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The Relationship of Repeated Racehorse Simulator Exercise on Plasma Ghrelin and Hormons in Jockeys (반복적인 모형마 운동에 따른 기수의 혈장 그렐린과 호르몬들의 관계)

  • Zhang, Seok-Am
    • Journal of the Korea Academia-Industrial cooperation Society
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    • v.12 no.4
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    • pp.1756-1762
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    • 2011
  • The aim of the present investigation was to investigate the relationship of repeated racehorse simulator exercise on plasma ghrelin and hormons in fasted jockeys. The fasted jockeys and apprentice jockeys performed $1^{st}$ short distance 1000m, $2^{nd}$ middle distance 1700m and $3^{rd}$ long distance 2300m racehorse simulator exercises, and venous blood samples were obtained before, immediately after. In addition to ghrelin concentration, leptin, insulin, insulin-like growth factor-1 (IGF-1), and cortisol values were measured. Pearson correlation coefficients revealed plasma ghrelin and insulin concentration in apprentice jockeys r=.55 after the $3^{rd}$ exercise. There were relationships between significant relationships (p<.05) between plasma ghrelin and leption concentration in jockeys r=.73, and between plasma ghrelin and cortisol concentration in apprentice jockeys r=.64 before exercise. There was no difference in the ghrelin, leptin, insulin and IGF-1 concentration responses to the consecutive exercise. The IGF-1 and cortisol level showed significant (p<.05)difference between groups. In conclusion, these results suggest that negative energy balance induced by of repeated racehorse simulator exercise elicits a metabolic response with positive relationship in plasma ghrelin and insulin in apprentice jockeys after the $3^{rd}$ exercise.

Video-Assisted Thoracic Surgery Under Epidural Anesthesia -in High-Risk Group (경막외마취하에 비디오 흉강경수술 - 고위험군에서)

  • Lee, Song-Am;Kim, Kwang-Taik;Kim, Il-Hyeon;Park, Sung-Min;Baek, Man-Jong;Sun, Kyung;Kim, Hyoung-Mook;Lee, In-Sung
    • Journal of Chest Surgery
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    • v.32 no.8
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    • pp.732-738
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    • 1999
  • Background: Video-assisted thoracoscopic surgery has become a standard therapy for several diseases such as pneumothorax, hyperhidrosis, mediastinal mass, and so on. These methods usually required single-lung ventilation with double-lumen endobronchial tube to collapse the lung under general anesthesia. However, risks of general anesthesia itself and single-lung ventilation must be considered in high-risk patients. Material and method: Between December 1997 and July 1998, eight high-risk patients (6: empyema, 1: intractable pleural effusion, 1: idiopathic pulmonary fibrosis) with underlying pulmonary disease and poor general condition were treated by video-assisted thoracoscopic surgerys under epidural anesthesia and spontaneous breathing. Result: Video-assisted thoracoscopic surgerys were successfully per formed in 7 patients. Conversion to general anesthesia was required in 1 patient because of decrease in spontaneous breathing. But, conversion to open decortication was not required. In two patients with chronic empyema, one patient required thoracoplasty as a second procedure and one patient required re-video-assisted thoracoscopic procedure due to a recurrence. The mean operative time was 31.8$\pm$15.2 minutes. No significant postoperative respiratory com plication was encountered. Conclusion: Video-assisted thoracoscopic surgerys can be per formed safely under epidural anesthesia for the treatment of empyema and diagnosis of pulmonary abnormalities in high-risk patients.

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Pharmacological Evidence that Cromakalim Inhibits $Ca^{2+}$ Release from Intracellular Stores in Porcine Coronary Artery

