaminants are highly affected by the fate and transport and also directly affect the exposure pathways and bioaccumulation of contaminants in the living biota. In this paper, scientific feasibility on the risk-based clean-up and management of contaminated sites is reviewed.

• Research in Community and Public Health Nursing
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• v.7 no.1
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• pp.129-137
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• 1996

The purpose of this study is to examine the medicalizing process of menopanse with literature review, and then is to explore the knowledge of 'menopausal syndrome' critically, focused on four critics on the biomedical model which were suggested by Mishler. Although menopause is a natural biological phenomenon, the view of many medical researchers and practitioners is that menopause is a disease. After synthetic estrogen was developel in 1938, physicians did agree on two basic assumptions : menopausal women should be managed by physicians, and medical intervention should be given. Menopouse was defined as a deficiency disease (estrogen difficiency) by Wilson in 60's and is redefined as a cause of disease(for example, osteoporosis, heart disease) at the present. But the other view of non-medical researcher is that 'menopausal syndrome' as a disease is constructed medically. It was reported that Only hot flush and sweating of physical symptoms experienced by menopausal women, were associated with menopause. Symptoms of menopausal syndrome are also related with symptons of aging. So, it cann't conclude that menopausal syndrome is resulted from menopause, and it cann't be only explained that menopausal syndrome is related causally to estrogen deficiency, and only treatment by ERT or HRT is best relevant. It cann't assume that menopausal syndrome is a common phenomenon to all menopause women, because culture affected on women's experience of menopause.

• The Journal of the Institute of Internet, Broadcasting and Communication
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• v.20 no.3
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• pp.129-134
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• 2020

Moisture infiltration inside the solar cell module, filling of EVA sheet, melting of the frame seal, and deterioration of power generation performance in the module one year after installation are occurring. Whitening phenomenon, electrode corrosion phenomenon, and dielectric breakdown phenomenon are appearing in solar cell module installed in Korea before 5-7 years, leading to deterioration of power generation performance, and big problems for long-term reliability and long life technology are emerging. Therefore, in order to solve these problems, the development of a micro inverter (MiCrco Inverter Converter, MiC) including the function of securing the durability of the solar cell module and monitoring the aging progress and the solar cell based on the monitoring data from the MiC smart monitoring programs have been proposed to determine the aging of modules. In addition, in order to become a highly efficient solar smart monitoring system through systematic operation management through IT convergence with MiC that has enhanced monitoring function of solar cell module, SoC(System On Chip) in micro inverter is the environment for solar cell module. There is a demand for functions that can detect information in a complex manner and perform communication and control when necessary. Based on these requirements, this paper aims to develop SoC-based low-cost MiC smart photovoltaic system technology.

• Korean Journal of Plant Resources
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• v.32 no.6
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• pp.633-643
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• 2019

Long-term ultraviolet (UV) exposure accelerates the phenomenon of skin photo-aging by activating collagenase and elastase. In this study, we aimed to investigate the effects of a combination of grapefruit and rosemary extracts (cG&Re) on UVB-irradiated damage in HaCaT cells and dorsal mouse skin. In HaCaT cells, cG&Re recovered UVB-reduced cell viability and inhibited protein expression of mitogen-activated protein kinases (MAPKs), such as extracellular signal-regulated kinases (p-Erk), c-Jun N-terminal kinases (p-JNK), and a class of MAPKs (p-P38). Also, cG&Re suppressed UVB-induced collagen and elastin degradation by decreasing matrix metalloproteinases (MMPs) and nuclear factor kappa light chain enhancer of activated B cells (NF-κB) expression, which is a transcription factor. Similar results were observed in dorsal mouse skin. Taken together, our data indicate that cG&Re prevent UVB-induced skin photo-aging due to collagen/elastin degradation via activation of MAPKs, MMPs, and the NF-κB signaling pathway in vitro and in vivo.

• Journal of Korean Society of Occupational and Environmental Hygiene
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• v.25 no.4
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• pp.573-583
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• 2015

Objectives: This study was carried out to evaluate the effect of noise exposure and aging on changes in hearing threshold level and the relationship between age and noise. Materials: The author selected 274 male shipyard and assembly line workers as the noise exposed group and 582 males not exposed to noise as the general population group. Data were collected from five years of consecutive annual audiometric tests performed from 2008 to 2012. Results: In the general population and noise exposed groups, there was a reverse phenomenon that hearing threshold level for 2009 was lower than that of 2008, which seemed to be due to the learning effect, but from 2010 hearing threshold level increased. In the noise exposed group, the mean hearing threshold level in the left ear was significantly higher than that for right ear. In the general population group, the older was the age, the higher was the hearing threshold level, especially at 4000 Hz. In the general population and noise exposed groups, frequency, age group and noise exposure independently affected hearing threshold level, and there was no relationship between age and noise exposure. Over all frequencies, the change of hearing threshold level was larger in the noise exposed group than in the general population group. In the noise exposed group below thirty years old, the change at 4000 Hz was remarkable. Conclusions: Age and noise exposure seem to affect hearing threshold level independently and contribute to an additive effect on hearing threshold level.

