• Title/Summary/Keyword: ABT-5

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A Study on Seaweed Sea Staghorn(Codium fragile) Ethanol Extract for Antioxidant (해조류 청각(Codium fragile) 에탄올 추출물의 항산화에 관한 연구)

  • Lee, Ju-Hee;Kim, Bo-Ae
    • The Journal of the Convergence on Culture Technology
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    • v.5 no.4
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    • pp.467-472
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    • 2019
  • Seaweeds are rich in in minerals, vitamins, proteins, and fiber, and are classified as green algae, and they are distributed on the coasts of Korea, East Asia, Oceania, etc. and are used as a health function material as well as food ingredients in our countries and countries. In this study, Codium fragile was extracted from ethanol and concentrated to confirm DPPH radical scavenging activity, SOD activity, FRAP and ABTS cation radical scavenging ability. As a result, DPPH scavenging activity was 0.83, 22.83, 38.27, 40.93, 45.60% at 6.25, 12.50, 25, 50 and $100{\mu}g/mL$, SOD-like activity were 23.13, 33.63, 33.93, 44.07 and 59.07%. FRAP and ABTS showed antioxidant activity in a concentration-dependent manner, as in the previous experiment. Therefore, this study confirmed that it can be used as a cosmetic material using Codium fragile, a natural material.

Antioxidant and Anti-inflammatory activity of Saccharomycopsis fibuligera fermented Lindera obtusiloba flower extract (Saccharomycopsis fibuligera 발효 생강나무 꽃 추출물의 항산화 및 항염효과)

  • Park, Sang-Nam;Yoon, Joong-Soo;Lee, Ok-Hee
    • Journal of Convergence for Information Technology
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    • v.11 no.11
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    • pp.296-303
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    • 2021
  • In this study, the antioxidant activity and anti-inflammatory activity of Lindera obtusiloba flower fermentation extracts were identified. To evulate antioxidant activity and antioxidant concentration, polyphenol concentration measurements, flavonoid concentrations measurements, DPPH experiments, and ABTS experiments were conducted. In Flavonoids, DPPH and ABTS assay, antioxidant activity were increased after fermentation. At this time, the flavonoid concentration was 5.0%, the DPPH experiment showed 33.27% and the ABTS experiment showed 29.82% antioxidant increase. In the anti-inflammatory experiment, we conducted a cytotoxicity experiment and an anti-inflammatory experiment for LPS-induced inflammation. Cytotoxicity showed low cytotoxicity in both control and fermentation groups, but lower cytotoxicity in fermentation groups. In the case of NO production inhibition, fermented Lindera obtusiloba flowers showed an increase in anti-inflammatory activity by more than 50% compared to the control group, showing that they can be used as a cosmetic ingredient with anti-inflammatory function.

Antioxidant Activities of the Extracts of Herbs Used for Gamhongro-ju (감홍로주 제조에 사용하는 재료 침출액의 항산화 효과)

  • Lee, Sae-Rom;Shin, Hye-Hyun;Hwang, Keum-Taek;Jeong, Seok-Tae;Kim, Tae-Young
    • Journal of the Korean Society of Food Science and Nutrition
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    • v.39 no.5
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    • pp.643-647
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    • 2010
  • Gamhongro-ju is a Korean traditional alcoholic beverage made from medicinal herbs and spices. In this study, polyphenol content and antioxidant activities of gamhongro-ju and the 8 individual herb extracts used to make the beverage were determined. Cinnamon, saposhnikovia root, clove, ginger, violet-root cromwell, licorice, citrus peel and logan (2.5 g each) were extracted with 1000 mL of 45% and 60% purified ethanol (PE), and 45% traditionally distilled ethanol (TDE). The individual herb (20 g each) was extracted with 1000 mL of 60% PE. Polyphenol content, DPPH and ABTS radical scavenging activities of the extracts were measured. In the combined herb extracts, polyphenols were significantly higher in the 45% and 60% PE extracted for 90 days than those for 30 days. In the 8 individual herb extracts, the clove extract had the highest polyphenol content (2421~2446 mg/L). ABTS $IC_{50}$ values of the combined herb extracts were lower in the 60% PE and 45% TDE extracted for 90 days than those for 30 days. In the 8 individual herb extracts, the clove and cinnamon had the lowest ABTS and DPPH $IC_{50}$ values. In the individual extracts, ginger had the lowest polyphenol content; however, it was the third in the antioxidant activity.