  • Rhim, Byung-Yong;Hong, Sun-Hwa;Kim, Chi-Dae;Lee, Won-Suk;Hong, Ki-Whan
    • The Korean Journal of Physiology and Pharmacology
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    • v.1 no.1
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    • pp.27-34
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    • 1997
  • In the present study, it was aimed to further indentify the intracellular action mechansm of cromakalim and levcromakalim in the porcine coronary artery. In intact porcine coronary arterial strips loaded with fura-2/AM, acetylcholine caused an increase in intracellular free $Ca^{2+}$ $([Ca^{2+}]_i)$ in association with a contraction in a concentration-dependent manner. Cromakalim (1 ${\mu}M$) caused a reduction in acetylcholine-induced increased $[Ca^{2+}]_i$ not only in the mormal physiological salt solution (PSS) but also in $Ca^{2+}$-free PSS (containing 1 mM EGTA). In the skinned strips prepared by exposure of tissue to 20 .${\mu}M$ B-escin, inositol 1,4,5-trisphosphate ($IP_3$) evoked an increase in $[Ca^{2+}]_i$, but it was without effect on the intact strips. The $IP_3$-induced increase in $[Ca^{2+}]_i$ was inhibited by cromakalim by 78% and levcromakalim by 59% (1 .${\mu}M$, each). Pretreatment with glibenclamide (a blocker of ATP-sensitive $K^+$ channels, 10 .${\mu}M$) and apamin (a blocker of small conductance $Ca^{2+}$-activated $K^+$ channels, 1 .${\mu}M$) strongly blocked the effect of cromakalim and levcromakalim. However, charybdotoxin (a blocker of large conductance $Ca^{2+}$-activated $K^+$ channels, 1 .${\mu}M$) was without effect. In addition, cromakalim inhibited the $GTP{\gamma}S$ (100 .${\mu}M$, non-hydrolysable analogue of GTP)-induced increase in $[Ca^{2+}]_i$. Based on these results, it is suggested that cromakalim and levcromakalim exert a potent vasorelaxation, in part, by acting on the $K^+$ channels of the intracellular sites (e.g., sarcoplasmic reticulum membrane), thereby, resulting in decrease in release of $Ca^{2+}$ from the intracellular storage site.

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A Study on the Separation of Electrolyte from Amino Acid Solution through Electrodialysis (전기투석법을 이용한 아미노산으로부터 전해질 분리정제에 관한 연구)

  • 김석곤;한정우;김한성;전경용;조영일
    • Membrane Journal
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    • v.4 no.3
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    • pp.163-170
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    • 1994
  • The separation of inorganic salt from amino acid solution using was performed electrodialysis. In order to review the availability of electrodialysis using isoelectric point of amino acid as a bio-separation technique, electrodialysis stacks were designed using ion exchange membrane. Separation of NaCl from amino acid solution was performed in the condition similar to amino acid fermentation process. To obtain otimum conditions of separation, leakage of amino acid depending of pH and limiting current density were measured. On the basis of optimum condition, removal of NaCl and leakage of amino acid were investigated quantitatively in batch and continuous process, and current efficiencies were also obtained. As a result of batch experiment for 11 hours each amino acid solution, removal efficiencies of NaCl were in the ranges of 96.1~96.2%. Amino acid leakage rate of glycine, methionine, alanine were 2.5, 1.7, 2.0% respectively. Current efficiencies were in the ranges of 44.5~44.6%. As a result of continuous experiment in various flow rate of each amino acid solution, it took 120 ~ 150 min to reach to steady state. Removal efficiency of NaCl was increased as the flow rate was decreased, but current efficiency was decreased. At the steady states, there were no leakage of amino acid.

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Effect of Rootzone Mixes Amended with Crumb Rubber on the Physical Properties (폐 타이어 고무칩을 혼합한 개량제의 물리성 개선 효과)

  • Chong, She-Kong;Ok, Chang-Ho
    • Asian Journal of Turfgrass Science
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    • v.20 no.1
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    • pp.83-91
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    • 2006
  • This research was initiated to enhance the tilth of fine-textured soil for turf growth by incorporation of crumb rubber shredded from used tires. A specific objective was to determine the physical properties of soil mixes amended with different grade and amount of crumb rubber in soils. Two soils and three different grades(3.5, 6.5 and 9.5 mm) of crumb rubber were used. The soils selected were an Arenzville silt loam(coarse-silty, mixed, nonacid, mesic Typic Udifluvents) and a Hosmer silty clay loam(fine-silty, mixed, mesic Typic Fragiudalfs). The amount of crumb rubber mixed in soil ranged from 0 to 0.4 $g{\cdot}g^{-1}$(using 0.05 $g{\cdot}g^{-1}$) increments and 0 as a control. For each treatment, soil cores were constructed following the recommendation by the United States Golf Association Green Section Record. Results indicated that porosity of the mixes decreased as the amount of crumb rubber increased. Regardless of the grade of crumb rubber, mixes with less than 0.15 $g{\cdot}g^{-1}$ of crumb rubber in fine-textured soil could not enhance their macro-porosity and hydraulic conductivity. However, as the amendment increased over 0.15 $g{\cdot}g^{-1}$, the tilth of the mixes had improved significantly macro-porosity, hydraulic conductivity and air permeability, as compared with a control.

