• Asian Pacific Journal of Cancer Prevention
• /
• v.14 no.5
• /
• pp.3085-3091
• /
• 2013

Associations between ABCB1 and XPC genetic polymorphisms and risk of developing colorectal cancer (CRC) as well as clinical outcomes in CRCs with chemotherapy were investigated. A case-control study was performed on the ABCB1 C3435T, G2677T/A and XPC Lys939Gln polymorphisms in 428 CRC cases and 450 hospitalbased, age and sex frequency-matched controls using polymerase chain reaction-restriction fragment length polymorphism (PCR-RFLP) assays. We observed that the ABCB1 3435CT or CC+CT variants were significantly linked with increasing risk of developing CRC (adjusted OR (95% CI): 1.814 (1.237-2.660), P=0.0022; adjusted OR (95% CI): 1.605 (1.117-2.306), P=0.0102, respectively). Moreover, the distribution frequency of XPC AC genotype or AC+CC genotypes also showed a tendency towards increasing the suscepbility for CRC (P=0.0759 and P=0.0903, respectively). Kaplan-Meier curves showed that the ABCB1 C3435T variant was associated with a tendency toward longer progression-free survival (PFS) (n=343, Log-rank test: P=0.063), and the G2677T/A variant genotypes (GT+TT+GA+AA) with a tendency for longer OS in postoperative oxaliplatin-based patients (n=343, Log-rank test: P=0.082). However, no correlation of the XPC Lys939Gln polymorphism was found with PFS and OS in patients with postoperative oxaliplatin-based chemotherapy (n=343). Our study indicated that ABCB1 polymorphisms might be candidate pharmacogenomic factors for the prediction of CRC susceptibility, but not for prognosis with oxaliplatin chemosensitivity in CRC patients.

• Journal of Korea Society of Industrial Information Systems
• /
• v.25 no.5
• /
• pp.91-102
• /
• 2020

The Internet of Things (IoT) is characterized as the market where various companies compete for the same consumers. Thus, there are differences in functions and performance provided by the main business area and other characteristics of the service providers. This paper investigates whether satisfaction with the service provided depends on the characteristics of the operator by using sentiment analysis of comments. To achieve this goal, word importance analysis and sensitivity analysis are conducted on 34,310 reviews of 41 applications registered in the Google Play. The review analysis was conducted at various levels, including TD-IDF (Term frequency-inverse document frequency) value of keywords, service sectors, the origin of providers, and domestic/foreign providers. The results show that users' overall assessment of IoT services was found to be low, and smart homes received relatively high reviews compared to other services, and manufacturing-based and overseas providers received relatively higher evaluations than others.

• Journal of Advanced Navigation Technology
• /
• v.27 no.1
• /
• pp.71-76
• /
• 2023

In this paper, a humidity sensor using a microstrip patch antenna(MPA) and polyvinyl alcohol(PVA) is studied. PVA is a polymer material whose permittivity changes with humidity, and a rectangular slot is added to the radiating edge of the MPA, which is sensitive to changes in electric field, in order to increase the sensitivity to changes in relative permittivity. After thinly coating the area around the radiating edge with the rectangular slot of the MPA fabricated on a 0.76 mm-thick RF-35 substrate with PVA, the changes in the resonant frequency and magnitude of the MPA's input reflection coefficient are measured when relative humidity is adjusted from 40% to 80% in 10% increments at a temperature of 25 degrees using a temperature and humidity chamber. Experiment results show that when the relative humidity increases from 40% to 80%, the resonance frequency of the antenna' input reflection coefficient decreases from 2.447 GHz to 2.418 GHz, whereas the magnitude increases from -7.112 dB to -3.428 dB.

• Journal of Advanced Navigation Technology
• /
• v.28 no.1
• /
• pp.136-141
• /
• 2024

In this paper, a broadband inset-fed microstrip patch antenna operating at 10.525 GHz band was proposed. The proposed broadband inset-fed microstrip patch antenna consists of three narrow rectangular patches. At the center of the center patch, two symmetrical side patches were connected by a strip conductor and were arranged with their centers shifted in a perpendicular direction with respect to the center patch. For performance comparison, a conventional inset-fed square microstrip patch antenna was designed. Experiment results show that the frequency band of the measured input reflection coefficient with a voltage standing wave ratio less than 2 for the broadband inset-fed microstrip patch antenna was 10.036-11.051 GHz (9.63%), whereas that for the conventional inset-fed rectangular microstrip patch antenna was 10.306-10.772 GHz (4.42%). Therefore, the input reflection coefficient frequency bandwidth of the fabricated broadband inset-fed microstrip patch antenna was increased by 2.18 times, compared to the conventional inset-fed square microstrip patch antenna.

• Korean Journal of Veterinary Service
• /
• v.43 no.3
• /
• pp.167-171
• /
• 2020

The epidemiological investigation of outbreak in korea confirmed that the inflow of avian influenza (AI) is related to the migration of migratory birds. In this study, avian repellents instrument were implemented and developed using the visual effects of lasers in accordance with the situation of small domestic fowl farms, and monitoring cameras were installed around each instrument to investigate the frequency of wild birds appearing and evaluate the performance of the instrument. Observation showed that the appreance ratio was reduced by 95%, and no significant reduction in the intrusion prevention effect by adaptation was observed on all fowl farms. In conclusion, it is expected that the outbreak of wild bird-borne infectious diseases such as avian influenza will be decreased if the device is installed on domestic fowl farms.