Comparison of Phytochemical and Antioxidant Activities in Different Color Stages and Varieties of Paprika Harvested in Korea (국내산 파프리카의 색상별 phytochemical 및 항산화능 비교)

  • Kim, Ji-Sun;Ahn, Ji-Yun;Ha, Tae-Youl;Rhee, Han-Cheol;Kim, Sun-A
    • Korean Journal of Food Science and Technology
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    • v.43 no.5
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    • pp.564-569
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    • 2011
  • This study qualitatively and quantitatively analyzed various carotenoids, L-ascorbic acid, and tocopherol and their anti-oxidant properties from four varieties (Special, Chelsea, Cupra, and Fiesta) and three different color stages [green (GP), yellow (YP) and red (RP)] of paprika harvested in Korea. Seven carotenoids were identified, mainly lutein in GP (Special: 4.65${\pm}$0.84 mg/kg fresh weight (fw)) and YP (Fiesta: 5.19${\pm}$0.05 mg/kg fw), and capsorubin (3.16${\pm}$0.35 mg/kg fw) and capsanthin (53.70${\pm}$6.23 mg/kg fw) in Special of RP. RP was the highest in total carotenoids, L-ascorbic acid, and ${\alpha}$-tocopherol contents, while GP was the highest in ${\gamma}$-tocopherol content. RP showed the strongest antioxidant activity ($IC_{50}$=62.40${\pm}$0.03 ${\mu}g/mL$ in an ABTS assay and 182.77${\pm}$31.74 ${\mu}g/mL$ in a DPPH assay). Paprika in different color stages has many phytochemicals even though they have different kinds of carotenoids. Therefore, dietary intake of paprika may be helpful for improving human health.

Antioxidant Components and Antioxidant Activities of Methanolic Extract from Adzuki Beans (Vigna angularis var. nipponensis) (품종별 팥 메탄올 추출물의 항산화성분 및 항산화활성)

  • Woo, Koan-Sik;Song, Seuk-Bo;Ko, Jee-Yeon;Seo, Myung-Chul;Lee, Jae-Saeng;Kang, Jong-Rae;Oh, Byeong-Geun;Nam, Min-Hee;Jeong, Heon-Sang;Lee, Jun-Soo
    • Korean Journal of Food Science and Technology
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    • v.42 no.6
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    • pp.693-698
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    • 2010
  • In this study, the antioxidant compounds and antioxidant activities of adzuki beans were measured to evaluate their functional properties and to compare them to Daepung and Taekwang. Proximate compositions and mineral contents of the various adzuki beans were not significantly different. A high level of dietary fiber (14.81%) was found in Chilbopat. The extraction yields of Daepung and Taekwang were 38.70 and 34.61%, respectively; however the yields of the various adzuki beans were lower at 13.78-20.76%. The total polyphenol and flavonoid content of the various adzuki beans were 19.00-34.75 and 12.97-28.95 mg/g, respectively (Daepung: 14.40 and 3.96 mg/g, Taekwang: 10.7 and 2.61 mg/g). High levels of polyphenols (34.75 mg/g) and flavonoids (28.95 mg/g) were found in Miryang 6. The total anthocyanin and proanthocyanidin contents of the various adzuki beans ranged from 5.89-23.77 and 1.83-3.29 mg/g, respectively. A high level of total tocopherol content (7.66 mg/100 g) was found in Yungum-pat. High levels of ABTS radical (2.44 mg TEAC/mg extract residue) and DPPH radical scavenging activities (4.46 mg TEAC/mg extract residue) were found in Miryang 6. A significant correlation was also noted between free radical scavenging activity and polyphenolic compound content. The results of this study suggest that notable antioxidant activities in various adzuki beans could have significant health benefits.

Analysis of Functional Components in Roasted Okra (Abelmoschus esculentus L. Moench) Seeds (볶음 오크라 종자의 주요 기능성분 분석)

  • Ahn, Yul Kyun;Jang, Ki Chang;Kim, Shun Hwan
    • Journal of Bio-Environment Control
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    • v.22 no.1
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    • pp.61-64
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    • 2013
  • This study was conducted to investigate the general characteristics of raw okra seeds and the functional components of roasted okra seeds. The number of okra seed per pod was 78 in 'Greensod' and 88 in 'Beny'. The weight of okra seed per pod of 'Greensod' and 'Beny' were 4.4 g and 6.3 g, respectively. Free amino acid contents of the stir-fry and fresh okra seeds were measured as $2.69mg{\cdot}g^{-1}$ and $0.31mg{\cdot}g^{-1}$. Total polyphenolic compound content of the stirfry okra seeds was estimated as $12.61mg\;CGA{\cdot}g^{-1}$, compared to $2.54mg\;CGA{\cdot}g^{-1}$ fresh okra seeds, Thus, free amino acid and total polyphenolic compound contents in the stir-fry okra seeds were higher than fresh one, Antioxidant activities, such as DPPH and ABTS radical scavenging in the stir-fry okra seeds was the higher than fresh okra seeds.