Scanning Electron Microscopic Study on the Wax Structures in Lipstick According to Storage Temperature After Mold (립스틱 성형 후 보관온도에 따른 왁스구조의 주사전자현미경적 연구)

  • Kwon, Rok-Hee;Chang, Byung-Soo
    • Applied Microscopy
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    • v.42 no.1
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    • pp.43-48
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    • 2012
  • This study shows that ceresin wax, candellila wax and microcrystalline wax mixed together with liquid paraffin oil to produce lipsticks (LS-1, LS-2) and capric/caprylic triglyceride oil added to produce lipsticks (LS-3, LS-4). After each type of lipsticks were molded, LS-1 and LS-3 was put into a cooling chamber ($5^{\circ}C$). LS-2 and LS-4 was put into a cooling chamber ($5^{\circ}C$) for 18 hours and kept in an incubator ($45^{\circ}C$) for 5 hours and put again into a cool chamber ($5^{\circ}C$). After that, the wax's three dimensional network structure was observed under scanning electron microscopy. Regardless of the kind of oil, the LS-1 and LS-3 wax structure had more distinct shape than the lipstick wax structure of LS-2 and LS-4. Also, regardless of the kind of wax, the three dimensional network structure was modified as the storage temperature increased. As a result, the lipstick's molding temperature increased, the wax's structure size also increased and the shape irregularly modified. This modification causes sweating phenomenon which affected lipstick's surface rheological property.

Synthesis and Photovoltaic Properties of Alternating Conjugated Polymers Derived from Thiophene-Benzothiadiazole Block and Fluorene/Indenofluorene Units

  • Li, Jianfeng;Tong, Junfeng;Zhang, Peng;Yang, Chunyan;Chen, Dejia;Zhu, Yuancheng;Xia, Yangjun;Fan, Duowang
    • Bulletin of the Korean Chemical Society
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    • v.35 no.2
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    • pp.505-512
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    • 2014
  • A new donor-accepter-donor-accepter-donor (D-A-D-A-D) type 2,1,3-benzothiadiazole-thiophene-based acceptor unit 2,5-di(4-(5-bromo-4-octylthiophen-2-yl)-2,1,3-benzothiadiazol-7-yl)thiophene ($DTBTTBr_2$) was synthesized. Copolymerized with fluorene and indeno[1,2-b]fluorene electron-rich moieties, two alternating narrow band gap (NBG) copolymers PF-DTBTT and PIF-DTBTT were prepared. And two copolymers exhibit broad and strong absorption in the range of 300-700 nm with optical band gap of about 1.75 eV. The highest occupied molecular orbital (HOMO) energy levels vary between -5.43 and -5.52 eV and the lowest unoccupied molecular orbital (LUMO) energy levels range from -3.64 to -3.77 eV. Potential applications of the copolymers as electron donor material and $PC_{71}BM$ ([6,6]-phenyl-$C_{71}$ butyric acid methyl ester) as electron acceptors were investigated for photovoltaic solar cells (PSCs). Photovoltaic performances based on the blend of PF-DTBTT/$PC_{71}BM$ (w:w; 1:2) and PIF-DTBTT/$PC_{71}BM$ (w:w; 1:2) with devices configuration as ITO/PEDOT: PSS/blend/Ca/Al, show an incident photon-to-current conversion efficiency (IPCE) of 2.34% and 2.56% with the open circuit voltage ($V_{oc}$) of 0.87 V and 0.90 V, short circuit current density ($J_{sc}$) of $6.02mA/cm^2$ and $6.12mA/cm^2$ under an AM1.5 simulator ($100mA/cm^2$). The photocurrent responses exhibit the onset wavelength extending up to 720 nm. These results indicate that the resulted narrow band gap copolymers are viable electron donor materials for polymer solar cells.

