• Journal of the Korea Institute of Information and Communication Engineering
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• v.8 no.7
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• pp.1442-1447
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• 2004

In this paper, a 6-Bit CMOS Folding and Interpolating AD Converter is presented. The converter is considered to be useful as an integrated part of a VLSI circuit handling both analog and digital signals as in the case of HDD or LAN applications. A built-in analog circuit for VLSI of a high-speed data communication requires a small chip area, low power consumption, and fast data processing. The proposed folding and interpolating AD Converter uses a very small number of comparators and interpolation resistors, which is achieved by cascading a couple of folders working in different principles. This reduced number of parts is a big advantage for a built-in AD converter design. The design is based on 0.25m double-poly 2 metal n-well CMOS process. In the simulation, with the applied 2.5V and a sampling frequency of 500MHz, the measurements are as follows: power consumption of 27mw, INL and DNL of $\pm$0.1LSB, $\pm$0.15LSB each, SNDR of 42dB with an input signal of 10MHz.

• Proceedings of the IEEK Conference
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• 2003.11c
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• pp.239-242
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• 2003

이 논문에서는 기존 연구 활동에 쓰이는 NS-2 시뮬레이터와 최근 대만의 National Chiao Tung University에서 개발하여 주목을 받고 있는 네트워크 시뮬레이터인 NCTUns에서 On-Demand 방식의 Ad Hoc 라우팅 프로토콜 중 AODV와 DSR의 성능을 분석하여 그 결과를 논하였다. NCTUns의 경우 작은 규모의 실험에서는 원할 한 성능을 보여주지만 노드수가 증가하면 불안정한 성능을 보여준다. 그러나 NS-2의 경우 NCTUns가 보여준 문제점 없이 원할 한 통신을 보여준다. 이에 앞으로의 실험에서는 Ad Hoc 관련 실험에서 보다 안정적인 성능을 보이고 있는 NS-2의 프로토콜 모듈을 NCTUns에 보강하면 보다 안정적인 시뮬레이터가 될 것으로 기대한다.

• Journal of Ginseng Research
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• v.40 no.1
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• pp.9-17
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• 2016

Background: Alzheimer's disease (AD) is a progressive brain disease, for which there is no effective drug therapy at present. Ginsenoside Rg1 (G-Rg1) and G-Rg2 have been reported to alleviate memory deterioration. However, the mechanism of their anti-AD effect has not yet been clearly elucidated. Methods: Ultra performance liquid chromatography tandem MS (UPLC/MS)-based metabolomics was used to identify metabolites that are differentially expressed in the brains of AD mice with or without ginsenoside treatment. The cognitive function of mice and pathological changes in the brain were also assessed using the Morris water maze (MWM) and immunohistochemistry, respectively. Results: The impaired cognitive function and increased hippocampal $A{\beta}$ deposition in AD mice were ameliorated by G-Rg1 and G-Rg2. In addition, a total of 11 potential biomarkers that are associated with the metabolism of lysophosphatidylcholines (LPCs), hypoxanthine, and sphingolipids were identified in the brains of AD mice and their levels were partly restored after treatment with G-Rg1 and G-Rg2. G-Rg1 and G-Rg2 treatment influenced the levels of hypoxanthine, dihydrosphingosine, hexadecasphinganine, LPC C 16:0, and LPC C 18:0 in AD mice. Additionally, G-Rg1 treatment also influenced the levels of phytosphingosine, LPC C 13:0, LPC C 15:0, LPC C 18:1, and LPC C 18:3 in AD mice. Conclusion: These results indicate that the improvements in cognitive function and morphological changes produced by G-Rg1 and G-Rg2 treatment are caused by regulation of related brain metabolic pathways. This will extend our understanding of the mechanisms involved in the effects of G-Rg1 and G-Rg2 on AD.

