• Tuberculosis and Respiratory Diseases
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• 제69권5호
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• pp.375-380
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• 2010

Lymphoid interstitial pneumonia (LIP) is a rare benign lymphoproliferative interstitial lung disease. LIP has been associated with autoimmune disorders, HIV, viral infections, and so on. Once underlying systemic diseases have been excluded, a diagnosis of idiopathic LIP can be made. Although 6 cases of pathologically confirmed LIP have occurred in Korea, thus far none has been associated with primary Sjogren's syndrome. A 44-year-old man was admitted to hospital due to a dry cough and dypsnea on exertion that had been ongoing for 2 months. A chest radiography showed multiple and variable-sized cystic lesions, on both lungs and both interstitial infiltration and consolidation in both lower lung fields. Tests for autoantibody showed positive results of anti-nuclear antibody and anti-Ro/La antibody. The patient underwent a video assisted thoracoscopic surgery biopsy and pathologically confirmed LIP. We report the first known case of LIP-associated with primary Sjogren's syndrome in Korea.

• 산업공학
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• 제17권3호
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• pp.375-383
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• 2004

The purpose of this study is to investigate the characteristics of vibration induced by the powered hand tools used in the automobile assembly lines, and estimate the prevalence of vibration syndrome. The acceleration levels of four major powered hand tools were measured using the ISO 5349 method along with the time of exposure to the vibration of the hand tools. Four-hour-energy-equivalent frequency-weighted accelerations ranged from $1.27m/s^2$ to $2.58m/s^2$, After exposure to vibration for 12.6 years, about 10% of the workers using impact ranches were expected to develop Raynaud's disease. For the workers using grinders, 16.6% of the workers were expected to develop Raynaud's disease. The results would be of help in developing the guidelines of local vibration control.

• Journal of Astronomy and Space Sciences
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• 제20권4호
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• pp.375-382
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• 2003

위성을 설계함에 있어 질량제어 계획을 작성하고 질량자료를 유지하며 시스템의 질량특성을 계산하고 제어하는 것은 기계 시스템 담당자가 수행하는 임무 중에 하나이다. 위성의 질량특성은 자료수집, 특성예측 그리고 실제 측정의 순서로 설계 및 제작이 진행됨에 따라 수행된다. 질량특성 데이터베이스는 설계과정을 통하여 작성하게 되며 질량특성 측정 시험을 수행하여 데이터베이스의 신뢰성을 확인할 수 있어야 한다. 본 논문에서는 위성에서의 질량 제어계획의 일반적인 내용과 시스템 수준의 질량중심 및 관성 모멘트 계산과 관련된 여러 가지 구체적인 사항을 고려한 이론적 질량 특성 데이터베이스를 개발하고, 다목적실용위성 2호 개발을 수행하면서 얻게 된 실제적인 자료와 경험을 토대로 본 연구에서 개발된 데이터베이스의 신뢰성을 확인하였다.

• 전기전자학회논문지
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• 제18권4호
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• pp.447-455
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• 2014

본 연구에서는 4H-SiC MOSFET의 주요 문제점인 $SiC/SiO_2$ 계면의 특성을 향상시키기 위해 PECVD (plasma enhanced chemical vapor deposition) 공정을 이용하여 n-based 4H-SiC MOS Capacitor를 제작하였다. 건식 산화 공정의 낮은 성장속도, 높은 계면포획 밀도와 $SiO_2$의 낮은 항복전계 등의 문제를 극복하기 위하여 PECVD와 NO어닐링 공정을 사용하여 MOS Capacitor를 제작하였다. 제작이 끝난 후, MOS Capacitor의 계면특성을 hi-lo C-V 측정, I-V 측정 및 SIMS를 이용해 측정하고 평가하였다. 계면의 특성을 건식 산화의 경우와 비교한 결과 20% 감소한 평탄대 전압 변화, 25% 감소한 $SiO_2$ 유효 전하 밀도, 8MV/cm의 증가한 $SiO_2$ 항복전계 및 1.57eV의 유효 에너지 장벽 높이, 전도대 아래로 0.375~0.495eV만큼 떨어져 있는 에너지 영역에서 69.05% 감소한 계면 포획 농도를 확인함으로써 향상된 계면 및 산화막 특성을 얻을 수 있었다.

• Experimental and Molecular Medicine
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• 제50권12호
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• pp.13.1-13.12
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• 2018

We aimed to explore whether changes in circulating levels of miRNAs according to type 2 diabetes mellitus (T2DM) or prediabetes status could be used as biomarkers to evaluate the risk of developing the disease. The study included 462 patients without T2DM at baseline from the CORDIOPREV trial. After a median follow-up of 60 months, 107 of the subjects developed T2DM, 30 developed prediabetes, 223 maintained prediabetes and 78 remained disease-free. Plasma levels of four miRNAs related to insulin signaling and beta-cell function were measured by RT-PCR. We analyzed the relationship between miRNAs levels and insulin signaling and release indexes at baseline and after the follow-up period. The risk of developing disease based on tertiles (T1-T2-T3) of baseline miRNAs levels was evaluated by COX analysis. Thus, we observed higher miR-150 and miR-30a-5p and lower miR-15a and miR-375 baseline levels in subjects with T2DM than in disease-free subjects. Patients with high miR-150 and miR-30a-5p baseline levels had lower disposition index (p = 0.047 and p = 0.007, respectively). The higher risk of disease was associated with high levels (T3) of miR-150 and miR-30a-5p ($HR_{T3-T1}=4.218$ and $HR_{T3-T1}=2.527$, respectively) and low levels (T1) of miR-15a and miR-375 ($HR_{T1-T3}=3.269$ and $HR_{T1-T3}=1.604$, respectively). In conclusion, our study showed that deregulated plasma levels of miR-150, miR-30a-5p, miR-15a, and miR-375 were observed years before the onset of T2DM and pre-DM and could be used to evaluate the risk of developing the disease, which may improve prediction and prevention among individuals at high risk for T2DM.