• Journal of Korean Society of Rural Planning
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• v.19 no.2
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• pp.75-91
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• 2013

In rural areas, in spite of the development projects of town and houses has been performed after the New Community Movement, due to rapid industrialization and urbanization, which lasted until the 2000s from the 1980s, out-migration to the cities, changes in the industrial structure, rapid aging was carried. As a result, the gap of housing environment between urban and rural areas became more serious. The meantime, the housing problem is recognized only to the problems of the big cities, mostly urban public housing policy oriented. However, when you check the indicator of the housing environment, such as the percentage of aging housing, rural environment has become a relatively poor compared to the city. In addition, due to a decrease in income and aging of the population living in rural areas of existing infrastructure to improve the living environment is weakened. And inside of the rural areas, changes in the housing environment and polarization phenomenon is becoming increasingly serious. Therefore, in this study, there is a purpose to be presented the improvement direction for efficient implementation of house remodeling support program for underprivileged group in rural areas and requires immediate attention improvement of housing environment. Previously, House remodeling support project in rural areas was carried out at the initiative of local governments and government mainly. For this reason, it is difficult due to limited institutional, to reflect the necessary parts directly to the real life of the residents. And, the demand for improvement of housing environment need modifications to solve the inconvenience of life of residents directly in many cases. It is considered that community-based house remodeling support project is to be carried out through the participation of local residents.

• Journal of Digital Convergence
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• v.18 no.11
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• pp.87-97
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• 2020

This study summarized longevity factors of enterprises and presented longevity mechanism. By analogy of human aging and corporate longevity, the company's decline and longevity phenomenon were analyzed to derive corporate longevity mechanism, presented domestic and foreign longevity enterprises' cases study using above mechanism. The longevity mechanism first, as the human body restricts free radicals by dietary restrictions, companies also need continuous input efficiency. Second, as cognitive reserve by high thinking activities helps heath lifespan, companies can strengthen their profitability by continuous R&D. Third, as humans improve antioxidant functions by exercise, companies should develop risk management capabilities for environmental changes. This study can contribute to sustainable strategies for corporate managers, ultimately plan to suggest model of evaluation or diagnosis of corporate longevity.

• KIEAE Journal
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• v.10 no.2
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• pp.9-18
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• 2010

As an aging population has increased vastly and nuclear families have been a dominating family type in modern Korean society, the numbers of the elderly who suffer Empty Nest Syndrome and LID (Loss Isolation Depression) syndrome have been accelerated. These syndromes involve psychological instability, melancholy, and lethargy. To make the elderly get out of this phenomenon and live actively, the scheme of converting their existing house into shared housing was set as a hypothetical solution in this study. This study sets out to find out responses of the elderly to alter their own house's function in housing improvement area. A Small Workshop Panel method was used and the elderly aged 55 years upwards took part and they own a detached house in a housing improvement area that is relatively large for the elderly or the elderly couple to live alone. Through the workshop, problems that the elderly have been experiencing within their houses were looked into and responses of the elderly on altering their house to shared housing by introducing developed schematic plans. Although, the first response was negative, positive responses from the house owners were carried out when a visual support i.e. developed shared housing plan was provided. The positive response was based on the fact that subsidies from the government on house renovation and tenants matching programs are supported as shared housing could provide home owners economical support with rents and help them to feel less lonely. This is a way of relieving the elderly from being neglected and supporting them to live and age actively in their later lives. Furthermore, by providing a visual media to the elder residents in housing improvement area, their greater understandings on the development and addressing their opinions were possible. Therefore, more tools that promote elder residents' participation are needed for future housing improvement projects and an aging society.

• Journal of the Korean association of regional geographers
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• v.11 no.2
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• pp.187-210
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• 2005

The purpose of this study is to examine the spatial characteristics of the longevity phenomenon and long-live areas in Korea where a rapid aging process is undergoing. Population data from 1966 to 2000 at the county level are analyzed to understand aging process and changes of longevity degree by regions. The relationship between the degree of longevity and a region's natural environments and distance to a metropolis has been analyzed to understand regional factors of longevity. The findings from the study are summarized as follows. Firstly, the rural regions in Honam show the highest degree of longevity in the nation. Secondly, the areas of the high degree of longevity has recently shifted and/or expanded from the islands and seashore areas of southwestern region to inland mountainous areas around Soback Mountain. Southern islands and seashore regions used to show the nation's highest degree of longevity in the 1970s. Thirdly, the analysis of regional environment factors indicated that longevity has more related to a precipitation and an average altitude than temperature. Fourthly, in order to identify the longevity factors in urban areas, social and economic factors should be considered beyond the natural environmental factors.

• Mycobiology
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• v.50 no.5
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• pp.366-373
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• 2022

Regulation of proper gene expression is important for cellular and organismal survival, maintenance, and growth. Abnormal gene expression, even for a single critical gene, can thwart cellular integrity and normal physiology to cause diseases, aging, and death. Therefore, gene expression profiling serves as a powerful tool to understand the pathology of diseases and to cure them. In this study, the difference in gene expression in Flammulina velutipes was compared between the wild type (WT) mushroom and the mutant one with clogging phenomenon. Differentially expressed transcripts were screened to identify the candidate genes responsible for the mutant phenotype using the DNA microarray analysis. A total of 88 genes including 60 upregulated and 28 downregulated genes were validated using the real-time quantitative PCR analysis. In addition, proteomic differences between the WT and mutant mushroom were analyzed using two-dimensional gel electrophoresis and matrix-assisted laser desorption/ionization-time of flight (MALDI-TOF). Interestingly, the genes identified by these genomic and proteomic analyses were involved in stress response, translation, and energy/sugar metabolism, including HSP70, elongation factor 2, and pyruvate kinase. Together, our data suggest that the aberrant expression of these genes attributes to the mutant clogging phenotype. We propose that these genes can be targeted to foster normal growth in F. velutipes.