Dependence of Coercivity and Exchange Bias as Surface Magnetic Anisotropy in [Pd/Ferromagnet] Multilayer with Out-of-plane Magnetic Anisotropy (수직자기이방성을 갖는 [Pd/Ferromagnet] 다층막에서 표면자기이방성에 따른 교환력과 보자력의 의존성)

  • Heo, Jang;Kim, Hyun-Shin;Choi, Jin-Hyup;Lee, Ky-Am
    • Journal of the Korean Magnetics Society
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    • v.18 no.3
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    • pp.98-102
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    • 2008
  • Dependence of the exchange bias and coercivity as surface magnetic anisotropy and ferromagnet materials for $[Pd/Co]_N$ and $[Pd/Co,(CoFe)]_N$/FeMn multilayers with perpendicular magnetic anisotropy were investigated. The coercivity was proportionally increased to 670 Oe by increasing stack number N in Ta(2.1 nm)/[Pd(3.1/N)/$Co(1.2/N)]_N$/Ta(2.1) multilayers with perpendicular magnetic anisotropy. Also, the coercivity in exchange biased multilayer was tend to increased by increasing stack number N. But coercivity of each materials have been in order of Co (600 Oe), $Co_5Fe_5$ (520 Oe) and $Co_8Fe_2$ (320 Oe) as function of the ferromagnet materials. The other side, exchange force of each materials is 300 Oe when the reiteration layer number N is 3. In over number of reiteration layer 3, they maintained coercivity between 200 Oe and 300 Oe.

A Novel Analysis Of Amorphous/Crystalline Silicon Heterojunction Solar Cells Using Spectroscopic Ellipsometer (Spectroscopic Ellipsometer를 이용한 a-Si:H/c-Si 이종접합 태양전지 박막 분석)

  • Ji, Kwang-Sun;Eo, Young-Ju;Kim, Bum-Sung;Lee, Heon-Min;Lee, Don-Hee
    • New & Renewable Energy
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    • v.4 no.2
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    • pp.68-73
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    • 2008
  • It is very important that constitution of good hetero-junction interface with a high quality amorphous silicon thin films on very cleaned c-Si wafer for making high efficiency hetero-junction solar cells. For achieving the high efficiency solar cells, the inspection and management of c-Si wafer surface conditions are essential subjects. In this experiment, we analyzed the c-Si wafer surface very sensitively using Spectroscopic Ellipsometer for < ${\varepsilon}2$ > and u-PCD for effective carrier life time, so we accomplished < ${\varepsilon}2$ > value 43.02 at 4.25eV by optimizing the cleaning process which is representative of c-Si wafer surface conditions very well. We carried out that the deposition of high quality hydrogenated silicon amorphous thin films by RF-PECVD systems having high density and low crystallinity which are results of effective medium approximation modeling and fitting using spectroscopic ellipsometer. We reached the cell efficiency 12.67% and 14.30% on flat and textured CZ c-Si wafer each under AM1.5G irradiation, adopting the optimized cleaning and deposition conditions that we made. As a result, we confirmed that spectroscopic ellipsometry is very useful analyzing methode for hetero-junction solar cells which need to very thin and high quality multi layer structure.

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Soft Magnetic Property Analysis of Nanocrystalline Fe-Al-O Film with the Change of Microstructure (나노 결정립 Fe-Al-O 산화막의 미세구조 변화에 따른 연자기적 특성 분석)

  • Lee, Young-Woo;Park, Bum-Chan;Kim, Chong-Oh;Moon, Ji-Hyun;Choi, Yong-Dae
    • Journal of the Korean Magnetics Society
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    • v.14 no.2
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    • pp.59-64
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    • 2004
  • We investigated the soft magnetic properties of nanocrystalline Fe-Al-O film as etching the oxide film with ion beam etching method. It is thought that the grain size of Fe-Al-O film increases as the thickness decreases. The coercivity and squareness increase with decreasing thickness. The surface curvature of Am images increases when the etching experiment proceeds. This phenomena could be due to the grain growth which occurs during sputtering. This grain growth could be assisted by the the plasma energy during sputtering. Therefore proper thickness should be searched to acquire the good soft magnetic properties for the nanocrystalline film material. Good soft magnetic properties of Fe-Al-O film was acquired at the thickness of more than 900 nm.