Effect of Lactobacillus plantarum FH185 on the Reduction of Adipocyte Size and Gut Microbial Changes in Mice with Diet-induced Obesity

  • Park, Sun-Young;Cho, Seong-A;Lee, Myung-Ki;Lim, Sang-Dong
    • Food Science of Animal Resources
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    • v.35 no.2
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    • pp.171-178
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    • 2015
  • This study aimed to investigate the effects of Lactobacillus plantarum FH185 on the reduction of adipocyte size and gut microbial changes in mice with diet-induced obesity. The strain was found to have a lipase inhibitory activity of 70.09±2.04% and inhibited adipocyte differentiation of 3T3-L1 cells (18.63±0.98%) at a concentration of 100 µg/mL. To examine the effect of the strain supplementation on gut microbial changes in mice with diet-induced obesity, male C57BL/6J mice were fed on four different diets (i.e., A, normal diet (ND); B, high-fat diet (HFD); C, HFD with ABT-3 (109 CFU/day); and D, HFD with L. plantarum FH185 (109 CFU/day)) for 6 wk. According to the results of fecal pyrosequencing, the ratio of Firmicutes to Bacteroidetes in groups C and D was lower than in the control groups at the phylum level. At the family level, Lactobacillaceae in groups C and D was observed to dominate, while Lachnospiraceae in groups A and B was observed to dominate. At the genus level, Lactobacillus in groups C and D was comparatively higher than in groups A and B. To examine the effects of strain supplementation on the reduction of adipocyte size, the left and right epididymal fat pads were quickly isolated after the animals were sacrificed, and the adipocyte sizes were measured. In groups A, C and D, the percentage of 2,000 m2 of adipocyte was higher than in the other size of adipocyte, while the percentage of over 5,000 m2 of adipocyte was highest in group B. The mean adipocyte size of group D was significantly larger than that of group A, but smaller than that of group B.

Antioxidant and Anti-wrinkling Effects of Extracts from Vitex trifolia L. (만형자 추출물의 항산화 및 주름개선 효과)

  • Lee, Mi-Kyoung;Kim, Dong-Hee;Park, Tae-Soon;Son, Jun-Ho
    • Journal of Applied Biological Chemistry
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    • v.58 no.2
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    • pp.125-129
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    • 2015
  • In this study, the antioxidant and anti-wrinkling effects of fraction from Vitex trifolia L. were investigated. Among the fractions, ethyl acetate fraction showed the highest antioxidant activities in 1-1-diphenyl-2-picryl-hydrazyl, 2,2'-azino-bis(3-ethylbenzothiazoine-6-sulfonic acid) radical scavenging and elastase inhibition with 76, 89, and 74%, respectively, at a concentration of $1,000{\mu}g/mL$. This fraction, at the concentration of $25{\mu}g/mL$, inhibited 70% fibroblast cell viability and 86% the matrix metalloprotease (MMP)-1. In addition, the results from Western blot assay showed that this fraction ($25{\mu}g/mL$) expressed the MMP-1 protein level by decreasing 50%. The findings suggest that the ethyl acetate fraction from V. trifolia has great potential as a cosmeceutical ingredient with antioxidant and anti-wrinkling effects.

다문화사회를 위한 의식개선 사업에 관한 연구

  • Jeong, Ji-Yun;Gang, Gyeong-Sik
    • Proceedings of the Safety Management and Science Conference
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    • 2011.04a
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    • pp.461-470
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    • 2011
  • 우리나라는 정부차원에서 교육과학기술부, 문화체육관광부, 여성가족부, 보건복지가족부, 법무부, 지방자치단체 등 관련 부처별로 필요한 분야에 한해 다문화 강사 양성이 이루어지고 있다. 교육과학기술부에서는 2007년 다문화가정 자녀교육 지원계획을 발표하고 2008년부터 각 교육청 주관으로 다문화교육 직무연수를 외부에 위탁하여 중앙 및 각 지방 다문화교육센터를 중심으로 현직교사 대상 '다문화교육을 위한 교사 양성 연수 프로그램'을 지속적으로 운영하고 있다. 문화체육관광부 산하 한국문화예술교육진흥원에서는 2008년에 다문화강사 양성과정을 개설하여 운영하였다. 그리고 여성부는 청소년, 이주노동자, 이주여성을 대상으로 다문화교육을 제공할 목적으로 2008년에 '다문화이해교육 강사양성' 과정을 개설하였다. 그러나 이들은 모두 일회성에 머물러 지속적으로 연계되지는 못했다. 또한 보건복지가족부는 2007년에 '결혼이민자 다문화가족 지원센터'에서 종하며 교육활동을 하기 위한 다문화 강사 80명을 일차적으로 양성하였다. 최근에는 각 지방자치단체별 다문화가족 지원센터에서 결혼이민자를 다문화 강사로 활용하여 청소년들에게 다문화 이해 교육을 제공하도록 하는 '다문화강사 양성과정'을 개별적으로 개설하여 운영하고 있다(설동훈 김찬기, 2009). 한편 법무부는 2008년 5월 다문화 이해증진 및 이민자 사회통합을 위한 정책개발 추진에 우수 대학의 적극적인 참여 기회를 부여하고, 관련 분야에 대한 대학의 새로운 학문 개척 기회를 마련하기 위해 공모 절차를 거쳐 20개의 ABT대학을 최종 선정하였다. 명지대학교는 2010년 3월부터 산업대학원 산업시스템경영학과 국제교류경영학석사 과정에서 국제교류경영 전문가 양성을 운영하고 있다. 경기도 지원 경기도의 새로운 브랜드 가치 실현을 위한 '다문화사회를 위한 의식개선 사업'으로 사회통합 - 다문화사회 공동체 형성을 목표로 총4개의 컨소시엄 기관(시흥시, 수원시, 화성시외국인복지센터, 의정부시외국인근로자지원센터)이 형성되어 2010년 2월22에서 2010년12월20까지 시행되었다. 본 연구는 '다문화사회를 위한 의식개선 사업'을 통해 교육대상자 구분과 사업장 교육 지역별 구분과 일반인 교육 지역별 구분을 파악하고 이를 기초로 우리의 다문화사회에 도움이 될 수 있는 다문화교육의 개선 방안을 제시하고자 한다.