• 한국노년학
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• v.30 no.4
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• pp.1197-1211
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• 2010

This research was concucted to present a model of advance directives(AD) when a patient, who is in consciousness, shows a preference for an end of life care as an act of preparing for an uncertain situation that may arise in the forseeable future. The subjects of the research are 383 doctors/nurese and adults, who live in six cities and provinces, to investigate the status of AD, attitude regarding a meaningless life-prolonging treatment, and moreover, an understanding of and a preference for AD. The research was done by the well-structured questionnaire. Also, SPSS 14.0 is used to analyse the collected data, focused on frequency analysis, avearage and standard deviation, X2 test. As the results of the study, the most of the surveyed doctors/nurese knew DNR orders and AD and a few of them used DNR orders and AD practically. Also, the result shows that there is a negative conception of meaningless life-prolonging treatment among the responents, in addition, most of them agreed upon the idea of introducing AD to Korea, filling it out and making it legally effective. As a method of making AD out, the respondents wanted to use a form that mixed living will with an Power of Attorney in a document. Also, considering the appropriate time, respondents prefered when they are diagnosed with terminal illness. At the moment, the introductory model for AD, which is suitable for the Korean culture and current situation is presented based on the result of this research. In the future, other researches should deal with specific measures that can lead to a social consensus to adopt AD in Korea.

• The Journal of Korean Institute of Communications and Information Sciences
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• v.33 no.2C
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• pp.167-172
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• 2008

Since a 2-dimensional (2D) bar code can retrieve data and information quickly, it is widely used and recognized as a useful tool for many industrial applications. However, the information capacity of the 2D bar code is still limited. Recently the analog-digital code (AD code), which has the largest storage capacity yet contained in a code, has been developed, thereby expanding the bar code's application range because it overcomes the limitation of data capacity. In this paper, we present the AD code and implement an effective embedded system which can transform text information into voice using the 2D AD code and Text To Speech (TTS). This voice information can also be transmitted to blind people as well as the old by capturing the AD code on paper or in books.

• Journal of Korea Society of Digital Industry and Information Management
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• v.18 no.2
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• pp.9-16
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• 2022

The nodes constituting the vehicle ad hoc network (VANET) are vehicles moving along the road and road side units (RSUs) installed around the road. The vehicle ad hoc network is used to collect the status, speed, and location information of vehicles driving on the road, and to communicate with vehicles, vehicles, and RSUs. Today, as the number of vehicles continues to increase, urban roads are suffering from traffic jams, which cause various problems such as time, fuel, and the environment. In this paper, we propose a method to solve traffic congestion problems on urban roads and demonstrate that the method can be applied to solve traffic congestion problems through performance evaluation using two typical protocols of vehicle ad hoc networks, AODV and GPSR. The performance evaluation used ns-2 simulator, and the average number of traffic jams and the waiting time due to the average traffic congestion were measured. Through this, we demonstrate that the vehicle ad hoc-based traffic congestion management technique proposed in this paper can be applied to urban roads in smart cities.

• The Journal of Korean Society of Virology
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• v.26 no.1
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• pp.23-30
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• 1996

대략 36,000 base pairs (bp)의 두 가닥짜리 DNA를 지놈으로 가진 사람 아데노바이러스 (Ad)는 DNA 상동성(相同性) 및 생물학적/생화학적 성격이 특이한 49개의 혈청형이 알려져 있는데, 이들 대부분의 Ad가 영유아군 및 면역능이 저하된 성인에서 치사적 결과를 초래할 수 있다. Ad의 세포향성(向性)(tropism)은 매우 다양하여 종류에 따라 상기도 감염, 각결막염, 영유아 장염등을 유발하는데 최근 Ad의 다양한 병원성에 대한 원인을 분자생물학적 수준에서 규명하려는 노력의 일환으로 지역에 따라 주되게 출현하는 Ad형 규명이 활발히 이루어지고 있다. Ad 동정/확인은 표면을 이루고 있는 group 공통항원인 hexon 단백질을 탐지하는 효소면역 측정법 (EIA)에 의하며, Ad형별은 Ad fiber의 세포독성 중화시험에의 한다. 그러나, 세포독성 중화시험이 엄청난 노동력 및 시간을 요구하면서도 민감도/특이도가 만족스럽지 못하여 이를 개선하기 위하여 검체 또는 세포배양에서 Ad DNA를 추출하여 제한효소 절단형태를 비교하는 방법이 개발되었는데 이는 세포배양에 잘 자라지 않는 바이러스주의 형별뿐만 아니라 지역 분리주들의 지놈 변형주를 관찰하는 분자생물학적/분자역학적 연구에도 도움이 되고 있다. 국내에는 Ad와 관련된 소아장염의 빈도가 rotavirus에 의한 것 다음으로 빈번한데도 Ad40/41외에 주되게 출현하는 장내 Ad형들이 전혀 규명된 바 없고, 한국형 Ad들의 지놈형태가 전혀 보고된 바가 없다. 또한 세계적으로 Ad형별 조사지역이 늘어감에 따라 유아장염과 연관된 Ad 역시 Ad40, 41이 외의 형들이 Ad40, 41을 능가하는 것으로 보고되고 있는 지역도 있으나 국내에서는 Ad40, 41이외의 형들은 그 역학적 중요도가 전혀 알려져 있지 않다. 이로서 본 연구의 목적은 Ad주들에 특이 중화항체를 이용한 세포독성 중화시험과 Ad DNA 절단법을 적용하여 한국형 장내 Ad주들의 형별을 처음으로 시도함과 동시에 1989-1991사이 출현한 Ad들의 유전적 변형을 관찰하려는 것이었다. 두 방법 모두 사용하였을 때 주되게 출현하는 장내 Ad형들은 Ad4l, Ad2, Ad7, Ad5, 및 Ad40이었다. Ad40/41-양성 검체를 제외한 Ad hexon-EIA양성들의 77.5%를 형별 할 수 있었던 Ad DNA의 제한효소 절단방법은 형들간의 교차중화로 특이성이 낮았던 중화방법 (47.5%)보다 매우 효율적이어서 두 가지 방법을 함께 적응하였을 때는 40주중의 81.5%인 35주를 형별 할 수 있었다. 또한Ad DNA 제한 효소 절단방법은 Ad7 변이주 (Ad7b)도 탐지 할 수 있었다.