• 한국의류학회지
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• 제28권2호
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• pp.364-375
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• 2004

The purpose of this study is to analyze how the men＇s fashion with the representation of Feminization which has appeared on our specialized fashion magazine from 1990 though 2003. Firstly, the factor which exposed the representation of Feminization in men＇s fashion were the change of conventional sex role, the change of ideal beauty, the variety of information, the pursuit of personality and the polycentrism of thought. Secondly, the formative characteristics of Feminization in men＇s fashion represented fitted silhouettes which distinctively show the body line, elastic fabric and see-through fabric of androgynous image, accessory and wave hair which expressed in gentle image. In colors, it represented vivid tone, pastel tone, red colors and yellow colors. Fitted silhouttes and elastic fabric has a effect of minimalism of the last 1990＇s fashion, and wave hair of gentle image has a effect of change of ideal beauty since 2000. Therefore, elements of representation of Feminization in men＇s fashion were silhoutte, fabric, color, accessory, hairstyle and the representation of feminity in men＇s fashion has referance to fashion.

• Journal of the Optical Society of Korea
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• 제19권4호
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• pp.371-375
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• 2015

The impact of equivalent optical bandwidth on the performance of a system using a reflective electroabsorption modulator (R-EAM) based optical source has been experimentally evaluated with signals operating at 2.5 Gb/s and beyond. The equivalent optical bandwidth of our source with a broadband seed light was simply adjusted by using a bandwidth tunable optical filter. From the measurements, we have estimated the required equivalent optical bandwidth of our source for an error-free transmission (@ bit-error-rate of $10^{-12}$) and a forward error correction (FEC) threshold of $2{\times}10^{-4}$.

• Parasites, Hosts and Diseases
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• 제50권4호
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• pp.375-377
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• 2012

Malaria is still a leading cause of morbidity and mortality. The increase in lipid peroxidation reported in malaria infection and antioxidant status may be a useful marker of oxidative stress during malaria infection. The aim of this study was to investigate the role of antioxidant enzymes against toxic reactive oxygen species in patients infected with Plasmodium vivax and healthy controls. Malondialdehyde levels, superoxide dismutase, and glutathione peroxidase activities were determined in 91 P. vivax patients and compared with 52 controls. Malondialdehyde levels, superoxide dismutase, and glutathione peroxidase activities were $8.07{\pm}2.29$ nM/ml, $2.69{\pm}0.33$ U/ml, and $49.6{\pm}3.2$ U/g Hb in the patient group and $2.72{\pm}0.50$ nM/ml, $3.71{\pm}0.47$ U/ml, and $62.3{\pm}4.3$ U/g Hb in the control group, respectively. Malondialdehyde levels were found statistically significant in patients with vivax malaria higher than in healthy controls (P<0.001). On the other hand, superoxide dismutase and glutathione peroxidase activities were found to be significantly lower in vivax malaria patients than in controls (P<0.05). There was an increase in oxidative stress in vivax malaria. The results suggested that antioxidant defense mechanisms may play an important role in the pathogenesis of P. vivax.

• 콘크리트학회논문집
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• 제22권3호
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• pp.375-380
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• 2010

이 연구에서는 파이넥스 슬래그 미분말을 혼합한 시멘트(OPC-FS)의 물성을 유동성, 압축강도, 수화열 및 $Ca(OH)_2$ 측정을 통해 알아보고, 비교를 위해 고로슬래그를 혼합한 시멘트(OPC-BFS)에서도 동일한 시험을 수행하였다. 유동성은 두 혼합시멘트에서 유사한 경향으로 나타났고, 비표면적 $4,000\;cm^2/g$에서 OPC-FS가 OPC-BFS보다 유동성이 우수하였다. 모르타르 압축강도 시험 결과 초기재령 3일에서 OPC-FS의 강도가 OPC-BFS보다 향상되었고, 수화열 측정 결과도 높게 나타났다. 또한 열분석 결과로부터 OPC-FS의 경우 수화반응을 위한 $Ca(OH)_2$의 급격한 소모를 확인할 수 있었다.

• Advances in materials Research
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• 제11권4호
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• pp.375-390
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• 2022

Carbon Fiber Reinforced Polymer (CFRP) composite provides outstanding mechanical capabilities and is therefore popular in the automotive and aerospace industries. Drilling is a common final production technique for composite laminates however, drilling high-strength composite laminates is extremely complex and challenging. The delamination of composites during the drilling at the entry and exit of the hole has a severe impact on the results of the holes surface and the material properties. The major goal of this research is to investigate contemporary industry solutions for drilling CFRP composites: enhanced edge geometries of cutting tools. This study examined the occurrence of delamination at the entry and exit of the hole during the drilling. For each of the 80°, 90°, and 118°point angle uncoated Brad point, Dagger, and Twist solid carbide drills, Taguchi design of experiments were undertaken. Cutting parameters included three variable cutting speeds (100-125-150 m/min) and feed rates (0.1-0.2-0.3 mm/rev). Brad point drills induced less delamination than dagger and twist drills, according to the research, and the best cutting parameters were found to be a combination of maximum cutting speed, minimum feed rate, and low drill point angle (V:150 m/min, f: 0.1 mm/rev, θ: 80°). The feed rate was determined to be the most efficient factor in preventing hole entry and exit delamination using analysis of variance (ANOVA). Regression analysis was used to create first-degree mathematical models for each cutting tool's entrance and exit delamination components. The results of optimization, mathematical modelling, and experimental tests are thought to be reasonably coherent based on the information obtained.