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Koreanische $\"{U}bersetzungsm\"{o}glichkeiten$ von Modalpartikel 'doch' (독일어 양상불변화사 doch의 우리말 번역 가능성)

  • Kim Hui-Cha
    • Koreanishche Zeitschrift fur Deutsche Sprachwissenschaft
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    • v.5
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    • pp.223-251
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    • 2002
  • Modalpartikeln, die auch $Abt\"{o}nungspartikeln,\;W\"{u}rzw\"{o}rter,\;F\"{a}rbew\"{o}rter$ usw. genannt werden, galten eine Zeitlang als $\"{U}berfl\"{u}ssiges$. Aber mit der 'kommunikativ­pragrnatischen Wende' hat die Partikelforschung einen enormen Aufschwung genommen. Auch im Femdsprachenunterricht waren Partikeln als etwas Unwichtiges oder in anderen Worten etwas schwer zu Behandelndes geblieben und wurden deshalb zur Seite geschoben. Mit Hilfe der Aufschwung der Partikelforschung in Deutschland untersuchte ich koreanische $\"{U}bersetzungsm\"{o}glichkeiten$ von Modalparikeln. Ich $\"{u}bernahm$ Diewaldische Methode. Sie $schl\"{a}gt$ ein Beschreibungsschema vor: Modalpartikeln haben verweisende und $verkn\"{u}fende$ Funktion. Sie weisen $n\"{a}hmlich$ auf den pragmatischen $Pr\"{a}text\;zur\"{u}ck$ und bringen ihn in relevanter Situation mit der Modalpartikel enthaltenden $\"{A}u{\ss}erung$ in Beziehung. Da braucht man also drei Ebenen: pragmatischer $Pr\"{a}text$, relevante Situation und partikelhaltige $Au{\ss}erung$. Die Schwierigkeit der $\"{U}bersetzungsm\"{o}glichkeiten$ von Modalkartikeln besteht darin, jeweiligen $Pr\"{a}text$ und jeweilige relevante Situation wiederherzustellen und auszudrticken. In diesem Aufsatz geht es nur um 'doch'. 'doch' ist eine der $h\"{a}ufigsten$ Modalpartikeln und tritt in vielen verschidenen Satzarten. 'doch' tritt in Aussage-, Imperativ-, Ausrufe­und Wunschsatzen auf. $Au{\ss}erdem$ tritt 'doch' in $Erg\"{a}nzungsfragen$ und Entscheidungsfragen mit Intonation auf und ist aber nur bei 'echten' Fragen ausgeschlossen. Aus der diachronischen Bedeutungsentwicklung und dem Bedeutungsvergleich zu ihren Homonymen stellten sich die semantischen Merkmale von 'doch' als $Adversativit\"{a}t\;und\;Konzessivit\"{a}t$. Aber diese semantischen Komponenten werden bei dem Modalpartikel $abgeschw\"{a}cht$ und pragmatische Faktoren werden in verschiedenen $Verwendungsm\"{o}glichkeiten$ verstarkt. Unter $Ber\"{u}cksichtigung\;jeweiligen\;Pr\"{a}textes$ und relevanter Situation schlug ich koreanische $\"{U}bersetzungsm\"{o}glichkeiten$ von 'doch' je nach der Satzart und nach der $Verwendungsm\"{o}glichkeit$ vor.

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