• Smart Structures and Systems
• /
• v.19 no.2
• /
• pp.137-149
• /
• 2017

Under the interference of the temperature effect, the alternation of cable force due to damages of a cable-stayed bridge could be difficult to distinguish. Considering the convenience and applicability in engineering practice, simple air or cable temperature measurements are adopted in the current study for the exclusion of temperature effect from the variation of cable force. Using the data collected from Ai-Lan Bridge located in central Taiwan, this work applies the ensemble empirical mode decomposition to process the time histories of cable force, air temperature, and cable temperature. It is evidently observed that the cable force and both types of temperature can all be categorized as the daily variation, long-term variation, and high-frequency noise in the order of decreasing weight. Moreover, the correlation analysis conducted for the decomposed variations of all these three quantities undoubtedly indicates that the daily and long-term variations with different time shifts have to be distinguished for accurately evaluating the temperature effect on the variation of cable force. Finally, consistent results in reducing the range of cable force variation after the elimination of temperature effect confirm the validity and stability of the developed method.

• Journal of Electrical Engineering and Technology
• /
• v.12 no.6
• /
• pp.2268-2277
• /
• 2017

As constantly increasing wind power penetrates power grid, wind power plants (WPPs) are exerting a direct influence on the traditional power system. Most of WPPs are using variable speed constant frequency (VSCF) wind turbines equipped with doubly fed induction generators (DFIGs) due to their high efficiency over other wind turbine generators (WTGs). Therefore, the analysis of DFIG has attracted considerable attention. Precisely measuring optimum reference speed is basis of utilized maximum wind power in electric power generation. If the measurement of wind speed can be easily taken, the reference of rotation speed can be easily calculated by known system's parameters. However, considering the varying wind speed at different locations of blade, the turbulence and tower shadow also increase the difficulty of its measurement. The aim of this study is to design fuzzy controllers to replace the wind speedometer to track the optimum generator speed based on the errors of generator output power and rotation speed in varying wind speed. Besides, this paper proposes the fuzzy adaptive PID control to replace traditional PID control under rated wind speed in variable-pitch wind turbine, which can detect and analyze important aspects, such as unforeseeable conditions, parameters delay and interference in the control process, and conducts online optimal adjustment of PID parameters to fulfill the requirement of variable pitch control system.

• Journal of the Korean Operations Research and Management Science Society
• /
• v.22 no.3
• /
• pp.37-58
• /
• 1997

An AI approach with tabu search is designed to solve multi-level knapsack problems. The approach performs intelligent actions with memories of historic data and learning effect. These action are developed ont only by observing the attributes of the optimal solution, the solution space, and its corresponding path to the optimal, but also by applying human intelligence, experience, and intuition with respect to the search strategies. The approach intensifies, or diversifies the search process appropriately in time and space. In order to create a good neighborhood structure, this approach uses two powerful choice rules that emphasize the impact of candidate variables on the current solution with respect to their profit contribution. "Pseudo moves", similar to "aspirations", support these choice rules during the evaluation process. For the purpose of visiting as many relevant points as possible, strategic oscillation between feasible and infeasible solutions around the boundary is applied. To avoid redundant moves, short-term (tabu-lists), intemediate-term (cycle-detection), and long-term (recording frequency and significant solutions for diversfication) memories are used. Test results show that among the 45 generated problems (these problems pose significant or insurmountable challenges to exact methods) the approach produces the optimal solutions in 39 cases.lutions in 39 cases.

• Proceedings of KOSOMES biannual meeting
• /
• 2005.11a
• /
• pp.71-74
• /
• 2005

This paper describes Fishery Safety and Security System using F-AIS based on the concepts of RFID(Radio Frequency Identification). This system is to track, protect and arrest the thief who invaded in an fishing ground. The system composed with various functional modules to implement selectively available system providing low cost to high cost and simple function to high function according to user's requirement in a practical fishing fields. Sea trial tests are carried out at Mokpo, Busan and Incheon and, it is found that the system can guard the wide area of cultivating farm field.

• Asian Pacific Journal of Cancer Prevention
• /
• v.16 no.6
• /
• pp.2209-2213
• /
• 2015

DNA methylation of tumor suppressor gene promoters is the most frequent phenomenon leading to inactivation of function, consequently driving malignant cell transformation. Cyclin D2 is implicated in tumor suppression. In our study, we carried out the MSP assay to evaluation the methylation status at CpG islands in the cyclin D2 promoter in breast cancer cases from the Vietnamese population. The results showed that the frequency of methylation reached 62.1% (59 of 95 breast cancer tumors), but was low in non-cancer specimens at 10% (2 of 20 non-cancer specimens). Additionally, with an RR (relative risk) and OR (odd ratios) of 6.21 and 14.8, DNA hypermethylation of cyclin D2 increased the possibility of malignant transformation. Our results confirmed the cyclin D2 hypermethylation could be used as the potential biomarker which could be applied in prognosis and early diagnosis of Vietnamese breast cancer patients.