• Proceedings of the Korea Institutes of Information Security and Cryptology Conference
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• 2003.07a
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• pp.89-92
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• 2003

Diffie-Hellman(DH) 키공유 기법［1］이 제안된 후 많은 종류의 키공유 기법들이 연구되었으며, 특히 특정한 그룹 내의 구성원들이 안전한 통신을 할 수 있게 하기 위한 그룹 기반의 키공유 기법들에 대한 많은 방식들이 제안되었다. 이러한 방식들은 PKI 기반 구조 등을 사용하는 여러 응용들에서 쉽게 사용될 수 있지만, Ad-hoc 통신망이라는 특정한 기반구조를 사용할 수 없는 환경에서는 적용하기가 쉽지 않다. ［2］에서는 Ad-hoc 환경에서의 그룹(conference) 기반의 키공유 기법을 제안하였지만, (n＋2)-라운드의 통신량이 요구되며, 그룹 구성원들의 위치정보를 알고 있어야 한다. 본 논문에서는 ad-hoc 환경에서의 효율적이며, 그룹 구성원들의 위치정보를 알 필요 없는 2-라운드 키공유 기법을 제안한다.

• The Journal of Korean Institute of Electromagnetic Engineering and Science
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• v.28 no.11
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• pp.880-885
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• 2017

In AD-MUSIC algorithm, DOD/DOA can be estimated without computationally expensive two-dimensional search. In this paper, to further reduce the computational complexity, the Newton type method has been applied to one-dimensional search. In this paper, we summarize the formulation of the AD-MUSIC algorithm, and present how to apply Newton-type iteration to AD-MUSIC algorithm for improvement of the accuracy of the DOD/DOA estimates. Numerical results are presented to show that the proposed scheme is efficient in the viewpoints of computational burden and estimation accuracy.

• Journal of Hospice and Palliative Care
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• v.19 no.2
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• pp.109-118
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• 2016

The purpose of this study was to evaluate Korean advance directives (K-AD) by examining the degree of adults' acceptance and reliability of the directive itself. Methods: Survey was performed with 181 adults aged 20 or older who were recruited from three regions. A questionnaire used to examine the participants' acceptance of their K-AD in terms of visual analogue scale score of complexity, difficulty, necessity, satisfaction, recommendation. Then, a retest was carried out by asking participants to write up a K-AD again to confirm the reliability of the directives. Results: On a scale of 100, the average acceptance score was 70 or above, which represents rather high level of acceptance in all five categories. The test-retest reliability kappa values ranged from 0.592 to 0.950, and the conformity degree was moderate or high. Regarding K-AD components such as values, treatment preference, proxy appointment, differences among age groups were observed in each component. Conclusion: The results of this study suggest that K-AD is a feasible instrument to analyze its acceptability and reliability for adult population. K-AD could be utilized to help people make their own decision on their end-of-life care. Further studies are needed to confirm this study results and promote widespread use of K-AD.